• Title/Summary/Keyword: multi function

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Single- and Repeated-dose Toxicities of Acanthopanax senticosus Fermentation Products in Rats (흰쥐에서 가시오가피 발효물의 단회 및 반복투여 독성평가)

  • Cho, Ju-Hyun;Park, In-Jae;Baik, Soon-Ok;Choi, Soo-Young;Choi, Goo-Hee
    • Korean Journal of Food Science and Technology
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    • v.46 no.2
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    • pp.249-255
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    • 2014
  • In this study, the products of Acanthopanax senticosus fermentation were derived from the mycelia of 2 mushrooms, Ganoderma lucidum and Phellinus linteus, to determine their safety in Sprague-Dawley rats. Rats were orally administered the water extracts of A. senticosus fermentation products with G. lucidum (FM-5111) or P. linteus (FM-5131) at dose levels of 0.5, 1.0, or 2.0 g/kg for the single-dose toxicity test and 0.25, 0.5, or 1.0 g/kg for the repeated-dose toxicity test. There were no significant differences in body weight gain, feed intake, or water consumption between control and FM-5111- or FM-5131-treated rats. Hematological and blood biochemistry analysis revealed that none of the investigated parameters were affected by the A. senticosus fermentation products, and no remarkable lesions were observed upon histopathological analysis. We conclude that the A. senticosus fermentation products obtained from mushroom mycelia are safe for long-term administration and could be considered as multi-functional nutrients for the improvement of liver function and immunity.

Design and Implementation of an Agent-based Continuous Double Auction System (에이전트 기반의 연속다중경매 시스템의 설계 및 구현)

  • Kim, Kwang-Soo;Kim, In-Cheol
    • Journal of KIISE:Computing Practices and Letters
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    • v.7 no.6
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    • pp.641-652
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    • 2001
  • Most of current internet auction systems are single auction server program that partly automates the function of the conventional auction house. So these systems do not provide sufficient independence, distribution and parallelism between the functions of the conventional auction house. In these suction systems, only some of suction management facilities are automated by the server program, but still users need to execute a repetitive task to monitor the dynamic progress of a certain auction, decide the proper bid price, and submit the bid. Another problem is that they support only the single auctions such as English suction and Dutch auction, but they do not support the double auctions that are superior to the single auction in terms of speed, efficiency, and the fair distribution of profit. In this paper, we present are design and implement of an agent-based continuous double auction system, called CoDABot, in order to overcome the limitations of current auction systems. CoDABot supports the continuous double auction, provides various bidding agents for users to select, and has been implemented with a multi-agent system to realize more independent, and parallel subsystems.

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DNA Sequence Design using $\varepsilon$ -Multiobjective Evolutionary Algorithm ($\varepsilon$-다중목적함수 진화 알고리즘을 이용한 DNA 서열 디자인)

  • Shin Soo-Yong;Lee In-Hee;Zhang Byoung-Tak
    • Journal of KIISE:Software and Applications
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    • v.32 no.12
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    • pp.1217-1228
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    • 2005
  • Recently, since DNA computing has been widely studied for various applications, DNA sequence design which is the most basic and important step for DNA computing has been highlighted. In previous works, DNA sequence design has been formulated as a multi-objective optimization task, and solved by elitist non-dominated sorting genetic algorithm (NSGA-II). However, NSGA-II needed lots of computational time. Therefore, we use an $\varepsilon$- multiobjective evolutionarv algorithm ($\varepsilon$-MOEA) to overcome the drawbacks of NSGA-II in this paper. To compare the performance of two algorithms in detail, we apply both algorithms to the DTLZ2 benchmark function. $\varepsilon$-MOEA outperformed NSGA-II in both convergence and diversity, $70\%$ and $73\%$ respectively. Especially, $\varepsilon$-MOEA finds optimal solutions using small computational time. Based on these results, we redesign the DNA sequences generated by the previous DNA sequence design tools and the DNA sequences for the 7-travelling salesman problem (TSP). The experimental results show that $\varepsilon$-MOEA outperforms the most cases. Especially, for 7-TSP, $\varepsilon$-MOEA achieves the comparative results two tines faster while finding $22\%$ improved diversity and $92\%$ improved convergence in final solutions using the same time.

