• 제목/요약/키워드: motor activity

검색결과 533건 처리시간 0.034초

N-3계 지방산 적절 함량 식이의 docosahexaenoic acid 첨가가 기억력 관련 뇌 기능에 미치는 영향 (Effect of Treatment with Docosahexaenoic Acid into N-3 Fatty Acid Adequate Diet on Learning Related Brain Function in Rat)

  • 임선영
    • 생명과학회지
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    • 제19권7호
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    • pp.917-922
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    • 2009
  • SD계 흰쥐를 사용하여 motor activity 실험에서 동물들의 자발적인 운동성을 측정한 결과, 주어진 시간 내 움직인 시간과 움직인 거리에는 n-3 지방산이 적절히 함유된 식이군 (Adq group)과 DHA가 첨가된 식이군(Adq+DHA group)간에 유의적 차이를 관찰할 수가 없었다. 학습효과 실험에서 n-3 지방산이 적절히 함유된 식이군 (Adq group)의 경우 목적 플랫트폼까지 걸리는 시간이 DHA 첨가 식이군(Adq+DHA group)에 비하여 다소 길었으나 유의적 차이는 관찰할 수가 없었다. 수영 속도(swimming speed)에서 DHA 첨가 식이군(Adq+DHA group)의 경우, n-3 지방산이 적절히 함유된 식이군 (Adq group)에 비해 유의적으로 빨랐으나 수영 풀에서 움직인 거리 (swimming distance)에는 두 식이군 간의 유의적 차이가 없었다. 두 식이군의 흰쥐들이 수영한 시간(swimming time)과 쉬고 있는 시간(resting time)의 경우, 쉬는 시간에는 유의적 차이가 없었으나 수영 시간 또한 n-3 지방산이 적절이 함유된 식이(Adq group)로 사육된 쥐가 DHA가 첨가된 식이로 사육된 쥐(Adq+DHA group)보다 수영한 시간이 길었으나 여기서도 유의적 차이는 없었다. 기억력 테스트에서 n-3 지방산이 적절히 함유된 식이군(Adq group) 및 DHA가 첨가된 식이군(Adq+DHA group) 모두는 목적 플랫트폼이 있었던 A 지역에 대한 기억이 우수하여 다른 지역들인 B, C, D를 지나가는 횟수보다 유의적으로 많았음을 관찰하였다(p<0.05). 이상의 결과로부터 임신에서부터 성인이 될 때까지 n-3 지방산이 적절히 함유된 식이로 사육된 쥐와 비교할 때 DHA가 첨가된 식이로 사육된 흰쥐가 Morris water maze를 이용한 공간기억력 실험에서 다소 우수한 기억 학습효과를 나타내었으나 유의적 차이는 없었음을 관찰 할 수가 있었다.

뇌성마비 아동의 진동 자극 훈련이 상지기능에 미치는 영향 (Effect of Vibration Stimulation Training on Upper Extremity Function in Children with Cerebral Palsy)

  • 강셋별;김만제;유두한
    • 대한감각통합치료학회지
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    • 제21권1호
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    • pp.23-33
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    • 2023
  • 목적 : 본 연구의 목적은 경직성 편마비 뇌성마비 후기 아동의 위팔두갈래근에 진동자극을 적용한 훈련이 상지의 기능을 향상시키는데 도움이 되는지를 알아보는 것이다. 연구방법 : 본 연구는 13세에서 15세 사이의 경직성 편마비를 가진 뇌성마비 아동 3명을 대상으로 하였다. 개별대상자 실험연구 방법 중 다중 기초선 개별실험연구를 이용한 AB 연구 설계를 사용하였으며, 중재기간 동안 진동자극은 마비측 손에 제공되었다. 상지의 기능을 측정하기 위하여 사용된 평가는 라파엘 스마트 보드는 매 회기 별 중재 후 평가를 실시하였고, 젭슨-테일러 손 기능 평가(Jebsen-Tayler hand function test)와 운동 활동 척도 검사(Motor Activity Log; MAL)를 실험 전, 후로 실시하였다. 결과 : 라파엘 스마트 보드로 매 회기 상지기능의 부드러움과 종합점수를 측정한 결과 대상자 3은 평균값의 변화에서 유의미한 결과가 없었고 대상자 1, 2는 평균값에서 유의한 변화가 있었다. 중재 전후로 평가한 젭슨-테일러 손 기능 평가 및 운동 활동 척도 검사에서는 대상자 모두 유의한 변화를 보였다. 결론 : 진동자극을 적용한 훈련이 마비측에 대한 경험이 적은 편마비를 가진 아동에게 상지 기능과 움직임을 증진시킬 수 있는 긍정적인 영향을 보였다.

