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Chemical Studies on the Alkaloidal Constituents of Codonopsis lanceolata (더덕의 알칼로이드 성분에 관한 연구)

  • 장영경;김상열;한병훈
    • YAKHAK HOEJI
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    • v.30 no.1
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    • pp.1-7
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    • 1986
  • The alkaloid components in the root of Codonopsis lanceolata were studied. From the ether soluble alkaloid fraction, four $\beta$-carboline alkaloids were isolated in crystalline state by chromatographic purification process; comp. I mp $178^{\circ}$, isolated yield 4.5$\times$$10^{-5}%$, comp. II mp $166^{\circ}$, 6.0$\times$$10^{-5}%$, comp. III mp $164^{\circ}$, 1.8$\times$$10^{-4}%$ and comp. IV mp $197^{\circ}$, 3.5$\times$$10^{-5}%$. They were identified by spectral analysis and by total synthesis as being a new component $N_9$-formylharman, and already known components in other plant 1-carbomethoxy-$\beta$-carboline, perlolyrine and norharman.

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Design of a Format Converter from MPEG-4 Over MPEG-2 TS to MP4 (MPEG-2 TS 상의 MPEG-4 비트스트림으로부터 MP4 파일로의 변환기 설계)

  • 최재영;정제창;동용배
    • Proceedings of the IEEK Conference
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    • 2000.09a
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    • pp.277-280
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    • 2000
  • 본 논문에서는 MPEG-2 시스템 층의 하나인 방송 및 전송을 위한 Transport Stream (TS)상에 MPEG-4 데이터를 구조화하여 MPEG-4 Over MPEG-2 TS 비트스트림을 만드는 방법과 이를 저장 매체 포맷중 하나인 MP4 파일로 변환 설계에 관한 연구이다. MPEG-4는 객체 단위의 부호화 비트스트림으로 구성되어 있기 때문에 이들 객체의 속성을 표현하는 객체기술자, 객체들간의 시공간 관계를 표현하는 장면기술자가 필요하며 또한 모든 객체들간의 복호와 정보와 객체간의 동기화를 위해 여러 가지 기술자들이 필요한데 바로 이런 다양한 MPEG-4 비트스트림을 어떻게 MPEG-TS 규격에 맞게 전송하는가에 초점을 두었다.

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Satellite Distance Learning System Design and Implementation under DVB using MPEG-4 (DVB 환경에서의 MPEG-4를 이용한 위성원격교육 시스템 설계 및 구현)

  • 이봉호;김호겸;이호진
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2001.11b
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    • pp.57-62
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    • 2001
  • 현재 서비스되고 있는 디지털 위성방송(DVB) 서비스의 경우 비디오는 SD급인 MPEG-2 방식을 이용하고 있다. [1] MPEG-2 비디오를 위성을 이용한 원격 교육 서비스에 적용할 경우 해상도 및 데이터량이 보이고자 하는 교육 데이터에 배해 상대적으로 커 비효율적이다. 이를 개선하고 위성을 이용한 원격교육 서비스를 효율적으로 구현하기 위한 MPEG-4 적용 방안 및 구현 기술을 제안한다. MPEG-4 비디오 프로파일은 심플 프로파일을 적용하며 오디오는 G.273.1을 사용하고 MPEG-4 데이터 및 mp4 파일 전송은 DVB 방식의 데이터 방송 규격인 MPE와 Data Carousel을 적용한다. MPEG-4를 이용한 위성 원격교육 서비스에서의 실시간 강의 서비스에 해당하는 라이브 캐스팅 외에 mp4 파일을 이용한 파일 캐스팅 및 비실시간 강의 서비스에 해당하는 mp4 파일의 캐로셀 전송 방안에 대해서 제안 하고자 한다.

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$Mycoplasma$ $pneumoniae$ pneumonia in children

