• Applied Biological Chemistry
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• 제41권8호
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• pp.568-571
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• 1998

The conformations of human insulin precursors, proinsulin and preproinsulin, are described in terms of molecular dynamics simulations. Despite the presence of the C-peptide and/or the signal peptide, molecular dynamics calculations utilizing the hydration shell model over a period of 500 ps indicate that the native conformations of the A and B chains are well conserved in both cases. These results further support the NMR spectroscopy results that the C-peptide is relatively disordered and does not influence the overall conformation of the native structure. The robustness of the native structure as demonstrated by experiment and simulation will permit future protein engineering applications, whereby the expression or purification yields can be improved upon sequence modification of the C-peptide and/or the signal peptide.

• 한국소음진동공학회논문집
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• 제26권7호
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• pp.865-874
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• 2016

This research is concerned with the experimental investigation on the vibrations of a flexible two-link system for verifying the theoretical result from simplified equations of motion for the system along with the kinematical synthesis are proposed to simulate the elastic vibrations of a previous study. The structure consists of flexible two-links; The link 2 is attached to the end of the link 1. The link 1 is made of composite fiber reinforced polymer and the link 2 is an aluminum beam. In order to verify the theoretical result, a flexible two-link system operated by the AC and RC servo motors was constructed. Experimental results show that the dynamic modeling approach and the kinematical synthesis proposed in this paper are effective.

• 한국CDE학회논문집
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• 제7권2호
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• pp.96-101
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• 2002

Rapid Prototyping (RP) technology has been advanced to fabricate initial prototypes from various materials. Stratasys′ Fused Deposition Modeling (FDM) is one of the typical RP processes that provide functional prototypes of ABS plastic. In order to predict the behavior of final ABS parts, it is critical to understand the material properties of the raw FDM process material, and the effect that FDM build parameters have on the FDM part. In this paper, we seek to characterize the properties of ABS parts fabricated by the FDM 1650. Using the Design of Experiment (DOE) approach, the process parameters of FDM, such as raster orientation, air gap, bead width, color, and model temperature were examined. Tensile strengths of crisscross specimens, 〔45°/-45°〕, cross specimens, 〔0°/90°〕, and directionally fabricated tensile specimens (〔0°〕 and 〔90°〕) were measured and compared with the injection molded FDM-ABS P400 material. For the FDM parts made with a -0.003"air gap, the typical tensile strength ranged between 50 percent and 83 percent of the strength of injection molded ABS P400. From the experiments, a couple of build rules for designing FDM parts were obtained.

• 한국농공학회논문집
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• 제57권1호
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• pp.89-97
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• 2015

This study is to assess the effect of non-point source pollution discharge loads between tillage and no-tillage applications for upland crop areas using SWAT (Soil and Water Assessment Tool) watershed modeling. For Byulmi-cheon small rural catchment ($1.17km^2$) located in upstream of Gyeongan-cheon watershed, the rainfall, discharge and stream water quality have been monitored in the catchment outlet since 2011. The SWAT model was calibrated and validated in hourly basis using 19 rainfall events during 2011-2013. The average Nash-Sutcliffe model efficiency and $R^2$ (determination coefficient) for streamflow were 0.67 and 0.79 respectively. Using the 10 % surface runoff reduction from experiment results for no-tillage condition in field plots of 3 % and 8 % slopes under sesami cultivation, the soil saturated hydraulic conductivity for upland crop areas was adjusted from 0.001 mm/hr to 0.0025 mm/hr in average. Under the condition, the catchment sediment, T-N (total nitrogen, TN), and T-P (total phosphorus, TP) discharge loads were reduced by 6.9 %, 7.4 %, and 7.7 % respectively.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2003년도 ICCAS
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• pp.1146-1151
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• 2003

Pneumatic servo valve is an electro-mechanical device which change electric signals to a proper pneumatic signals, that is, flowrate and pressure. In this study, a pneumatic servo valve was designed and each simulation was conducted on any variation in the flowrate depending upon the magnetic force of the linear force motor and the displacement of the spool. And permanent magnet was used as a material for the plunger of the servo valve. Thereby, a low electrical power consumption type coil was desinged. And a modeling for the coil design was conducted by using the magnetic circuit. also, the feasibility of the modeling was verified by using a commercial magnetic field analysis program. The designed and fabrication of the spool and sleeve, position sensor, servo controller and the dynamic characteristic verified by the experiment.

