• Korean Journal of Optics and Photonics
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• v.32 no.2
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• pp.68-78
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• 2021

A subminiature catadioptric omnidirectional optical system (SCOOS) with 2 mirrors, 6 plastic aspherical lenses, and an illumination system of 6 light emitting diodes, to observe the 360° panoramic image of the inner intestine, is optically designed and evaluated for a capsule endoscope. The total length, overall length, half field of view (HFOV), and F-number of the SCOOS are 14.3 mm, 8.93 mm, 51°~120°, and 3.5, respectively. The optical system has a complementary metal-oxide-semiconductor sensor with 0.1 megapixels, and an illumination system of 6 light-emitting diodes (LEDs) with 0.25 lm to illuminate on the 360° side view of the intestine along the optical axis. As a result, the spatial frequency at the modulation transfer function (MTF) of 0.3, the depth of focus, and the cumulative probability of tolerance at the Nyquist frequency of 44 lp/mm and MTF of 0.3 of the optimized optical system are obtained as 130 lp/mm, -0.097 mm to +0.076 mm, and 90.5%, respectively. Additionally, the simulated illuminance of the LED illumination system at the inner surface of the intestine within HFOV, at a distance of 15.0 mm from the optical axis, is from a minimum of 315 lx to a maximum of 725 lx, which is a sufficient illumination and visibility.

• Korean Journal of Optics and Photonics
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• v.31 no.6
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• pp.281-289
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• 2020

This paper reports a slim mobile lens design using a hybrid refractive/diffractive optical element. Conventionally a wide field of view (FOV) camera-lens design adopts a retrofocus type having a negative (-) lens at the forefront, so that it improves in imaging performance over the wide FOV, but with the sacrifice of longer total track length (TTL). However, we chose a telephoto type as a baseline design layout having a positive (+) lens at the forefront, to achieving slimness, based on the specification analysis of 23 reported optical designs. Following preliminary optimization of a baseline design and aberration analysis based on Zernike-polynomial decomposition, we applied a hybrid refractive/diffractive element to effectively reduce the residual chromatic spherical aberration. The optimized optical design consists of 6 optical elements, including one hybrid element. It results in a very slim telephoto ratio of 1.7, having an f-number of 2.0, FOV of 90°, effective focal length of 2.23 mm, and TTL of 3.7 mm. Compared to a comparable conventional lens design with no hybrid elements, the hybrid design improved the value of the modulation transfer function (MTF) at a spatial frequency of 180 cycles/mm from 63% to 71-73% at zero field (0 F), and about 2-3% at 0.5, 0.7, and 0.9 fields. It was also found that a design with a hybrid lens with only two diffraction zones at the stop achieved the same performance improvement.

• Korean Journal of Optics and Photonics
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• v.32 no.6
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• pp.286-295
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• 2021

A modified catadioptric omnidirectional optical system (MCOOS) using an RGB/NIR CMOS sensor is optically designed for a capsule endoscope with the front field of view (FOV) in visible light (RGB) and side FOV in visible and near-infrared (NIR) light. The front image is captured by the front imaging lens system of the MCOOS, which consists of an additional three lenses arranged behind the secondary mirror of the catadioptric omnidirectional optical system (COOS) and the imaging lens system of the COOS. The side image is properly formed by the COOS. The Nyquist frequencies of the sensor in the RGB and NIR spectra are 90 lp/mm and 180 lp/mm, respectively. The overall length of 12 mm, F-number of 3.5, and two half-angles of front and side half FOV of 70° and 50°-120° of the MCOOS are determined by the design specifications. As a result, a spatial frequency of 154 lp/mm at a modulation transfer function (MTF) of 0.3, a depth of focus (DOF) of -0.051-+0.052 mm, and a cumulative probability of tolerance (CPT) of 99% are obtained from the COOS. Also, the spatial frequency at MTF of 170 lp/mm, DOF of -0.035-0.051 mm, and CPT of 99.9% are attained from the front-imaging lens system of the optimized MCOOS.

• The Korean Journal of Nuclear Medicine Technology
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• v.18 no.1
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• pp.82-88
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• 2014

Purpose: The purpose of study was to evaluate radiation dose for pediatric patients by changing tube voltage (kVp) and tube current (mA) at minimum conditions. By evaluating radiation dose, we want to provide dose reduction for pediatric patients and maintain good quality of SPECT/CT images. Materials and Methods: Discovery NM/CT 670 Scanne was used as SPECT/CT. Tube voltages are 80 and 100 kvP. Tube currents are 10, 15, 20, 25 mA. Using PMMA (Polymethyl methacrylate) Phantom, radiation dose which were calculated at center and peripheral dose and SNRD (Signal to Noise Ratio Dose) were evaluated. Using the CT performance phantom, spatial resolution was evaluated as the MTF (Modulation Transfer Function) graph. Jaszczak phantom was used for SPECT image evaluation by CNR (Contrast to Noise to Ratio). Results: Radiation dose using the PMMA phantom was higher peripheral dose than center dose about 7%. SNRD were 7.8, 8.2, 8.3, 8.8, 8.8, 9.9, 9.8, 9.6 for 80 kVp 10, 15, 20, 25 mA, 100 kVp 10, 15, 20, 25 mA. We can distinguish 35, 45, 70, 71, 52, 58, 90, 110 linepair for 80 kVp 10, 15, 20, 25 mA, 100 kVp 10, 15, 20, 25 mA at resolution with MTF. CNR of SPECT images using CT attenuation map were 57.8, 57.7, 57.1, 56.7, 56.6, 56.7, 56.7, 56.7% for 80 kVp 10, 15, 20, 25 mA, 100 kVp 10, 15, 20, 25 mA. Conclusion: In this study, radiation dose for pediatric patients showed decreased low dose condition. And SNRD value was similar in all condition. Resolution showed higher value at 100kVp than 80kVp. for CNR, there was no significant difference. we should take additional study to prove better quality and dose reduction.

