• 대한한의학회지
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• 제25권2호
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• pp.77-86
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• 2004

Objectives: To study the features of appetite and dining habit according to Sasang constitution. The results of this study will be helpful to diagnose a Sasang constitution. Methods: There were 588 patients (248 men, 340 women) who answered questionnaire and were diagnosed by the Sasang Constitution Specialist at the Constitutional Clinic of Dongguk Bundang Oriental Hospital. Using the responses to the questionnaire and several statistical techniques such as homogeneity test and multiple comparison, we tried to find the characteristics of each constitution depending on its dining behavior. Results & Conclusions: As a result of the analysis of the questionnaire, Taeumin and Soyangin have a heavy appetite (p<0.01), but the appetite of Soyangin and Soeumin tends to be irregular (p<0.01). Especially, the appetite of Soeumin tends to change according to his feelings (p<0.0I). Taeumin and Soyangin eat more and faster in comparison with Soeumin (p<0.01).

• Communications for Statistical Applications and Methods
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• 제30권3호
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• pp.331-341
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• 2023

Handling missing values in data analysis is essential in constructing a good prediction model. The easiest way to handle missing values is to use complete case data, but this can lead to information loss within the data and invalid conclusions in data analysis. Imputation is a technique that replaces missing data with alternative values obtained from information in a dataset. Conventional imputation methods include K-nearest-neighbor imputation and multiple imputations. Recent methods include missForest, missRanger, and mixgb ,all which use machine learning algorithms. This paper compares the imputation techniques for datasets with mixed datatypes in various situations, such as data size, missing ratios, and missing mechanisms. To evaluate the performance of each method in mixed datasets, we propose a new imputation performance measure (IPM) that is a unified measurement applicable to numerical and categorical variables. We believe this metric can help find the best imputation method. Finally, we summarize the comparison results with imputation performances and computational times.

• Asian Pacific Journal of Cancer Prevention
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• 제14권6호
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• pp.3663-3667
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• 2013

Background: Multiple myeloma is a malignant silent incurable plasma cell disorder. The present study aimed to assessed the activation of the oxidative stress pathway in afected patients Materials and Methods: Advanced oxidation protein products (AOPPs), malondialdehyde (MDA), adenosine deaminase (ADA), total antioxidant capacity (TAC) levels, glutathione, ascorbic acid (vitamin C), ${\alpha}$-tocopherol (vitamin E) in addition to related enzymes glutathione peroxidase (GSH-Px), glutathione reductase (GSH-R) and superoxide dismutase (SOD) were analyzed in sixty patients with multiple myeloma before and after one month treatment with induction therapy. Results: The results of the study showed a significant elevation in AOPPs, MDA, ADA levels in patients with multiple myeloma before and after treatment in comparison to healthy control samples In contrast TAC glutathione, vitamin C and E, and the antioxidant enzymes levels were decreased significantly. On comparing samples of MM patients after treatment, there was significant increase of TAC glutathione, vitamin C and E, and the antioxidant enzymes in parallel with decreasing AOPPs, MDA and ADA levels in comparison with samples of patients before treatment. Conclusions: The results indicate oxidative stress and DNA damage activity increase in MM and are alleviated in response to therapy.

• Journal of Mechanical Science and Technology
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• 제16권6호
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• pp.819-828
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• 2002

An analytical method is presented for evaluation of the steady state periodic behavior of nonlinear systems. This method is based on the substructure synthesis formulation and a MS (multiple scales) procedure, which is applied to the analysis of nonlinear responses. The proposed procedure reduces the size of large degrees-of-freedom problem in solving nonlinear equations. Feasibility and advantages of the proposed method are illustrated with the nonlinear rotating machine system as an example of large mechanical structure systems. In addition, its efficiency for nonlinear response prediction will be shown by comparison of other conventional methods.

• Nuclear Engineering and Technology
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• 제51권2호
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• pp.579-587
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• 2019

This paper provides further validation of the burst pressure estimation equations for multiple axial surface cracked steam generator tubes, recently proposed by the authors based on analytical local collapse load approach against systematic FE damage analysis results of Alloy 690 tubes with twin axial surface cracks. Wide ranges of the relative crack depth and multiple crack configurations are considered. Comparison shows good agreements, giving sufficient confidence of the proposed equations.

