• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.16 no.9
• /
• pp.862-876
• /
• 1991

In this theses, the procedure for finding the equivalent immittance of an n-line coupled structures is presented in terms of the normal mode parameters of the n-line coupled system. The above generalized equations can be applied to the various Coupled structures including directional couplers, DC blocks, bandpass/band elimination filters, and various other uniformly coupled filters. The design equations are based on a simplified TEM(Quasi TEM) mode. The obtained results and the definition of the scattering parameters for a general coupled line four port with arbitrary terminations are used to present the procedure to determine the optimum physical dimensions matching the given load impedances connected to input, output port. Multiple coupled rnicrostrip two-port with three lines circuit designed shows little discrepancy between the conventional method and this one. Four port with five lines were fabricated on teflon substrate($e$r=2.55) with its thickness h=l.588mm designed at the center frequency, 4 GHz. Their measured results are fairly close to the ones by computation.

• Asian Pacific Journal of Cancer Prevention
• /
• v.14 no.2
• /
• pp.1023-1026
• /
• 2013

Cervical cancer is the most important female gynecological cancer, the second leading cause of cancer mortality in women worldwide and the second most common cancer in Thai women. The major cause of cervical cancer is persistent infection of human papillomavirus (HPV), leading to abnormal epithelial lesions, with progression to precancerous and invasive cancer. This study was conducted to investigate the frequency and type distribution of HPV in Thai women who had abnormal cytology. HPV detection from FFPE confirmed abnormal of high grade cervical intraepithelial lesions were for SPF-10-Innogenic Line Probe Assay. HPV-positivity was detected in 320/355 cases (90.14%) and HPV-negativity in 35/355 (9.86%). HPV-positive was found 147/320 cases (41.4%) of single infection, whereas 173/320 cases (48.7%) showed the multiple HPV infection. The most common seven types were HPV-16, -52, -18, -11, -51, -31 and -33, in that order. HPV 16 and 18, the important oncogenic HPV type, were observed in 64.8% of HSIL cases. Interestingly, a high proportion of multiple infections was found in this study and more than ten types could be detected in one case. Therefore, HPV infection screening program in women is essential, particularly in Thailand. Effective primary and secondary prevention campaigns that reinforce HPV screening for HPV detection and typing may be decrease the incidence and mortality of cervical cancer in the future and may lead to significantly improve the quality of life in Thai women.

• Journal of KIISE:Databases
• /
• v.30 no.2
• /
• pp.209-224
• /
• 2003

Recent development of electronic commerce enables the use of Electronic Stock Trading Systems(ESTS) to be expanded. In ESTS, information with various sensitivity levels is shared by multiple users with mutually different clearance levels. Therefore, it is necessary to use Multilevel Secure Database Management Systems(MLS/DBMSs) in controlling concurrent execution among multiple transactions. In ESTS, not only analytical OLAP transactions, but also mission critical OLTP transactions are executed concurrently, which causes it difficult to adapt traditional secure transaction management schemes to ESTS environments. In this paper, we propose Secure One Snapshot(SOS) protocol that is devised for Secure Transaction Management in ESTS. By maintaining additional one snapshot as well as working database SOS blocks covert-channel efficiently, enables various real-time transaction management schemes to be adapted with ease, and reduces the length of waiting queue being managed to maintain freshness of data by utilizing the characteristics of less strict correctness criteria. In this paper, we introduce the process of SOS protocol with some examples, and then analyze correctness of devised protocol.

• Genomics & Informatics
• /
• v.7 no.4
• /
• pp.195-202
• /
• 2009

BIRC5 (Survivin) belongs to the inhibitor of apoptosis gene family. The BIRC5 protein inhibits caspases and consequently blocks apoptosis. Thus, BIRC5 contributes to the progression of cancer allowing for continued cell proliferation and survival. In this study, we identified eight sequence variants of BIRC5 through direct DNA sequencing. Among the eight single nucleotide polymorphisms (SNPs), six common variants with frequencies higher than 0.05 were selected for larger-scale genotyping (n=1,066). Results of the study did not show any association between the promoter region polymorphisms and the clearance of hepatitis B virus (HBV) infection and hepatocellular carcinoma (HCC) occurrence. This is in line with a previous study in which polymorphisms in the promoter region does not influence the function of BIRC5. Initially, we were able to detect a signal with the ＋9194A>G, which disappeared after multiple corrections but led to a change in amino acid. Similarly, we were also able to detect an association signal between two haplotypes (haplotype-2 and haplotype-5) on the onset age of HCC and/or HCC occurrence, but the signals also disappeared after multiple corrections. As a result, we concluded that there was no association between BIRC5 polymorphisms and the clearance HBV infection and/or HCC occurrence. However, our results might useful to future studies.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2009.10a
• /
• pp.553-557
• /
• 2009

