• 한국항공우주학회지
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• 제34권5호
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• pp.93-100
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• 2006

본 논문에서는 레이더와 원격측정시스템으로부터 수신되는 다중센서자료를 모사하는 시뮬레이터 설계와 이들 자료를 융합하기 위한 알고리듬 개발에 대하여 소개한다. 설계된 데이터 시뮬레이터는 실제 센서 시스템으로부터 얻게 되는 시간의 비동기, 통신지연, 다중 갱신주기들을 갖는 모의센서 자료를 생성하며 실제적인 센서 모델을 이용하여 측정 잡음을 생성한다. 융합알고리듬은 센서 바이어스 상태를 고려한 PVA모델을 기초로 21차 분산형 칼만 필터로 설계되었고, 센서의 이상이나 정상적이 아닌 측정치를 검출하기 위한 로직도 포함되었다. 설계된 알고리듬을 시뮬레이터에서 생성한 모의 자료 및 실제 자료를 적용하여 검증하였다.

• International Journal of Fuzzy Logic and Intelligent Systems
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• 제9권3호
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• pp.166-171
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• 2009

In recent years, video detection systems have been implemented in various infrastructures such as airport, public transportation, power generation system, water dam and so on. Recognizing moving objects in video sequence is an important problem in computer vision, with applications in several fields, such as video surveillance and target tracking. Segmentation and tracking of multiple vehicles in crowded situations is made difficult by inter-object occlusion. In the system described in this paper, the mean shift algorithm is firstly used to filter and segment a color vehicle image in order to get candidate regions. These candidate regions are then analyzed and classified in order to decide whether a candidate region contains a license plate or not. And then some characters in the license plate is recognized by using the fuzzy ARTMAP neural network, which is a relatively new architecture of the neural network family and has the capability to learn incrementally unlike the conventional BP network. We finally design a license plate recognition system using the mean shift algorithm and fuzzy ARTMAP neural network and show its performance via some computer simulations.

• Macromolecular Research
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• 제17권3호
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• pp.192-196
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• 2009

Recently, the multi-screening of target materials has been made possible by the development of the surface plasmon resonance (SPR) imaging method. To adapt this method to biochemical analysis, the multi-patterning technology of protein microarrays is required. Among the different methods of fabricating protein microarrays, the microfluidic platform was selected due to its various advantages over other techniques. Microfluidic devices were designed and fabricated with polydimethylsiloxane (PDMS) by the replica molding method. These devices were designed to operate using only capillary force, without the need for additional flow control equipment. With these devices, multiple protein-patterned sensor surfaces were made, to support the two-dimensional detection of various protein-protein interactions with SPR. The fabrication technique of protein microarrays can be applied not only to SPR imaging, but also to other biochemical analyses.

• Mass Spectrometry Letters
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• 제12권2호
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• pp.31-40
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• 2021

Probable human carcinogenic compounds nitrosamines, have been detected as by-product impurities in sartan pharmaceuticals in recent years which has drawn worries for medication safety. To provide a sensitive and effective method for the quality control of sartan pharmaceuticals, this study established a feasible gas chromatography-tandem mass spectrometry (GC-MS/MS) method for simultaneous determination of 13 nitrosamines. The target analytes were separated on a DB-WAX Ultra Inert column (30 m × 0.25 mm; i.d., 0.25 ㎛) and were then subjected to electron impact ionization in multiple reaction monitoring mode. The established method was validated and further employed to analyze authentic samples. Limits of detection (LODs) and limits of quantification (LOQs) of the 13 nitrosamines were 15-250 ng/g and 50-250 ng/g, respectively, which also exhibited intra-day and inter-day accuracies of 91.4-104.8%, thereby satisfying validation criteria. Five nitrosamines, viz., N-nitrosodiethylamine, N-nitrosodimethylamine, N-nitrosodiphenylamine, N-nitrosomorpholine, and N-nitrosopiperidine were detected at concentrations above their LODs in 68 positive samples out of 594 authentic samples from seven sartans.

• 시스템엔지니어링학술지
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• 제16권2호
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• pp.131-140
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• 2020

The characteristics of ballistic missiles are changing rapidly but studies have mostly focused on fragmentary flight trajectory analysis estimating the changing characteristics of some types, while there is a lack of research on comprehensive and efficient ballistic search, detection and prediction for missiles including the new types that have been gaining attention lately. This paper analyzes the flight trajectory characteristics of ballistic missiles at various ranges considering flight path angle adjustment, specific impulse and drag force with altitude based on the optimized equations of motion reflecting the parameters of North Korea's general and new types of ballistic missiles. The flight trajectory characteristics of representative ranges for each ballistic missile were analyzed by adjusting the flight path angle in the minimum energy method, lofted method, and depressed method. In addition, High value target can attacked by ballistic missiles considering flight path angle adjustment at various points. It's expected to be used to Threat Evaluation and Weapon Allocation, and deployment of defense systems by interpreting the analysis of the latest Iskander-class ballistic missiles and the new multiple rocket launcher.

• 한국항행학회논문지
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• 제27권5호
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• pp.574-579
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• 2023

레이다 비행시험은 다양한 조건의 표적, 클러터, 재밍을 모의하는데 많은 제약 사항이 있다. 따라서, 본 연구에서는 운용 시나리오에 따라 운용 모의 기능을 수행하는 레이다 비행 모의 장치를 개발하였다. 개발된 레이다 비행모의 장치는 레이다 빔 운용 모의, 레이다 동작 제어, 모의 신호 발생, 비행자세모의를 통해 레이다의 다양한 임무 환경을 모의한다. 레이다 비행모의 장치는 레이다 임무 환경(클러터, 재밍 등)이 포함된 모의 표적(단일, 다중) 신호를 생성하고 변조하여 RF를 통해 레이다로 송신한다. 개발된 레이다 비행모의장치와 AESA 레이다를 연동하여, 다양한 비행 시나리오를 기반으로 하여 모의 표적을 탐지하고 탐지 결과 확인을 통해 레이다 성능을 검증하였다.

