• Biomolecules & Therapeutics
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• v.18 no.4
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• pp.363-374
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• 2010

Growing evidence suggests a prominent role for leptin in human cancer progression. The intricate pattern of leptin cross-talk with other associated signaling pathways is a critical area of research that will ultimately contribute to comprehending the role of leptin in cancer progression. This review summarizes a portion of the current understanding of leptin signaling, with a critical focus on its contribution to tumor cell invasion and metastasis. Five topics are addressed in this review: (1) Leptin receptor, (2) Leptin signaling, (3) Leptin and cancer, and (4) Leptin and tumor invasion. Due to the complex cellular effects of leptin, a more precise understanding of leptin signaling pathways must still be elucidated. Leptin is clearly a major factor for stimulating tumor progression through a complex spectrum of interplay and cross-talk among various signaling molecules. An understanding of the role of leptin in invasion and metastasis will provide valuable information for establishing strategies to modulate leptin signaling, which should be a high priority for the development of anti-cancer therapeutics.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2008.04a
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• pp.49-50
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• 2008

OCB mode has advantages such as fast response time and wide viewing angle. But it has inevitable shortcoming which initial splay state must be changed to bend state. To overcoming this problem, OCB cell filled LC with RM monomer was cured by UV when voltage applied. Through previously mentioned methods, even if electric field is none, bend state was made by stabilized LC director. In this paper, we investigated the electric characteristics of polymer stabilized OCB mode.

• Journal of Applied Biological Chemistry
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• v.58 no.2
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• pp.113-116
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• 2015

Silver materials may be toxic in humans because they can enter the body and accumulate, typically in the lungs. We hypothesized that the cytotoxicity of naive silver materials is affected by their size and shape. Our in vitro assays revealed that the overall toxicity was in the following order: submicro-particles>wires>micro-particles. These results contrast with previous studies, which showed that silver wires are the most toxic among the three tested materials, possibly due to differences in cell lines. Evaluations of in vivo pulmonary toxicity revealed eryptosis in the cavity lining of the lung sections. The observed eryptosis was consistent with the in vitro results. Our results indicate that silver materialinduced cytotoxicity must be measured and compared using various methods.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2004.02a
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• pp.42-50
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• 2004

The pool $(3m{\times}6m{\times}10m{\times}$ in Irradiated Materials Examination Facility is generally used to transport irradiated materials between a moving cask and hot-cell. During the operation in the pool such as loading/unloading the cask, holding specimen and bucket elevation, water maybe contaminated by radioactive or contaminated impurities from irradiated materials. Then, it must be purified and filtered continuously to keep lower radioactivity than that of regulation prescribed by RCA Korea Activity in a part of radioactive contamination control. This paper described radioactive contamination distribution of water as transported materials, which is related to effective operation of purification and filtration system.

• Bulletin of the Korean Mathematical Society
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• v.43 no.3
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• pp.657-669
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• 2006

In this paper, we analyze a leaky bucket (LB) scheme with queue length dependent arrival rates. In other words, if the queue length exceeds an appropriate threshold value on buffer, the arrivals need to be controlled. In ATM networks, if the congestion occurs, the input traffics must be controlled (reduced) for congestion resolution. By the bursty and correlated properties of traffics, the arrivals are assumed to follow a Markov-modulated Poisson process (MMPP). We derive the loss probability and the waiting time distribution for arbitrary cell. The analysis is done by using the embedded Markov chain and supplementary variable method. We also present some numerical examples to show the effects of our proposed LB scheme.

• Journal of the Korea Society of Computer and Information
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• v.21 no.10
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• pp.1-10
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• 2016

In this paper, we propose an approach to generate machine readable context annotations for SPARQL Results. According to W3C Recommendations, the retrieved data from RDF or OWL data sources are represented in tabular form, in which each cell's data is described by only type and value. The simple query result form is generally useful, but it is not sufficient to explain the semantics of the data in query results. To explain the meaning of the data, appropriate annotations must be added to the query results. In this paper, we generate the annotations from the basic graph patterns in user's queries. We could also manipulate the original queries to complete the annotations. The generated annotations are represented using the RDFa syntax in our study. The RDFa expressions in HTML are machine-understandable. We believe that our work will improve the trustworthiness of query results and contribute to distribute the data to meet the vision of the Semantic Web.

• Smart Structures and Systems
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• v.17 no.5
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• pp.743-751
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• 2016

An ongoing research project is devoted to the design and implementation of a satellite based asset tracking for supporting emergency management in crisis operations. Due to the emergency environment, one has to rely on a low power consumption wireless communication. Therefore, the communication hardware and software must be designed to match requirements, which can only be foreseen at the level of more or less likely scenarios. The latter aspect suggests a deep use of a simulator (instead of a real network of sensors) to cover extreme situations. The former power consumption remark suggests the use of a minimal computer (Raspberry Pi) as data collector.

• Transactions of the Korean hydrogen and new energy society
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• v.20 no.5
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• pp.439-446
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• 2009

This paper investigates the dehydration and RDF (Refuse Derived Fuel) production of organic wastes, livestock manure and sewerage sludge with pressurized hydrothermal treatment process. The renewable technology for the organic wastes must involve short treatment time required, reusable energy source, anti-odor and viruses, low cost for the treatment, and well-fertilization. The pressurized hydrothermal treatment process promotes to evaporate moisture in the waste after being shortly treated in a reactor, which uses steam and heat supplied by an external boiler. By the pressurized steam, the cell walls of the waste break and effectively release the internal moisture. Then, the dried waste can be mixed with waste vinyls to produce RDF with a higher heating value as high as 6,700 kcal/kg.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2004.11a
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• pp.53-56
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• 2004

This paper presents the improved burn-in method for the reliability of SRAM in MCP Semiconductor reliability is commonly improved through the burn-in process. Reliability problem is more significant in the Multi Chip Package, because of including over two devices in a package. In the SRAM-based Multi Chip Package, the failure of SRAM has a large effect on the yield and quality of the other chips - Flash Memory, DRAM, etc. So, the quality of SRAM must be guaranteed. To improve the quality of SRAM, we applied the improved wafer level burn-in process using multi cell selection method in addition to the current used methods. That method is effective in detecting special failure. Finally, with the composition of some kinds of methods, we could achieve the high qualify of SRAM in Multi Chip Package.

• Asian-Australasian Journal of Animal Sciences
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• v.13 no.2
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• pp.258-264
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• 2000

Production systems for cloned pigs are very important not only for an increase in production of superior animals but also for the production of knockout animals with organs that do not contain antigens for xenotransplantation or to analyze functions of isolated human genes. At present, however, effective systems have not been developed. We have tried to produce cloned pigs by transfering cultured cells into enucleated oocytes and obtained some cloned embryos. To develop a production system for cloned pigs, the basic technologies needed to support such an effort must be improved.