USS(Ubiquitous Smart Space) give services, that fit in with customer's goal, by cognizing various situations that happens in a space and cooperating autonomously objects or services in a space. In USS, U-Safety is a system that cognizes more exact situations with multiple sensors in USS, deals with this and take proper actions. When men reason on situations objectively, it is most ideal that image data among collected data with used various sensors in U-Safety. A senter collects a lot of image data from image input devices equipped in various points and work a multiple situation cognition and inference that are based on this. So, senters spend many resources for processing massive data. This paper proposes hierarchical image processing method that does the first situation cognization in image input devices, blocks only points that situation cognization possibility is high among a total image, and transfers to senters. It improves the efficiency of smooth situation cognization by reducing resources that a senter spends on image processing. So, it reduces proportion of image data in U-Safety.

• Journal of Microbiology and Biotechnology
• /
• v.32 no.6
• /
• pp.816-823
• /
• 2022

The rapid spread of superbugs leads to the escalation of infectious diseases, which threatens public health. Endolysins derived from bacteriophages are spotlighted as promising alternative antibiotics against multi-drug resistant bacteria. In this study, we isolated and characterized the novel Salmonella typhimurium phage PBST08. Bioinformatics analysis of the PBST08 genome revealed putative endolysin ST01 with a lysozyme-like domain. Since the lytic activity of the purified ST01 was minor, probably owing to the outer membrane, which blocks accessibility to peptidoglycan, antimicrobial peptide cecropin A (CecA) was fused to the N-terminus of ST01 to disrupt the outer membrane. The resulting CecA::ST01 has been shown to have increased bactericidal activity against gram-negative pathogens including Pseudomonas aeruginosa, Klebsiella pneumoniae, Acinetobacter baumannii, Escherichia coli, and Enterobacter cloacae and the most affected target was A. baumannii. In the presence of 0.25 µM CecA::ST01, A. baumannii ATCC 17978 strain was completely killed and CCARM 12026 strain was wiped out by 0.5 µM CecA::ST01, which is a clinical isolate of A. baumannii and resistant to multiple drugs including carbapenem. Moreover, the larvae of Galleria mellonella could be rescued up to 58% or 49% by the administration of CecA::ST01 upon infection by A. baumannii 17978 or CCARM 12026 strain. Finally, the antibacterial activity of CecA::ST01 was verified using 31 strains of five gram-negative pathogens by evaluation of minimal inhibitory concentration. Thus, the results indicate that a fusion of antimicrobial peptide to endolysin can enhance antibacterial activity and the spectrum of endolysin where multi-drug resistant gram-negative pathogens can be efficiently controlled.

• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 2003.06a
• /
• pp.533-537
• /
• 2003

Compared to sintered polycrystalline diamond (PCD), the deposited thin film diamond has a great advantage on the fabrication of cutting tools with complex geometries such as drills. Because of high performance in high speed machining non-ferrous difficult-to-cut materials in the field of automobiles industry, aeronautics and astronautics industry, diamond-coated drills find large potentialities in commercial applications. However, the poor adhesion of the diamond film on the substrate and high surface roughness of the drill flute adversely affect the tool lift and machining quality and they become the main technical barriers for the successful development and commercialization of diamond-coated drills. In this paper, diamond thin films were deposited on the commercial WC-Co based drills by the electron aided hot filament chemical vapor deposition (EACVD). A new multiple coating technology based on changing gas pressure in different process stages was developed. The large triangular faceted diamond grains may have great contribution to the adhesive strength between the film and the substrate, and the overlapping ball like blocks consisted of nanometer sized diamond crystals may contribute much to the very low roughness of diamond film. Adhesive strength and quality of diamond film were evaluated by scanning electron microscope (SEM), atomic force microscope (AFM), Raman spectrum and drilling experiments. The ring-block tribological experiments were also conducted and the results revealed that the friction coefficient increased with the surface roughness of the diamond film. From a practical viewpoint, the cutting performances of diamond-coated drills were studied by drilling the SiC particles reinforced aluminum-matrix composite. The good adhesive strength and low surface roughness of flute were proved to be beneficial to the good chip evacuation and the decrease of thrust and consequently led to a prolonged tool lift and an improved machining quality. The wear mechanism of diamond-coated drills is the abrasive mechanical attrition.

