• Journal of the Korean Society of Physical Medicine
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• v.5 no.4
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• pp.569-576
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• 2010

Purpose : This study was aimed at determining the effects of community-based exercise program to improve leg muscle strength and balance for elderly women. Methods : This study was nonequivalent control group pre-post test design. Subjects were assigned to two different groups(exercise group=11, control group=7). Exercise group performed community-based exercise program for 8 weeks. Outcome measures included leg muscle strength, balance, walking velocity, activities of daily living(ADL), exercise self-efficacy and health-related quality of life(QoL). The collected data analyzed by independent t-test and paired t-test. Results : Leg muscle strength, walking velocity and mental component summary(QoL) were significantly improved in the exercise group. But balance and exercise self-efficacy were significantly worsened in the control group. There were no significant difference between groups after 8 weeks of community-based exercise. Conclusion : These results suggested that the community-based exercise program is effective for elderly women in improving leg muscle strength, walking velocity and mental component summary(QoL).

• Korean Journal of Exercise Nutrition
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• v.23 no.2
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• pp.1-6
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• 2019

[Purpose] Strenuous exercise often induces skeletal muscle damage, which results in impaired performance. Sphingolipid metabolism contributes to various cellular processes, including apoptosis, stress response, and inflammation. However, the relationship between exercise-induced muscle damage and ceramide (a key component of sphingolipid metabolism), is rarely studied. The present study aimed to explore the regulatory role of sphingolipid metabolism in exercise-induced muscle damage. [Methods] Mice were subjected to strenuous exercise by treadmill running with gradual increase in intensity. The blood and gastrocnemius muscles (white and red portion) were collected immediately after and 24 h post exercise. For 3 days, imipramine was intraperitoneally injected 1 h prior to treadmill running. [Results] Interleukin 6 (IL-6) and serum creatine kinase (CK) levels were enhanced immediately after and 24 h post exercise (relative to those of resting), respectively. Acidic sphingomyelinase (A-SMase) protein expression in gastrocnemius muscles was significantly augmented by exercise, unlike, serine palmitoyltransferase-1 (SPT-1) and neutral sphingomyelinase (N-SMase) expressions. Furthermore, imipramine (a selective A-SMase inhibitor) treatment reduced the exercise-induced CK and IL-6 elevations, along with a decrease in cleaved caspase-3 (Cas-3) of gastrocnemius muscles. [Conclusion] We found the crucial role of A-SMase in exercise-induced muscle damage.

• The Korean Journal of Physiology and Pharmacology
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• v.25 no.6
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• pp.585-592
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• 2021

Cisplatin has been reported to cause side effects such as muscle wasting in humans and rodents. The physiological mechanisms involved in preventing muscle wasting, such as the regulation of AKT, PGC1-α, and autophagy-related factor FOXO3a by MuRF 1 and Atrogin-1, remain unclear following different types of exercise and in various skeletal muscle types. Eight-week-old male Wistar rats (n = 34) were assigned to one of four groups: control (CON, n = 6), cisplatin injection (1 mg/kg) without exercise (CC, n = 8), cisplatin (1 mg/kg) + resistance exercise (CRE, n = 9) group, and cisplatin (1 mg/kg) + aerobic exercise (CAE, n = 11). The CRE group performed progressive ladder exercise (starting with 10% of body weight on a 1-m ladder with 2-cm-interval grids, at 85°) for 8 weeks. The CAE group exercised by treadmill running (20 m/min for 60 min daily, 4 times/week) for 8 weeks. Compared with the CC group, the levels of the autophagy-related factors BNIP3, Beclin 1, LC3-II/I ratio, p62, and FOXO3a in the gastrocnemius and soleus muscles were significantly decreased in the CRE and CAE groups. The CRE and CAE groups further showed significantly decreased MuRF 1 and Atrogin-1 levels and increased phosphorylation of AKT, FOXO3a, and PGC1-α. These results suggest that both ladder and aerobic exercise directly affected muscle wasting by modulating the AKT/PGC1-α/FOXO3a signaling pathways regardless of the skeletal muscle type.

