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Lymphadenitis following intradermal BCG vaccination (피내용 BCG 접종 후 발생한 국소 림프절염)

  • Baek, Hey Sung;Chang, Ji Young;Moon, Su Ji;Oh, Sung Hee
    • Clinical and Experimental Pediatrics
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    • v.49 no.1
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    • pp.46-50
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    • 2006
  • Purpose : Intradermal BCG vaccine has not well been accepted by pediatric practitioners due to BCG lymphadenitis. Therefore, this study was undertaken to find out the incidence of lymphadenitis following intradermal BCG vaccination and its clinical outcome. Methods : One thousand and fifty infants, who received intradermal BCG(French 1173 P2, Korea Tuberculosis Association) vaccination in the Well Baby Clinic of Hanyang University Hospital from July 2001 to January 2004, were included in the study. Severe local reactions at the injection site and any mass noted on surrounding areas were reported to, and evaluated by, pediatricians. Surgical procedures, either surgical resection or needle aspiration, were recommended when lymph nodes progressed to suppurate without regression. Results : Twenty infants(1.9 percent) developed lymphadenitis 2 to 8 months following vaccination. The incidence of BCG lymphadenitis was significantly higher in infants born with intrauterine period of <38 weeks and birth weight of <2,700 g. The lymph nodes became suppurative in 7/17 infants (41.2 percent) and four infants required surgical procedures with which the rate for the requirement of surgical procedures among intradermal BCG vaccinnes approximated to be 0.45 percent. There was no correlation between the size of lymph nodes and suppuration, however surgical procedures were required significantly more often for lymph nodes of greater than 3 cm in diameter. Conclusion : The incidence of BCG lymphadenitis following intradermal BCG(French 1173 P2, Korea Tuberculosis Association) vaccinations would be more than 1.9 percent, when considering cases of lymphadenits not reported. More efforts need to be paid to decrease the incidence of BCG lymphadenitis in order to promote intradermal BCG vaccination in Korea.

Changes in Aboveground Biomass and Nutrient Accumulation of the Korean-pine (Pinus koraiensis) Plantation by Stand Age at kangwondo Province (강원도(江原道) 지방(地方) 잣나무 인공림(人工林)의 임령변화(林齡變化)에 따른 지상부(地上部) 현존량(現存量)과 양분축적(養分蓄積))

  • Yi, Myong-Jong
    • Journal of Korean Society of Forest Science
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    • v.87 no.2
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    • pp.276-285
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    • 1998
  • The aboveground biomass and nutrient content (N, P, K, Ca and Mg) of Pinus koraiensis S. et Z., aged 9, 22, 34, 46, 66 years, were measured in the Experiment Forest of Kangwon National University of Kangwondo province. The site index of the stands ranged from 13.5 to 14.2. Allometric equations (logY=alogX+b, where Y, X is ovendry mass and DBH, respectively) relating dry weights of stem, branches and needles to diameter at breast height (DBH) were developed to estimate aboveground tree biomass. Total above ground tree biomass increased with stand age from $21.8t\;ha^{-1}$ in the 9-year-old stand to $130t\;ha^{-1}$ in the 66-Year-old stand. Aboveground biomass was allocated as follows : stem> branch > foliage, except for the 9-year-old stand which had a greater proportion of foliage biomass than branch biomass. As stand age increased, an increasing proportion of annual biomass increment was allocated to stems. The aboveground biomass of shrubs and herbs ranged from 0.4 to $3.9t\;ha^{-1}$ and from 0.05 to $0.6t\;ha^{-1}$, respectively. No relationship was found between aboveground understory biomass and stand age. The mass of woody debris and forest floor varied between 0.59 to $1.54t\;ha^{-1}$ and 6.0 to $21.63t\;ha^{-1}$, respectively. Nutrient accumulation in aboveground tree biomass increased with stand age and was in the order of N > Ca > K > P > Mg. Average rates of nutrients accumulation in biomass were greatest in the early stages of stand development, and less marked as stand aged. The nutrient concentrations in different tree components decreased in the order of needle > branch > stem. There were no detectable trends in nutrient content of the forest floor and mineral soils with stand age. Understory vegetation contributed little to the nutrient pool of these Korean pine ecosystems. Mineral soil contained the Breast proportion of nutrient capital of the various ecosystem compartments.

