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Stereotactic Radiosurgery for Recurrent Glioblastoma Multiforme using Yeungnam Localization Device - Technical note and Clinical trial - (뇌정위적 방사선 절제술에 필요한 위치선정용기구 제작과 치험 2예)

  • Shin, Sei-One;Kim, Sung-Kyu;Kim, Myung-Se;Kim, Oh-Lyong;Cho, Soo-Ho
    • Radiation Oncology Journal
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    • v.10 no.1
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    • pp.101-105
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    • 1992
  • Authors performed a stereotactic radiosurgery with multiple noncoplanar convergent photon beams of linear accelerator (NELAC-1018 18 MeV, NEC) using a specially designed Yeungnam localization device for two patients with recurrent glioblastoma multiforme. One patient had 2 cm sized and the other 4 cm sized mass on the CT images. After single session of treatment with 15 and 20 Gy, headache was improved in a few days after radiosurgery with no remarkable untoward reactions. Our experience with these two patients were encouraging and we found that our localization device, which is easily adjustable and inexpensive, could be a valuable tool for stereotactic radiosurgery particularly in the treatment of recurrent brain tumor.

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The Effect of Health Education on the Performance of Health Promoting Behavior in College Students (건강교육이 대학생의 건강증진 행위에 미치는 영향)

  • 박정숙;박청자;권영숙
    • Journal of Korean Academy of Nursing
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    • v.26 no.2
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    • pp.359-371
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    • 1996
  • This study has been done for the purpose of testing the effect of health education on the performance of health promoting behavior in college students, and identifying the factors affecting health promoting behaviors. A Nonequivalent control group posttest research design was used. Two hundred thirty college students at K College in T city were studied. Of them, 114 who attended a systematic health education session for three hours a week during one semester were the experimental group. And 116 college students who were chosen of matched sampling of grade, class and sex were the control group. This study was conducted from March 1 to July 2, 1995. The instruments used for this study included a survey of general characteristics, perceived health status, self-esteem, health promoting behavior and health locus of control. Analysis of data was done by use of mean, 1-test, Pearson correlation coefficient and multiple regression. The results of this study are summarized as follows : 1) The average item score for the health promoting behavior was low at 2.52. In the sub-categories, the highest degree of performance was ‘harmonious relationships’, following ‘sanitary life’, ‘self-esteem’, ‘rest and sleep’, and ‘emotional support’ and the lowest degree was ‘professional health management’. 2) Hypothesis 1 that the college students who get health education will have a higher degree of health promoting behavior than the college students who do not get health education was accepted. There was a statistically significant difference between the average of the experimentalgroup, 2.60, and the average of the control group, 2.45.(t=11.30, p=0.0009). 3) Hypothesis 2 that the college students who get health education will have a higher score of perceived health status than college students who do not get the health education was rejected. (t=1.13, p=0.289) 4) Performance of health promoting behavior was positively correlated with self-esteem and grade and negatively correlated with perceived health status. 5) The most important factor affecting performance of health promoting behavior was self-esteem. The following suggestions are made based on the above results : 1) Replication of the research is needed to confirm effects of health education. 2) More effective health education programs need to be developed through by modification of teaching methods and content analysis of health education. 3) Other factors affecting health promoting behavior should be identified. 4) Nursing colleges or departments of nursing should make an effort to develop and carry out various health education programs for the health promotion of all college students.

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Factors to Predict Successful Harvest during Autologous Peripheral Hematopoietic Stem Cell Collection

