• 제목/요약/키워드: must cell

검색결과 677건 처리시간 0.029초

Oven형 건조 및 열풍건조에 대한 전도성 잉크의 건조 특성에 관한 연구 (A study on the drying characteristics of conductive ink by oven drying system and the hot-air drying system)

  • 홍승찬;이재효;정길용
    • 대한설비공학회:학술대회논문집
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    • 대한설비공학회 2009년도 하계학술발표대회 논문집
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    • pp.1429-1434
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    • 2009
  • Recently electronic circuit pattern printing technologies like antennas of RFID process are paid attention. oven drying system is being used since drying and curing time of RFID Tag Gravure printing normally takes from 5 minutes and up to 30 minutes long. In this case the parental material which is of a sheet shape is possible, however, for a massive and a continuous production drying and curing process must be done on-line. This research compared and analyzed the an oven type drying device and a traditional hot-air drying device. Considering the experiment result, the cell depth that shows low resistivity, which doesn't consider the pattern difference, is $31{\sim}33{\mu}m$. Also, oven drying system showed some resistivity after around 120 seconds of drying time, and showed much better performance in minimum resistivity compared to the hot-air drying system.

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Involvement of PI3K and MMP1 in PDGF-induced Migration of Human Adipose-derived Stem Cells

  • Lim, Yoonhwa;Lee, Minji;Jeong, Hyeju;Kim, Haekwon
    • 한국발생생물학회지:발생과생식
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    • 제21권2호
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    • pp.167-180
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    • 2017
  • Human adult stem cells have widely been examined for their clinical application including their wound healing effect in vivo. To function as therapeutic cells, however, cells must represent the ability of directed migration in response to signals. This study aimed to investigate the mechanism of platelet-derived growth factor (PDGF)-induced migration of the human abdominal adipose-derived stem cells (hADSCs) in vitro. A general matrix metalloproteinase (MMP) inhibitor or a MMP2 inhibitor significantly inhibited the PDGF-induced migration. PDGF treatment exhibited greater mRNA level and denser protein level of MMP1. The conditioned medium of PDGF-treated cells showed a caseinolytic activity of MMP1. Transfection of cells with siRNA against MMP1 significantly inhibited MMP1 expression, its caseinolytic activity, and cell migration following PDGF treatment. Phosphatidylinositol 3-kinase (PI3K) inhibitor reduced the migration by about 50% without affecting ERK and MLC proteins. Rho-associated protein kinase inhibitor mostly abolished the migration and MLC proteins. The results suggest that PDGF might signal hADSCs through PI3K, and MMP1 activity could play an important role in this PDGF-induced migration in vitro.

The Pentose Phosphate Pathway as a Potential Target for Cancer Therapy

  • Cho, Eunae Sandra;Cha, Yong Hoon;Kim, Hyun Sil;Kim, Nam Hee;Yook, Jong In
    • Biomolecules & Therapeutics
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    • 제26권1호
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    • pp.29-38
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    • 2018
  • During cancer progression, cancer cells are repeatedly exposed to metabolic stress conditions in a resource-limited environment which they must escape. Increasing evidence indicates the importance of nicotinamide adenine dinucleotide phosphate (NADPH) homeostasis in the survival of cancer cells under metabolic stress conditions, such as metabolic resource limitation and therapeutic intervention. NADPH is essential for scavenging of reactive oxygen species (ROS) mainly derived from oxidative phosphorylation required for ATP generation. Thus, metabolic reprogramming of NADPH homeostasis is an important step in cancer progression as well as in combinational therapeutic approaches. In mammalian, the pentose phosphate pathway (PPP) and one-carbon metabolism are major sources of NADPH production. In this review, we focus on the importance of glucose flux control towards PPP regulated by oncogenic pathways and the potential therein for metabolic targeting as a cancer therapy. We also summarize the role of Snail (Snai1), an important regulator of the epithelial mesenchymal transition (EMT), in controlling glucose flux towards PPP and thus potentiating cancer cell survival under oxidative and metabolic stress.

