• Journal of Gastric Cancer
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• v.12 no.4
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• pp.210-216
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• 2012

Purpose: To assess independent prognostic factors for lymph node-negative metastatic gastric cancer patients following curative resection is valuable for more effective follow-up strategies. Materials and Methods: Among 1,874 gastric cancer patients who received curative resection, 967 patients were lymph node-negative. Independent prognostic factors for overall survival in lymph node-negative gastric cancer patients grouped by tumor invasion depth (early gastric cancer versus advanced gastric cancer) were explored with univariate and multivariate analyses. Results: There was a significant difference in the distribution of recurrence pattern between lymph node-negative and lymph nodepositive group. In the lymph node-negative group, the recurrence pattern differed by the depth of tumor invasion. In univariate analysis for overall survival of the early gastric cancer group, age, macroscopic appearance, histologic type, venous invasion, lymphatic invasion, and carcinoembryonic antigen level were significant prognostic factors. Multivariate analysis for these factors showed that venous invasion (hazard ratio, 6.695), age (${\geq}59$, hazard ratio, 2.882), and carcinoembryonic antigen level (${\geq}5$ ng/dl, hazard ratio, 3.938) were significant prognostic factors. Multivariate analysis of advanced gastric cancer group showed that depth of tumor invasion (T2 versus T3, hazard ratio, 2.809), and age (hazard ratio, 2.319) were prognostic factors on overall survival. Conclusions: Based on our results, independent prognostic factors such as venous permeation, carcinoembryonic antigen level, and age, depth of tumor invasion on overall survival were different between early gastric cancer and advanced gastric cancer group in lymph node-negative gastric cancer patients. Therefore, we are confident that our results will contribute to planning follow-up strategies.

• Journal of the Korean Institute of Landscape Architecture
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• v.31 no.4
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• pp.49-56
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• 2003

This study is to find physiological effects of acoustic information on landscape preference. Both the volume and the rate of $\alpha$-waves and $\beta$-waves were used to measure the effects in the study. The result of this study are summarized as follows: The outputting amount of $\alpha$-waves are sorted by different types of visual and acoustic factors. The results show that acoustic factors interacted with visual factors. That is, although visual factors are positive, the volume of $\alpha$-waves depends upon the character of acoustic factors; positive acoustic factors produce more $\alpha$-waves than negative or neutral(soundless) acoustic factors. Also the volume of $\alpha$-waves increase in the case of positive acoustic factors even if there is the same negative visual information. The results show that the volume of $\alpha$-waves increase without connecting with the types of visual factors. The volume of $\beta$-waves are largely reduced when visual stimulus is positive and soundless stimulus is provided. On the other hand, they generally increase when both visual and acoustic stimuli are negative, which fosters extremely unstable, tense and upset stress. The rate of $\alpha$-waves increase according to supplying positive acoustic factors in the opposed visual factors. The rate of wave(shouldn't be $\alpha$-waves\ulcorner) is high if both visual and acoustic factors are positive, so it is the most comfortable and causes no stress. Preference is the lowest if visual and acoustic factors are negative, but a -waves are conspicuously low in positive visual and negative acoustic factors.

• Journal of Environmental Science International
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• v.29 no.4
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• pp.403-413
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• 2020

The purpose of this study is to understand the formation of internal wind paths of open space and its effect on meteorological factors and the generation of negative air ions. Various types of internal wind paths of open space were formed. Subsequently, changes in meteorological factors in each type were measured and the generated negative air ions were analyzed. The four key findings of the study are summarized as follows. First, the average wind speed formed inside the open space was analyzed such that the difference in wind speed was dependent on the difference in the composition of the wind path. Second, the negative air ion generation was observed to have the same trend as the average wind speed difference. Third, changes to the meteorological factors were more evident depending on the difference in wind path formation patterns. Solar radiation was expected to be highly affected by the physical structure (direction) of the target site. The relative humidity was found to show large difference depending on the different wind path type; however, this difference was significantly reduced when converting to absolute humidity. Fourth, it was found that the wind path formation type of open space affects meteorological factors through path analysis, and the changed meteorological factors affect the amount of generated negative air ions. Two conclusions can be obtained based on these results. First, the changes in internal wind speed formation of open space directly reduced the amount of generated negative air ions. Second, the changes in wind speed affect meteorological factors as well as the amount of generated negative air ions.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.2
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• pp.1037-1041
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• 2013

