• Asian Pacific Journal of Cancer Prevention
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• v.16 no.6
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• pp.2555-2559
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• 2015

Purpose: To investigate effects of the TESTIN (TES) gene on proliferation and migration of highly metastatic nasopharyngeal carcinoma cell line 5-8F and the related mechanisms. Materials and Methods: The target gene of human nasopharyngeal carcinoma cell line 5-8F was amplified by PCR and cloned into the empty plasmid pEGFP-N1 to construct a eukaryotic expression vector pEGFP-N1-TES. This was then transfected into 5-8F cells. MTT assays, flow cytometry and scratch wound tests were used to detect the proliferation and migration of transfected 5-8F cells. Results: A cell model with stable and high expression of TES gene was successfully established. MTT assays showed that the OD value of 5-8F/TES cells was markedly lower than that of 5-8F/GFP cells and 5-8F cells (p<0.05). Flow cytometry showed that the apoptosis rate of 5-8F/TES cells was prominently increased compared with 5-8F/GFP cells and 5-8F cells (p<0.05). In vitro scratch wound assays showed that, the width of the wound area of 5-8F/TES cells narrowed slightly, while the width of the wound area of 5-8F/ GFP cells and 5-8F cells narrowed sharply, suggesting that the TES overexpression could inhibit the migration ability. Conclusions: TES gene expression remarkably inhibits the proliferation of human nasopharyngeal carcinoma cell line 5-8F and reduces its migration in vitro. Thus, it may be a potential tumor suppressor gene for nasopharyngeal carcinoma.

• Journal of the Korean Society of Clothing and Textiles
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• v.31 no.1 s.160
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• pp.44-56
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• 2007

The aim of this study is to provide fundamental data on the development of dress shirts pattern appropriate for the body types of athletes. The research subjects are 257 athletes from wrestling, bodybuilding, weight lifting, Judo, canoe, rowing. In regards to the category used in the measurement of bust somatotype, there are 48 types directly measured, 4 types indirectly measured, 7 types calculated and 1 bodyweight of type, making it 60 categories in total. The bust somatotype of a sports athlete and general person were compared together and after examining the characteristics of the bust somatotype, the somatotype of sports athlete was divided according to drop. The results of the study are as follows: 1. Questionnaire Results of the questionnaire showed that 63.4% of the respondents chose dress shirt as the most uncomfortable upper garment for athletes. And as for the result of the most uncomfortable body part turned out to be 'the neck is tight'. 2. Somatotype Analysis Results of direct, indirect measurement and the average somatotype of 97 National standard physique were compared. The characteristics of somatotype of athletes with well-developed upper body are that they are taller and have longer upper body and arms than the general person. And also the width of the trunk is wider, the girth bigger and the waist measure relatively slimmer. Looking at sports by category, it we could see that wrestlers were the largest neck parameter and width. Bodybuilders were the largest body parts for most categories. Weight lifting and Judo athletes were the largest waist and buttock. Canoe and rowing athletes were the largest height and arm parts. Dividing the somatotype of athletes according to drop, 72.8% of the research group belonged to the body type that resembled the letter Y.

• Journal of Fashion Business
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• v.21 no.6
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• pp.66-76
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• 2017

This study used a virtual wearing system equipped with body shape data with a 3D scanner, based on a female basic bodice, to develop a modified Hanbok Jeogori with high fitness capabilities to provide basic data for the development of the modified Hanbok Jeogori pattern for the academic and industrial fields. In this study, the representative modified Hanbok design which most frequently appeared in broadcasting ads and on line was selected. The wearing test was conducted by six professionals, and three times wearing tests were implemented based on 17 evaluation items. The data for this study was processed statistically using SAS 9.0. We conducted, the F-test for significance verification, the Duncan-test for a post test, and a correlation analysis of Cronbach's alpha coefficient for a reliability test of dressing test results were implemented for each of the three tests. The pattern of the developed modified Hanbok Jeogori overcame the defects of the short length of the conventional modified hanbok, and could fix the length issue. The developed Hanbok pattern solved the overlapping problem of the shoulder, back neck point-sleeve length(Whajang), and armhole, displayed in a straight line from the Godae point of the previous modified Hanbok; it suggested the position of the Seop and neck line in the basic bodice. Based on this, the Seop width, Git form, Goreum and the width, length, and position of the string whose dimensions can differ in accordance with the trend can be applied in various forms.

