• Spatial Information Research
• /
• v.7 no.2
• /
• pp.191-207
• /
• 1999

Data and information necessary for solving the spatial decision making problems are imperfect or inaccurate and most are described by natural language. In order to process these arts of information by the computer, the obscure linguistic value need to be described quantitatively to let and computer understand natural language used by humans. For this , the fuzzy set theory and the fuzzy logic are used representative methodology. So this paper describes the construction of the language model by the natural language that user easily can understand and the logical concepts and construction process for building the fuzzy inference mechanism. It makes possible to solve the space related decision making problems intellectually through structuring and inference used by the computer, in case of the evaluation concern or decision making problems are described inaccurate, based on the inaccurate or indistinct data and information.

• Biomolecules & Therapeutics
• /
• v.29 no.6
• /
• pp.571-581
• /
• 2021

Towards the end of 2019, an atypical acute respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified in Wuhan, China and subsequently named Coronavirus disease 2019 (COVID-19). The rapid dissemination of COVID-19 has provoked a global crisis in public health. COVID-19 has been reported to cause sepsis, severe infections in the respiratory tract, multiple organ failure, and pulmonary fibrosis, all of which might induce mortality. Although several vaccines for COVID-19 are currently being administered worldwide, the COVID-19 pandemic is not yet effectively under control. Therefore, novel therapeutic agents to eradicate the cause of the disease and/or manage the clinical symptoms of COVID-19 should be developed to effectively regulate the current pandemic. In this review, we discuss the possibility of managing the clinical symptoms of COVID-19 using natural products derived from medicinal plants used for controlling pulmonary inflammatory diseases in folk medicine. Diverse natural products have been reported to exert potential antiviral effects in vitro by affecting viral replication, entry into host cells, assembly in host cells, and release. However, the in vivo antiviral effects and clinical antiviral efficacies of these natural products against SARS-CoV-2 have not been successfully proven to date. Thus, these properties need to be elucidated through further investigations, including randomized clinical trials, in order to develop optimal and ideal therapeutic candidates for COVID-19.

• Natural Product Sciences
• /
• v.25 no.3
• /
• pp.248-254
• /
• 2019

In the present study, we investigated whether quercitrin, quercetin and afzelin derived from Houttuynia cordata affect the production and gene expression of MUC5AC mucin from airway epithelial cells. Confluent NCI-H292 cells were pretreated with quercitrin, quercetin or afzelin for 30 min and then stimulated with epidermal growth factor (EGF) or phorbol 12-myristate 13-acetate (PMA) for 24 h. The MUC5AC mucin gene expression and production were measured by RT-PCR and ELISA, respectively. The results were as follows: (1) Quercitrin, quercetin and afzelin inhibited EGF- and PMA-induced MUC5AC mucin production from NCI-H292 cells; (2) The three natural products also decreased EGF- and PMA-induced MUC5AC mucin gene expression in NCI-H292 cells. These results suggest that quercitrin, quercetin and afzelin showed the regulatory effect on the steps of gene expression and production of mucin, by directly acting on airway epithelial cells.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
• /
• v.7 no.10
• /
• pp.703-711
• /
• 2017

Today, men's appearance is an important part of the global fashion industry, including Korea, with such fashion concepts as the Metrosexual and Ubersexual. Domestic and overseas beauty and cosmetics related organizations are using this phenomenon for marketing and researching to improve the function of cosmetics. The purpose of this study was to investigate the effect of Prunus persica L. Batsch leaf extract on the skin condition after clinical application to male subjects with oily skin to determine the possibility of functional cosmetics utilizing this extract. The cleansing bars were prepared by the MP method and the cleansing packs were prepared using natural ingredients. After 8 weeks of application, moisture, oil, erythema, melanin, pH, elasticity and tactile sensation were measured using MPA5. The results showed that there was a statistically significant difference in T-zone moisture and T-zone oil after using the natural cleansing bar, but there was no significant difference between the two groups for other items. However, the statistically significant changes were found in the individual skin condition change items of the subjects in each group, and it was judged that the two kinds of formulations could be used at the same time to have a higher skin improvement effect. Thus, Prunus persica L. Batsch leaf extract demonstrates potential to be used as a functional cosmetics item.