  • Kim, Mun-Ja;Jin, Soo-He;Lee, Duk-Hee;Park, Dae-Weon;Koh, Sung-Ae;Lee, Kyung-Hee;Hyun, Myung-Soo;Kim, Min-Kyoung
    • Biomedical Science Letters
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    • v.18 no.2
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    • pp.131-138
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    • 2012
  • Autologous peripheral blood stem cell transplantation (PBSCT) has been used as a major treatment strategy for hematological malignancies. The number of CD34 positive cells in the harvested product is a very important factor for achieving successful transplantation. We studied the factors that can predict the number of CD34 positive cells in the harvested product of acute myelocytic leukemia (AML), multiple myeloma (MM) and Non-Hodgkin's lymphoma (NHL) patients after mobilizing them with chemotherapy plus G-CSF. A total of 73 patients (AML 19 patients, MM 28 patients, NHL 26 patients) with hematological malignancies had been mobilized with chemotherapy and granulocyte colony-stimulating growth factor from April, 2000 to February, 2012. Group's characteristics, checkup opinion of pre-peripheral blood on the day of harvest & outcome of PBSC were analyzed and evaluated using SPSS statistics program after grouping patients as below; group 1: CD34 cell counts < $2{\times}10^6/kg$ (n=16); group 2: $2{\times}10^6/kg{\leq}CD34$ cell counts < $6{\times}10^6/kg$ (n=32); group 3: CD34 cell counts ${\geq}6{\times}10^6/kg$ (n=25). We analyzed the clinical characteristics, the peripheral blood (PB) parameters and the number of CD34 positive cells in the PB and their correlation with the yield of CD34 positive cells collected from the mobilized patients. The total number of leukapheresis sessions was 263 (mean: 3.55 session per patient), and the mean number of harvested CD34 positive cells per patient was $7.37{\times}10^6/kg$. The number of CD34 positive cells in product was significantly correlated with the number of platelet and CD34 positive cells in peripheral blood (P<0.05). The number of PB CD34 positive cells was the best significant factor for the quantity of harvested CD34 positive cells on the linear regression analysis (P<0.05). Many factors could influence the mobilization of peripheral blood stem cells. Platelet count and PB CD34 positive cells count were the two variables which remained to be significant in multivariate analysis. Therefore, the number of platelet and CD34 positive cells in peripheral blood on the day of harvest can be used as an accurate predictor for successful peripheral blood stem cell collection.

The Effects of Laughing Programs on Elementary Students Anxiety and Self-esteem (웃음프로그램이 초등학생의 불안과 자아존중감에 미치는 효과)

  • Jang, Hyun Sun;Jeong, Sohee
    • The Journal of Korean Society for School & Community Health Education
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    • v.16 no.2
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    • pp.101-114
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    • 2015
  • Objectives: Find out how it affects anxiety situations and self-esteem targeting the critical period of development of self-esteem in the lower grades in elementary school based on laughter therapy in having a positive influence on physical health promotion and positive emotional cultivation. And to verify the effects of laughter activity was to provide preliminary data on mental health education and guidance of school life. Methods: By targeting Ulsan Y elementary school, second grade 7 class, 191 students conducted test self-esteem and anxiety. Homogeneous group of experimental and control groups were selected in each one class. Classified as experimental group carried out laughter activity programs and control group did not carried out. Also the separation of the application program before and after, then it were performed preliminary-post-further as same checklist. Program coverage period is 12 weeks and 30 minutes per session was conducted twice a week. Differences between the experimental group and the comparison group has conducted the independent samples t-test, and if the difference between the experimental group and the comparison group were verified by performing a variance analysis(Oneway ANOVA) and post multiple comparisons. Results: Analysis of the experimental group decreased anxiety in the post-test than the pre-test as a whole, in particular, sub-areas of concern, shame and shyness was shown to be effective, and decision of the difficulty was not significant by insignificant reduction. In addition, self-esteem was increased in overall score. The score of collective self-esteem and School life self-esteem were more increased, and domestic self-esteem was not significant by slight increases. In contrast, the comparison group showed no significant difference in all areas of anxiety and self-esteem of pre-test and post-test. Conclusions: In experiments on self-esteem and anxiety of lower grade in elementary school through laughter activity program, comparison group it did not show an effect by accident, and experimental group showed meaningful effects that self-esteem was increased and anxiety was reduced. Thus, laughter activity can be seen that improving self-esteem, anxiety reduction and etc, is very beneficial to mental health.

