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An Experimental Study of Effect on ECV 304 Cells, Platelet Rich Plasma and Rats treated with L-NAME by Ondamtang extract (온담탕이 고혈압 백서와 인간유래 혈관내피세포주(ECV 304)에 미치는 영향)

  • Baek Il-Sung;Park Chang-Gook;Lee So-Yeon;Yoon Hyeon-Deok;Sin Wo-Chul;Park Chi-Sang
    • Herbal Formula Science
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    • v.12 no.2
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    • pp.175-202
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    • 2004
  • Nitric oxide(NO) play an important role in normal and pathophysiological cells including as a messenger molecule, neurotransmitter, microbiocidal agent, or dilator of blood vessels and artheriosclerosis, hypertension, myocardial infarction, respectively. To investigate that Ondamtang in the potential contribution of the levels of nitric oxide generated by endothelial nitric oxide synthase (eNOS) and the mechanisms of protection against L-NAME, human ECV304 cells, which normally do not express eNOS, were expressed by L-NAME. L-NAME stimulated rat or cells were found to be resistant to injury and delayed death following the Ondam-tang. Inhibition of nitric oxide synthesis abolished the protective effect against L-NAME, thrombin and collagen exposure. Interestingly, such effects have bee observed during stimulation with agents such as KCl on L-NAME mediate rats, were damaged by the NOS inhibitor NG-nitro-L-arginine methyl ester (L-NAME). Cardiovascular diseases is one of the blood vessels and renin-angiotensin system dynfunction. So we studied on herbal medicine that have a relation of vessels endothelium necrosis. In Oriental Medicine, Ondam-tang has been used for disease in relation to cardiovascular system. We studied on the protection and inhibitory effects of cardiovascular diseases in L-NAME induced rat or ECV304 cell lines through the Cell morphological pattern, Tunel assay, LDH activity, heart rate, blood pressure and immunohistochemistric analysis by Ondam-tang. As the result of this study, In group, the anti-apoptosis and necrosis in the cardiovascular system have a potential capacity for prevented, protected and treating the diseases of cardiovascular system, against the necrosis of rat and ECV304 cells with eNOS and calpain expression by L-NAME is promoted.

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The Effect of Adult's Name Attractiveness on Self-efficiency and Emotionality (성인의 이름매력도가 자기효능감과 정서에 미치는 영향)

  • Kim, Ki-Seung;Ham, Hae-Soo;Na, Hyeok-Jin
    • Industry Promotion Research
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    • v.5 no.1
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    • pp.99-106
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    • 2020
  • The purpose of this study was to analyze the effects of name attractiveness on self-efficacy and emotional awareness in adult men and women. The subjects of this study were 300 males and females in their 10s and 30s living in the metropolitan area. However, 250 copies, excluding missing questionnaires during the collection process and incomplete questionnaires, were used for the analysis. As a result of analyzing the difference in name attractiveness according to factors, the lower the age group and the lower the academic level, the more dissatisfied they were with their names. Besides, the regression analysis conducted to verify the effect of name attractiveness on self-efficacy showed that the model's fitness was R2=.382 and the model's explanatory power was somewhat inferior, but β=.322, t-value 9.276, p<.001 were shown to be statistically significant, so name attraction directly affects self-efficacy. And the results of the regression analysis conducted to verify the effect of name attractiveness on emotionality turned out to be R2=.412. The regression analysis, which controls demographic variables such as gender, age, and academic level, was statistically significant as β=.326, t-value 6.408, p<.001. In other words, the name attractiveness affects emotional awareness. There is no empirical study that the name attractiveness can improve happiness or the quality of life, but it seems often among athletes that names are enhanced by the past.

Nitric Oxide/cGMP-Independent Vasorelaxation Enhanced by L-Arginine (L-Arginine의 산화질소생성과 무관한 혈관이완효과)

  • 문승호;이종은;유광재;오봉석;이동준
    • Journal of Chest Surgery
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    • v.31 no.2
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    • pp.102-107
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    • 1998
  • It has not been clear whether L-arginine plays solely a role contributing to vascular nitric oxide (NO) synthesis. To investigate the mechanisms by which L-arginine induces vasorelaxation, effects of L-arginine on the isometric tension, and tissue NOx and cyclic guanosine monophosphate(cGMP) contents were examined in the isolated rat thoracic aorta. L-Arginine induced a dose-dependent relaxation of aortic rings only with intact endothelium only. The vasorelaxation response to low concentrations of L-arginine was abolished by the pretreatment with NG-nitro-L-arginine methyl ester(L-NAME, 10-4 mol/L), whereas the relaxation caused by higher concentrations L-arginine(10-5-10-3 mol/L) was maintained and even more pronounced in the presence of L-NAME. L-Arginine did not affect the vascular tension precontracted with KCl. The vascular tissue contents of NOx/cGMP were not significantly affected by L-arginine, while they were decreased by L-NAME. L-Arginine could not completely recover the NOx/cGMP decreased by L-NAME. Methylene blue only partially antagonized the relaxation response to L-arginine. Indomethacin did not affect the L-arginine-induced vasorelaxation, whereas ouabain markedly attenuated the relaxation. It is suggested that L-arginine induces vasorelaxation not only through its contribution to NO synthesis, but also through enhancing another endothelium-dependent mechanism which is NO/cGMP-independent and cyclooxygenase- independent.