• Korean Journal of Agricultural Science
• /
• v.51 no.3
• /
• pp.341-350
• /
• 2024

According to various negative effects of antibiotic growth promoters, the effects of nature-derived alternatives to antibiotic growth promoters are mainly investigated in livestock industry these days. The effects of nature-derived alternatives to antibiotic growth promoters are mainly investigated in livestock industry these days. This study was conducted to estimate the efficiency of natural-derived alternatives to antimicrobial and antioxidant such as oregano oil (OGO), sulfide type antimicrobial peptides derived from Bacillus or Yeast (SAPBY), antimicrobial peptides derived from yeast (APY). The lactic acid bacteria growth effects were found to be minimal. The antibacterial activity of SAPBY was minimal, but OGO and APY showed antibacterial activity against Escherichia coli and Salmonella Typhimurium, and APY also showed antibacterial activity against Staphylococcus. Antioxidant effects were observed in all SAPBY, OGO, and APY, and when comparing the radical scavenging rate at 10 mg·mL^-1 for each sample, OGO showed the highest at 84.9%, followed by SAPBY at 48.7%. Therefore, the substances that can be used as natural antibiotics are SAPBY, APY, and OGO. It is believed that adding these substances to feed and feeding them to livestock will greatly contribute to improving the health of livestock and the productivity of safe livestock products. In further, research focused on various nature-derived alternatives to antibiotic growth promoter in livestock industry is needed.

• Journal of the Korean Society for Industrial and Applied Mathematics
• /
• v.8 no.2
• /
• pp.1-5
• /
• 2004

A multiplicative plane partition is a two-dimensional array of positive integers larger than 1 that are nonincreasing both from left to right and top to bottom and whose multiple is a given number n. For a natural number n, let $f_2(n)$ be the number of multiplicative plane partitions of n. In this paper, we prove $f_2(n)\;{\leq}\;n^2$ and a table of them up to $10^5$ is provided.

• Journal of the Korean Data and Information Science Society
• /
• v.21 no.6
• /
• pp.1353-1359
• /
• 2010

Basic objective in cluster analysis is to discover natural groupings of items. In general, clustering is conducted based on some similarity (or dissimilarity) matrix or the original input data. Various measures of similarities between objects are developed. In this paper, we consider a clustering of huge categorical real data set which shows the aspects of time-location-activity of Korean people. Some useful similarity measure for the data set, are developed and adopted for the categorical variables. Hierarchical and nonhierarchical clustering method are applied for the considered data set which is huge and consists of many categorical variables.

• Communications of the Korean Mathematical Society
• /
• v.34 no.2
• /
• pp.507-522
• /
• 2019

The main aim of this present paper is to present a new extension of the fractional derivative operator by using the extension of beta function recently defined by Shadab et al. [19]. Moreover, we establish some results related to the newly defined modified fractional derivative operator such as Mellin transform and relations to extended hypergeometric and Appell's function via generating functions.

• Journal of the Korean Home Economics Association
• /
• v.45 no.7
• /
• pp.105-117
• /
• 2007

The purposes of this study were 1) to classify adult consumers according to their desired clothing benefits on natural-dyed clothes, 2) to identify the differences of life-style among the classified groups, and 3) to determine the interest in Korean traditional culture, interest in dyeing, and demographics among the groups. The survey subjects were 283 adults. The data were analyzed utilizing factor analysis, cluster analysis, $x^2$-test, one-way ANOVA, Duncan test and multiple regression analysis. Based on the 6 dimensions of clothing benefits that were identified by factor analysis, adult consumers were classified into three clusters: eco-friendly oriented group showing the highest scores in environment conservation and comfort in clothing benefits, individuality-oriented group showing the highest scores in individuality and quality, and indifference group showing lower scores in all of the desired clothing benefits. The eco-friendly group showed the highest scores in attitude toward Korean traditional culture, and tended to have the most interest in natural and traditional methods of dyeing. The group members appeared to have passive life-styles, be older and married, and have a higher income than the other groups. The more positive attitude they had in Korean traditional culture, the higher was the purchase intention shown in the eco-friendly group. The individuality-oriented group showed active life-styles. This group tended to be younger than the other group. The more affirmative attitude in Korean traditional culture and the greater interest in the natural dyeing, the higher was the consumers' purchase intention of natural dyeing apparels. The indifference group tended to be younger, unmarried, and have a lower income. This group was not interested in natural dyeing apparels. The study findings demonstrated that consumers with different clothing benefits sought have different buying patterns on natural dyeing apparels. Finally the marketing implications are discussed.

• Clinical and Experimental Reproductive Medicine
• /
• v.27 no.4
• /
• pp.381-385
• /
• 2000

Objective: To verify the effect of two forms (growth factor and growthfactor-reduced) of solubilized Matrigel on the development in mouse preimplantation embryos. Methods: Late 2-cell stage eggs were cultured through the blastocyst stage in the presence of GF- or GFR-Matrigel (0.5%, v/v). Morphological development, cell number and % apoptotic nuclei of blastocyst were measured by Roecst staining and TUNEL of nuclei. Results: Morphological development, number of cells per embryo was significantly increased in the presence of GF- or GFR-Matrigel. Culture of the embryos in the GF-Matrigel gave the best result. Conclusion: Low concentration of solubilized Matrigel improved development of mouse embryos regardless of growth factor content of the Matrigel. Growth factors and extracellular matrix protein included in the Matrigel synergistically potentiated the development of mouse embryos.