• The Journal of Korean Physical Therapy
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• v.22 no.4
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• pp.49-55
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• 2010

Purpose: The purpose of this study was to investigate the effects of isokinetic exercise on muscular performance and thickness of the quadriceps muscle. Methods: Twenty one healthy male students participated in this study. Participants were divided into 2 groups: $60^{\circ}/sec$ of isokinetic exercise (n=7), $180^{\circ}/sec$ (n=7) and $300^{\circ}/sec$ (n=7). Each group did isokinetic exercises 3 times a week for 6 weeks. Each group was measured for peak torque per body weight, average power and total work using a Biodex System 4. Rectus femoris, vastus laterails and vastus medialis were measured for muscle thickness using a SONOACE 6000C. Data were analyzed by repeated measures ANOVA using SPSS 12.0. Results: There was a significant time-related effect in peak torque per body weight, average power and total work. There was a significant time-related effect in the vastus medialis and rectus femoris muscle thickness. However, there was a significant group by time interaction for vastus laterlis muscle thickness. Conclusion: Isokinetic exercise may be an effective method for improving quadriceps muscle performance regardless of angular velocity. However, the thickness of the rectus femoris and vastus medialis muscle may be increased regardless of the angular velocity of the quadriceps muscle the vastus lateralis muscle may only be remarkably improved when doing exercise with low angular velocity.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.3
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• pp.1212-1219
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• 2012

This study was to investigate the balancing and clinical abilities trunk muscle stabilization exercise and trunk muscle resistive exercise of stroke patients having surface changes in balance of body. The subjects of this study were 30 stroke patients(15 males and 15 females) that three times a week for 12 weeks at the same time point and with the same amount of exercise. They were separated into two groups and did reinforcing exercise on trunk muscle stabilization exercise and trunk muscle resistive exercise for three times a week for twelve weeks. It were measured balancing ability, they performed functional standing balance test, functional forward arm stretching test. performance-oriented mobility assessment, berg balance scale. The balancing exercises were modified from preceding studies and consisted of 6 difference exercises. The functional standing test with open and close eyes and performance-oriented mobility assessment, the trunk muscle stabilization exercise group and the trunk muscle resistive exercise group improved significantly. The forward arm stretching was test the trunk muscle stabilization exercise group more improved. This study found that the balancing exercise on trunk muscle stabilization exercise was more effective than trunk muscle resistive exercise for stroke patients. Thus, trunk muscle stabilization exercise has more positive effects on the improvement of balancing abilities of stroke patients.

• Journal of Society of Preventive Korean Medicine
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• v.12 no.3
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• pp.115-128
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• 2008

Purpose : This study was performed to distinguish the muscle activation of vastus medialis and biceps femoris through open and closed kinetic chain exercise. Methods : 31 healthy male and female students in Daegu Health College were participated in this study. All subjects were conducted three types open and closed kinetic chain exercises to examine muscle activity during the last four seconds using the sEMG system. Collected EMG data were normalized using the maximal voluntary isometric contraction(MVIC). Results : MVIC of each muscle was showed significantly increased(p<0.5). In the case of open chain exercise, the type 3 exercise most increased than type 2 and 3 exercise in vastus medialis than biceps femoris muscle. The closed chain exercise presented type 6 exercise most increased than type 4 and 5 exercise in biceps femoris than vastus medialis. Conclusion : This study finally proved that muscle activity which maintains stability of knee differ from depending on the types of exercises. Therefore, the combination of the two chain exercises is believed to greatly contribute to increments in muscle activity.

• The Journal of Korean Physical Therapy
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• v.31 no.4
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• pp.193-198
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• 2019

Purpose: This study examined the effects of plank exercise combined with breathing and arm exercises on the external oblique, internal oblique, and transverse abdominal muscle thickness. Methods: Thirty healthy adults consisting of 12 males and 18 females from K area were divided into a plank exercise combined with breathing and arm exercises group (n = 15) and a plank exercise only group (n=15). The changes in muscle thickness before the exercise and four and eight weeks after the exercise were analyzed using a two-way repeated analysis of variance (ANOVA). The significance level was set to ${\alpha}=0.05$. Post-hoc t-tests were conducted to detect the interactions between the time and groups, and the significance level was set to ${\alpha}=0.01$. Results: According to the experimental results, the external oblique abdominal muscle showed significant differences over time (p<0.05). The internal oblique abdominal muscle also showed significant differences over time and in the interactions between the time and groups (p<0.05). The transverse abdominal muscle showed significant differences over time, in the interactions between time and groups, and in the changes between the groups (p<0.05). Conclusion: The results indicated that plank exercise combined with breathing and arm movement exercises led to increases in the abdominal muscle thickness. These types of exercises may be useful in lumbar stabilization rehabilitation treatment.

