• Genomics & Informatics
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• v.14 no.4
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• pp.187-195
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• 2016

In genetic association studies with high-dimensional genomic data, multiple group testing procedures are often required in order to identify disease/trait-related genes or genetic regions, where multiple genetic sites or variants are located within the same gene or genetic region. However, statistical testing procedures based on an individual test suffer from multiple testing issues such as the control of family-wise error rate and dependent tests. Moreover, detecting only a few of genes associated with a phenotype outcome among tens of thousands of genes is of main interest in genetic association studies. In this reason regularization procedures, where a phenotype outcome regresses on all genomic markers and then regression coefficients are estimated based on a penalized likelihood, have been considered as a good alternative approach to analysis of high-dimensional genomic data. But, selection performance of regularization procedures has been rarely compared with that of statistical group testing procedures. In this article, we performed extensive simulation studies where commonly used group testing procedures such as principal component analysis, Hotelling's $T^2$ test, and permutation test are compared with group lasso (least absolute selection and shrinkage operator) in terms of true positive selection. Also, we applied all methods considered in simulation studies to identify genes associated with ovarian cancer from over 20,000 genetic sites generated from Illumina Infinium HumanMethylation27K Beadchip. We found a big discrepancy of selected genes between multiple group testing procedures and group lasso.

• Knowledge Management Research
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• v.20 no.2
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• pp.1-24
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• 2019

This tutorial introduces procedures and methods for performing structural equation modeling using R. To do this, we present advanced analysis methods based on structural equation model such as mediation effect analysis, moderation effect analysis, moderated mediation effect analysis, and multiple-group analysis with R program code using R lavaan package that supports structural equation modeling. R is flexible and scalable, unlike traditional commercial statistical packages. Therefore, new analytical techniques are likely to be implemented ahead of any other statistical package. From this point of view, R will be a very appropriate choice for applying new analytical techniques or advanced techniques that researchers need. Considering that various studies in the social sciences are applying structural equations modeling techniques and increasing interest in open source R, this tutorial is expected to be useful for researchers who are looking for alternatives to existing commercial statistical packages.

• Korean Journal of Human Ecology
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• v.20 no.6
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• pp.1135-1151
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• 2011

This study examined green consumption behavior according to the lifestyles of college students. The data were collected from 314 college students in Yeungnam region by a self-administered questionnaire. Frequencies, Cronbach's alpha, factor analysis, cluster analysis, chi-square tests, one-way analysis of variance, Duncan's multiple range tests, Pearson's correlation analysis, and multiple regression analyses were conducted by SPSS Windows V.18.0. According to the result of factor analysis, lifestyles were categorized into six factors: thrift-saving type, enthusiastic activity type, brand ostentation type, freedom-seeking type, material oriented type, and practice-seeking type. Cluster analysis showed respondents belonged to one of four groups: thrift practice group, indifference group, freedom-seeking group, and material ostentation group. The levels of green purchase behavior, green usage behavior and green disposal behavior of the respondents was not high. The thrift practice group showed higher levels of green purchase behavior, green usage behavior, and green disposal behavior. Finally, according to multiple regression analyses, environmental consciousness, knowledge about green consumption, lifestyle groups were the significant factors affecting green consumption behaviors. These results imply that green consumption education for college students should be activated to induce green life.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.11 no.4
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• pp.1889-1910
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• 2017

This paper investigates a protocol so-called Adaptive Harvest Then Transmit (AHTT) for wireless powered communication networks (WPCNs) in multiple-input single-output (MISO) downlink systems, which assists in transmitting signals from a multi-antenna transmitter to a single-antenna receiver. Particularly, the power constrained relay is supplied with power by utilizing radio frequency (RF) signals from the source. In order to take advantage of multiple antennas, two different linear processing schemes, including Maximum Ratio Combining (MRC) and Selection Combination (SC) are studied. The system outage capacity and ergodic capacity are evaluated for performance analysis. Furthermore, the optimal power allocation is also considered. Our numerical and simulation results prove that the implementation of multiple antennas helps boost the energy harvesting capability. Therefore, this paper puts forward a new way to the energy efficiency (EE) enhancement, which contributes to better system performance.

• Journal of the korean academy of Pediatric Dentistry
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• v.25 no.4
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• pp.691-703
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• 1998

Saliva is obviously potential medium to protect the dental caries by not only physical clearing effect, but aggregating action of protein with bacteria. Nevertheless, we still do not understand how the dental caries occur and what brings the individual difference in caries prevalence. In the regards of dental caries prevalence, we hypothesized that the composition of salivary protein might be different from caries susceptible group to caries resistant group. The purposes of this experiment were focused on the molecular analysis of salivary proteins from the subjects who were involved in multiple caries. Electrophoretic analysis was done on the whole saliva collected from the children with and without multiple caries. We found 86.2% of subjects with multiple caries has approximately 120 KDa protein band while 30.4% in the healthy subjects. And the concentration of the total protein on the subjects with multiple caries is significantly higher than that of the healthy group. However, it turned out that the difference of the salivary composition does not affect the bacterial adhesion to hydroxyapatite bead. With regards of enzymes in saliva, the activity of ${\alpha}-amylase$ and lactate dehydrogenase does not have any significant difference between both groups. However, the concentrations of $Na^+\;and\;Cl^-$ in saliva from multiple caries group is higher than that of the control group. Taken all together, it may be concluded that 120 KDa protein in saliva may be associated with the process of dental caries, also the high concentration of protein and $Na^+,\;Cl^-$ in saliva may be linked to dental caries development as a cofactors.