Anxiolytic activity of standardized extract of Korean ginseng - a study on exploratory behavior

  • Mohan, M;Kasture, SB;Balaraman, R
    • Advances in Traditional Medicine
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    • 제5권4호
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    • pp.301-307
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    • 2005
  • The roots of the plant Korean ginseng have been extensively used in the traditional Chinese herbal medicine. We investigated the standardized extract of Korean ginseng on animal models of anxiety based on exploratory behavior. Korean ginseng extract (KGE) (3, 10 and 30 mg/kg) was administered intra-peritoneally. The anxiolytic activity was studied using elevated plus maze (EPM) paradigm, light/dark apparatus (LDA), open field apparatus (OFA) and the hole board apparatus (HBA). Diazepam (1mg/kg) was used as a standard anxiolytic drug. In EPM, KGE (10 mg/kg) significantly (P < 0.05) increased the time spent in open arms and the number of entries in open arms. In LDA, KGE (10 mg/kg) increased the number of transitions. In OFA, KGE (3 and 10 mg/kg) significantly increased (P < 0.05) the number of squares traversed. In HBA the number of head pokes were significantly increased with KGE (3 and 10 mg/kg). KGE at all selected doses did not affect the motor coordination. Thus, the study suggests that saponin containing standardized Korean ginseng extract possess anxiolytic activity.

DARS에 의한 CAPSS 배출자료의 불확도 평가 (Uncertainty Assessment for CAPSS Emission Inventory by DARS)

  • 김정;장영기
    • 한국대기환경학회지
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    • 제30권1호
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    • pp.26-36
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    • 2014
  • The uncertainty assessment is important to improve the reliability of emission inventory data. The DARS (Data Attribute Rating System) have recommended as the uncertainty assessment technic of emission inventory by U.S. EPA (Environmental Protection Agency) EIIP (Emission Inventory Improvement Program). The DARS score is based on the perceived quality of the emission factor and activity data. Scores are assigned to four attributes; measurement/method, source specificity, spatial congruity and temporal congruity. The resulting emission factor and activity rate scores are combined to arrive at an overall confidence rating for the inventory. So DARS is believed to be a useful tool and may provide more information about inventories than the usual qualitative grading procedures (e.g. A through E). In this study, the uncertainty assessment for 2009 CAPSS (Clean Air Policy Support System) emission inventory is conducted by DARS. According to the result of this uncertainty assessment, the uncertainty for fugitive dust emission data is higher than other sources, the uncertainty of emission factor for surface coating is the highest value, and the uncertainty of activity data for motor cycle is the highest value. Also it is analysed that the improvement of uncertainty for activity data is as much important as the improvement for emission factor to upgrade the reliability of CAPSS emission inventory.

Inhibition of LPA5 Activity Provides Long-Term Neuroprotection in Mice with Brain Ischemic Stroke

  • Sapkota, Arjun;Park, Sung Jean;Choi, Ji Woong
    • Biomolecules & Therapeutics
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    • 제28권6호
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    • pp.512-518
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    • 2020
  • Stroke is a leading cause of long-term disability in ischemic survivors who are suffering from motor, cognitive, and memory impairment. Previously, we have reported suppressing LPA5 activity with its specific antagonist can attenuate acute brain injuries after ischemic stroke. However, it is unclear whether suppressing LPA5 activity can also attenuate chronic brain injuries after ischemic stroke. Here, we explored whether effects of LPA5 antagonist, TCLPA5, could persist a longer time after brain ischemic stroke using a mouse model challenged with tMCAO. TCLPA5 was administered to mice every day for 3 days, starting from the time immediately after reperfusion. TCLPA5 administration improved neurological function up to 21 days after tMCAO challenge. It also reduced brain tissue loss and cell apoptosis in mice at 21 days after tMCAO challenge. Such long-term neuroprotection of TCLPA5 was associated with enhanced neurogenesis and angiogenesis in post-ischemic brain, along with upregulated expression levels of vascular endothelial growth factor. Collectively, results of the current study indicates that suppressing LPA5 activity can provide long-term neuroprotection to mice with brain ischemic stroke.