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Design and Implementation of DNS Name Autoconfiguration for Internet of Things Devices (사물인터넷 디바이스를 위한 DNS 네임 자동설정의 설계 및 구현)

  • Lee, Sejun;Jeong, Jaehoon
    • Journal of KIISE
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    • v.42 no.11
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    • pp.1441-1451
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    • 2015
  • As one of the most spotlighted research areas, these days, the Internet of Things (IoT) aims to provide users with various services through many devices. Since there exist so many devices in IoT environments, it is inefficient to manually configure the domain name system (DNS) names of such devices. Thus, for IPv6-based IoT environments, this paper proposes a scheme called the DNS Name Autoconfiguration (DNSNA) that autoconfigures an IoT device's DNS name and manages it. In the procedure for generating and registering an IoT device's DNS name, the standard protocols of the Internet Engineering Task Force (IETF) are used. Since the proposed scheme resolves an IoT device's DNS name into an IPv6 address in unicast through a DNS server, it generates less traffic than multicast-based mDNS (Multicast DNS) which is a legacy DNS application for the DNS name service in the smart home. Thus, the proposed scheme is more appropriate in multi-hop IoT networks than mDNS. This paper explains the design of the proposed scheme and its service scenarios, such as smart home and smart road. It also explains the implementation and testing of the proposed scheme in the smart grid.

An Experimental Study of Effect on ECV 304 Cells, Platelet Rich Plasma and Rats treated with L-NAME by Boonsimgieum extract (분심기음(分心氣飮)이 고혈압 백서와 인간유래 혈관내피세포주(ECV 304)에 미치는 영향에 대한 연구)

  • Jeon, Yeon-Yi;Park, Chang-Gook;Lee, So-Yeon;Yoon, Hyeon-Deok;Shin, Wo-Cheol;Park, Chi-Sang
    • The Journal of Internal Korean Medicine
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    • v.26 no.1
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    • pp.182-198
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    • 2005
  • Object : This study was designed to research whether the protection and inhibitory effects of cardiovascular diseases in L-NAME induced rat or ECV 304 cell lines through the Cell morphological pattern, Tunel assay, LDH activity, heart rate, blood pressure and immunohistochemistric analysis by Boonsimgieum water extract Methods : Nitric oxide(NO) play an important role in normal and pathophysiological cells including as a messenger molecule, neurotransmitter, microbiocidal agent, or dilator of blood vessels and artheriosclerosis, hypertension, myocardial infarction, respectively. Endothelial cell products can modulate the magnitude of a response to a vasoconstrictor, as evinced by the greater constriction after endothelium removal or NO synthesis blockade. To investigate that Boonsimgieum in the potential contribution of the levels of nitric oxide generated by endothelial nitric oxide synthase (eNOS) and the mechanisms of protection against NG-nitro-L-arginine methyl ester (L-NAME), human ECV 304 cells, which normally do not express eNOS, were expressed by L-NAME. L-NAME stimulated rat or cells were found to be resistant to injury and delayed death following the Boonsimgieum. Inhibition of nitric oxide synthesis abolished the protective effect against L-NAME, thrombin and collagen exposure. Interestingly, such effects have been observed during stimulation with agents such as phenylephrine and KCl on L-NAME mediate rats, were damaged by the NOS inhibitor L-NAME. Result : As the result of this study, In group, the anti-apoptosis and necrosis in the cardiovascular system have a potential capacity for prevented, protected and treating the diseases of cardiovascular system, against the necrosis of rat and ECV 304 cells with Caspase 3 and calpain expression by L-NAME is promoted. Conclusion : these results demonstrate neuroprotective and memory enhancing effects of ZIBU, suggesting its beneficial actions for the treatment of AD.

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A Study on the Development of Guidelines for Place Name Authority Standardization (지명 전거 표준화를 위한 지명 전거데이터 기술 지침 개발에 관한 연구)

  • Ji-won Baek;Sungsook Lee
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.35 no.1
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    • pp.169-192
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    • 2024
  • This study was conducted with the aim of providing a foundation for high-quality national place name authority data by developing Korean-specific guidelines for place name authority data in response to the need for systematic construction and standardization of authority databases. To this end, a survey of domestic and international trends and cases related to place name authority data was conducted, and the rules and guidelines of each country for establishing place name authority data were analyzed. Based on these surveys and rule analyses, the scope of concepts and terminology required to build a place name authority database were defined and the direction for the development of place name authority data guidelines was set. The analysis also determined the scope and framework of the guidelines, and how they should be referenced to existing rules. The structure of the guidelines proposed in this study is based on the original RDA and NCR. Based on the implications derived from the analysis process, the guidelines were organized and presented in terms of scope of construction, selection and recording of preferred place names, recording of variant place names, and attributes of place names to propose a technical guideline for place name authority data that fits the Korean situation. Future discussions were revealed accordingly.