염료감응형 태양전지의 염료 흡착 온도의 영향에 관한 연구 (The effect of dye coloring temperature on the dye-sensitized solar cells)

  • 이경준;김정훈;홍지태;서현웅;손민규;김희제
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2008년도 제39회 하계학술대회
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    • pp.1279-1280
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    • 2008
  • A serious problem of the 21st century is the supply of energy resources. Reserves of fossil fuels are facing depletion: renewable energy resources must be developed in this era. Dye sensitized solar cells(DSC) have been very economical and easy method to convert solar energy to electricity. DSC can reach low costs in future outdoor power applications. However, to commercialize the DSC, there are still many shortages to overcome. When the DSC is commercialized in the near future, the productivity is an important factor. In the process of soaking in a dye, it usually takes 12${\sim}$24 hours. In this study, we varied the dye coloring temperature from 0$^{\circ}C$ to 60$^{\circ}C$. At the temperature of 40$^{\circ}C$, DSC cell showed the best performance. We also conducted the time variant experiment to reduce the manufacturing time. Counter electrode surface of DSC is deposited by RF magnetron sputtering under the conditions of Ar $2.8{\times}10^{-3}torr$, RF power of 120W and substrate temperature of 100$^{\circ}C$.

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주파수차법을 이용한 남극크릴(Euphausia superba)의 종 식별에 관한 연구 (Species Identification of Antarctic Krill Euphausia superba Using the 2-frequency Difference Method)

  • 최석관;한인우;황두진;김태호;안두해;이경훈
    • 한국수산과학회지
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    • 제50권6호
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    • pp.788-798
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    • 2017
  • Antarctic krill Euphausia superba are important components of the Antarctic marine ecosystem both economically and ecologically; to manage this species effectively, their distribution and abundance must be understood. Using the Kwang Ja-Ho (3,012 tonnage), a commercial fishing vessel, we conducted acoustic surveys during April 13-24, 2016, to estimate the distribution and population size of krill around the South Shetland Islands of the Antarctic Continent, We used acoustic techniques based on the dB-difference, a method used mainly to classify of marine species. We found that Antarctic krill were present in numbers over 99% at six survey stations, with the exception of Station 3, where we only found Electrona carlsbergi. There was no difference in cell size due to frequency differences, but echo signals differed between species: 4.7-12.0 dB for Antarctic krill, and -4.1~0 dB for Electrona carlsbergi.

Targeted Nanomedicine that Interacts with Host Biology

  • 주진명
    • 한국표면공학회:학술대회논문집
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    • 한국표면공학회 2017년도 춘계학술대회 논문집
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    • pp.81-81
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    • 2017
  • Nanotechnology is of great importance to molecular biology and medicine because life processes are maintained by the action of a series of molecular nanomachines in the cell machinery. Recent advances in nanoscale materials that possess emergent physical properties and molecular organization hold great promise to impact human health in the diagnostic and therapeutic arenas. In order to be effective, nanomaterials need to navigate the host biology and traffic to relevant biological structures, such as diseased or pathogenic cells. Moreover, nanoparticles intended for human administration must be designed to interact with, and ideally leverage, a living host environment. Inspired by nature, we use peptides to transfer biological trafficking properties to synthetic nanoparticles to achieve targeted delivery of payloads. In this talk, development of nanoscale materials will be presented with a particular focus on applications to three outstanding health problems: bacterial infection, cancer detection, and traumatic brain injury. A biodegradable nanoparticle carrying a peptide toxin trafficked to the bacterial surface has antimicrobial activity in a pneumonia model. Trafficking of a tumor-homing nanoprobes sensitively detects cancer via a high-contrast time-gated imaging system. A neuron-targeted nanoparticle carrying siRNA traffics to neuronal populations and silences genes in a model of traumatic brain injury. Unique combinations of material properties that can be achieved with nanomaterials provide new opportunities in translational nanomedicine. This framework for constructing nanomaterials that leverage bio-inspired molecules to traffic diagnostic and therapeutic payloads can contribute on better understanding of living systems to solve problems in human health.

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Morphogenesis of the Eye of Brown Croaker (Miichthys miiuy)

  • Park, In-Seok;Seol, Dong-Won;Cho, Sung-Hwoan;Song, Young-Chae;Choi, Hee-Jung;Noh, Choong-Hwan;Myoung, Jung-Goo;Kim, Jong-Man
    • Ocean and Polar Research
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    • 제28권3호
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    • pp.287-290
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    • 2006
  • Eye growth and lens diameter of brown croaker Miichthys miiuy were positively allometric between hatching and 180 days post-hatch (d.p.h.). Eye growth in relation to head length and head height was nearly isometric. Eyes were formed completely at 14 d.p.h. At this age, the eye has a crystalline lens, an optic nerve fiber layer, a ganglion cell layer, an inner plexiform layer, an inner nuclear layer, an outer plexiform layer, an outer nuclear layer, an outer limiting membrane, and a pigment epithelium. The essential demands that must be met by the retina in this species pertain to light sensitivity and spatial resolution.

