• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2009.04a
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• pp.342-350
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• 2009

Fuel cells convert a fuel together with oxygen in a highly efficient electrochemical reaction to electricity and water. Since the electrochemical reaction in the fuel cell stack dose not generate any noise, Fuel cell systems are expected to operated much quieter than combustion engines. However, the tonal noise and the broad band noise caused by a centrifugal compressor and an electric motor cause which is required to feed the ambient air to the cathode of the fuel cell stack with high pressure. In this study, the multi-camber perforated muffler is used to reduce noise. We propose optimized muffler model using an axiomatic design method that optimizes the parameters of perforated muffler while keeping the volume of muffler minimized.

• Bulletin of the Korean Chemical Society
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• v.35 no.8
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• pp.2317-2325
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• 2014

P-glycoprotein (P-gp) is a member of the ATP-Binding Cassette transporter superfamily and mediates transmembrane efflux of many drugs. Since it is involved in multi-drug resistance activity in various cancer cells, the development of P-gp inhibitor is one of the major concerns in anticancer therapy. Human P-gp protein has at least two "functional" drug binding sites that are called "H" site and "R" site, hence it has multi-binding-specificities. Though the amino acid residues that constitute in drug binding pockets have been proposed by previous experimental evidences, the shapes and the binding poses are not revealed clearly yet. In this study, human P-gp structure was built by homology modeling with available crystal structure of mouse P-gp as a template and docking simulations were performed with inhibitors such as verapamil, hoechst33342, and rhodamine123 to construct the interaction between human P-gp and its inhibitors. The docking simulations were performed 500 times for each inhibitor, and then the interaction frequency of the amino acids at the binding poses was analyzed. With the analysis results, we proposed highly contributing residues that constitute binding pockets of the human P-gp for the inhibitors. Using the highly contributing residues, we proposed the locations and the shapes of verapamil binding site and "R" site, and suggested the possible position of "H" site.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2005.11a
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• pp.297-298
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• 2005

We have fabricated twisted nematic (TN) liquid crystal cells doped by carbon nanotubes (CNTs) with different CNT wt. %. With a minute amount doping, multi-walled CNTs did not perturb the liquid crystal orientations at the off- and on-state. The hysteresis studies of voltage-dependent capacitance (V-C) under the influence of electric field generated by ac and dc voltage show that the residual do, which is tightly related to image sticking problem in liquid crystal displays, is greatly reduced due to ion trapping by CNTs. Also, the V-C hysteresis shows dependency of capacitance on concentration of multi-walled CNTs.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.37B no.10
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• pp.921-928
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• 2012

In this paper, we propose a novel interference alignment transceiver for multi-cell MIMO downlink channels with arbitrary number of cells and users per cell. We design the receive beamformer to align the interference from undesired base stations to the effective inter-cell interference (ICI) channels. Subsequently, we design the transmit precoder which can nulllify the interference from the corresponding base station. The proposed transceiver design can attain the degrees of freedom (DOF) equal to the number of streams per user. Accordingly, we investigate conditions for the antenna configuration. From numerical results, we confirm that the proposed transceiver design can achieve higher DOF than the conventional scheme under equal antenna configuration.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.3A
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• pp.238-244
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• 2010

We propose a user selection method in multi-cell multiuser uplink system with the subspace interference alignment to maintain the high sum-rate capacity. The proposed method selects users whose interference to adjacent cells are strong and apply the subspace interference alignment to the users. The proposed method provides that the number of users performing the interference alignment reduces and the high total sum-rate is maintained. Simulation results exhibit the proposed method reduces the number of users who would decompose the channel for the subspace interference alignment by 50% when the required sum-rate is 90% of the maximal achievable sum-rate.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.9 no.11
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• pp.4291-4310
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• 2015

This paper investigates the traffic offloading over unlicensed bands for two-tier multi-mode small cell networks. We formulate this problem as a Stackelberg game and apply a hierarchical learning framework to jointly maximize the utilities of both macro base station (MBS) and small base stations (SBSs). During the learning process, the MBS behaves as a leader and the SBSs are followers. A pricing mechanism is adopt by MBS and the price information is broadcasted to all SBSs by MBS firstly, then each SBS competes with other SBSs and takes its best response strategies to appropriately allocate the traffic load in licensed and unlicensed band in the sequel, taking the traffic flow payment charged by MBS into consideration. Then, we present a hierarchical Q-learning algorithm (HQL) to discover the Stackelberg equilibrium. Additionally, if some extra information can be obtained via feedback, we propose an improved hierarchical Q-learning algorithm (IHQL) to speed up the SBSs' learning process. Last but not the least, the convergence performance of the proposed two algorithms is analyzed. Numerical experiments are presented to validate the proposed schemes and show the effectiveness.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.2 no.1
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• pp.23-34
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• 2004