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A STUDY ON IN VIVO AND IN VITRO AMALGAM CORROSION (아말감의 구강내 부식 및 인공 부식에 관한 연구)

  • Lim, Byong-Mok;Kwon, Hyuk-Choon;Um, Chung-Moon
    • Restorative Dentistry and Endodontics
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    • v.22 no.1
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    • pp.1-33
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    • 1997
  • The objective of this study was to analyze the in vitro and in vivo corrosion products of low and high copper amalgams. The four different types of amalgam alloy used in this study were Fine cut, Caulk spherical, Dispersalloy, and Tytin. After each amalgam alloy and Hg were triturated according to the directions of the manufacturer by means of the mechanical amalgamator(Amalgam mixer. Shinhung Co. Korea), the triturated mass was inserted into a cylindrical metal mold which was 12mm in diameter and 10mm in height. The mass was condensed by 150Kg/cm compressive force. The specimen was removed from the mold and aged at room temperature for about seven days. The standard surface preparation was routinely carried out by emery paper polishing under running water. In vitro amalgam specimens were potentiostatically polarized ten times in a normal saline solution at $37^{\circ}C$(potentiostat : HA-301. Hukuto Denko Corp. Japan). Each specimen was subjected to anodic polarization scan within the potential range -1700mV to+400mV(SCE). After corrosion tests, anodic polarization curves and corrosion potentials were obtained. The amount of component elements dissolved from amalgams into solution was measured three times by ICP AES(Inductive Coupled Plasma Atomic Emission Spectrometry: Plasma 40. Perkim Elmer Co. U.S.A.). The four different types of amalgam were filled in occlusal and buccal class I cavities of four human 3rd molars. After about five years the restorations were carefully removed after tooth extraction to preserve the structural details including the deteriorated margins. The occlusal surface, amalgam-tooth interface and the fractured surface of in vivo amalgam corrosion products were analyzed. In vivo and in vitro amalgam specimens were examined and analyzed metallographically by SEM(Scanning Electron Microscope: JSM 840. Jeol Co. Japan) and EDAX(Energy Dispersive Micro X-ray Analyser: JSM 840. Jeol Co. Japan). 1. The following results are obtained from in vitro corrosion tests. 1) Corrosion potentials of all amalgams became more noble after ten times passing through the in vitro corrosion test compared to first time. 2) After times through the test, released Cu concentration in saline solution was almost equal but highest in Fine cut. Ag and Hg ion concentration was highest in Caulk spherical and Sn was highest in Dispersalloy. 3) Analyses of surface corrosion products in vitro reveal the following results. a)The corroded surface of Caulk spherical has Na-Sn-Cl containing clusters of $5{\mu}m$ needle-like crystals and oval shapes of Sn-Cl phase, polyhedral Sn oxide phase. b)In Fine cut, there appeared to be a large Sn containing phase, surrounded by many Cu-Sn phases of $1{\mu}m$ granular shapes. c)Dispersalloy was covered by a thick reticular layer which contained Zn-Cl phase. d)In Tytin, a very thin, corroded layer had formed with irregularly growing Sn-Cl phases that looked like a stack of plates. 2. The following results are obtained by an analysis of in vivo amalgam corrosion products. 1) Occlusal surfaces of all amalgams were covered by thick amorphous layers containing Ca-P elements which were abraded by occlusal force. 2) In tooth-amalgam interface, Ca-P containing products were examined in all amalgams but were most clearly seen in low copper amalgams. 3) Sn oxide appeared as a polyhedral shape in internal space in Caulk spherical and Fine cut. 4) Apical pyramidal shaped Sn oxide and curved plate-like Sn-Cl phases resulted in Dispersalloy. 5) In Tytin, Sn oxide and Sn hydroxide were not seen but polyhedral Ag-Hg phase crystal appeared in internal space which assumed a ${\beta}_l$ phase.

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Langerhans Cell Histiocytosis in the Skull: Comparison of MR Image and Other Images (두개골의 랑게르한스 세포 조직구증: 자기공명영상과 다른 영상과의 비교)

