• Asian-Australasian Journal of Animal Sciences
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• v.32 no.3
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• pp.334-340
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• 2019

Objective: The objective of this study was to investigate the genetic components of daily milk yield and to re-rank bulls in South Korea by estimated breeding value (EBV) under heat stress using the temperature-humidity index (THI). Methods: This study was conducted using 125,312 monthly test-day records, collected from January 2000 to February 2017 for 19,889 Holstein cows from 647 farms in South Korea. Milk production data were collected from two agencies, the Dairy Cattle Genetic Improvement Center and the Korea Animal Improvement Association, and meteorological data were obtained from 41 regional weather stations using the Automated Surface Observing System (ASOS) installed throughout South Korea. A random regression model using the THI was applied to estimate genetic parameters of heat tolerance based on the test-day records. The model included herd-year-season, calving age, and days-in-milk as fixed effects, as well as heat tolerance as an additive genetic effect, permanent environmental effect, and direct additive and permanent environmental effect. Results: Below the THI threshold (${\leq}72$; no heat stress), the variance in heat tolerance was zero. However, the heat tolerance variance began to increase as THI exceeded the threshold. The covariance between the genetic additive effect and the heat tolerance effect was -0.33. Heritability estimates of milk yield ranged from 0.111 to 0.176 (average: 0.128). Heritability decreased slightly as THI increased, and began to increase at a THI of 79. The predicted bull EBV ranking varied with THI. Conclusion: We conclude that genetic evaluation using the THI function could be useful for selecting bulls for heat tolerance in South Korea.

• Journal of The Korean Association of Information Education
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• v.24 no.6
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• pp.551-562
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• 2020

The purpose of this study is to investigate the effects of Data Science Education classes using PBL-based App Inventor on elementary student Computational Thinking and Creativity. Based on the results of the pre-requisite analysis by Rossett's demand analysis model, PBL-based Data Science Education class was designed according to the procedure of ADDIE model which is 42 hours of classroom instruction for elementary student. As a result of the Paired t-test, it was proved that the Computational Thinking was statistically significantly improved in the post-test. In addition, as a result of the Paired t-test and Wilcoxon's signed rank test, it was found that the sub-factors of Creativity were 'Originality', 'Fluency', 'Closure', 'Average', and 'Index'. Therefore, it was confirmed that the PBL-based Data Science Education class using App Inventor is effective in improving Computational Thinking and Creativity of elementary student.

• The Journal of the Acoustical Society of Korea
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• v.27 no.6
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• pp.296-302
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• 2008

This study investigated that the preference model of soloist performers for both vocal and instrumental types in terms of a stage support parameter, ST1. The test was carried out on a stage of a fan-shaped multi-purpose hall with orchestra shell. Objective measurements were carried out at 15 positions on the stage to evaluate various stage condition. The results showed that ST1 varies between -19.9 and -11.3 dB. Vocal and instrumental players participated in performance evaluation test as they played at 5 selected positions according to ST1 values. Players' preference was evaluated by 5-point rating and rank ordering method. As a result, it was found that the preference model of vocalist is different from that of instrumentalist. It was also found that the ST1 does not correlate well with the performer's preference.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.11 no.2
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• pp.198-208
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• 2000

Objectives：This study was conducted to evaluate the effects of the attachment promotion program which was designed to promote attachment between autistic children and their mothers. The program was consisted of play activity centered mother-child interaction, educational activity for mothers by lecture, video-feedback session, and emotional supports. Methods：The subjects were consisted of 11 pairs of mother and child(7 for participant group：PG, 4 for non-participant group：NPG), who were 2-4 years-old autistic children. The data were collected by video-taping, behavioral observations, and analyzed by Wilcoxon Rank(Sign) Sum Test and Content Analysis. Results：The total attachment score increased from pre test to post-test of PG was significantly higher than that of NPG. The scores of attachment behaviors indicating proximity, mutuality and affect increased significantly(p<.05), while some behaviors indicating synchrony and jointattention did not. Especially the affectionate behaviors of PG demonstrated the most notable changes and they became more active, voluntary and reciprocal. After the program, the mother's nurturing behaviors of PG increased more than that of NPG, with no significant difference between two groups. The mother's behaviors to her child of PG became more child-centered, positively responsive, supportively expressive. As the attachment was promoted, there were also positive changes in the children's autistic behaviors with a great deal of individual differences. Conclusion：Our findings suggest that Mother-Child Attachment Promotion Program could be an effective early intervention model for autistic children.