• Journal of the Korean Society of Physical Medicine
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• v.10 no.4
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• pp.9-14
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• 2015

PURPOSE: Low-intensity exercise with restriction of blood flow has been proposed as an alternative exercise to secure the disadvantage of a high-intensity resistance exercise. However, studies of how affects the muscle using functional exercise are lacking. Thus, the purpose of this study was to investigate knee extensor muscle strength during stair exercise of functional exercise with leg blood flow restriction. METHODS: Twenty two healthy young adults with no history of musculoskeletal or neurogical disorder were participated in this study. participant were randomized into either non-restriction group(11 subject) or restriction group (11 subject). The restriction blood cuff attached to the proximal end of the leg. Measurement of knee extensor strength was used by cybex dynamometer. Data analyzed in independent t-test and paired t-test. RESULTS: Knee extensor muscle strength was significantly different between groups. Also, there were significant differences in the strength of knee extensor within the group. CONCLUSION: This study found that stair exercise with restriction of blood flow did influence to knee extensor muscle strength. These results will also be able to promote the effect of increasing the muscle power applied to functional exercise. Henceforth, studies will be made in the intervention method that can be applied to health vulnerable person.

• Journal of International Academy of Physical Therapy Research
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• v.2 no.2
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• pp.274-280
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• 2011

This study was designed to analyze repetitive dorsiflexion and plantarflexion exercises in ankles have effects on the muscle tones of triceps, vastus medialis and gastrocnemius. 25 healthy woman volunteers(ankle dorsiflexion exercise group: 13, ankle plantarflexion exercise group: 12) participated in the two ankle exercise models, which have performed 3 times a week for 3 weeks. Myotonometer was used to measure the muscle tones of the triceps, vastus medialis, gastrocnemius muscles, and measurements were performed before and after the application of the each exercise model. Repeated measured paired t-test and independent t-test was used to determine a statistical significance. The group of repetitive dorsiflexion exercise of the ankle have effects on the muscle tones of triceps, vastus medialis and gastrocnemius (p>.05). The group of repetitive plantarflexion exercise of the ankle have effects on the muscle tones of triceps, vastus medialis and gastrocnemius(p>.05). The groups of repetitive dorsiflexion and plantarflexion exercise of the ankle have effects on the muscle tones of triceps, vastus medialis and gastrocnemius(p>.05).

• Journal of International Academy of Physical Therapy Research
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• v.11 no.4
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• pp.2212-2220
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• 2020

Background: Repetitive damage to the ankle joint causes chronic ankle instability, and studies comparing the effects of exercise in open and closed chains as a treatment method are very rare. Objectives: To investigate the effects of open and closed kinetic exercises on muscle activity and dynamic balance of ankle joint in adults with chronic ankle instability. Design: Single-blind randomized controlled trial. Methods: The selected 30 subjects are randomly divided into open kinetic chain exercise experimental group (EGI, n=10), closed kinetic chain exercise experimental group (EGII, n=10), and stretching control group (CG, n=10). Open and closed kinetic exercises lasted 30 minutes three times a week for six weeks and stretching exercises performed four actions for 20 seconds and five sets. The measurement tools using surface electromyography to measure muscle activity in the ankle joint. The dynamic balance of the ankle was evaluated using the Y-Balance test. Results: Following the intervention, closed and open kinetic chain exercise group showed significant difference in tibialis anterior and gastrocnemius muscle activity and dynamic balance (P<.05). However, no significant difference in tibialis anterior and gastrocnemius muscle activity and dynamic balance between closed and open kinetic chain exercise group (P<.05). Conclusion: This study provides evidence that closed and open kinetic chain exercise can be presented as an effective exercise for the muscle activity of ankle muscle and dynamic balance of the subject with chronic ankle instability.