• The korean journal of orthodontics
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• v.23 no.3 s.42
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• pp.341-358
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• 1993

This study was investigated to evaluate the morphologic characteristics of deepbite tendency as multiple factors. The subjects consisted of 60 control subjects(male 25, female 35) and 137 deephite patients(68 male, 69 female). The deepbite group was composed of 4 subgroups(Class I 44, Class II div. 1 40, Class II div. 2 13, Class III 40). The mean age was 21.57 year for the control group 21 year for deepbite group lateral cephalograph in centric occlusion were taken, traced, and digitized for each subject. The statistically computerized analysis was carried out with SAS program. The results were as follows ; 1. In deepbite group, saddle angle is lesser than that of normal group. 2. The vertical dysplasia is prominent on anterior lower face and is closely related with mandibular form and inclination. 3. Without consideration of sagittal relationship, the dental factors such as curve of Spee, interincisal angle, U1 to upper lip length were prominent in the deepbite group. 4. Although there were individual variances in the perioral soft tissue profile, the lip presented more protruded pattern. 5. There was no significant difference in hyoid bone position and inclination between normal and deepbite group. 6. The multivariate discriminant analysis between normal and Class I deepbite group showed that curve of Spee, AB-MP angle, interincisal angle, articular agnle were critical in the determination of deepbite as multiple factors.

• Journal of the Korean Society of Clothing and Textiles
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• v.22 no.6
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• pp.781-792
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• 1998

The purpose of this study was to investigate the factors related to the propensity for symbolic consumption and the effects of materialism, reference group, and social stratification on the symbolic consumption in clothing. Data were administered to 957 adolescence in middle, high school, and college student living in Seoul, Chonju, Sunchon, Yousu, and Kwangyang from May to June 1997. For analysis of the data, frequencies, percentage, means, standard deviation, factor analysis, 1-test, one-way anomia, duncan's multiple range test, and multiple regression analysis were employed. The results of this study can be summarized asfollows. 1) Symbolic consumption, materialism, and reference group were found to have the significant differences according to social stratification groups by objectivemethod. The higher social stratification is, the higher symbolic consumption, materialism, and reference group were. 2) symbolic consumption were proven to have the significant differences according to materiaiism and reference group. The higher materialism and the influence of referencegroup indicated, the higher symbolic consumption. 3)according to the results of the regression analysis examining the relative influences of variables affecting symbolic consumption in clothing, the relative importance of the variables are in order of : the influences of the reference group, materialism, social stratification, status inconsistency type (occupation-income), and their explanatory power totalled 40.0%.

• Archives of Pharmacal Research
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• v.11 no.1
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• pp.45-51
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• 1988

The feature of resolution enhancement by derivative operation is linked to one of the multivariate analysis, which is multiple linear regression with two options, all possible and stepwise regression. Examined samples were synthetic mixtures of 5 vitamins, thiamine mononitrate, riboflavin phosphate, nicotinamide, pyridoxine hydrochloride and ascorbic acid. All components in mixture were quantified with reasonably good accuracy and precision. Whole data processing procedure was accomplished on-line by the development of three computer programs written in APPLESOFT BASIC language.

• Korean Journal of Child Studies
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• v.26 no.5
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• pp.217-232
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• 2005

This study examined the effects of an art program based on multiple intelligence theory on children's creativity and spatial ability. The art education program focused on three processes : perception, production and reflection. Subjects were 68 five-year-old children. The experimental design was 'The Untreated Control Group Design with Pretest & Posttest'. ANCOV was employed for statistical analysis. Results were that the children in the experimental group scored significantly higher on creativity and spatial ability than the children in the control group. Results imply that an art education program based on multiple intelligence theory can be an effective teaching model for improving children's creativity and spatial ability.

• Journal of the Korean Society of Clothing and Textiles
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• v.24 no.4
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• pp.487-497
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• 2000

The purpose of this study was performed 1) to study the differences in advertisement expression and brand preference according to the lifestyle groups of high school girl students(Sports Uninterest Group, Friend Preference/Fashion Uninterest Group, Sports Preference/Horne Oriented Group. fashion Interest Group, and Confidence Group) and 2) to investigate the effects on the brand preference of adolescents of lifestyle, brand and advertisement image and advertisement expression forms. The subjects selected for the final analysis were high school girl students living in Pusan, Seoul and Taejeon, Korea. The statistics used for data analysis were factor analysis, one-way ANOVA, Duncan's multiple range test, stepwise multiple regression, frequency distribution and percentage by the SPSS program. The results of this study were as follows: 1. The preferences of advertising expression forms were significantly different among lifestyle groups: the Friend Preference/Fashion Uninterest Group preferred to sex appealing advertising expression form less than other groups. 2. The brand preferences were significantly different among lifestyle groups: the Confidence Group preferred brand less than other groups in general. 3. The brand preferences were affected by life style, brand and advertising image and preferences of advertising expression forms. And brand image influenced most significantly on the brand preferences.