• Journal of Hospice and Palliative Care
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• v.18 no.1
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• pp.51-59
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• 2015

Purpose: Predicting life expectancy of terminally ill cancer patients is very important. In many studies, ferritin is detected at higher levels in the sera of cancer patients, and higher ferritin level correlates with aggressiveness of disease and poor outcomes of patients. This study evaluated a prognostic role of serum ferritin levels in terminally ill cancer patients. Methods: This study enrolled 65 terminally ill cancer patients from March through June 2012. We assessed routine laboratory findings including serum ferritin levels as well as demographic and clinical characteristics of the patients. To examine the association between serum ferritin levels and patient's characteristics, we used Spearman's correlation analysis, Wilcoxon's rank sum test or Kruskal-Wallis test, as appropriately. For multivariate analysis, Cox's proportional hazard regression model was used to evaluate significance of serum ferritin levels as a prognostic factor. Results: A negative correlation between serum ferritin levels and survival time was found. After adjusting for sex, age, performance status, creatinine levels and white blood cell counts, serum ferritin levels were significantly associated with survival time. Conclusion: Even at the very end of life of terminal cancer patients, serum ferritin levels were an independent prognostic factor for survival.

• Journal of fish pathology
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• v.14 no.1
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• pp.31-36
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• 2001

A novel clonidine binding sites were characterized in the intestinal membrane isolated from seawater eels, Anguilla japonica. The specific clonidine binding sites consisted of at least two classes, high affinity ($K_d=1.4{\pm}0.3$ nM n = 5) and low affinity ($K_d=175{\pm}34$ nM n = 5) sites. The specific binding of 2 nM [$^3H$]clonidine was most enhanced at $20^{\circ}C$ and pH 7.5, and reversed by unlabelled clonidine. Such binding was hardly inhibited by adrenaline, yohimbine or rauwolscine, indicating that most binding sites are distinct from $\alpha_2$-adrenoceptor. The specific clonidine binding sites was inhibited by various imidazoline/guanidinium drugs, indicating existence of imidazoline/guanidinium receptive sites (IGRS) or imidazoline receptors in the eel intestine. Competition experiments revealed that rank order to displace 2 nM [$^3H$]clonidine from their binding sites was as follows : guanabenz > cirazoline = naphazoline = UK14,304 = ST587 $\geq$ clonidine $\geq$ idazoxan = RX821002 = tolazoline > ST93 = oxymetazoline = amiloride = ST91 > yohimbine = efaroxan = rauwolscine $\geq$ adrenaline = ST567 = histamine = agmatine. Although physiological role of IGRS is not clear yet even in mammalian cell/tissues, eel intestine may be a good model to elucidate how the IGRS act in the cell and to decide what is the endogenous ligand for the IGRS.

• KIPS Transactions on Software and Data Engineering
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• v.4 no.1
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• pp.37-44
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• 2015

In traditional social network analysis, the betweenness centrality measure has been heavily used to identify the relative importance of nodes. Since the time complexity to calculate the betweenness centrality is very high, however, it is difficult to get it of each node in large-scale social network where there are so many nodes and edges. In our past study, we defined a new type of network, called the expanded ego network, which is built only with each node's local information, i.e., neighbor information of the node's neighbor nodes, and also defined a new measure, called the expanded ego betweenness centrality. In this paper, We propose algorithm that quickly computes expanded ego betweenness centrality by exploiting structural properties of expanded ego network. Through the experiment with virtual network used Barab$\acute{a}$si-Albert network model to represent the generic social network and facebook network to represent actual social network, We show that the node's importance rank based on the expanded ego betweenness centrality has high similarity with that the node's importance rank based on the existing betweenness centrality. We also show that the proposed algorithm computes the expanded ego betweenness centrality quickly than existing algorithm.