  • Lim, Soo-Jin;Lim, Myung-Kwan;Park, Sun-Won;Kim, Jung-Eun;Kim, Ji-Hye;Kim, Deok-Hwan;Lee, Seok-Lyong;Suh, Chang-Hae
    • Investigative Magnetic Resonance Imaging
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    • v.13 no.1
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    • pp.74-80
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    • 2009
  • Purpose : To evaluate the characteristic MR imaging findings of Langerhans cell histiocytosis (LCH) in the skull and to compare them with those of plain radiography and computed tomography. Materials and Methods : A total of 10 lesions in 9 patients (Age range; 5-42 years, Mean age; 18, all women) with Langerhans cell histiocytosis in the skull were included in our study. Nine lesions in nine patients were histologically confirmed by surgery or fine needle aspiration biopsy. All patients performed with MRI, and plain radiography and CT scan were done in 7 patients (8 lesions). Two experienced neuroradiologists reviewed the radiological examinations independently with attention to location, size, shape and nature of the lesions in the skull and compared the extent and extension of the lesions to adjacent structures. Results : The lesions were distributed in all of the skulls without predilection site. On MRI, the masses were shown as well-enhancing soft tissue masses (10/10) mainly in diploic spaces (8/10) with extension to scalp (9/10) and dura mater (7/10). Dural enhancement (7/10) and thickening (4/10) were seen. The largest diameter of the soft tissue masses ranged 1.1 cm to 6.8 cm, shaped as round (5/10) or oval (5/10). On CT scans, the lesions were presented as soft tissue masses involving diploic space (6/8) and scalp extension (7/8) were also well visualized. Although bony erosion or destruction was more clearly seen on CT rather than those of MRI, enhancement of soft tissue masses and dura were not well visualized on CT. In contrast, all of the lesions in LCH were seen as punched out (4/8), beveled-edge appearance (4/8) osteolytic masses in plain radiography, but scalp and dural extension could not be seen. Conclusion : Characteristic MR findings in patients with LCH are soft tissue mass in diploic space with extension to dura and scalp, and MRI would be better imaging modality than plain radiography or CT.

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Giant Coronary Artery Aneurysm Presenting as a Calcified Mediastinal Mass a, Coronary Artery Fistula - A case report - (종격동 종양으로 오인된 거대관상동맥류와 관상동맥루 - 치험 1례 -)

  • Yoon, You-Sang;Lee, Cheol-Joo;Choi, Ho;Kang, Jun-Kyu;Choi, Jin-Wook;Kim, Hyung-Tae
    • Journal of Chest Surgery
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    • v.34 no.10
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    • pp.787-791
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    • 2001
  • Coronary artery aneurysm is a rare disorder. It is defined as abnormal dilatation of coronary artery with diameter exceeding 1.5 times the adjacent normal segments. The incidence of coronary aneurysm is 2.6% in Caucasians and 0.25% in Asians. Over half of the former were associated with atherosclerotic coronary artery disease. However, 70 percents of the latter were nonobstructive coronary artery aneurysms. Coronary artery fistula is a rare disorder. It has been identified in only 0.2% of routine cardiac angiographic studies conducted over a 10-year period. The clinical spectrums are various, asymtomatic, asymptomatic murmur, dyspnea on exertion, fatigue, and congestive heart failure. The right coronary artery (56%) and left coronary artery(36%) are mainly involved in the origin site of congenital coronary artery fistula. The draining site of fistula are right ventricle(39%), right atrium(33%), and pulmonary artery(20%) and so on. This 54 years-old woman had intermittent chest tightness and an abnormal mediastinal shadow on chest roentgenogram and chest C-T examination, which was diagnosed as a mediastinal mass such as teratoma. We performed the operation under left anterolateral thoracotomy for mass excision. However, we knew the mass had the pulsating arterial blood flow through a fine needle puncture of the mass and that it was attached to the left ventricle. We believed the excision of mass on beating heart would be very dangerous. Therefore, we closed the wound without excising the mass. After several days, we performed an echocardiography and coronary angiography, We knew it was cardiac tumor. Incidentally, the patient had a tortuous coronary fistula from the right coronary artery to pulmonary trunk. Using cardiopulmonary bypass with moderate systemic hypothermia, the mass was resected and the fistula was clipped with surgical clips. Pathology of the specimen was a giant coronary arterial aneurysm.

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Carbon and Nitrogen Inputs by Litterfall of Chamaecyparis obtusa Planted in Pine Wilt Disease-disturbed Forests (소나무재선충병 피해지에 식재된 편백의 낙엽·낙지에 의한 탄소 및 질소 유입량)