• 로봇학회논문지
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• 제18권4호
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• pp.463-471
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• 2023

This paper proposes a method to estimate the level of interest shown by visitors towards a specific target, a guide robot, in spaces where a large number of visitors, such as exhibition halls and museums, can show interest in a specific subject. To accomplish this, we apply deep learning-based behavior recognition and object tracking techniques for multiple visitors, and based on this, we derive the behavior analysis and interest level of visitors. To implement this research, a personalized dataset tailored to the characteristics of exhibition hall and museum environments was created, and a deep learning model was constructed based on this. Four scenarios that visitors can exhibit were classified, and through this, prediction and experimental values were obtained, thus completing the validation for the interest estimation method proposed in this paper.

• Korean Journal of Radiology
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• 제23권6호
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• pp.598-614
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• 2022

While ultrasound (US) is considered an important tool for hepatocellular carcinoma (HCC) surveillance, it has limited sensitivity for detecting early-stage HCC. Abbreviated MRI (AMRI) has recently gained popularity owing to better sensitivity in its detection of early-stage HCC than US, while also minimizing the time and cost in comparison to complete contrast-enhanced MRI, as AMRI includes only a few essential sequences tailored for detecting HCC. Currently, three AMRI protocols exist, namely gadoxetic acid-enhanced hepatobiliary-phase AMRI, dynamic contrast-enhanced AMRI, and non-enhanced AMRI. In this study, we discussed the rationale and technical details of AMRI techniques for achieving optimal surveillance performance. The strengths, weaknesses, and current issues of each AMRI protocol were also elucidated. Moreover, we scrutinized previously performed AMRI studies regarding clinical and technical factors. Reporting and recall strategies were discussed while considering the differences in AMRI protocols. A risk-stratified approach for the target population should be taken to maximize the benefits of AMRI and the cost-effectiveness should be considered. In the era of multiple HCC surveillance tools, patients need to be fully informed about their choices for better adherence to a surveillance program.

• 미생물학회지
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• 제43권2호
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• pp.91-99
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• 2007

인간면역결핍바이러스(Human immunodeficiency virus; HIV) 진단을 위한 다중, 초고속실시간 PCR법을 개발하였다. 검출대상의 DNA 염기서열은 env 유전자를 기반으로 설계되었으며, 각기 HIV-1 특이 495염기(gi_1184090) 및 HIV-2 특이 294염기(gi_1332355)의 DNA를 안정상의 이유로 PCR을 이용한 유전자합성법으로 제작하여 사용하였다. 초고속 실시간 PCR은, PCR의 회전 중 각 단계별 설정시간을 극단적으로 축소하여, $1\;{\mu}l$의 PCR 용액용 microchip을 탑재할 수 있는 $Genspector^{TM}$을 사용하여 수행하였다. DNA 증폭과 융점분석을 포함한 총 PCR 검색 시간은 HIV_1 및 HIV-2 모두에서 15분 이내로 완료되었으며, 각기 최소 2.3개의 합성 env 유전자로부터도 HIV-1 특이 117염기와 HIV-2 특이 119염기의 PCR산물을 성공적으로 증폭시킬 수 있는 민감성을 보여주었다. 이런 형식의 실시간 PCR법을 본 연구에서 초고속실시간 PCR (Ultra-rapid real-time PCR)이라 명명하였다. 이는 본 연구의 대상인 HIV에 대한 보조적 진단방법일 뿐 아니라 PCR 검색법이 사용되고 있는 다른 병원체에 대하여도 적용될 수 있을 것이나, 우선 HIV 임상시료에 대한 본 검색법의 효용성 실험 등 추가 연구가 필요할 것으로 사료된다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권9호
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• pp.4321-4326
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• 2012

The current study aimed at exploring the knowledge and beliefs of men aged forty years and over towards prostate cancer screening and early detection in three Arab countries. The field work was conducted in three countries; Saudi Arabia, Egypt and Jordan, during the period February through December 2011. Our target population were men aged 40 years and over. It was a population-based cross sectional study comprising 400 subjects at each site. In addition to socio-demographic data, history of the present and past medical illness, practice history of prostatic cancer examination, family history of cancer prostate; participants were inquired about their knowledge and attitude towards prostate cancer and screening behavior using two different likert scales. The percentage of participants who practiced regular prostate check up ranged from 8-30%. They had poor knowledge and fair attitude towards prostate cancer screening behavior, where the mean total knowledge score was $10.25{\pm}2.5$, $10.76{\pm}3.39$ and $11.24{\pm}3.39$ whereas the mean total attitude score was $18.3{\pm}4.08$, $20.68{\pm}6.4$ and $17.96{\pm}5.3$ for Saudi Arabia, Egypt and Jordan respectively. The respondents identified the physicians as the main sources of this information (62.4%), though they were not the main motives for regular checkup. Knowledge was the only significant predictor for participants' attitude in the multiple regression models. Participants' attitudes depends mainly on level of knowledge and quantity of information provided to the patients and their families. Such attitudes should rely on a solid background of proper information and motivation from physicians to enhance and empower behaviors towards prostate cancer screening practices.