• Journal of Korean Neurosurgical Society
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• v.64 no.2
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• pp.189-197
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• 2021

Objective : This study aims to investigate the relationship between aneurysm wall enhancement and clinical rupture risks based on the magnetic resonance vessel wall imaging (MR-VWI) quantitative methods. Methods : One hundred and eight patients with 127 unruptured aneurysms were prospectively enrolled from Feburary 2016 to October 2017. Aneurysms were divided into high risk (≥10) and intermediate-low risk group (<10) according to the PHASES (Population, Hypertension, Age, Size of aneurysm, Earlier SAH history from another aneurysm, Site of aneurysm) scores. Clinical risk factors, aneurysm morphology, and wall enhancement index (WEI) calculated using 3D MR-VWI were analyzed and compared. Results : In comparison of high-risk and intermediated-low risk groups, univariate analysis showed that neck width (4.5±3.3 mm vs. 3.4±1.7 mm, p=0.002), the presence of wall enhancement (100.0% vs. 62.9%, p<0.001), and WEI (1.6±0.6 vs. 0.8±0.8, p<0.001) were significantly associated with high rupture risk. Multivariate regression analysis revealed that WEI was the most important factor in predicting high rupture risk (odds ratio, 2.6; 95% confidence interval, 1.4-4.9; p=0.002). The receiver operating characteristic (ROC) curve analysis can efficiently differentiate higher risk aneurysms (area under the curve, 0.780; p<0.001) which have a reliable WEI cutoff value (1.04; sensitivity, 0.833; specificity, 0.67) predictive of high rupture risk. Conclusion : Aneurysms with higher rupture risk based on PHASES score demonstrate increased neck width, wall enhancement, and the enhancement intensity. Higher WEI in unruptured aneurysms has a predictive value for increased rupture risk.

• Fashion & Textile Research Journal
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• v.25 no.5
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• pp.593-602
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• 2023

This study aimed to facilitate the use of virtual technologies such as sewing, appearance, and material expression in 3D virtual wear programs. For product production and education, we expounded how to express the shoulder shape and silhouette of sleeve-expanded power shoulder jackets. Two designs of sleeve-expanded power shoulder jackets were selected, and virtual jackets were produced using a virtual avatar based on the body dimensions of female subjects in their 20s. The essential purpose of a 3D virtual power shoulder jacket is to express the shoulder angle rise and shoulder width, which are much wider than the avatar's shoulder. Therefore, the virtual pad values were adjusted for the collision and rendering of each thickness. In addition, the position and angle of the virtual pads were controlled through simulation. Appearance similarity was evaluated using photographic data and the virtual jackets. For the set-in sleeve virtual power shoulder jacket, the wrinkle expressions of the torso and sleeve were rated as moderate, and material expression was slightly insufficient. The similarity of some ease and width items of the torso was tightly expressed, and the overall appearance, positions of lines, and details of jackets were rated high, especially at the neck and sleeve shapes. In the case of the kimono virtual power shoulder jacket, the expressions of the torso wrinkles and buttons were slightly lower; however, the overall similarity, basic lines, ease, shoulder and neck details, and material expression of the virtual jackets were highly evaluated.

• Korean Journal of Human Ecology
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• v.23 no.6
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• pp.1191-1204
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• 2014

Even though a Han-bok, or traditional Korean costume, should be inherited since it is invaluable part of our culture, research on Han-bok is scarce. Since the development of a Jeogori pattern, the upper garment of Korean traditional clothes, is done mostly based on the chest size, the design does not completely consider on wearer's body shape. Moreover, unless made by an expert, trial and error is almost always necessary to improve the fit of the clothes. In this research, a Jeogori pattern was suggested that improves the fit based on the shape of the upper back(straight or bent) of a female in her late 20s who often wears a Han-bok and is comfortable when moving. Using a 3D virtual clothing system, the optimum pattern was selected based on the body shape. The final selection was made, and each subjects tried the garment on to evaluate the comfort when moving, along with its appearance, based on a seven point Likert scale. As a result, for a straight body shape, the optimum ease for the front bust width was 2.5cm, and that for the back bust width was 2.0cm. The optimum center back dart was 1.0cm. The optimum Geodae width was 7.6cm, and the optimum back Geodae point was 2.0cm. For the bent body shape, the optimum ease for the front and back bust was 2.0cm. The optimum Geodae width was 8.4cm, and the optimum back Geodae point was 1.5cm. Furthermore, if the Hwajang slope was set at half of the vertical distance between the laterals of the neck and shoulder, a fitted silhouette appeared, which is preferred nowadays. In the appearance evaluation, the final pattern designed in this research received higher scores than the original design(straight; p<.001, bent; p<.05). The results of the evaluation of the comfort when moving also showed higher scores for the final pattern that was designed.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.59 no.4
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• pp.823-830
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• 2010