• The Journal of the Korea Contents Association
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• v.20 no.8
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• pp.101-113
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• 2020

This study aimed to explore how effective explicit form-focused instruction (FFI) is in teaching the schwa vowel /ə/ to EFL students in a classroom setting. The participants were 25 female high school students, who were divided into the experimental group (n=13) and the control group (n=12). One female American also participated in the study for a speech sample as a reference. The treatment, which involves shadowing model pronunciation by the researcher and a free text-to-speech software and the researcher's feedback in a private session, was given to the control group over a month and a half. The speech samples, for which the participants read the 14 polysyllabic stimulus words followed by the sentences containing the words, were collected before and after the treatment. The paired-samples t test and non-parametric Wilcoxon signed-rank test were used for analysis. The results showed that the participants of the experimental group in the post-test reduced the duration of the schwa by around 40 percent compared to the pre-test. However, little effect was found in approximating the participants' distribution patterns of /ə/ measured by the F1/F2 formant frequencies to the reference point, which was 539 Hz (F1) by 1797 Hz (F2). The findings of this study suggest that explicit FFI with multiple repetitions and corrective feedback is partly effective in teaching pronunciation.

• Korean Journal of Social Welfare
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• v.59 no.3
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• pp.201-227
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• 2007

This study is to investigate determinants of social workers' career commitment, compare the level of career commitment of social workeks by social work organization, and analyze the effects of career commitment on job attitudes. Social workers working for government agencies and community welfare centers and institutions in Busan city and Gyeongnam province were surveyed using structured questionnaires and 326 usable questionnaires were obtained. The questionnaires were analyzed for job, career, role, and organizational justice characteristics models and comprehensive model using SPSS/PC+.. The results are as follows; the level of social worker's career commitment was relatively high but the level of career commitment of social workers working for government agencies was slightly lower than that of social workers working for private agencies. According to the demographic characteristics, the level of career commitment of males was higher than that of famales. That of older workers was higher than that of younger worker, that of 2nd rank workers was higher than that of 1st rank workers. Task significance, task identity, feedback for the job done, career satisfaction, low role conflict, high distributive justice and interactive justice were related to higher level of career commitment while the skill variety was related to the lower level of career commitment. However, the main determinants differ according to the social work organization. Career commitment affected negatively on the career turnover intention while it affected positively on organizational commitment, organizational citizenship behavior, job involvement, and intrinsic job satisfaction. Therefore, different approaches and systematic measures are needed according to the organization.

• Journal of Chest Surgery
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• v.42 no.5
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• pp.610-614
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• 2009

Background: Several trials have reported on whether adjuvant chemotherapy for resected stage IB non-small cell lung cancer is needed. The aim of our study was to investigate prognostic factors for recurrence to help identify patients who should receive adjuvant chemotherapy. Material and Method: We reviewed the cases of 48 stage IB non-small cell lung cancer patients between 1997 and 2006. Disease-free survival and overall survival rates were calculated by the Kaplan-Meier method. Univariate analysis was performed with the log rank test and multivariate analysis was done using Cox's proportional hazard model. Result: The median follow-up time was 48 months. The overall survival rate was 55.9%, and the disease-free survival rate was 48.6%. Of 8 variables, two factors, visceral pleural invasion and Iymphovascular invasion, were prognostic factors of disease-free survival (univariate analysis). Visceral pleural invasion was a significant prognostic factor in multivariate analysis, and overall survival in com-pared one or more variable such as visceral pleural invasion or, and lymphovascular invasion with the other variables. Conclusion: Visceral pleural invasion was identified as a poor prognostic factor and it may help select which patients will benefit from adjuvant chemotherapy in addition to more comprehensive follow-up.