Design of Secure Scheme based on Bio-information Optimized for Car-sharing Cloud (카 쉐어링 클라우드 환경에서 최적화된 바이오 정보 기반 보안 기법 설계)

  • Lee, Kwang-Hyoung;Park, Sang-Hyeon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.11
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    • pp.469-478
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    • 2019
  • Car-sharing services have been settled on as a new type of public transportation owing to their enhanced convenience, expanded awareness of practical consumption patterns, the inspiration for environmental conscientiousness, and the diffusion of smart phones following the economic crisis. With development of the market, many people have started using such services. However, security is still an issue. Damage is expected since IDs and passwords are required for log-in when renting and controlling the vehicles. The protocol suggested in this study uses bio-information, providing an optimized service, and convenient (but strong) authentication with various service-provider clouds registering car big data about users through brokers. If using the techniques suggested here, it is feasible to reduce the exposure of the bio-information, and to receive service from multiple service-provider clouds through one particular broker. In addition, the proposed protocol reduces public key operations and session key storage by 20% on mobile devices, compared to existing car-sharing platforms, and because it provides convenient, but strong, authentication (and therefore constitutes a secure channel), it is possible to proceed with secure communications. It is anticipated that the techniques suggested in this study will enhance secure communications and user convenience in the future car-sharing-service cloud environment.

The Effectiveness of Explicit Form-Focused Instruction in Teaching the Schwa /ə/ (영어 약모음 /ə/ 교수에 있어서 명시적 Form-Focused Instruction의 효과 연구)

  • Lee, Yunhyun
    • The Journal of the Korea Contents Association
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    • v.20 no.8
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    • pp.101-113
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    • 2020
  • This study aimed to explore how effective explicit form-focused instruction (FFI) is in teaching the schwa vowel /ə/ to EFL students in a classroom setting. The participants were 25 female high school students, who were divided into the experimental group (n=13) and the control group (n=12). One female American also participated in the study for a speech sample as a reference. The treatment, which involves shadowing model pronunciation by the researcher and a free text-to-speech software and the researcher's feedback in a private session, was given to the control group over a month and a half. The speech samples, for which the participants read the 14 polysyllabic stimulus words followed by the sentences containing the words, were collected before and after the treatment. The paired-samples t test and non-parametric Wilcoxon signed-rank test were used for analysis. The results showed that the participants of the experimental group in the post-test reduced the duration of the schwa by around 40 percent compared to the pre-test. However, little effect was found in approximating the participants' distribution patterns of /ə/ measured by the F1/F2 formant frequencies to the reference point, which was 539 Hz (F1) by 1797 Hz (F2). The findings of this study suggest that explicit FFI with multiple repetitions and corrective feedback is partly effective in teaching pronunciation.

The Effects of Changes In Body Composition Through High Intensity Circuit Training On Spine Curvature And Low Back Pain Among Middle-Aged Men With Abdominal Obesity (고강도서키트트레이닝에 의한 신체조성의 변화가 복부비만 중년남성의 척추만곡도와 요부통증에 미치는 영향)

  • Kim, Chae-Won;Kim, Jung-Hoon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.5
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    • pp.346-356
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    • 2018
  • Overweight and abdominal obesity caused by sedentary lifestyle may induce deconditioned and atrophied extensor musculature of the lumbar spine and be a potential risk factor for low back pain (LBP). Therefore, this study was conducted to evaluate the validity of high intensity circuit training (HICT) on weight loss and subsequent alleviation of spine curvature (SC) and visual analog scale (VAS) among middle aged men with abdominal obesity. The training program (1 exercise session for 30 minutes, three times a week for 12 weeks) consisted of 12 different functional exercises based on core strengthening multiple joint circuit training. Portions of the obesity index related to body composition were positively changed, which improved the angles of thoracic kyposis and lumbar lordosis, which appeared to effectively reduce lower back pain. Taken together, HICT specifically designed for LBP effectively decreased obesity related body composition and was superior to other treatments for decreasing aggravation of the spine curvature and LBP caused by abdominal obesity; however, weight loss should be the primary treatment target for LBP patients.