Aeroelastic Tailoring of a Forward-Swept Wing Using One-dimensional Beam Analysis (1차원 보 해석을 활용한 전진익 항공기의 복합적층 날개 공력탄성학적 테일러링)

  • Choi, JaeWon;Lim, ByeongUk;Lee, SiHun;Shin, SangJoon
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.48 no.8
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    • pp.555-563
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    • 2020
  • Foward-swept wings are known to possess superior aerodynamic performance compared to the conventional straight wings. However major concerns regarding forward-swept wings include divergence at lower airspeeds which require careful consideration at the design stage. As an endeavor to overcome such drawbacks, aeroelastic tailoring is attempted. In order to find an optimal ply sequence, recursive aeroelastic analyses is conducted and one-dimensional beam analysis coupled with simple aerodynamics is used for the improved computational efficiency and modelling convenience. The analysis used in this paper, DYMORE and analytic formula, both use one-dimensional beam model for the structure. Cross-sectional analysis for multi-cell NACA0015 airfoil section is conducted using VABS and oblique function is used for the sweep angle. Throughout the present aeroelastic tailoring, the maximum divergence speed of 290.2m/s is achieved which is increased by approximately 43% than that for the conventional ply configuration.

A Case Study of Alumni Survey for Evaluation of Engineering Education Outcomes (공학교육 성과 평가를 위한 졸업생 설문조사 사례연구)

  • Hahn Song-Yop;Suh Kyung-Doug
    • Journal of Engineering Education Research
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    • v.5 no.1
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    • pp.34-49
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    • 2002
  • The School of Electrical Engineering and School of Civil, Urban, and Geosystem Engineering of Seoul National University (SNU) have conducted alumni surveys to evaluate the importance and preparedness of the engineering outcomes that are demanded in the industry and to feedback the survey results to the establishment of educational objectives and student capability and the revision of curricula. In this paper, first we analyzed the collected data to see the distributions of the respondents in terms of graduation year, profession, final degree, and so on. Second we evaluated the importance and preparedness of the engineering outcomes and compared them with those obtained at the Department of Mechanical and Aerospace Engineering of UCLA. The above-mentioned three groups gave very similar evaluation of the importance of each item of engineering outcomes, showing that the industry-demanding engineering outcomes are very similar regardless of country or major. Investigating the difference between the importance and preparedness, SNU showed relatively low preparedness compared to UCLA, meaning that SNU is somewhat behind UCLA in engineering education. On the other hand, all the three groups showed considerably poor preparedness in the abilities to function on multi-disciplinary teams and to communicate effectively, indicating that is needed education to strengthen these abilities.

The vegetation analysis of Northern region at Jungnang riverside - Between two bridges of Wallgae 1 and Sangdo - (서울시 중랑천 북부구간 하천변 식생과 식물상 분석 - 월계1교에서 상도교 구간을 대상으로 -)

