DOI QR코드

DOI QR Code

The Analysis of Optical Quality in Central Serous Chorioretinopathy by OQAS

OQAS를 이용한 중심장액성맥락망막병증의 광학적 질 분석

  • Choi, Jong Kil (Dept. of Optometry, Seoul National University of Science and Technology) ;
  • Lee, Kyung Min (HanGil Eye Hospital) ;
  • Kim, Heesung (Dept. of Optometry, Seoul National University of Science and Technology) ;
  • Kim, So Ra (Dept. of Optometry, Seoul National University of Science and Technology) ;
  • Park, Mijung (Dept. of Optometry, Seoul National University of Science and Technology)
  • 최종길 (서울과학기술대학교 안경광학과) ;
  • 이경민 (한길안과병원) ;
  • 김희성 (서울과학기술대학교 안경광학과) ;
  • 김소라 (서울과학기술대학교 안경광학과) ;
  • 박미정 (서울과학기술대학교 안경광학과)
  • Received : 2016.08.07
  • Accepted : 2016.09.19
  • Published : 2016.09.30

Abstract

Purpose: The present study was aimed to investigate the change of optical quality in fully cured eyes from central serous chorioretionopathy(CSC) and CSC under treatment, respectively. Methods: A total of 136 eyes(68 subjects) was divided into CMC under treatment and its asymptomatic contralateral eye, fully cured eyes after being diagnosed with CMC and its contralateral eye, and normal eyes. Objective scattering index, cut-off value in modulation transfer function, focusing rate, PSF(Point Spread Function) width at 50%, 10% and the contrast sensitivity were measured and analyzed. Results: CMC under treatment showed statistically significant decrease in all evaluations of optical quality compared with asymptomatic contralateral eyes, fully cured eyes and normal eyes. Although there was no significant difference in optical quality between asymptomatic contralateral eyes of CMC under treatment and fully cured eyes, there was tendence in optical quality decreasing compared with normal eyes. Conclusions: From the study, it was revealed that the optical quality was different according to the treatment phase in CMC. The use of optical quality assessment for the decision of complete cure and the evaluation of prognosis in CMC is also proposed.

목적: 중심장액성맥락망막병증을 치료 중인 눈과 완치된 눈의 광학적 질의 변화를 알아보았다. 방법: 총 68명 136안을 대상으로 중심장액성맥락망막병증을 치료 중인 눈 및 무증상 반대편 눈, 중심장액성맥락망막병증을 진단받은 후 완치된 눈 및 반대편 눈과 정상인 눈의 객관적 산란지수, 변조전달함수 값, 상의 집속률, 점상강도 분포함수 50%폭과 10% 폭 및 대비감도를 측정하여 분석하였다. 결과: 중심장액성맥락망막병증을 치료 중인 눈은 반대편 무증상 눈, 질환이 완치된 눈 및 정상 눈과 비교하여 모든 광학적 질 평가에서 통계적으로 유의하게 광학적 질의 저하가 나타났다. 중심장액성맥락망막병증을 치료 중인 반대편 무증상 눈과 완치된 눈의 경우는 통계적으로 유의하지는 않았지만 정상안보다 광학적 질의 저하 경향이 나타났다. 결론: 본 연구를 통하여 중심장액성맥락망막병증 치료 단계에 따라 광학적인 질에 차이가 있음을 밝혔으며, 중심장액성맥락망막병증의 완치 판정 및 예후 평가에서 광학적 질의 평가의 활용을 제안한다.