  • Kang, Hyeon Cheol;Baek, Gyeongwon;Choi, Byeonggil;Ha, Jiseok;Kim, Choonsig
    • Journal of Korean Society of Forest Science
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    • v.110 no.1
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    • pp.43-52
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    • 2021
  • In this study, carbon (C) and nitrogen (N) inputs by the litterfall of Japanese cypress (Chamaecyparis obtusa Endlicher) planted in pine wilt disease-disturbed forests were determined. The study sites were located in Sacheon-si, Gyeongsangnam-do. Eight plots under two regeneration sites (DR: four plots of C. obtusa planted under slightly disturbed Pinus thunbergii stands; CR: four plots of C. obtusa planted following the clear-cutting of severely disturbed pine stands) were established to collect litterfall from December 2018 to December 2019. The growth of diameter at breast height (DBH) was significantly higher in the CR treatment (12.10 cm) than that in the DR treatment (9.42 cm). C and N concentrations and the C/N ratio in C. obtusa leaf litter did not differ significantly between the two regeneration treatments, but the C/N ratio was significantly lower in the leaf litter collected in October (93) relative to that collected in December (143). The C concentration of litterfall components was significantly higher in C. obtusa leaf litter and in P. thunbergii needle litter than in broadleaved and miscellaneous litter, whereas the N concentration in broadleaved and miscellaneous litter was significantly higher than that in the leaf litter of C. obtusa and in branch litter. Thus, the C/N ratio was significantly higher in C. obtusa leaf litter and branch litter compared with that in miscellaneous and broadleaved litter. Respective C and N inputs by leaf litter were 773 kg C ha-1 yr-1 and 6.95 kg N ha-1 yr-1 for the CR treatments, and 78 kg C ha-1 yr-1 and 0.70 kg N ha-1 yr-1 for the DR treatment. Total C and N inputs were higher for the DR treatment (3,765 kg C ha-1 yr-1 and 47.6 kg N ha-1 yr-1, respectively) than for the CR treatment (1,290 kg C ha-1 yr-1 and 17.2 kg N ha-1 yr-1, respectively). These results indicate that, for C. obtusa, the DBH growth in the CR treatment was superior to that in the DR treatment, but the C and N inputs by litterfall were considerably reduced in CR treatments.

Computed Tomography-guided Localization with a Hook-wire Followed by Video-assisted Thoracic Surgery for Small Intrapulmonary and Ground Glass Opacity Lesions (폐실질 내에 위치한 소결질 및 간유리 병변에서 흉부컴퓨터단층촬영 유도하에 Hook Wire를 이용한 위치 선정 후 시행한 흉강경 폐절제술의 유용성)

  • Kang, Pil-Je;Kim, Yong-Hee;Park, Seung-Il;Kim, Dong-Kwan;Song, Jae-Woo;Do, Kyoung-Hyun
    • Journal of Chest Surgery
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    • v.42 no.5
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    • pp.624-629
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    • 2009
  • Background: Making the histologic diagnosis of small pulmonary nodules and ground glass opacity (GGO) lesions is difficult. CT-guided percutaneous needle biopsies often fail to provide enough specimen for making the diagnosis. Video-assisted thoracoscopic surgery (VATS) can be inefficient for treating non-palpable lesions. Preoperative localization of small intrapulmonary lesions provides a more obvious target to facilitate performing intraoperative. resection. We evaluated the efficacy of CT-guided localization with using a hook wire and this was followed by VATS for making the histologic diagnosis of small intrapulmonary nodules and GGO lesions. Material and Method: Eighteen patients (13 males) were included in this study from August 2005 to March 2008. 18 intrapulmonary lesions underwent preoperative localization by using a CT-guided a hook wire system prior to performing VATS resection for intrapulmonary lesions and GGO lesions. The clinical data such as the accuracy of localization, the rate of conversion-to-thoracotomy, the operation time, the postoperative complications and the histology of the pulmonary lesion were retrospectively collected. Result: Eighteen VATS resections were performed in 18 patients. Preoperative CT-guided localization with a hook-wire was successful in all the patients. Dislodgement of a hook wire was observed in one case. There was no conversion to thoracotomy, The median diameter of lesions was 8 mm (range: $3{\sim}15\;mm$). The median depth of the lesions from the pleural surfaces was 5.5 mm (range: $1{\sim}30\;mm$). The median interval between preoperative CT-guided with a hook-wire and VATS was 34.5 min (range: ($10{\sim}226$ min). The median operative time was 43.5.min (range: $26{\sim}83$ min). In two patients, clinically insignificant pneumothorax developed after CT-guided localization with a hook-wire and there were no other complications. Histological examinations confirmed 8 primary lung cancers, 3 cases of metastases, 3 cases of inflammation, 2 intrapulmonary lymph nodes and 2 other benign lesions. Conclusion: CT-guided localization with a hook-wire followed by VATS for treating small intrapulmonary nodules and GGO lesions provided a low conversion thoracotomy rate, a short operation time and few localization-related or postoperative complications. This procedure was efficient to confirm intrapulmonary lesions and GGO lesions.