  • Lee, Sanghwa;Lee, Kyunghee;Jeong, Jongcheol
    • Journal of Environmental Impact Assessment
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    • v.23 no.4
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    • pp.315-322
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    • 2014
  • After the modern industrial revolution, rivers in cities became covered and disappeared due to the pressure to develop them. Likewise, their function which is to serve as the basis of natural ecology system in the cities began to be damaged. This research demonstrated that there are a total of 268 categories when it comes to the list of plants, including 64 families, 179 genera, 230 species, 36 varieties, and 1 subspecies. When the relative abundance of the plants that were found at the target research site was studied, the secondary survey demonstrated Bromus japonicus 22.97, Artemisia princeps var. orientalis 16.76 and Erigeron annuus 15.69 while third survey demonstrated Digitaria ciliaris 26.78, Ambrosia trifida 16.29 and Aster pilosus 14.31. There were 54 species of naturalized plants that appeared. Analysis demonstrated annual plant 23 classification category (43%), perennial 11 classification category (20%), multi-perennation 17 classification category (31%), woody plant 3 classification category (6%) and others. When the naturalized plants that were found at the target research site were analyzed by the place of origin, North America and EU took up 76%, which accounts for 3/4 of the all the naturalized plants. At the target research site, naturalization degree of 5 pertained to 22 classification category (41%), which was the highest, followed by 19 classification category (35%) with naturalization degree of 3, 8 classification category (15%) with naturalization degree of 2 and 5 classification category (9%) with naturalization degree of 4 in the order mentioned. Flora of Jungnangcheon did not manifest any change compared to 10 years ago. Thus, it is necessary to increase of biodiversity efforts to improve SeoulCity's natural environment and cityscape.

A Study on the Identification and Classification of Relation Between Biotechnology Terms Using Semantic Parse Tree Kernel (시맨틱 구문 트리 커널을 이용한 생명공학 분야 전문용어간 관계 식별 및 분류 연구)

  • Choi, Sung-Pil;Jeong, Chang-Hoo;Chun, Hong-Woo;Cho, Hyun-Yang
    • Journal of the Korean Society for Library and Information Science
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    • v.45 no.2
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    • pp.251-275
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    • 2011
  • In this paper, we propose a novel kernel called a semantic parse tree kernel that extends the parse tree kernel previously studied to extract protein-protein interactions(PPIs) and shown prominent results. Among the drawbacks of the existing parse tree kernel is that it could degenerate the overall performance of PPI extraction because the kernel function may produce lower kernel values of two sentences than the actual analogy between them due to the simple comparison mechanisms handling only the superficial aspects of the constituting words. The new kernel can compute the lexical semantic similarity as well as the syntactic analogy between two parse trees of target sentences. In order to calculate the lexical semantic similarity, it incorporates context-based word sense disambiguation producing synsets in WordNet as its outputs, which, in turn, can be transformed into more general ones. In experiments, we introduced two new parameters: tree kernel decay factors, and degrees of abstracting lexical concepts which can accelerate the optimization of PPI extraction performance in addition to the conventional SVM's regularization factor. Through these multi-strategic experiments, we confirmed the pivotal role of the newly applied parameters. Additionally, the experimental results showed that semantic parse tree kernel is superior to the conventional kernels especially in the PPI classification tasks.

Frequency of grammar items for Korean substitution of /u/ for /o/ in the word-final position (어말 위치 /ㅗ/의 /ㅜ/ 대체 현상에 대한 문법 항목별 출현빈도 연구)

  • Yoon, Eunkyung
    • Phonetics and Speech Sciences
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    • v.12 no.1
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    • pp.33-42
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    • 2020
  • This study identified the substitution of /u/ for /o/ (e.g., pyəllo [pyəllu]) in Korean based on the speech corpus as a function of grammar items. Korean /o/ and /u/ share the vowel feature [+rounded], but are distinguished in terms of tongue height. However, researchers have reported that the merger of Korean /o/ and /u/ is in progress, making them indistinguishable. Thus, in this study, the frequency of the phonetic manifestation /u/ of the underlying form of /o/ for each grammar item was calculated in The Korean Corpus of Spontaneous Speech (Seoul Corpus 2015) which is a large corpus from a total of 40 speakers from Seoul or Gyeonggi-do. It was then confirmed that linking endings, particles, and adverbs ending with /o/ in the word-final position were substituted for /u/ approximately 50% of the stimuli, whereas, in nominal items, they were replaced at a frequency of less than 5%. The high rates of substitution were the special particle "-do[du]" (59.6%) and the linking ending "-go[gu]" (43.5%) among high-frequency items. Observing Korean pronunciation in real life provides deep insight into its theoretical implications in terms of speech recognition.

