• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.20 no.1
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• pp.14-21
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• 2017

Pediatric onset Crohn's disease (CD) tends to have complicated behavior (stricture or penetration) than elderly onset CD at diagnosis. Considering the longer duration of the disease in pediatric patients, the accumulative chance of surgical treatment is higher than in adult onset CD patients. Possible operative indications include perianal CD, intestinal stricture or obstruction, abdominal abscess or fistula, intestinal hemorrhage, neoplastic changes and medically untreatable inflammation. Growth retardation is an operative indication only for pediatric patients. Surgery can affect a patient's clinical course, especially for pediatric CD patient who are growing physically and mentally, so the decision should be made by careful consideration of several factors. The complex and diverse clinical conditions hinder development of a systemized treatment algorithm. Therefore, timing of surgery in pediatric CD patients should be determined with individualized approach by an experienced and well organized multidisciplinary inflammatory bowel disease team. Best long-term outcomes will require proactive post-operative monitoring and therapeutic modifications according to the conditions.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.8 no.2
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• pp.225-231
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• 1997

The persistent and recurrent dysphonia after microlaryngeal surgery was noted in tweleve patients. We reviewed the results of laryngostroboscopy, psychoacoustic evaluation, aerodynamic study and acoustic analysis according to the treatment modality. The causes of persistent dysphonia were attributed to vocal cord scarring, recurrent mass lesion, residual mass lesion, persistent inflammation, and hyperfunctional voice disorder. We noticed the better vocal function in the group treated with voice therapy or surgical therapy than the group treated with voice rest and medication. Therefore, we concluded that vocal function can be improved with the use of active, multidisciplinary approach which includes voice therapy, medical treatment and selected surgical resection according to the laryngeal lesions.

• Archives of design research
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• v.20 no.2 s.70
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• pp.53-64
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• 2007

Web development has multidisciplinary features involving diverse team members. Owing to the diverse backgrounds, however, there may be communication problems among web team members, especially between designers and programmers. Programmers often use a graphical modeling notation to communicate their designs. The graphical modeling concepts can also be helpful to designers, but most designers generally find graphical modeling notations hard to understand. We, therefore, propose an interactive computer-aided collaborative web design system including revised web graphical model notations to improve communication between web designers and programmers. We have designed and implemented a computational prototype to validate the approach and illustrate how the prototype works using concrete examples.

• Journal of KIBIM
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• v.5 no.1
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• pp.16-24
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• 2015

The kinetic façade system is an interactive building envelope which is adaptive to environmental condition by transforming the behaviour of its components. The design process of kinetic façade system calls for a novel approach. It needs to support designers to adopt technologies from multidisciplinary fields such as physical computing and robotics. In this paper, prototyping method is introduced as a useful technique for implementing kinetic façade systems. In order to incorporate prototyping method into architectural design process, two aspects are investigated in digital design studio: (1) The interactions between digital and analogue environments (2) The role of traditional design tools. Furthermore, the role of BIM is investigated by analyzing two aspects.

• Journal of Periodontal and Implant Science
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• v.38 no.sup2
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• pp.405-412
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• 2008

Purpose: Pathologic tooth migration (PTM) commonly occurs in the anterior region and is associated with periodontal disease. The treatment of PTM of anterior teeth can be complex and time consuming, and a multidisciplinary approach is often required. Materials and Methods: The patient was a 38-year-old woman with a chief complaint of saving and realigning her elongated maxillary left central incisor. This paper describes the successful combined periodontal regenerative (guided tissue regeneration) and prosthetic treatment and a 2-year follow-up of maxillary central incisor with pathologic tooth migration, deep intrabony defect, and poor prognosis. Results: The right maxillary central incisor was restored by laminate veneer and the left by all-ceramic crown. The patient had no pain and discomfort and was satisfied with the outcomes of her treatment for 2 years. She has maintained her recall program at the Department of Periodontology at 3 months interval. Conclusion: The key step in the successful treatment of PTM in anterior region is to obtain a high level of cooperation from the patient. Maintenance of the treatment result of PTM is dependent on the continuous preservation of periodontal health.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2003.05a
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• pp.1020-1025
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• 2003

A successful design approach for noise barriers should be multidisciplinary because noise reduction goals influence both acoustical and non-acoustical considerations, such as maintenance, safety, physical construction, cost and visual impact These various barrier design options are closely related with barrier dimensions. In this study, we have proposed an optimal design method of noise barriers using simulated annealing algorithm, providing a barrier having the smallest dimension and achieving the specified noise reduction at a receiver region exposed to the industry and infrastructures, to help a successful barrier design.

• The Journal of the Korean dental association
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• v.57 no.11
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• pp.679-688
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• 2019

A 8-year-old patient presented with a crown-root fracture of the maxillary right central incisor with an oblique subgingival fracture line. A multidisciplinary treatment approach including endodontic treatment, surgical extraction and intraalveolar repositioning was used to gain sufficient crown length of the fractured maxillary incisor. The coronally repositioned maxillary right central incisor was stabilized by a resin wire splint. Apexification using MTA was performed. Resin core and direct resin restoration(Cl IV) on fractured teeth was built up. Clinical and radiographic follow-up of the maxillary right central incisor after 36 months showed no signs of root resorption or pathology and acceptable aesthetics and functions were maintained. Surgical extrusion can be considered as a good treatment modality for young patients.

• BMB Reports
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• v.48 no.10
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• pp.541-548
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• 2015

Cardiomyopathy is an inherited or acquired disease of the myocardium, which can result in severe ventricular dysfunction. Mitochondrial dysfunction is involved in the pathological process of cardiomyopathy. Many dysfunctions in cardiac mitochondria are consequences of mutations in nuclear or mitochondrial DNA followed by alterations in transcriptional regulation, mitochondrial protein function, and mitochondrial dynamics and energetics, presenting with associated multisystem mitochondrial disorders. To ensure correct diagnosis and optimal management of mitochondrial dysfunction in cardiomyopathy caused by multiple pathogenesis, multidisciplinary approaches are required, and to integrate between clinical and basic sciences, ideal translational models are needed. In this review, we will focus on experimental models to provide insights into basic mitochondrial physiology and detailed underlying mechanisms of cardiomyopathy and current mitochondria-targeted therapies for cardiomyopathy.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2011.05a
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• pp.181-184
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• 2011

The earlier studies which are related to conflict management for urban regeneration project were based on limited case-studies on a specific phase. In addition, those studies did not considered a multidisciplinary approach for critical factor of conflict occurrence. In this reason, to establish a practical management or a policy is limited. In this paper, 'Good communication and information sharing' and 'Cooperativeness of stakeholders on project' are defined by critical factors for minimization of conflict between stakeholders. Furthermore we analysis the influence of those factors to minimization of conflict using path-analysis. This paper contributes to increase the efficiency of conflict management through understanding influence of each factors.

• Economic and Environmental Geology
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• v.21 no.3
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• pp.319-329
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• 1988

As a factor which can help to understand the genesis of (mata) sedimentary and/or hydrothermal uranium depisits, an interpretation of the role of organic matter associated with uranium mineralization, was attempted with the literature published up to the end of 1986. Laboratory studies, in which diageneis and metamorphism are artificially simulated, can help to elucidate how uranium with particular organic materials are formed and destroyed. Similarly, research involving a variety of techniques is needed to characterize both the soluble organic extracts (bitumen) and the insoluble organic matter (kerogen), separated from uranium ores and associated rocks. In the presence of clay minerals and amorphous oxy-hydroxde minerals, an understanding of the role of organic matter must be prudent and may require the incorporation of multidisciplinary approach (mineralogy, inorganic geochemistry ...).