Promoting Mobility in Older People

  • Rantanen, Taina
    • Journal of Preventive Medicine and Public Health
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    • 제46권sup1호
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    • pp.50-54
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    • 2013
  • Out-of-home mobility is necessary for accessing commodities, making use of neighborhood facilities, and participation in meaningful social, cultural, and physical activities. Mobility also promotes healthy aging as it relates to the basic human need of physical movement. Mobility is typically assessed either with standardized performance-based tests or with self-reports of perceived difficulty in carrying out specific mobility tasks. Mobility declines with increasing age, and the most complex and demanding tasks are affected first. Sometimes people cope with declining functional capacity by making changes in their way or frequency of doing these tasks, thus avoiding facing manifest difficulties. From the physiological point of view, walking is an integrated result of the functioning of the musculoskeletal, cardio-respiratory, sensory and neural systems. Studies have shown that interventions aiming to increase muscle strength will also improve mobility. Physical activity counseling, an educational intervention aiming to increase physical activity, may also prevent mobility decline among older people. Sensory deficits, such as poor vision and hearing may increase the risk of mobility decline. Consequently, rehabilitation of sensory functions may prevent falls and decline in mobility. To promote mobility, it is not enough to target only individuals because environmental barriers to mobility may also accelerate mobility decline among older people. Communities need to promote the accessibility of physical environments while also trying to minimize negative or stereotypic attitudes toward the physical activity of older people.

부운동영역의 뇌지도화 (Somatotopic Mapping of the Supplementary Motor Area)

  • 한영민;정수현;이헌;진공용;이상용;정경호
    • Investigative Magnetic Resonance Imaging
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    • 제8권1호
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    • pp.9-16
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    • 2004
  • 목적 : 운동, 감각, 단어형성 , 듣고이해하기, 기억력과제를주면서 기능적자기공명영상를 이용하여 부운동영역의 기능적 지도화를 한다. 대상 및 방법 : 16명의 오른손잡이 정상지원자를 대상으로 1.5 T자기공명영상기기를 사용하여 전뇌를 BOLD EPI를 기능적자기공명영상을 얻었다. 왼손가락운동, 고온감각, 단어형성 , 듣고이해하기 그리고 기억자극을 주면서 5번의 자극기와 휴식기를 반복하여 영상을 얻었다. p = 0.0001의 역치를 사용하여 활성화된 뇌의 지도화를 시행하였고 역치 이상의 뇌활성화가 보이는 부위를 MNI 공간으로 표시하여 각각의 자극에 대한 해부학적 위치와 활성화를 분석하였다. 결과 : 16명의 정상지원자 중 부운동영역의 활성화는 운동자극시 16명 모두에서, 감각자극시 11명, 단어형성자극시 15명, 듣고이해하기자극시 5명, 그리고 기억자극시 15명에서 보였다. 부운동영역중 앞부분의 활성화는 단어형성자극과 기억자극시 보였으며, 뒤부분의 활성화는 운동과 감각자극시 측정되었다. 운동과 감각자극시 자극부위와 반대편의 부운동영역에서 활성화, 그리고 단어형성자극과 기억자극시 왼쪽반구의 활성화가 주로 측정되었다. 결론 : 부운동영역은 운동과 감각 그리고 단어형성기능과 기억기능에 연관이 있는 뇌부위이며, 부운동영역중에서도 각각의 기능에 해당하는 부위가 존재한다.

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경피적전기신경자극 적용 시 적용강도가 성인남성의 위등세모근의 근활성도와 근경도에 미치는 영향 (Effects of Applying Intensity on Muscle Activity and Muscle Hardness of Upper Trapezius Muscle in Adult Males applying Transcutaneous Electrical Nerve Stimulation)

  • 김충유;배원식;차영주
    • 대한통합의학회지
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    • 제10권1호
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    • pp.129-136
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    • 2022
  • Purpose : The purpose of this study was to investigate the effect of applying intensity on the muscle activity and muscle hardness of the upper trapezius muscle in adult males when TENS (transcutaneous electrical nerve stimulation) was applied. In addition, this study intends to prepare the scientific basic data of TENS for the purpose of relaxation based on the experimental results. Methods : Eighty-seven healthy adult males participated in the experiment, and they were randomly divided into an experimental group and a control group. All subjects in this study were healthy subjects without musculoskeletal or nervous system damage. All subjects were subjects who voluntarily consented to the purpose and method of the experiment. All subjects were provided with a load by typing for 20 minutes, and muscle activity and muscle hardness of the upper trapezius muscle were measured immediately. Afterwards, TENS was given to each groups for 15 minutes, and the experimental group received stimulation at the motor threshold level, and the control group received a placebo stimulation. After stimulation, muscle activity and muscle hardness of the upper trapezius muscle were measured in the same method. The measured data were compared between groups through an independent t-test and dependent t-test. The statistical significance level was set at .05. Results : The application of TENS statistically significantly decreased the muscle activity and muscle hardness of the trapezius muscle in the experimental group, and the results showed a significant difference from the control group. Conclusion : Application of TENS significantly decreased the muscle activity and muscle stiffness of the upper trapezius muscle. The application of TENS of applying intensity that induces muscle contraction may induce relaxation by reducing the muscle activity and muscle hardness of the trapezius muscle.