Background: Prognostication of breast cancer using clinico-pathologic variables, although useful, remains imperfect. Recent research has focused on finding new markers of prognosis using gene expression profiling. Panels of proteins assessed by immunohistochemistry might also be useful in this regard. This study focused on Bcl-2 protein expression in triple-negative (TNBC) and non- triple-negative breast cancer (non-TNBC) with correlation to clinico-pathologic variables. Materials and methods: We analyzed Bcl-2 expression in 77 women with primary breast carcinoma divided into two groups; triple-negative and non- triple-negative according to expression of estrogen (ER), progesterone (PR) and human epidermal growth factor receptors (Her2/neu). Bcl-2 expression was assessed in relation to age, histo-pathological subtype, grade, nodal status and tumor size. Results: Bcl-2 was expressed in 74% of triple-negative breast cancers and 70% of non- triple-negative cancers. In TNBC, expression was significantly correlated with invasive ductal subtype, while in non-TNBC it was significantly correlated with age and negative nodal status. In both groups higher Bcl-2 expression associated with favourable prognostic factors in breast cancer, but no significant statistical correlations were found. Conclusions: Frequency of Bcl-2 expression does not differ between TNBC and non-TNBC, but different prognostic factors correlate with Bcl-2 in the two cases.

• International Journal of Advanced Culture Technology
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• v.11 no.2
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• pp.358-365
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• 2023

As the Internet is used as a major channel for marketing and sales, the top ranking of search engine results is becoming a key competitor among websites. Various methods exist to maintain the top ranking of websites in search engines, typically investing heavily in organic coding or search engine optimization. The purpose of this paper, we present the ranking by recognizing factors that should be removed as negative factors when designing a web page in consideration of website visibility (SEO) because if website visibility is not met, the ranking may fall behind or be completely removed from the search engine index. The experiments that recognized and ranked the negative factors of website visibility proposed in this paper were provided through theory and experiments based on the existing website visibility analysis model. The models analyzed in this paper, we expressed or quantified as scores based on the methodology of each model, and 10 items were selected as negative factors through experiments and ranked as high scores. Therefore, when designing a website, it should be considered that the website is not removed from the search engine index as it is designed by excluding high-ranking items, which are negative factors.

• International Journal of Computer Science & Network Security
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• v.22 no.6
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• pp.241-245
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• 2022

The main purpose of the study is to determine the main factors influencing the economic environment of the region and its financial and economic security. Ukraine aspires to become a full member of the European Union, but the events of 2022 have changed everything. Full-scale military operations on the territory of Ukraine significantly affect its socio-economic situation Today, the issue of studying the negative impact of military operations on the economic environment is very relevant. Based on the results of the study, we have identified the main negative factors of the military impact on the economic environment of the region and its financial and economic security.

• Journal of Community Nutrition
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• v.2 no.2
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• pp.119-128
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• 2000

Lifestyle and dietary behavior intervention as the primary prevention of lipid disorder seems safe and compatible with other treatments of cardiovascular diseases. Cross-sectional associations between lifestyle factors and dietary behavioral factors with plasma lipid and lipoprotein levels were analyzed in 189 middle-aged men in Suwon, Korea. Overnight fasting plasma levels of total cholesterol, high-density lipoprotein(HDL)-cholesterol, triacylglycerol and glucose were analyzed. Blood pressure and anthropometric data were also measured. Lifestyle factors such as smoking status, alcohol consumption and frequency of physical exercise were evaluated by a self-administered questionnaire. Questions regarding dietary behavior were also asked. The subjects were 43.8%${\pm}$7.9 years old, and 23.8%${\pm}$2.6kg/m$^2$. From stepwise regression analyses, significant correlates with total cholesterol level were body mass index(BMI), alcohol intake(negative), age and coffee drinking(model R$^2$=14.3%). BMI, breakfast-skipping, age, and sleeping hours were significant for triacylglycerol level(model R$^2$=15.8%). BMI, alcohol drinking(negative), age, and coffee drinking were significant for low-density lipoprotein(LDL)(model R$^2$=11.7%). Age(negative), BMI(negative), alcohol drinking, stress level(negative), physical exercise, and cigarette smoking(negative) were significant for high-density lipoprotein(HDL)(model R$^2$=12.1%). From stepwise regression analyses, excluding BMI and age as factors in the model, alcohol intake(negative) and coffee drinking were significantly correlated with total cholesterol level(model R$^2$=4.4%) : breakfast-skipping with triacylglycerol(model R$^2$=3.2%) : alcohol intake (negative) with LDL level(model R$^2$=3.4%) : alcohol intake, physical exercise and stress level(negative) with HDL level(model R$^2$=6.3%). The findings suggest that a healthy daily lifestyle and dietary behavior may have an anti-atherogenic effect by altering plasma lipid and lipoprotein levels in middle-aged Korean men. (J Community Nutrition 2(2) : 119∼128, 2000)