This study was designed to examine the morphological measurement and characteristics of trabecullae based on femoral radiographic image for prediction of osteoporosis. Study subjects were 34 females (average age of 62.1 years) and 6 males (average age of 60.1 years), they were categorized into normal group and osteoporosis group in accordance with the T-score value. Measurement of the bone density of femoral bone was measured with DEXA(Dual Energy X-ray absorptiometry). ROI(Region of interests) was selected on femoral neck and trochanter. Characteristics of trabecullae was analyzed by using the skeletonization analysis of trabecular image. Morphological measurement was analyzed through femoral radiographic image in order to examine the correlation with osteoporosis. The result demonstrated statistically significant correlation between neck cortical thickness, shaft width, shaft cortical thickness, periphery, mean gray level and trabeculae area with BMD average (T-score) of femoral part. The results show that morphological measurement and characteristics of trabecullae based on femoral radiographic images for osteoporosis prediction could be effective.

• Journal of Fashion Business
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• v.7 no.2
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• pp.1-14
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• 2003

This study were to grasp the present situation of the pet wear market and the problem of pet wear, and to develop the pet wear pattern which agrees well to dog's shape and movements. We carried out survey research to analyze the actual pet wear market condition for a dog-lover, and movement analysis and sensory test to develop a pattern for Maltese which was the favorite dog among Korean. For data analysis, ANOVA with duncan test, T-test were conducted using SPSS statistic program(ver. 10.0). The results are as follows: 1. The results of the survey research, 75% of dog-lover had a pet wear and favorite was T-shirts. The problems of wearing T-shirts were 'too tight seam sleeve and bodice(front legs hole)', 'the clothes easily hang down' and 'easily taken off due to large neck size'. 2. The ease amount of the developed pattern was given according to the results of dog's shape and movement analysis, and the results of sensory test, there is a significant difference in the following items: depth of front neck line, front chest${\to}$abdomen curve, ease amount of sleeve, comfort level of leg parts. 3. The size of each parts of the developed pattern in this study were as follows : neck girth 27.0cm, body girth 40.0cm, back length 26.0cm, front leg girth 23.0cm, sleeve length 20.7cm, sleeve width 14.4cm. But, there exists some limits to generalize these results since dog's body size and shapes are various according to dog species. Therefore, further studies are needed to develop each pet wear pattern for each dog species.

• The Journal of Korean Society for Radiation Therapy
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• v.11 no.1
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• pp.73-78
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• 1999

In general, the patients of the head and neck cancer are treated with 4MV photon beam up to prescribed dose, but spinal cord should be excluded in the treatment field. When its absorbed dose is limited at the tolerance dose. In case of the patients who has the positive posterior neck nodes need a boost electron beam treatment to the prescribed dose. In that case, the anatomical structure of the neck and the physical structure of the standard electron cone interrupt to allow proper access to the disease site. Therefore, we extended treatment SSD for the remove of the those hindrances. In this study, we evaluated the dosimetric variation of the standard electron cone for the extended SSD, from 100cm to 120cm, 5 cm increment, and compare to the custom-made electron cone. As a result, the $\%$ depth dose, the point of maximum dose and the range of maximum were changed within the $2\%$. The penumbra width was increased from 1.0cm to 2.0cm. However, the dosimetric characteristics of the custom-made electron cone was very similar to that of the 100cm SSD standard electron cone and due to its characteristic of physical structure, patients didn't need re-positioning after photon beam treatment, therefore accurate treatment was possible, we conclude that the custom-made electron cone was very useful for the clinical practice.

• Korean Journal of Bronchoesophagology
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• v.12 no.2
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• pp.19-25
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• 2006

There have been numerous modalities to recover blink function of orbicularis oculi muscle in patients with facial paralysis. However, there is still no optimal method for reanimation of eyelid. In this study, we tried to recover blink function of paralyzed rabbit's eyelid with the ion polymer metal composite (IPMC) which is one of the electroactive polymers that is spotlighted as artificial muscle. We manufactured IPMC by plating the platinum over perfluorosulphonic acid polymer ($Nafion^{(R)}$). IPMC was coated by Norland optical adhesive for the purpose of insulation and keeping it from dry. IPMC modifications by roughening the surface of Nafion, repetitive plating (maximum 4 times) with platinum, and lengthening the width of IPMC were done. The facial paralysis was induced in the rabbit by sectioning of facial nerve at the main trunk. After minimum period of 4 weeks, IPMC was inserted in the paralyzed rabbit's eyelid. By modification, the force generated by IPMC was enhanced. Restoration of blink function in paralyzed rabbit was achieved on electrical stimulation of the IPMC by 5 voltage direct current. IPMC can be promising option for facial reanimation, but further studies are needed to enhance the efficiency of IPMC.