Comparison of the Scapular Muscles Activity Between Individuals With and Without Scapular Winging During Shoulder Flexion With Load

  • Jung, Jang-hun;Kang, Seung-tak;Jung, Sung-hoon;Kwon, Oh-yun
    • 한국전문물리치료학회지
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    • 제29권2호
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    • pp.165-170
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    • 2022
  • Background: The serratus anterior (SA) muscle prevents scapular winging (SW) by stabilizing the medial border of the scapula during arm movement. The upper trapezius (UT) and lower trapezius (LT) muscles may compensate for the weak SA muscle in individuals with SW during shoulder flexion. However, there is no study to examine whether compensation by UT and LT occurs in individuals with SW. Objects: This study compared the muscle activities of UT, LT, and SA as well as the SA/UT activity ratio between individuals with and without SW during shoulder flexion with load. Methods: This study recruited 27 participants with SW (n = 14) and without SW (n = 13). Electromyography data of the SA, UT, and LT muscles and SA/UT activity ratio were recorded and analyzed during shoulder flexion with 25% load of the maximal shoulder flexion force. Independent t-test was used to compare the UT, LT, and SA muscle activities and SA/UT ratio between the groups with and without SW; statistical significance was set at α of 0.05. Results: SA activity was significantly lesser in the group with SW than in the group without SW. However, there were no significant differences in the UT and LT activities and SA/UT activity ratio between the two groups. Conclusion: The SA activity was lesser in the group with SW than in the group without SW with 25% load of the maximal shoulder flexion force, but there was no compensatory muscle activity of the UT and LT observed. Therefore, further studies are warranted to clarify the compensatory strategy of scapular stabilization in individuals with SW during shoulder flexion under other heavy load conditions.

지체장애인의 운동참여제약 측정척도 개발 -요인구조 탐색과 준거관련타당도 검증- (Developing a Scale for Measuring the Constraints in Physical Activity of People with Physical Disabilities - Verification of Factor Structure and Related Criterion Validity -)

  • 서은철;백재근
    • 재활복지
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    • 제21권1호
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    • pp.253-277
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    • 2017
  • 이 연구는 지체장애인의 운동참여제약을 측정할 수 있는 운동참여제약 측정도구(Constraints in Physical Activity Scale for people with physical Disabilities: CPASD)를 개발하는 데에 목적이 있다. 이를 위해 이 연구에서는 Messick(1995)의 통합적 타당도, Benson(1998)의 강력한 구인타당도 프로그램 틀을 기반으로 한 다섯 가지 단계로 연구를 설계하였고, 지체장애인 264명을 대상으로 공통요인모형과 측정모형을 적용하여 CPASD의 타당도 증거를 체계적으로 제시하였다. 이 연구의 결과와 논의를 토대로 결론을 제시하면 다음과 같다. 첫째, CPASD는 구인타당도의 증거를 제시하였다. 요인구조의 해석가능성과 요인계수의 적합성을 통해 지도자 제약, 경제적 제약, 편견, 운동환경 제약으로 구성된 4요인, 17개 문항으로 개발되었다. 둘째, 개발된 CPASD의 요인구조(지도자제약, 경제적제약, 편견, 운동환경제약)는 통계적으로 구분됨과 동시에, 기존 운동참여제약 관련 이론을 안정적으로 반영하였다. 셋째, 개발된 CPASD는 준거관련타당도 증거를 제시하였다. 지도자제약, 편견은 긍정적 운동정서와 부적인 상관관계를, 지도자제약, 편견, 운동환경제약은 부정적 운동정서와 정적인 상관관계를 나타내었다. 따라서 후속 연구에서는 CPASD의 요인로 도출된 지도자제약, 경제적제약, 편견, 운동환경제약과 관련된 현재의 제도, 실태 등을 재평가할 필요성이 대두되고, 이를 위해 CPASD를 활용한 인과관계검증, IRT 이론을 적용한 현실 수준정도를 판단할 필요가 있다.