Server based Mobile Multi-lingual Recognition System of Name-card (서버기반 모바일 다국어 명함인식 시스템)

  • Jang, Dong-Hyeub;Lee, Jae-Hong;Kim, Seong-Hak
    • KIPS Transactions on Software and Data Engineering
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    • v.3 no.4
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    • pp.155-162
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    • 2014
  • In this study, we developed a server-based mobile multi-lingual name-card recognition system which utilizes smartphone only as a terminal for capturing images of name-card and displaying results of recognition, running server as a recognizer of characters. For efficient processing and transmission of captured images, we corrected the distorted images, removed noises from them, and defined the socket-based protocol for wireless transmission of images between smartphone and the recognizer on server. Various tests for name-cards of five language types show increased recognition rate and speed of the developed system against conventional smartphone-based recognizers.

A Study on the Etymology of the Place Names 'Myeongryang' and 'Noryang' (지명 '명량(鳴梁)'과 '노량(露梁)'의 어원 고찰)

  • Kim, Jin-Sik
    • Lingua Humanitatis
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    • v.8
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    • pp.241-263
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    • 2006
  • Place names are generally composed of first half and second half, whether the originality of those names comes from Korean or Chinese. The first half, modifying the second half, represents the naming flexibility of the name, while the second half of the name points out its directive object, which refers to a branch of the name. For example, 'Myeong' in 'Myeongryang' and 'No' in 'Noryang' represent their naming flexibility while 'Ryang', constituting the second half, points out the name's directive object. The purpose of this study was to investigate the etymology of place names, 'Myeongryang' and 'Noryang', by figuring out the meanings of those two elements. In order to search for the meaning of the second half, 'Ryang', other examples presented in the related literature have been examined. The finding indicated that 'Ryang' means 'dol', or 'do', which refers to 'moon(door)'. Furthermore, it is found out that the meaning of 'Ryang' has been transferred from 'dol' or 'do' to 'moon(door)', furthermore, to the straits. Upon looking into the origins of those names on the field, it is interpreted that 'Myeong Ryang' has been meant as a door in which huge and rough waves cry out, and 'No Ryang' has been meant as a door in which huge and rough waves rise up.

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Language and History (언어와 역사)

  • 도수희
    • Lingua Humanitatis
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    • v.2 no.1
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    • pp.75-92
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    • 2002
  • The historical facts usually remain in the linguistic records. The name of a place has been considered most useful among the records. The name of a place contains lots of information which help us analyzing and explaining the historical problems. The main purpose of this thesis is to account for the relation between language and history based on the data of the name of a place with the property just mentioned above. Firstly I will estimate the territory of the former period of Paek-Che (18B.C.~475A.D.) on the basis of the distribution of the old name of a place and show that the presumed shape of the territory could prove the fact that the unification of Shilla is 'the unification of two nations' but not 'the unification of three nations' Secondly the distribution of the old name of a place can bring light on the interrelation between Paek-Che language and Kara language and help us understand the relation of neighboring countries between two nations. Thirdly we can discuss the relation between the language of the former period of Paek-Che and of the old period of Japan: that is, how the language of Paek-Che came in the Japanese language. Also, the history of cultural domination between Paek-Che and Japan could be clarified if we can prove the linguistic similarity of two nations either to be genealogical relation or to be borrowing one.

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The Figurative Structure of 'One Night, Counting the Stars" (윤동주의 시 "별헤는 밤"의 비유구조)

  • 유재천
    • Lingua Humanitatis
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    • v.1 no.1
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    • pp.185-194
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    • 2001
  • In this paper, I propose that the figurative structure of Tongjoo Yoon′s "One Night, Counting the Stars" reflects the poet′s anguish over the colonial reality of Korea in the later stages of the Japanese occupation, especially regarding the forced adoption of Japanese names in 1939. The poet Yoon himself registered at Yonhi College with an adopted Japanese name. In the second half of the poem, the speaker alludes to this historical fact when he confesses that "On a hill lit by myriads of stars / I spelled my name / And covered it over with dirt," and that he "laments (his) shameful name." In the simile of the last stanza, the speaker continues to allude to the "buried" name: "But past winter, come spring to my star, / As green grass sprouts on a grave mound, / So will it spread with pride / On the hill where my name is buried." The longing and the yearning, expressed so simply and in child-like manner in the first half of the poem, become in the second half an urgent need for something that should have been but cannot be, and yet will be in the future-for a world that should be, now lost but to be regained. The poem contains the poet′s earnest belief that the inherited Korean names that were then so shamefully taken away will one day be recovered. It is almost impossible to find any other work written in Korean (despite the most suppressive measures against the use of the Korean language) that also alludes to the adoption of Japanese names. In this respect, "One Night, Counting the Stars" has a unique value in the history of modem Korean literature.

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