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Foeniculum vulgare essential oil nanoemulsion inhibits Fusarium oxysporum causing Panax notoginseng root-rot disease

  • Hongyan Nie;Hongxin Liao;Jinrui Wen;Cuiqiong Ling;Liyan Zhang;Furong Xu;Xian Dong
    • Journal of Ginseng Research
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    • v.48 no.2
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    • pp.236-244
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    • 2024
  • Background: Fusarium oxysporum (F. oxysporum) is the primary pathogenic fungus that causes Panax notoginseng (P. notoginseng) root rot disease. To control the disease, safe and efficient antifungal pesticides must currently be developed. Methods: In this study, we prepared and characterized a nanoemulsion of Foeniculum vulgare essential oil (Ne-FvEO) using ultrasonic technology and evaluated its stability. Traditional Foeniculum vulgare essential oil (T-FvEO) was prepared simultaneously with 1/1000 Tween-80 and 20/1000 dimethyl sulfoxide (DMSO). The effects and inhibitory mechanism of Ne-FvEO and T-FvEO in F. oxysporum were investigated through combined transcriptome and metabolome analyses. Results: Results showed that the minimum inhibitory concentration (MIC) of Ne-FvEO decreased from 3.65 mg/mL to 0.35 mg/mL, and its bioavailability increased by 10-fold. The results of gas chromatography/mass spectrometry (GC/MS) showed that T-FvEO did not contain a high content of estragole compared to Foeniculum vulgare essential oil (FvEO) and Ne-FvEO. Combined metabolome and transcriptome analysis showed that both emulsions inhibited the growth and development of F. oxysporum through the synthesis of the cell wall and cell membrane, energy metabolism, and genetic information of F. oxysporum mycelium. Ne-FvEO also inhibited the expression of 2-oxoglutarate dehydrogenase and isocitrate dehydrogenase and reduced the content of 2-oxoglutarate, which inhibited the germination of spores. Conclusion: Our findings suggest that Ne-FvEO effectively inhibited the growth of F. oxysporum in P. notoginseng in vivo. The findings contribute to our comprehension of the antifungal mechanism of essential oils (EOs) and lay the groundwork for the creation of plant-derived antifungal medicines.

Bell's palsy after concomitant chemoradiotherapy: a case report and literature review

  • Sul Gi Choi;Ji Seok Oh;Hoon Myoung;Mi Hyun Seo
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.24 no.2
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    • pp.129-135
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    • 2024
  • Concomitant chemoradiotherapy (CCRT) treated patients experience various complications. We present a rare case of post-CCRT Bell's palsy and describe its various possible causes, so as to increase awareness among clinicians about Bell's palsy being a CCRT-associated adverse effect. The patient was a 48-year-old man diagnosed with squamous cell carcinoma who presented with post-CCRT Bell's palsy. After radiotherapy for 6 weeks (overall 67.5 Gy) and four rounds of cisplatin chemotherapy, he complained of paralysis of the entire left face. A test was performed 33 days after the last CCRT session to differentiate Bell's palsy from other causative factors. Based on magnetic resonance imaging findings, facial nerve invasion due to tumor size increase was determined to not cause Bell's palsy. Inflammation of the left Eustachian tube was observed. Hence, steroids and famciclovir were administered, which markedly improved the facial paralysis symptoms within 56 days after facial paralysis development. In conclusion, patients can develop Bell's palsy owing to complex effects of various CCRT mechanisms. Although the exact cause of Bell's palsy has not been identified and the effectiveness of drug treatment was questionable in this case, unlikely causative factors should be excluded through various tests and appropriate and timely measures must be adopted.

Analysis of Hybrid Additive Cellular Automata (하이브리드 가산 셀룰라 오토마타의 분석)

  • Cho, Sung-Jin;Choi, Un-Sook;Kim, Han-Doo;Hwang, Yoon-Hee;Kim, Jin-Gyoung;Kim, Bong-Soo
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2008.05a
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    • pp.221-224
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    • 2008
  • Anghelescu et al. proposed a block cryptosystem based on 8-cell hybrid additive cellular automata with cycle length 8 using state transition rules 51, 60 (or 102). All states must divided into the same cycles in the diagram of the cellular automata. But there exist cellular automata which don't satisfy this condition in Anghelescu et al.'s cryptosystem. In this paper we analyze hybrid additive cellular automata and propose an improved method.