• Journal of the Korean Applied Science and Technology
• /
• v.37 no.6
• /
• pp.1517-1527
• /
• 2020

This study is about the UV protection effect and water resistance of a multiple emulsion (W/O/W) sunblock cream applied with emotional engineering and reports an actual industrial case. Multiple emulsion system of sunblock cream has the characteristics of changing to a W/O type that is soft and moist when applied, and has excellent water resistance after absorption. Multiple emulsion cream is a highly functional sunblock cream that has both moisture and water resistance. It is a stable milky white cream with a viscosity of 36,000 cps. The organic sunscreen used for the sunscreen was ethylhexylmethoxycinnamate and bisethylhexyloxyphenolmethoxyphenyltriazine. Hexagonal zinc oxide and titanium dioxide that block both UVB and UVA were used. As a result of measuring the UV protection effect by the in-vitro method, the UV protection effect (SPF) is 78.9 for multiple emulsion cream, 76.7 for W/O cream, and 71.3 for O/W cream. It was found that the blocking effect was different. This obtained the highest effect value in the multiple emulsion. As a clinical (in-vivo) result of the UV protection effect, the SPF value representing the UV protection effect of the sunblock cream developed with a multiple emulsion system was 85.7, and the PA-value that blocks the UVA area was 26.5, and ++++. It was found that it has a corresponding high blocking effect. As a result of the water resistance test, the W/O/W formulation had a high waterproofing resistance of 93.8% even after 4 hours, W/O had 75.4%, and O/W had a low water resistance of 25.3%. In the results of the HUT test, it was found in the order of multiple emulsion sun block cream > hydrophilic cream > lipophilic cream. Based on the research results of this multiple emulsion, it is expected to be highly active as a sunblock cream dedicated to outdoor activities by improving the feeling of use, UV protection index, and water resistance. Therefore, in this study, a multiple emulsion system of sunblock cream is developed and has a characteristic that changes to a W/O type that has a soft and moist feeling when applied, and has excellent water resistance after absorption.

• Journal of the Korean housing association
• /
• v.18 no.3
• /
• pp.125-136
• /
• 2007

To improve the environment of individual residential area, the uniform development of multiple dwellings through site should be avoided. As an alternative to a large scale development of the currently popular high-density and high-rise apartment buildings, which disintegrates and destroys existing communities, a new residential type that is applicable to the individual residential area should be developed. From the new residential type, even for short history of Korea of modem urban residence, a new concept of residence can be formed, changing from the concept of a temporary staying place to the concept of a stable residing place. Also, a gradual improvement that transcends time can be expected, and the present and past appearances can co-exist. This study was conducted to suggest a new residential type with unit blocks that can improve the physical structure of existing individual residential area without destroying the structure. That is, among the factors that comprise the individual residential area, this study will focus on the unit block with a medium role between a site and a mega-block, and will suggest a new concept of residential unit in order not to destroy its physical structure. The physical characteristics of the unit block will also be analyzed.

• Journal of the Institute of Electronics Engineers of Korea SD
• /
• v.46 no.9
• /
• pp.14-24
• /
• 2009

Memory cell array and peripheral circuits are designed for system on panel style frame buffer. Moreover, a parallel test methodology to test multiple blocks of memory cells is proposed to overcome low yield of system on panel processing technologies. It is capable of faster fault detection compared to conventional memory tests and also applicable to the tests of various embedded memories and conventional SRAMs. The various patterns of conventional test vectors can be used to enhance fault coverage. The proposed testing method is also applicable to hierarchical bit line and divided word line, one of design trends of recent memory architectures.