• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.11A
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• pp.891-897
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• 2009

In the satellite communications, the frequency sharing with other services is important because the service coverage is generally very wide and overlaps with those of other wireless services. This paper introduces a new technique to mitigate interference into the terrestrial stations from the Earth station in the same frequency band by means of band segmentations which are portions of the overall operation frequency band divided by frequency reuse factor. We consider a multi-beam satellite system, where frequency bands are reused in each satellite cell. The terrestrial stations use band segmentations of adjacent satellite cells, and this may decrease the interferences. By this way, the terrestrial and satellite systems can share the same frequency bands efficiently. The simulation is performed at frequency reuse factors, seven and three. The simulation results show that the proposed method can highly reduce the interference level to -168 dBW or -163 dBW depending on the considered frequency reuse factor from -117 dBW at the 90% link availability.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.9 no.1
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• pp.120-131
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• 2016

In this paper, a 512b MTP memory IP is designed by using MTP memory cells which are written by the FN (Fowler-Nordheim) tunneling method with only MV (medium voltage) devices of 5V which uses the back-gate bias, that is VNN (negative voltage). The used MTP cell consists of a CG (control gate) capacitor, a TG (tunnel gate) transistor, and a select transistor. To reduce the size of the MTP memory cell, just two PWs (P-wells) are used: one for the TG and the select transistors; and the other for the CG capacitor. In addition, just one DNW (deep N-well) is used for the entire 512b memory cell array. VPP and VNN generators supplying pumping voltages of ${\pm}8V$ which are insensitive to PVT variations since VPP and VNN level detectors are designed by a regulated voltage, V1V (=1V), provided by a BGR voltage generator.

• Korean Journal of Materials Research
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• v.19 no.1
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• pp.50-53
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• 2009

Multi-walled carbon nanotubes (MWNTs) were synthesized on different substrates (bare Si and $SiO_2$/Si substrate) to investigate dye-sensitized solar cell (DSSC) applications as counter electrode materials. The synthesis of MWNTs samples used identical conditions of a Fe catalyst created by thermal chemical vapor deposition at $900^{\circ}C$. It was found that the diameter of the MWNTs on the Si substrate sample is approximately $5{\sim}10nm$ larger than that of a $SiO_2$/Si substrate sample. Moreover, MWNTs on a Si substrate sample were well-crystallized in terms of their Raman spectrum. In addition, the MWNTs on Si substrate sample show an enhanced redox reaction, as observed through a smaller interface resistance and faster reaction rates in the EIS spectrum. The results show that DSSCs with a MWNT counter electrode on a bare Si substrate sample demonstrate energy conversion efficiency in excess of 1.4 %.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.11 no.10
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• pp.1924-1929
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• 2007

Nowadays, a lot of related data obtained from these research could be given a new present meaning to accomplish the original purpose of the whole research as a human project. The method of tumor classification based on microarray could contribute to being accurate tumor classification by finding differently expressing gene pattern statistically according to a tumor type. Therefore, the process to select a closely related informative gene with a particular tumor classification to classify tumor using present microarray technology with effect is essential. In this thesis, we used cDNA microarrays of 3840 genes obtained from neuronal differentiation experiment of cortical stem cells on white mouse with cancer, constructed accurate tumor classification model by extracting informative gene list through normalization separately and then did performance estimation by analyzing and comparing each of the experiment results. Result classifying Multi-Perceptron classifier for selected genes using Pearson correlation coefficient represented the accuracy of 95.6%.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.11 no.8
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• pp.1574-1581
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• 2007

DVB-H (Digital Video Broadcasting for Handhold) is a new standard, currently being developed for a portable digital broadcasting, which enhance the multimedia broadcasting service in the Euroapean standard DVB-T (DVB-Terrestrial). Seamless mobility and power saving are essential requirements in the DVB-H system. To support seamless mobility, DVB-H system should provides seamless handover for mobile stations in the MFN (multi frequency network). For seamless handover, the receiver should monitor neighboring cells and it increases the power consumption. And so, power efficient sell searching algorithm for seamless handover is required. In this paper, we propose hypothesis feeling based handover algorithm to enhance the power efficiency by using the fast cell searching, and analyze the performance of handover schemes through the numerical evaluation and simulation.

• Journal of the Korea Society of Computer and Information
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• v.11 no.3
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• pp.1-10
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• 2006

It is widely accepted that the coverage with high user densities can only be achieved with small cell such as micro- and pico-cell. The smaller cell size causes frequent handovers between cells and a decrease in the permissible handover Processing delay. This may result in the handover failure. in addition to the loss of some Packets during the handover. In these cases. re-transmission is needed in order to compensate errors, which triggers a rapid degradation of throughput. In this paper, we propose a new handover scheme in the next generation mobile communication systems, in which the handover setup process is done in advance before a handover request by predicting the handover cell based on mobile terminal's current position and moving direction. Simulation is focused on the handover failure rate and Packet loss rate. The simulation results show that our proposed method provides a better performance than the conventional method.