  • Youn, You-Sook;Lee, Kyung-Yil
    • Clinical and Experimental Pediatrics
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    • v.55 no.2
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    • pp.42-47
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    • 2012
  • $Mycoplasma$ $pneumoniae$ (MP), the smallest self-replicating biological system, is a common cause of upper and lower respiratory tract infections, leading to a wide range of pulmonary and extra-pulmonary manifestations. MP pneumonia has been reported in 10 to 40% of cases of community-acquired pneumonia and shows an even higher proportion during epidemics. MP infection is endemic in larger communities of the world with cyclic epidemics every 3 to 7 years. In Korea, 3 to 4-year cycles have been observed from the mid-1980s to present. Although a variety of serologic assays and polymerase chain reaction (PCR) techniques are available for the diagnosis of MP infections, early diagnosis of MP pneumonia is limited by the lack of immunoglobulin (Ig) M antibodies and variable PCR results in the early stages of the infection. Thus, short-term paired IgM serologic tests may be mandatory for an early and definitive diagnosis. MP infection is usually a mild and self-limiting disease without specific treatment, and if needed, macrolides are generally used as a first-choice drug for children. Recently, macrolide-resistant MP strains have been reported worldwide. However, there are few reports of apparent treatment failure, such as progression of pneumonia to acute respiratory distress syndrome despite macrolide treatment. The immunopathogenesis of MP pneumonia is believed to be a hyperimmune reaction of the host to the insults from MP infection, including cytokine overproduction and immune cell activation (T cells). In this context, immunomodulatory treatment (corticosteroids or/and intravenous Ig), in addition to antibiotic treatment, might be considered for patients with severe infection.

Effects of film liners, ethylene scrubber, alcohol releaser and chlorine dioxide on the berry quality during simulated marketing in 'Campbell Early' grapes

  • Kim, Sung-Joo;Choi, Cheol;Ahn, Young-Jik;Lim, Byung-Sun;Chun, Jong-Pil
    • Korean Journal of Agricultural Science
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    • v.47 no.3
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    • pp.415-424
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    • 2020
  • This study investigated the effects of an ethylene scrubber (ES) with a micro-perforated polypropylene (MP-PP, 30 ㎛) or a high density polyethylene (MP-HDPE, 30 ㎛) film liner for the export carton packaging box in 'Campbell Early' grapes. Rachis browning was highest in the untreated group, followed by MP-PP and MP-HDPE for 14 days of simulated marketing at 20℃. The combination treatment of ES with the film liners showed a partial inhibition of the rachis browning regardless of the film liners. The effects of an alcohol releaser (AR) sachet or chlorine dioxide (CD) diffuser co-packaging were also investigated in the 'Campbell Early' grapes packed with the MP-HDPE (40 × 99 pin hole·m-2) film liner. The CD 1 g treatment showed a very limited weight loss of 1.1%, which was significantly lower than the 4.7% of the untreated control after 14 days of simulation marketing at 20℃. The berry shatter was 0.7% for the MP-HDPE + CD 1 g treatment and 1.8% for the MP-HDPE + CD 5 g treatment on the 10th day of the simulated marketing, which was significantly lower than the 8.9% of the control. The stem browning was significant suppressed until the 10th day of the simulated marketing. In particular, the CD 1 g treatment in combination with the MP-HDPE showed a low rachis and pedicel browning index of 2.0, which is 50% and 40% lower than that of the untreated control and the MP-HDPE single treatment, respectively. In addition, the CD 1 g treatment group showed a higher decay reduction effect than the CD 5 g treatment group, which caused high concentration damage.

Comparison of Ablation Performance between Octopus Multipurpose Electrode and Conventional Octopus Electrode

  • Sae-Jin Park;Jae Hyun Kim;Jeong Hee Yoon;Jeong Min Lee
    • Korean Journal of Radiology
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    • v.24 no.2
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    • pp.86-94
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    • 2023
  • Objective: To compare Octopus multipurpose (MP) electrodes, which are capable of saline instillation and direct tissue temperature measurement, and conventional electrodes for radiofrequency ablation (RFA) in porcine livers in vivo. Materials and Methods: Sixteen pigs were used in this study. In the first experiment, RFA was performed in the liver for 6 minutes using Octopus MP electrodes (n = 15 ablation zones) and conventional electrodes (n = 12 ablation zones) to investigate the effect of saline instillation. The ablation energy, electrical impedance, and ablation volume of the two electrodes were compared. In the second experiment, RFA was performed near the gallbladder (GB) and colon using Octopus MP electrodes (n = 12 ablation zones for each) with direct tissue temperature monitoring and conventional electrodes (n = 11 ablation zones for each). RFA was discontinued when the temperature increased to > 60℃ in the Octopus MP electrode group, whereas RFA was performed for a total of 6 minutes in the conventional electrode group. Thermal injury was assessed and compared between the two groups by pathological examination. Results: In the first experiment, the ablation volume and total energy delivered in the Octopus MP electrode group were significantly larger than those in the conventional electrode group (15.7 ± 4.26 cm3 vs. 12.5 ± 2.14 cm3, p = 0.027; 5.48 ± 0.49 Kcal vs. 5.04 ± 0.49 Kcal, p = 0.029). In the second experiment, thermal injury to the GB and colon was less frequently noted in the Octopus MP electrode group than that in the conventional electrode group (16.7% [2/12] vs. 90.9% [10/11] for GB and 8.3% [1/12] vs. 90.9% [10/11] for colon, p < 0.001 for all). The total energy delivered around the GB (2.65 ± 1.07 Kcal vs. 5.04 ± 0.66 Kcal) and colon (2.58 ± 0.57 Kcal vs. 5.17 ± 0.90 Kcal) were significantly lower in the Octopus MP electrode group than that in the conventional electrode group (p < 0.001 for all). Conclusion: RFA using the Octopus MP electrodes induced a larger ablation volume and resulted in less thermal injury to the adjacent organs compared with conventional electrodes.