• Journal of Korean Ophthalmic Optics Society
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• v.21 no.3
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• pp.281-288
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• 2016

Purpose: The present study was aimed to investigate the change of optical quality in fully cured eyes from central serous chorioretionopathy(CSC) and CSC under treatment, respectively. Methods: A total of 136 eyes(68 subjects) was divided into CMC under treatment and its asymptomatic contralateral eye, fully cured eyes after being diagnosed with CMC and its contralateral eye, and normal eyes. Objective scattering index, cut-off value in modulation transfer function, focusing rate, PSF(Point Spread Function) width at 50%, 10% and the contrast sensitivity were measured and analyzed. Results: CMC under treatment showed statistically significant decrease in all evaluations of optical quality compared with asymptomatic contralateral eyes, fully cured eyes and normal eyes. Although there was no significant difference in optical quality between asymptomatic contralateral eyes of CMC under treatment and fully cured eyes, there was tendence in optical quality decreasing compared with normal eyes. Conclusions: From the study, it was revealed that the optical quality was different according to the treatment phase in CMC. The use of optical quality assessment for the decision of complete cure and the evaluation of prognosis in CMC is also proposed.

• Nuclear Engineering and Technology
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• v.53 no.6
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• pp.1942-1946
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• 2021

Gadolinium oxysulfide (GOS) is regarded as a novel scintillator for the realization of ultra-high spatial resolution in neutron imaging. Monte Carlo simulations of GOS scintillator show that the capability of its spatial resolution is towards the micron level. Through the time-of-flight method, the light output of a GOS scintillator was measured to be 217 photons per captured neutron, ~100 times lower than that of a ZnS/LiF:Ag scintillator. A detector prototype has been developed to evaluate the imaging solution with the GOS scintillator by neutron beam tests. The measured spatial resolution is ~36 ㎛ (28 line pairs/mm) at the modulation transfer function (MTF) of 10%, mainly limited by the low experimental collimation ratio of the beamline. The weak light output of the GOS scintillator requires an enormous increase in the neutron flux to reduce the exposure time for practical applications.

• Korean Journal of Radiology
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• v.24 no.10
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• pp.1006-1016
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• 2023

Objective: Computed tomography (CT) is an established method for the diagnosis, staging, and treatment of multiple myeloma. Here, we investigated the potential of photon-counting detector computed tomography (PCD-CT) in terms of image quality, diagnostic confidence, and radiation dose compared with energy-integrating detector CT (EID-CT). Materials and Methods: In this prospective study, patients with known multiple myeloma underwent clinically indicated whole-body PCD-CT. The image quality of PCD-CT was assessed qualitatively by three independent radiologists for overall image quality, edge sharpness, image noise, lesion conspicuity, and diagnostic confidence using a 5-point Likert scale (5 = excellent), and quantitatively for signal homogeneity using the coefficient of variation (CV) of Hounsfield Units (HU) values and modulation transfer function (MTF) via the full width at half maximum (FWHM) in the frequency space. The results were compared with those of the current clinical standard EID-CT protocols as controls. Additionally, the radiation dose (CTDIvol) was determined. Results: We enrolled 35 patients with multiple myeloma (mean age 69.8 ± 9.1 years; 18 [51%] males). Qualitative image analysis revealed superior scores (median [interquartile range]) for PCD-CT regarding overall image quality (4.0 [4.0-5.0] vs. 4.0 [3.0-4.0]), edge sharpness (4.0 [4.0-5.0] vs. 4.0 [3.0-4.0]), image noise (4.0 [4.0-4.0] vs. 3.0 [3.0-4.0]), lesion conspicuity (4.0 [4.0-5.0] vs. 4.0 [3.0-4.0]), and diagnostic confidence (4.0 [4.0-5.0] vs. 4.0 [3.0-4.0]) compared with EID-CT (P ≤ 0.004). In quantitative image analyses, PCD-CT compared with EID-CT revealed a substantially lower FWHM (2.89 vs. 25.68 cy/pixel) and a significantly more homogeneous signal (mean CV ± standard deviation [SD], 0.99 ± 0.65 vs. 1.66 ± 0.5; P < 0.001) at a significantly lower radiation dose (mean CTDIvol ± SD, 3.33 ± 0.82 vs. 7.19 ± 3.57 mGy; P < 0.001). Conclusion: Whole-body PCD-CT provides significantly higher subjective and objective image quality at significantly reduced radiation doses than the current clinical standard EID-CT protocols, along with readily available multi-spectral data, facilitating the potential for further advanced post-processing.