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Differentiating Plasma Regions Through the non-Linear Relationship between the Band-gap and the Deposition-rate of a-Si Thin Films (a-Si 막의 Band-gap과 Deposition-rate간의 비선형 거동을 통한 플라즈마 영역의 경계 규명)

  • Park, Sung-Yul L.;Kim, Hee Won;Kim, Sang Duk;Kim, Jong Hwan;Kim, Bum Sung;Lee, Don Hee
    • 한국신재생에너지학회:학술대회논문집
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    • 2010.06a
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    • pp.72.1-72.1
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    • 2010
  • Thin film a-Si solar cells deposited by PECVD have many advantages compared to the traditional crystalline Si solar cells. They do not require expensive Si wafer, the process temperature is relatively low, possibility of scaling up for mass production, etc. In order to produce thin film solar cells, understanding the relationship between the material characteristics and deposition conditions is important. It has been reported by many groups that the band gap of the a-Si material and the deposition rate has an linear relationship, when RF power is used to control both. However, when the process pressure is changed in order to control the deposition rate and the band gap, a diversion from the well known linear relationship occurs. Here, we explain this diversion by the deposition condition crossing different plasma regions in the Paschen curve with a simple model. This model will become a guide to which condition a-Si thin films must be fabricated in order to get a high quality film.

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Pore-filling membrane with ionic liquids immobilized by cross-linking for high temperature PEFCs (고온 PEFC용 수소이온 전도 향상을 위한 가교된 이온성 액체를 갖는 세공충진막)

  • Baek, Ji-Suk;Choi, Young-Woo;Lee, Mi-Soon;Yang, Tae-Hyun;Kim, Chang-Soo
    • 한국신재생에너지학회:학술대회논문집
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    • 2010.11a
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    • pp.80.2-80.2
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    • 2010
  • The development of high temperature-proton exchange fuel cell (HT-PEFC) is a key in solving the problem of carbon monoxide poisoning of the platinum at anode as well as water management in PEFCs operated below $90^{\circ}C$. In order to overcome these main issues, PEFCs must be operated at high temperature above $120^{\circ}C$. Ionic liquids are available for HT-PEFC due to exhibiting non-volatility and thermal stability. Ionic liquids are however leached out from polymeric matrix resulting in the increase of gas permeability. In this study, we have prepared and characterized the composite membranes with the ionic liquids consisting of 1-(4-vinylbenzyl)-3-butyl imidazolium chloride immobilized by the cross-linkers in pore-filling membrane to prevent to be leached out from the membrane. We confirmed that cross-linked ionic liquids were not leached out from the composite membranes through the various characteristic analyses. It was also verified that the prepared membranes are thermally stable from the result of TG analysis. The pore-filling membranes with the immobilized ionic liquids have a high proton conductivity over $10^{-2}$ S/cm at high temperature (> $120^{\circ}C$).

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The Characteristic of L-shape and Triangular Slot Antenna

  • Narkcharoen, K.;Charkrit, P.;Anantrasirichai, N.;Wakabayashi, T.
    • 제어로봇시스템학회:학술대회논문집
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    • 2003.10a
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    • pp.1680-1683
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    • 2003
  • To describe the performance of an antenna, some parameters are necessary. Some of the parameters are interrelate and not all of them must be specified for complete description of antenna performance. The parameters in characteristics of printed antenna for this analysis are radiation pattern, input impedance, VSWR, S parameter and electromagnetic field. In this paper we will consider two shaped of slot antennas one is triangular slot antenna and other is L - shape slot antenna for compare the radiation pattern, return loss, and VSWR. Two slot antennas are designed to have a resonant frequency at 10 GHz. The microstrip line is designed to be 50 ohms in order to match the measurement system, it has the substrate of the thickness = 1.52 mm and dielectric constant (${\varepsilon}_r$) 2.17. The problem space in the FDTD analysis are $60{\times}123{\times}100$ cells for L-shape slot antenna and $50{\times}171{\times}120$ cells for triangular slot antenna with the cell dimensions ${\Delta}x=0.152\;mm.$, ${\Delta}y={\Delta}z=0.15\;mm.$

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Fabrication of Carbon Microcapsules Containing Silicon Nanoparticles-Carbon Nanotubes Nanocomposite for Anode in Lithium Ion Battery

  • Bae, Joon-Won;Park, Jong-Nam
    • Bulletin of the Korean Chemical Society
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    • v.33 no.9
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    • pp.3025-3032
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    • 2012
  • Carbon microcapsules containing silicon nanoparticles (Si NPs)-carbon nanotubes (CNTs) nanocomposite (Si-CNT@C) have been fabricated by a two step polymerization method. Silicon nanoparticles-carbon nanotubes (Si-CNT) nanohybrids were prepared with a wet-type beadsmill method. A polymer, which is easily removable by a thermal treatment (intermediate polymer) was polymerized on the outer surfaces of Si-CNT nanocomposites. Subsequently, another polymer, which can be carbonized by thermal heating (carbon precursor polymer) was incorporated onto the surfaces of pre-existing polymer layer. In this way, polymer precursor spheres containing Si-CNT nanohybrids were produced using a two step polymerization. The intermediate polymer must disappear during carbonization resulting in the formation of an internal free space. The carbon precursor polymer should transform to carbon shell to encapsulate remaining Si-CNT nanocomposites. Therefore, hollow carbon microcapsules containing Si-CNT nanocomposites could be obtained (Si-CNT@C). The successful fabrication was confirmed by scanning electron microscopy (SEM) and X-ray diffraction (XRD). These final materials were employed for anode performance improvement in lithium ion battery. The cyclic performances of these Si-CNT@C microcapsules were measured with a lithium battery half cell tests.