• 대한의용생체공학회:의공학회지
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• 제29권4호
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• pp.329-336
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• 2008

Recently, causality analysis of source time series extracted from EEG or MEG signals is becoming of great importance in human brain mapping studies and noninvasive diagnosis of various brain diseases. Two approaches have been widely used for the analyses: one is independent component analysis (ICA), and the other is multiple signal classification (MUSIC). To the best of our knowledge, however, any comparison studies to reveal the difference of the two approaches have not been reported. In the present study, we compared the performance of the two different techniques, ICA and MUSIC, especially focusing on how accurately they can estimate and separate various brain electrical signals such as linear, nonlinear, and chaotic signals without a priori knowledge. Results of the realistic simulation studies, adopting directed transfer function (DTF) and Granger causality (GC) as measures of the accurate extraction of source time series, demonstrated that the MUSIC-based approach is more reliable than the ICA-based approach.

• 전자공학회논문지B
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• 제32B권10호
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• pp.1286-1293
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• 1995

Modified equivalent lumped element model for square spiral inductors have been derived. This model shows more accurate analysis performance than conventional models, and gives reliable design parameters. And this model is made through comparison among distributed multiple coupled line, numerical analysis and experimental data.

• Biomolecules & Therapeutics
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• 제30권1호
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• pp.98-116
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• 2022

The small GTPase RhoA has been studied extensively for its role in actin dynamics. In this study, multiple bioinformatics tools were applied cooperatively to the microarray dataset GSE64714 to explore previously unidentified functions of RhoA. Comparative gene expression analysis revealed 545 differentially expressed genes in RhoA-null cells versus controls. Gene set enrichment analysis (GSEA) was conducted with three gene set collections: (1) the hallmark, (2) the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway, and (3) the Gene Ontology Biological Process. GSEA results showed that RhoA is related strongly to diverse pathways: cell cycle/growth, DNA repair, metabolism, keratinization, response to fungus, and vesicular transport. These functions were verified by heatmap analysis, KEGG pathway diagramming, and direct acyclic graphing. The use of multiple gene set collections restricted the leakage of information extracted. However, gene sets from individual collections are heterogenous in gene element composition, number, and the contextual meaning embraced in names. Indeed, there was a limit to deriving functions with high accuracy and reliability simply from gene set names. The comparison of multiple gene set collections showed that although the gene sets had similar names, the gene elements were extremely heterogeneous. Thus, the type of collection chosen and the analytical context influence the interpretation of GSEA results. Nonetheless, the analyses of multiple collections made it possible to derive robust and consistent function identifications. This study confirmed several well-described roles of RhoA and revealed less explored functions, suggesting future research directions.

• 한국인터넷방송통신학회논문지
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• 제20권5호
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• pp.25-30
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• 2020

최근 차세대 이동통신 시스템에 적용하기 위하여 비직교 다중화 (Non-orthogonal multiple access, NOMA) 방식이 많은 주목을 받고 있다. 그런데 NOMA 시스템에서는 동일한 통신자원에 많은 사용자를 중첩하므로 필수적으로 사용자 간섭이 존재하게 된다. 그동안 사용자 간섭을 해석하기 위하여 대표적으로 근사 백색잡음 방식과 랜덤변수 방식의 두 가지 방식을 사용해 왔다. 본 논문에서는 이 두 가지 방법을 NOMA 시스템의 상향 링크에 적용하여 사용자의 오수신률을 각각 유도하고 두 가지 방식의 결과를 서로 비교하였다. 송신전력에 따른 오수신률, 거리에 따른 오수신률, 그리고 전력할당에 따른 오수신률의 수치적인 결과를 각각 비교하였다. 비록 두 가지 방식에서 유도한 수식 표현은 서로 다르지만, 수치적인 예에서는 서로 동일한 결과를 얻었다. 따라서 본 논문의 결과는 NOMA 시스템을 해석하는데 두 가지 방식 모두 적용이 가능하다는 것을 보여주었다.

• 사상체질의학회지
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• 제15권3호
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• pp.204-215
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• 2003

Objectives : This paper was for studying the features of sleep according to Sasang Constitution and to be helpful to make a diagnosis Sasang Constitution. Using the result of this study, it will be helpful to diagnose a Sasang constitution. Methods : There were 610 patients(258 men, 352 women) who answered questionnaire and were diagnosed by the Sasang Constitution Specialist at Constitutional Clinic of Dongguk Bundang Oriental Hospital. Using the response of questionnaire and several statistical techniques such as homogeneity test and multiple comparison, we tried to find the characteristics of each constitution depending on its sleep behaviors. 3. Results : As a result of the analysis of questionnaire, Soeumin has many dreams in comparison with other constitution(p<0.01). Taeumin and Soyangin have a few dream in comparison with Soeumin(p<0.01). Taeyangin has a characteristic that 'he is not drowsy comparatively, he awakes easily, he is not drowsy if it is cold, he is not drowsy and has many dreams if he has many stress.(p<0.01) Taeumin has a characteristics that 'he has a few dream in ordinary times'(p<0.01).