• BMB Reports
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• v.51 no.12
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• pp.630-635
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• 2018

C-X-C motif chemokine ligand 2 (CXCL2) is a small secreted protein that exhibits a structure similar to the proangiogenic subgroup of the CXC chemokine family. Recently, accumulating evidence suggests that chemokines play a pivotal role in cancer progression and carcinogenesis. We examined the expression levels of 7 types of $ELR^+$ CXCLs messenger RNA (mRNA) in 264 clinical samples. We found that CXCL2 expression was stably down-regulated in 94% of hepatocellular carcinoma (HCC) specimens compared with paired adjacent normal liver tissues and some HCC cell lines. Moreover, CXCL2 overexpression profoundly attenuated HCC cell proliferation and growth and induced apoptosis in vitro. In animal studies, we found that overexpressing CXCL2 by lentivirus also apparently inhibited the size and weight of subcutaneous tumours in nude mice. Furthermore, we demonstrated that CXCL2 induced HCC cell apoptosis via both nuclear and mitochondrial apoptosis pathways. Our results indicate that CXCL2 negatively regulates the cell cycle in HCC cells via the ERK1/2 signalling pathway. These results provide new insights into HCC and may ultimately lead to the discovery of innovative therapeutic approaches of HCC.

• Laboraroty Animal Research
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• v.34 no.4
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• pp.279-287
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• 2018

Placenta specific 8 (PLAC8, also known as ONZIN) is a multi-functional protein that is highly expressed in the intestine, lung, spleen, and innate immune cells, and is involved in various diseases, including cancers, obesity, and innate immune deficiency. Here, we generated a Plac8 knockout mouse using the CRISPR/Cas9 system. The Cas9 mRNA and two single guide RNAs targeting a region near the translation start codon at Plac8 exon 2 were microinjected into mouse zygotes. This successfully eliminated the conventional translation start site, as confirmed by Sanger sequencing and PCR genotyping analysis. Unlike the previous Plac8 deficient models displaying increased adipose tissue and body weights, our male Plac8 knockout mice showed rather lower body weight than sex-matched littermate controls, though the only difference between these two mouse models is genetic context. Differently from the previously constructed embryonic stem cell-derived Plac8 knockout mouse that contains a neomycin resistance cassette, this knockout mouse model is free from a negative selection marker or other external insertions, which will be useful in future studies aimed at elucidating the multi-functional and physiological roles of PLAC8 in various diseases, without interference from exogenous foreign DNA.

• Journal of IKEEE
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• v.26 no.4
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• pp.714-721
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• 2022

A phase-locked loop (PLL)-based frequency synthesizer is proposed for a system on a chip (SoC) using multi-frequency clock signals. The proposed PLL-based frequency synthesizer consists of a charge pump PLL which is implemented by a phase frequency detector (PFD), a charge pump (CP), a loop filter, a voltage controlled oscillator (VCO), and a frequency divider, and an edge combiner. The PLL outputs a 12-phase clock by a VCO using six differential delay cells. The edge combiner synthesizes the frequency of the output clock through edge combining and frequency division of the 12-phase output clock of the PLL. The proposed PLL-based frequency synthesizer is designed using a 55-nm CMOS process with a 1.2-V supply voltage. It outputs three clocks with frequencies of 166 MHz, 83 MHz and 124.5MHz for a reference clock with a frequency of 20.75 MHz.

• Membrane and Water Treatment
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• v.14 no.1
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• pp.35-45
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• 2023

Biofilms significantly affect the performance of wastewater treatment processes in which biodegradability of numerous microorganisms are actively involved, and various technologies have been applied to secure microbial biofilms. Understanding changes in biofilm characteristics by regulating expression of signaling molecules is important to control and regulate biofilms in membrane bioreactor, i.e., biofouling. This study investigated effects of addition of acyl-homoserine lactones (AHL) as a controllable factor for the microbial signaling system on biofilm formation of Pseudomonas aeruginosa PAO1 and multiple strains in membrane bioreactor. The addition of three AHL, i.e., C4-, C6-, and C8-HSL, at a concentration of 200 ㎍/L, enhanced the formation of the PAO1 biofilm and the degree of increases in the biofilm formation of PAO1 were 70.2%, 76.6%, and 72.9%, respectively. The improvement of biofilm formation of individual strains by C4-HSL was an average of 68%, and the microbial consortia increased by approximately 52.1% in the presence of 200 ㎍/L C4-HSL. CLSM images showed that more bacterial cells were present on the membrane surface after the AHL application. In the COMSTAT results, biomass and thickness were increased up to 2.2 times (PAO1) and 1.6 times (multi-strains) by C4-HSL. This study clearly showed that biofilm formation was increased by the application of AHL to individual strain groups, including PAO1 and microbial consortia, and significant increases were observed when 50 or 100 ㎍/L AHL was administered. This suggests that AHL application can improve the biofilm formation of microorganisms, which could yield an enhancement in efficiency of biofilm control, such as in various biofilm reactors including membrane bioreactor and bioflocculent systems in water/wastewater treatment processes.