• Journal of Convergence for Information Technology
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• v.10 no.2
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• pp.126-137
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• 2020

The purpose of this study is to analyze the impact factors on the happiness of teenagers using local children centers. To this end, 424 people were sampled and hierarchical regression methods were used using data from the 10th year of the Korea Children's Center Panel Study. The results are as follows. First, self-esteem and peer relation and service help in adolescents are found to have a static effect on happiness, of which self-esteem has the highest impact. Second, adolescent depression and negative parenting attitude have been shown to have a negative effect on happiness, and depression has a stronger negative impact than parents' negative parenting attitude. Accordingly, this study aims to highlight positive factors of influence and suggest alternatives for applying them to local children centers by developing various programs that can reduce negative factors in order to enhance the happiness of adolescents.

• Journal of Sport and Applied Science
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• v.3 no.2
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• pp.17-27
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• 2019

Purpose: This study is to conduct usability evaluations from the perspective of developing comfort-shoes for the middle-aged and elderly to identify key factors and derive implications for optimal comfort-shoes production. Research design, data, and methodology: A total of 10 middle-aged and elderly women in their 50s and 60s were selected as eligible for the rescue. For data collection, the study was conducted in a Gang Survey, where pre-explanations, shoes test, and interviews were conducted. The collected data were analyzed in a total of four stages. In step 1, the contents obtained through interviews with the subjects were recorded in text, organized and analyzed systematically, and in step 2, unnecessary vocabulary, sentences, and overlapping opinions were eliminated. In step 3, we classified areas around key functions and carried out categorization tasks. Finally, in Step 4, the results and implications of the study were derived by classifying each usability evaluation shoe as positive and negative text around categorized data. Results: There are a total of seven factors for comfort-shoes usability evaluation, which are categorized as cushion, fitting, stability, flexibility, lightweight, comfort, and pressure. Positive/negative factors for the derived usability evaluation factors were shown in the form of a positive-centered, negative-centered, and positive-mixed mix for each of the four products. Positive-focused products are VA products, which are seven times more positive than negative factors. Negative-centered products are CL and SA products, which are five times more negative than positive factors. Positive mixing was a CA product with a ratio of 1:1. Text-based usability evaluations allow us to proceed with analysis based on more scientific data rather than simply listening to opinions and judging by comments. Conclusions: The study discussed implications of developing comfort-shoes for middle-aged consumers and future directions were discussed.

• Journal of the korean academy of Pediatric Dentistry
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• v.11 no.1
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• pp.103-112
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• 1984

Eighty children, aged from 2 years 8 months to 5 years 1 month old, were examined to study the relationship between the preschool children's response at dental visit and the influencing factors. The results were as follows: 1, There was no significant relationship between the sexes and the children's response. 2. Children who experienced the painful dental treatment demonstrated significantly more negative dental response. 3. Children who stowed negative dental behavior at last dental visit demonstrated significantly more negative dental response. 4. Children of mothers with high anxiety scores demonstrated significantly more negative dental response. 5, Children who were unpleasant at hospitaization demonstrated significantly more negative dental response. 6. Children who thought they had dental problems demonstrated significantly the most negative dental response. 7. Children who abhorred the medical treatment demonstrated significantly more negative dental response.