• 한국연소학회지
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• 제9권2호
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• pp.30-37
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• 2004

Coal combustion in an iron ore sintering bed is a key parameter that determines quality of the sintered ores and productivity of the process. In this study, effects of the different types of coal - coke and anthracite - on the combustion in the iron ore sintering bed are investigated by modeling and experiment. Fuel characteristics of coke and anthracite are observed through a set of basic analysis and thermo-gravimetric analysis. Coke has a higher reactivity than anthracite due to the difference of surface area and density, and these characteristics are reflected in the 1-D unsteady simulation of the iron ore sintering bed. Calculation results show that different reactivity of the fuel can affect the bed combustion.

• 대한기계학회논문집A
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• 제26권8호
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• pp.1638-1644
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• 2002

A novel locomotion using the pneumatic impulsive actuator was proposed for robotic colonoscope. This locomotion showed good moving performance in the environment of rigid pipe, however, the displacement per one impact(step displacement) is greatly reduced due to the low stiffness and high damping characteristics of the colon. Therefore, the modeling technique based on spring and damping system is studied to predict the step displacement and some parametric studies are carried out to investigate main parameters that influence the step displacement of locomotion. Based on simulation result, a new locomotion to control the resistance force is suggested and fabricated. Through the experiment on the colon, the usefulness of modeling technique is confirmed and successful improvement of moving characteristics is achieved.

• 설비공학논문집
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• 제12권7호
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• pp.649-658
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• 2000

Thermodynamic modeling of low-pressure scroll compressor was developed by combining continuity and energy conservation equation. Suction gas heating was considered using energy balance inside the low pressure shell. Pressure, temperature and mass of refrigerant-22 as a function of orbiting angle were calculated by solving the governing equations using fourth order Rung-Kutta scheme. Motor efficiency was taken by experiments with a variation of frequency. The developed model was applied to the analysis of an inverter driven scroll compressor with a variation of frequency, pressure ratio and operating conditions. The model was verified with the experimental results at the same operating conditions. The developed model was adequate to predict performance of the inverter driven scroll compressor as a function of operating conditions. Calculated parameters from the model were discharge temperature, mass flow rate, power input, COP, and thermodynamic properties with respect to orbiting angle. To enhance the performance of a scroll compressor, it is essential to diminish leakage at low frequency level and improve the mechanical efficiency at high frequency level.

• 한국생산제조학회지
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• 제24권3호
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• pp.334-341
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• 2015

This paper summarizes the results of an investigation into the environmental factors that have an indirect impact on parts quality, as well as those process variables and modeling information that have a direct impact. The effects of strength, surface hardness, roughness, and accuracy of shape, that is, qualities that users generally need to know, were evaluated with laminating direction experimentally. The 3D printing methods used in this experiment were fused deposition modeling (FDM), stereolithography apparatus (SLA), selective laser sintering (SLS), 3D printing (3DP) and laminated object manufacturing (LOM). The goal was to achieve a high standard of quality control and product quality by optimizing the fabrication process.

• 설비공학논문집
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• 제18권11호
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• pp.933-940
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• 2006

In this study multi-zone modeling program CONTAM 2.4 developed by NIST is used for estimating the air disinfection rate of the interior of a room which is set up the indoor air disinfection system with filter and ultra violet germicidal irradiation (UVGI). Developed models those enable to predict the transmission of air home contagion such as bacteria and fungus generated in our daily life are useful model for designning air cleaning & ventilation system of building. Also, results indicate that these models are enable to compute the real situation that is almost impossible of carrying out experiment in an actual condition due to biohazard problems and suggest that engineers will use these models as a design tool for the future immune building system.