Fertility preservation for patients with hematologic malignancies: The Korean Society for Fertility Preservation clinical guidelines

  • Lee, Dong-Yun;Kim, Seul Ki;Kim, Miran;Hwang, Kyung Joo;Kim, Seok Hyun
    • Clinical and Experimental Reproductive Medicine
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    • v.44 no.4
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    • pp.187-192
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    • 2017
  • Although the survival rate of hematologic malignancies in young patients is very high, cytotoxic therapies such as chemotherapy and total body irradiation therapy can significantly reduce a patient's reproductive capacity and cause irreversible infertility. Early ovarian failure also commonly occurs following additional cancer treatment, bone marrow transplantation, or autologous transplantation. Because the risk of early ovarian failure depends on the patient's circumstances, patients with a hematologic malignancy must consult health professionals regarding fertility preservation before undergoing treatments that can potentially damage their ovaries. While it is widely known that early menopause commonly occurs following breast cancer treatment, there is a lack of reliable study results regarding fertility preservation during hematologic malignancy treatment. Therefore, an in-depth discussion between patients and health professionals about the pros and cons of the various options for fertility preservation is necessary. In this study, we review germ cell toxicity, which occurs during the treatment of hematologic malignancies, and propose guidelines for fertility preservation in younger patients with hematologic malignancies.

Factors Influencing Psychosocial Well-Being in Family Caregivers of People with Amyotrophic Lateral Sclerosis (근위축성측삭경화증 가족 돌봄제공자의 심리사회적 안녕감에 영향을 미치는 요인)

  • Chu, Hyeon Sik;Tak, Young Ran;Kim, Seung Hyun
    • Journal of Korean Academy of Nursing
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    • v.48 no.4
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    • pp.454-464
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    • 2018
  • Purpose: The purpose of this study was to identify factors influencing psychosocial well-being in family caregivers of patients with amyotrophic lateral sclerosis (ALS). Methods: A descriptive correlational design was used. The transactional model of stress and coping was used to investigate the psychosocial well-being of 137 family caregivers of patients with ALS. Data were collected through self-reported questionnaires from January to November 2016. Data were analyzed using an independent t-test, one-way ANOVA, Pearson's correlation, and hierarchical multiple regression analysis with the SPSS WIN 21.0 program. Results: The regression model had an adjusted $R^2$ of .49, which indicated that meaning-focused coping, social support, ALS patient-family caregiver relationship (especially a spousal relationship), and tracheostomy were significant predictors of caregivers' psychosocial well-being. Conclusion: Meaning-focused coping and social support significantly influenced caregivers' psychosocial well-being. Therefore, interventions to improve caregivers' psychosocial well-being must focus on increasing meaning-focused coping and social support resources.

Reliability Verification of Battery Disconnecting Unit (BDU 신뢰성 검증)

  • Yoon, Hye-Lim;Ryu, Haeng-Soo;Ji-Hong;Hong-Tae, Park
    • Proceedings of the KIEE Conference
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    • 2011.07a
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    • pp.866-867
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    • 2011
  • As part of the green growth, The Green Car has attracted wide attention. Types of the Green Car are Electric Vehicle, Plug-in Hybrid Electric Vehicle, Hybrid Electric Vehicle, Fuel Cell Vehicle and Clean Diesel Vehicle. Of these, The electric vehicle is equipped with the BDU(Battery Disconnecting Unit). BDU is supplying stable battery power and blocking it to protect electrical system of the electric vehicle. The BDU consists of electric components such as current sensor, fuse and pre-charge resistor. These must pass Voltage withstand test, Salt mist test, Thermal shock test, Vibration test and Short-circuit test commonly to verify reliability of the electric components. In addition, The current sensor should be verified whether normal operation. The breaking capacity of fuse should be verified. The durability of pre-charge resistor should be verified by supplying battery power and blocking it repeatedly. The reliability of BDU as well as the electric vehicle is secured by verifying the reliability of electric components. In addition, It will contribute to the acceleration and promotion of Green Car Technology.

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