Effect of Processing Method on Change of Water Soluble Dietary Fiber of Fagopyrum tataricum

  • Kim, Dong-Eun;Lee, Beom-Goo;Park, Cheol-Ho;Kang, Wie-Soo
    • Agricultural and Biosystems Engineering
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    • 제6권2호
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    • pp.70-76
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    • 2005
  • Seed, stem and sprout of F. tataricum were separately milled using the ultra fine mill under the same condition to investigate the effect of roasting or extruding on the particle size, microstructure and water solubility of dietary fiber. The mean particle size of MR (roasting) is increased in stem and sprout, and that of ME (extruding) is increased in seed, compared to that of control. The microscopic views of seed show that control has the spherical shape but ME the larger and irregular shape, and those of stem and sprout show that control has the needle like shape but ME more rounded shape. Water solubility index of ME is much higher than that of control or MR in seed, stem and sprout. It shows that seed, stem and sprout are damaged more in extruding than in roasting, and the starch and cell wall structure must be destroyed to change the water insoluble dietary fiber into the water soluble dietary fiber.

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The effect of Nafion$^{(R)}$ ionomer content/distribution and relative humidities on PEMFC performances of MEAs prepared by a CCM spraying method

  • 김근호;전유택
    • 한국신재생에너지학회:학술대회논문집
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    • 한국신재생에너지학회 2011년도 추계학술대회 초록집
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    • pp.87.1-87.1
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    • 2011
  • For commercial applications, MEA development must be optimized in order to achieve high performance and low cost. There are many factors that affect the performance of MEA. Especially, the optimization of the method for preparing catalyst layer has great effect on the performance of MEA. Various methods have been used to prepare the catalyst layer of MEA. Among them, spraying method has a merit in that catalysis lay can be prepared with very flexible changes in catalyst layer as well as in the solvent composition of catalyst ink. In addition, in order to reduce the time required for manufacturing catalyst layer, an effort has been made to change the nozzle size and injection pressure of spray system. Further, the operation condition of spray system was changed in various ways in an effort to prepare optimum catalyst layer of MEA. Having optimized the operation condition of spraying system, comprehensive and diverse experiments were carried out concerning various factors that affect the performance of MEA. The present research report describes the results of more sub-categorized and more detailed experiments about the important factors (Nafion$^{(R)}$ ionomer, Relative humidity) which have been shown in previous experiments to exert greater effect on the performance of MEA.

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전기자동차 충전구 위치에 따른 전자파 방사특성에 관한 연구 (A Study on Electromagnetic Interference of Electric Vehicles with Variations of Charging Device Inlet Location)

  • 권순민;우현구
    • 한국자동차공학회논문집
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    • 제24권6호
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    • pp.694-701
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    • 2016
  • According to revolutionary developments in automobile technologies, eco-friendly advanced vehicles (hybrid vehicle, hydrogen fuel-cell vehicle, electric vehicle, etc.) are rapidly increasing. The electromagnetic compatibility is getting more important for development of a vehicle because those advanced vehicles are driven by electric energy and equipped with more electric systems. In general, electromagnetic compatibility tests consist of an electromagnetic interference(EMI) test and an electromagnetic susceptibility(EMS) test. EMI test of the electric vehicles are needed not only in driving mode but also in charging mode because they must be recharged by much electric energy for driving. Depending on vehicle manufacturers, the charging device type and the location of charging device inlet in electric vehicles are various. In this paper, in order to investigate EMI of electric vehicles in charging mode in consideration of the direction of measuring antenna and the location of charging device inlet, a series of electromagnetic emission tests are conducted using three electric vehicles (neighborhood electric vehicle, electric vehicle and electric vehicle-bus). The test results show that electromagnetic emission measurements in charging mode are dependent on the direction of measuring antenna and the location of charging device inlet.