To validate the previous conceptual design of cover system, construction of the engineered barrier test facility is completed and the performance tests of the disposal cover system are conducted. The disposal test facility is composed of the multi-purpose working space, the six test cells and the disposal information space for the PR center. The dedicated detection system measures the water content, the temperature, the matric potential of each cover layer and the accumulated water volume of lateral drainage. Short-term experiments on the disposal cover layer using the artificial rainfall system are implemented. The sand drainage layer shows the satisfactory performance as intended in the design stage. The artificial rainfall does not affect the temperature of cover layers. It is investigated that high water infiltration of the artificial rainfall changes the matric potential in each cover layer. This facility is expected to increase the public information about the national radioactive waste disposal program and the effort for the safety of the planned disposal facility.

• Journal of Microbiology and Biotechnology
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• v.15 no.2
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• pp.234-238
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• 2005

Glucose oxidase was immobilized on the carboxylated multi-wall carbon nanotubes (MWNT-COOHs) in the presence of a coulping reagent, 1-ethy1-3-(3-dimethylaminopropy1) carbodiimide. Significant amounts of glucose oxidase were also immobilized on MWNT-COOHs without the coupling reagent. Various conditions for the immobilization of glucose oxidase were optimized. Optimal pH for the maximal activity of the immobilized glucose oxidase shifted to 7 from the optimal pH of 6 for the maximal activity of free enzyme due to the carboxy1 groups on the surface of MWNT-COOHs. An electrode of graphite rod with a diameter of 6 mm was fabricated using the immobilized glucose oxidase. The cyclic voltammetry study of the enzyme electrode revealed that the oxidation of glucose and subsequent transfer of electrons from the oxidation of glucose to the electrode were possible by the immobilized glucose oxidase without a mediator, implying that the enzyme electrode can be utilized for the development of biofuel cells.

• Nuclear Engineering and Technology
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• v.38 no.4
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• pp.327-342
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• 2006

Radiation therapy is an important part of cancer treatment in which cancer patients are treated using high-energy radiation such as x-rays, gamma rays, electrons, protons, and neutrons. Currently, about half of all cancer patients receive radiation treatment during their whole cancer care process. The goal of radiation therapy is to deliver the necessary radiation dose to cancer cells while minimizing dose to surrounding normal tissues. Success of radiation therapy highly relies on how accurately 1) identifies the target and 2) aim radiation beam to the target. Both tasks are strongly dependent of imaging technology and many imaging modalities have been applied for radiation therapy such as CT (Computed Tomography), MRI (Magnetic Resonant Image), and PET (Positron Emission Tomogaphy). Recently, many researchers have given significant amount of effort to develop and improve imaging techniques for radiation therapy to enhance the overall quality of patient care. For example, advances in medical imaging technology have initiated the development of the state of the art radiation therapy techniques such as intensity modulated radiation therapy (IMRT), gated radiation therapy, tomotherapy, and image guided radiation therapy (IGRT). Capability of determining the local tumor volume and location of the tumor has been significantly improved by applying single or multi-modality imaging fur static or dynamic target. The use of multi-modality imaging provides a more reliable tumor volume, eventually leading to a better definitive local control. Image registration technique is essential to fuse two different image modalities and has been In significant improvement. Imaging equipments and their common applications that are in active use and/or under development in radiation therapy are reviewed.

• ETRI Journal
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• v.38 no.6
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• pp.1153-1162
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• 2016

This paper addresses the resource allocation (RA) problem in multi-cell cognitive radio networks. Besides the interference power threshold to limit the interference on primary users PUs caused by cognitive users CUs, a proportional fairness constraint is used to guarantee fairness among multiple cognitive cells and the impact of imperfect spectrum sensing is taken into account. Additional constraints in typical real communication scenarios are also considered-such as a transmission power constraint of the cognitive base stations, unique subcarrier allocation to at most one CU, and others. The resulting RA problem belongs to the class of NP-hard problems. A computationally efficient optimal algorithm cannot therefore be found. Consequently, we propose a suboptimal RA algorithm composed of two modules: a subcarrier allocation module implemented by the immune algorithm, and a power control module using an improved sub-gradient method. To further enhance algorithm performance, these two modules are executed successively, and the sequence is repeated twice. We conduct extensive simulation experiments, which demonstrate that our proposed algorithm outperforms existing algorithms.