Clinical and Electrophysiological Characteristics of Meralgia Paresthetica (대퇴감각이상증의 임상 및 전기생리학적 특징)

  • Choi, Mun Hee;Park, Hanul;Eom, Young In;Joo, In Soo
    • Annals of Clinical Neurophysiology
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    • v.15 no.2
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    • pp.48-52
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    • 2013
  • Background: Meralgia paresthetica (MP) is a mononeuropathy affecting the lateral femoral cutaneous nerve. The disease is often diagnosed clinically, but electrophysiological tests play an important role. The aim of this study is to clarify clinical characteristics of MP as well as the role of sensory nerve conduction study (NCS) in the diagnosis of MP. Methods: Sixty-five consecutive patients with clinical diagnosis of MP between March 2001 and June 2012 were retrospectively reviewed at a single tertiary center. General demographics, clinical characteristics and sensory NCS findings were investigated. Measurements of sensory NCS included the baseline-to-peak amplitude, side-to-side amplitude ratio and the conduction velocity. To compare between the normal and abnormal NCS groups, independent t-tests and chisquare test were performed. Results: Sixty-five patients had male predominance (56.9%) with mean age of $48.4{\pm}13.4$ years (range: 16-75). Seven patients (13.5%) had undergone operation or procedure before the symptom onset. The sensory nerve action potentials were obtainable in 52 (80%) of 65 clinically diagnosed MP patients. Sensory NCS revealed abnormalities in 38 patients (73.1%), and others (n=14, 26.9%) showed normal findings. Between the normal and abnormal NCS groups, there is no statistically significant difference on demographics or clinical features. Conclusions: We clarify the clinical features and sensory NCS findings of MP patients. Due to several limitations of sensory NCS, the diagnosis of MP could be accomplished both clinically and electrophysiologically.

Effects of a Commercial Extruded Pellet on Growth Performance and Water Quality in Growing Olive Flounder Paralichthys olivaceus (육성기 넙치 배합사료의 성장 및 수질 평가)

  • Kim, Kang-Woong;Kim, Kyoung-Duck;An, Cheul-Min;Son, Maeng-Hyun;Lee, Bong-Joo;Han, Hyon-Sob
    • Journal of Fisheries and Marine Sciences Education
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    • v.24 no.4
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    • pp.602-608
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    • 2012
  • This study was conducted to evaluate the effect of commercial extruded pellet (EP) diet on the growth and water quality compared with a raw fish moist pellet (MP) diet for flounder on field feeding experiments. Three replicate groups of 130 fish per each tank (initial weight of 380 g) were fed one of the EP and Moist pellet (MP) for 7 months. In field feeding experiment, no significant difference was observed in final mean weight of fish fed the experimental EP (1,233 g) and MP (1,237 g), and any noticeable problem caused by feeding the experimental EP was not found during the whole period of feeding trial. Feed efficiency of fish fed the experimental EP was higher than that of MP, and there was no significant difference in survival between the fish fed experimental EP and MP. The concentrations of SS, COD, TN and TP of seawater in tanks of MP groups were 1-5 times higher than those of EP groups. Therefore, these results strongly suggest that diet EP could be developed to replace MP diet for the marketable size of production for flounder without adverse effects on growth performance and water quality.

THE STABILITY OF THE EQUATION f(x+p) = kf(x)

  • Lee, Sang-Han;Jun, Kil-Woung
    • Bulletin of the Korean Mathematical Society
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    • v.35 no.4
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    • pp.653-658
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    • 1998
  • In this paper, we investigate the Hyers-Ulam stability of the (p,k)-MP functional equation.

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