A Multicast Delivery Technique for VCR-like Interactions in Collaborative P2P Environment (협력 P2P 환경에서 VCR 기능을 위한 멀티캐스트 전송 기법)

  • Kim Jong-Gyung;Kim Jin-Hyuk;Park Seung-Kyu
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.31 no.7B
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    • pp.679-689
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    • 2006
  • Delivering multicast stream is one of the cost-saving approach in the large scale VOD environment. Because implementing VCR-like interactions for user's convenience in the multicast streaming system involves complex problems, we need the proper solutions for them. In this paper, we propose a hybrid scheme which uses the general P2P and the patching scheme with the Collaborative Interaction Streaming Scheme(CISS). CISS provides jumping functionability to the appropriate multicast session after VCR-like interaction in the environment in which multiple peers transmit VCR-like interaction streams to the VCR-like functionability request node to reduce the loads generated by frequent join or departure of peers at the multicast tree during providing VCR-like functionability. Therefore, with the proposed scheme we can distribute network traffic and reduce control overhead and latency. And to evaluate the performance of proposed scheme we compare it in the aspect of the performance of streaming delivery topology, control overhead and streaming quality with P2Cast[10] and DSL[11]. The simulation result shows that proposed P2Patching reduces about 30% of process overhead and enhances about $25{\sim}30%$ of streaming quality compared with DSL.

Effect of Flipped Learning Education in Physical Examination and Practicum (플립러닝을 활용한 건강사정 및 실습 교육 효과)

  • Cho, Mi-Kyoung;Kim, Mi Young
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.12
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    • pp.81-90
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    • 2016
  • The objective of this study was to investigate the effect of an education method applying the flipped learning technique for college students. Both self-directed learning readiness and educational performance before and after applying the flipped learning were examined. After applying the flipped learning technique, teacher-student interaction, learning satisfaction, and learning motivation were identified. The correlation of each variable was examined after applying the flipped learning technique to investigate its influence on learning motivation. A total of 68 second-year nursing students enrolled in E University were analyzed. A difference between before and after applying the flipped learning was analyzed by the paired t-test; a correlation between the variables was analyzed via Pearson's correlation coefficient; and an influence on the dependent variable learning motivation was analyzed using the stepwise multiple regression analysis. The results showed that self-directed learning readiness increased before and after applying the flipped learning technique with statistical significance, and the difference of educational performance was not significant. After an education session applying the flipped learning technique, a learning motivation demonstrated a significantly positive correlation with self-directed learning readiness (r=0.33, p=.006), college student educational performance (r=0.51, p<.001), teacher-student interaction (r=0.72, p<.001), and learning satisfaction (r=0.79, p<.001). A significantly positive correlation was also observed between the other variables. Factors influencing learning motivation were learning satisfaction and teacher-student interaction. The explanatory power for learning motivation in the regression model considering these two variables was 71.3% (F=80.66, p<.001). Therefore, to enhance learning motivation in applying the flipped learning technique, it is necessary to increase learning satisfaction and to establish a strategy that further vitalizes the teacher-student interaction.

The Effects of Acupuncture on the Electroencephalogram of Patients with Stroke (자침이 중풍환자의 뇌파 변화에 미치는 영향)

  • Yoon, Ga-Young;Park, Ji-Min;Kim, Dong-Hyuk;Seon, Jong-In;Kang, Jung-Won;Nam, Dong-Woo;Lee, Seung-Deok;Choi, Do-Young;Lee, Jae-Dong
    • Journal of Acupuncture Research
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    • v.29 no.5
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    • pp.1-16
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    • 2012
  • Objectives : The purpose of this study was to examine the effects of manual acupuncture at the $LI_4$, $ST_{36}$ and $LR_3$ on Electroencephalogram(EEG) of patients with stroke. Methods : 32 channel EEG measurement was carried out in 35 Stroke patients(23 males and 12 females). EEG was measured for 21 minutes(made up of 7 sessions, 1 session means 3 minutes time interval) including 15 minutes(5 sessions) of acupuncture time. Power spectrum analysis was used as a measure of complexity. Statistical analysis was performed using Linear mixed model and DUNNETT's multiple comparison. Results : The results were as follows; 1. EEG amplitude was reduced during acupuncture except electrodes PG1 and PG2. 2. There was a notable change during 6~9 minutes after needling in ${\delta}{\cdot}{\beta}{\cdot}{\gamma}$ wave, and during 6~9 minutes after needling in ${\Theta}{\cdot}{\alpha}$ wave. Overall, during 6~9 minutes after needling. 3. TP8 is a common significant electrode among five wave forms. Conclusions : These results suggest that TP8 could be typical electrodes and change of EEG compared to baseline happens most often during 6~9 minutes after manipulated acupuncture at the $LI_4$, $ST_{36}$ and $LR_3$ of patients with stroke.