Keywords

References

  1. Rodriguez P, Navarro R, Gonzalez L, Hernandez JL. Accuracy and reproducibility of Zywave, Tracey and experimental aberrometers. J Refract Surg. 2004;20(6):810-817.
  2. Artal P, Benito A, Perez GM, Alcon E, De Casas A, Pujol J et al. An objective scatter index based on double-pass retinal images of a point source to classify cataracts. PLoS One. 2011;6(2):e16823. https://doi.org/10.1371/journal.pone.0016823
  3. Choi SH, Shin YI. Changes in higher order aberration according to tear-film instability analyzed by continuous measurement using wavefront. J Korean Ophthalmol Soc. 2012;53(8):1076-1080. https://doi.org/10.3341/jkos.2012.53.8.1076
  4. Vilaseca M, Arjona M, Pujol J, Issolio L, Guell JL. Optical quality of foldable monofocal intraocular lenses before and after injection: comparative evaluation using a double-pass system. J Cataract Refract Surg. 2009;35(8):1415-1423. https://doi.org/10.1016/j.jcrs.2009.03.022
  5. Benito A, Perez GM, Mirabet S, Vilaseca M, Pujol J, Marin JM et al. Objective optical assessment of tear-film quality dynamics in normal and mildly symptomatic dry eyes. J Cataract Refract Surg. 2011;37(8):1481-1487. https://doi.org/10.1016/j.jcrs.2011.03.036
  6. Diaz-Douton F, Benito A, Pujol J, Arjona M, Guell JL, Artal P. Comparison of the retinal image quality with a hartmann-shack wavefront sensor and a double-pass instrument. Invest Ophthalmol Vis Sci. 2006;47(4):1710-1716. https://doi.org/10.1167/iovs.05-1049
  7. Koh S, Maeda N, Kuroda T, Hori Y, Watanabe H, Fujikado T et al. Effect of tear film break-up on higher-order aberrations measured with wavefront sensor. Am J Ophthalmol. 2002;134(1):115-117. https://doi.org/10.1016/S0002-9394(02)01430-7
  8. Schiffman RM, Christianson MD, Jacobsen G, Hirsch JD, Reis BL. Reliability and validity of the ocular Surface Disease Index. Arch Ophthalmol. 2000;118(5):615-621. https://doi.org/10.1001/archopht.118.5.615
  9. Norrby NE, Grossman LW, Geraghty EP, Kreiner CF, Mihori M, Patel AS et al. Determining the imaging quality of intraocular lenses. J Cataract Refract Surg. 1998;24(5):703-714. https://doi.org/10.1016/S0886-3350(98)80270-8
  10. Kwak AY, Choi MJ, Seo KY, Ahn JM. Comparison of optical quality between two intraocular lense using double-pass based optical quality analysis system. J Korean Ophthalmol Soc. 2013;54(12):1818-1823. https://doi.org/10.3341/jkos.2013.54.12.1818
  11. von Graefe A. Ueber centrale recidivirende retinitis. Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1866;12:211-215.
  12. Gass JDM. Pathogenesis of disciform detachment of the neuroepithelium II. Idiopathic central serous choroidopathy. Am J Ophthalmol. 1967;63(3):587-615.
  13. Bennett G. Central serous retinopathy. Br J Ophthalmol. 1995;39(10):605-618.
  14. Konno S, Akiba J, Yoshida A. Retinal thickness measurements with optical coherence tomography and the scanning retinal thickness analyzer. Retina. 2001;21(1):57-61. https://doi.org/10.1097/00006982-200102000-00010
  15. Cohen AI. A possible cytological basis for the 'R'membrane in the vertebrate eye. Nature. 1965;205(4977):1222-1223. https://doi.org/10.1038/2051222a0
  16. Boulton M, McKechnie NM, Breda J, Bayly M, Marshall J. The formation of autofluorescent grannules in cultured human RPE. Invest Ophthalmol Vis Sci. 1989;30(1):82-89.
  17. Kim SH, Choi KS, Lee SJ. Macular thickness changes with age and gender in emmetropia using spectral domain optical coherence tomography. J Korean Ophthalmol Soc. 2011;52(3):299-307. https://doi.org/10.3341/jkos.2011.52.3.299
  18. Lee YJ. Analysis of factors associated with variability in measures obtained by spectral domain optical coherence tomography. J Korean Ophthalmol Soc. 2012;53(5):639-646. https://doi.org/10.3341/jkos.2012.53.5.639
  19. Wagner-Schuman M, Dubis AM, Nordgren RN, Lei Y, Odell D, Chiao H. Race- and sex-related differences in retinal thickness and foveal pit morphology. Invest Ophthalmol Vis Sci. 2011;52(1):625-634. https://doi.org/10.1167/iovs.10-5886
  20. Ko BW, Shin YW, Lee JM, Song YM, Lee BR. Comparison of macular thickness measurements between fourier-domain and time-domain optical coherence tomography in normal eyes and eyes with macular diseases. J Korean Ophthalmol Soc. 2009;50(11):1661-1668. https://doi.org/10.3341/jkos.2009.50.11.1661
  21. Kim SH, Park JY, Park TK, Ohn YH. Use of spectral-domain optical coherence tomography to analyze macular thickness according to refractive error. J Korean Ophthalmol Soc. 2011;52(11):1286-1295. https://doi.org/10.3341/jkos.2011.52.11.1286
  22. Chung CK, Chin HS, Moon YS. Comparision of results of electroretinogran, fluorescein angiogram and color vision tests in acute central serous chorioretinopathy. J Korean Ophthalmol Soc. 2005;46(1):71-77.
  23. Ahn YS, Park TK, Ohn YH, Gwak HW. Mulitifocal electroretinogram abnormalities of central serous chorioretinopathy. J Korean Ophthalmol Soc. 2003;44(10):2265-2277.
  24. Jung HG, Lim TH. The recovery of optical quality after laser vision correction. J Korean Ophthalmol Soc. 2013;27(4):249-255. https://doi.org/10.3341/kjo.2013.27.4.249
  25. Kwon KN, Park SH, Kim SR, Park M. The changes in contrast sensitivity and glare sensitivity when wearing circle contact lenses after the refractive surgery. J Korean Ophthalmic Opt Soc. 2016;21(1):23-34. https://doi.org/10.14479/jkoos.2016.21.1.23
  26. Lee K, Sohn J, Choi JG, Chung SK. Optical quality in central serous chorioretinopathy. Invest Ophthalmol Vis Sci. 2014;55(12):8598-8603. https://doi.org/10.1167/iovs.14-14679
  27. Choi JK, Lee KM, Kim S, Kim SR, Park M. Analysis visual acuity and retinal state in the eyes with central serous chorioretinopathy. J Korean Ophthalmic Opt Soc. 2016;21(2):137-146. https://doi.org/10.14479/jkoos.2016.21.2.137