ON THE GALACTIC SPIRAL PATTERNS: STELLAR AND GASEOUS

  • MARTOS MARCO;YANEZ MIGUEL;HERNANDEZ XAVIER;MORENO EDMUNDO;PICHARDO BARBARA
    • Journal of The Korean Astronomical Society
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    • v.37 no.4
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    • pp.199-203
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    • 2004
  • The gas response to a proposed spiral stellar pattern for our Galaxy is presented here as calculated via 2D hydrodynamic calculations utilizing the ZEUS code in the disk plane. The locus is that found by Drimmel (2000) from emission profiles in the K band and at 240 ${\mu}m$. The self-consistency of the stellar spiral pattern was studied in previous work (see Martos et al. 2004). It is a sensitive function of the pattern rotation speed, $\Omega$p, among other parameters which include the mass in the spiral and its pitch angle. Here we further discuss the complex gaseous response found there for plausible values of $\Omega$p in our Galaxy, and argue that its value must be close to $20 km s^{-l}\;kpc^{-1}$ from the strong self-consistency criterion and other recent, independent studies which depend on such parameter. However, other values of $\Omega$p that have been used in the literature are explored to study the gas response to the stellar (K band) 2-armed pattern. For our best fit values, the gaseous response to the 2-armed pattern displayed in the K band is a four-armed pattern with complex features in the interarm regions. This response resembles the optical arms observed in the Milky Way and other galaxies with the smooth underlying two-armed pattern of the old stellar disk populations in our interpretation. The complex gaseous response appears to be related to resonances in stellar orbits. Among them, the 4:1 resonance is paramount for the axisymmetric Galactic model employed, and the set of parameters explored. In the regime seemingly proper to our Galaxy, the spiral forcing appears to be marginally strong in the sense that the 4:1 resonance terminates the stellar pattern, despite its relatively low amplitude. In current work underway, the response for low values of $\Omega$p tends to remove most of the rich structure found for the optimal self-consistent model and the gaseous pattern is ring-like. For higher values than the optimal, more features and a multi-arm structure appears.

Operating Characteristics of a Continuous Two-Stage Bubbling Fluidized-Bed Process (연속식 2단 기포 유동층 공정의 운전특성)

  • Youn, Pil-Sang;Choi, Jeong-Hoo
    • Korean Chemical Engineering Research
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    • v.52 no.1
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    • pp.81-87
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    • 2014
  • Flow characteristics and the operating range of gas velocity was investigated for a two-stage bubbling fluidized-bed (0.1 m-i.d., 1.2 m-high) that had continuous solids feed and discharge. Solids were fed in to the upper fluidized-bed and overflowed into the bed section of the lower fluidized-bed through a standpipe (0.025 m-i.d.). The standpipe was simply a dense solids bed with no mechanical or non-mechanical valves. The solids overflowed the lower bed for discharge. The fluidizing gas was fed to the lower fluidized-bed and the exit gas was also used to fluidize the upper bed. Air was used as fluidizing gas and mixture of coarse (< $1000{\mu}m$ in diameter and $3090kg/m^3$ in apparent density) and fine (< $100{\mu}m$ in diameter and $4400kg/m^3$ in apparent density) particles were used as bed materials. The proportion of fine particles was employed as the experimental variable. The gas velocity of the lower fluidized-bed was defined as collapse velocity in the condition that the standpipe was emptied by upflow gas bypassing from the lower fluidized-bed. It could be used as the maximum operating velocity of the present process. The collapse velocity decreased after an initial increase as the proportion of fine particles increased. The maximum took place at the proportion of fine particles 30%. The trend of the collapse velocity was similar with that of standpipe pressure drop. The collapse velocity was expressed as a function of bulk density of particles and voidage of static bed. It increased with an increase of bulk density, however, decreased with an increase of voidage of static bed.