• The Korea Journal of Herbology
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• v.28 no.4
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• pp.93-100
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• 2013

Objectives : This study was to evaluate the anti-inflammatory and anti-pruritic effects of WSY-1075 composited with Corni Fructus, Angelica gigantis Radix, Lycii Fructus, Ginseng Radix, Cervi parvum Cornu and Cinnamomi Cortex in rat peritoneal mast cells (RPMCs) and scratching mouse model. Methods : WSY-1075 was prepared by extracting with 30% ethanol. In the present study, we investigated the effect of WSY-1075 on the production of tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), interleukin-$1{\beta}$ (IL-$1{\beta}$) and histamine in rat peritoneal mast cells (RPMCs) activated with phorbol 12-myristate 13-acetate (PMA) plus calcium ionophore A23187, and on the scratching behavior in mice treated with pruriogens. Results : WSY-1075 was not cytotoxic effect in used all concentration. PMA plus A23187 treatment significantly increased TNF-${\alpha}$, IL-$1{\beta}$ and IL-6 production compared with media control in RPMCs. However, TNF-${\alpha}$, $IL1{\beta}$ and IL-6 production increased by PMA plus A23187 treatment were significantly inhibited by WSY-1075 (200 ${\mu}g/mL$ and 400 ${\mu}g/mL$). WSY-1075 also inhibited the histamine release from RPMCs stimulated by compound 48/80, which promotes histamine release. Moreover, WSY-1075 administration had an inhibitory effects on the scratching behavior induced by pruritogen (compound 48/80, histamine, serotonin and substence P) in ICR mice. Conclusion : These results suggest that WSY-1075 administration (200 mg/kg or 400 mg/kg) has the anti-inflammatory and anti-pruritic effects on the activated rat peritoneal mast cell and mouse pruritus. WSY-1075 has a potential use as a composition of medicinal plants for treatment against inflammation- and pruritus-related disease.

• Journal of Aerospace System Engineering
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• v.16 no.4
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• pp.60-67
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• 2022

An Electro-Optical Tracking System (EOTS) is an electric optical system with EO/IR cameras, laser sensors, and an IMU. The EOTS calculates coordinates of targets, using attitude and acceleration measured by the IMU. In particular for an armed aircraft, the performance of the weapon system depends on how quickly and accurately it acquires the target coordinates. The IMU should be operated after alignment is complete, to meet the coordinate accuracy required by the weapon system so the initial stabilization time of the IMU should be reduced, by quickly measuring the attitude and acceleration. Alignment is the process of determining the initial attitude by resolving the attitude error of the IMU, and the IMU of mission equipment such as an airborne EOTS, uses velocity matching based on the velocity from GPS/INS for aircraft navigation. In this paper, a method is presented to improve the transfer alignment performance of the airborne EOTS, by maneuvering aircraft and the mission equipment. First, the performance factor of the alignment was identified, as a heading error through the velocity matching model and simulation results. Then acceleration maneuvers and attitude changes were necessary, to correct the error. As a result of flight tests applied to an EOTS on a OOO aircraft system, the transfer alignment performance was improved as the duration time was decreased, by more than five times when the aircraft accelerated by more than 0.2g and the EOTS was moving until 6.7deg/s.

• International Journal of Computer Science & Network Security
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• v.22 no.5
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• pp.79-88
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• 2022

Modern production requires production staff who have design competence, experience and skills to work in various types of work integrated into professional activities. Possession of digital design methods significantly expands the opportunities for professional activities of qualified workers. The purpose of our study was to study the impact of pedagogical conditions on the formation of design competence of future qualified workers in a group work. We have identified a set of pedagogical conditions that promote the development of professionally oriented artistic and technical creativity of workers in the conditions of curricular and extracurricular activities, which include motivational-target, procedural-semantic, organizational-technological, and subject-oriented. It is shown that the formation of design competence is determined by motivational, informational-active and reflection criteria, which are aimed at motivational-value, cognitive, operational-active, creative, social and emotional components of this competence. The methodology of the research is highlighted, which includes the use of the following methods: determination of the personality's motivational sphere in order to identify strong and weak motives of students activity; multiple intelligence to identify students talents in the direction of practical intelligence, which is important for design competence; determining the level of creative activity to identify manifestations of students creative abilities; identifying the type of students innovative thinking in order to develop motivation for success; factor-criterion model, developed on the basis of a qualimetric approach, which is used to identify the level of design competence formation in accordance with its components. The results of the study showed that the creation of separate pedagogical conditions in the institution of vocational education and training (VET) had a positive impact on the development of design competence, which shows the potential of artistic and technical design in the development of professional creativity of future qualified workers taking into account the environmental approach.

• Journal of Korean Neurosurgical Society
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• v.65 no.2
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• pp.204-214
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• 2022

Objective : Osteoporosis result from age-related decline in the number of osteoblast progenitors in the bone marrow. Probiotics have beneficial effects on the host, when administered in appropriate amounts. This study investigated the effects of probiotics expressing specific genes, especially the effects of genetically modified bone morphogenetic protein (BMP)-2-expressing Lactobacillus plantarum CJNU 3003 (LP) on ovariectomized rats. Methods : Twenty-eight female Wistar rats (250-300 g, 12 weeks old) were divided into four groups : the sham (control), the ovariectomy (OVX)-induced osteoporosis group (OVX), the OVX and LP (OVX/LP), OVX and genetically modified BMP-2-expressing LP (OVX/LP with BMP) groups. The three groups underwent bilateral OVX and two of these groups were administered two different types of LP via oral gavage daily. At 16 weeks post-OVX, blood was collected from the heart and the bilateral tibiae were extracted and were scanned by ex-vivo micro-computed tomography and stained with hematoxylin-and-eosin (H&E) and Masson's trichrome stain for pathological assessment. The serum levels of osteocalcin (OC), rat C-telopeptide of type I collagen (CTX-I), BMP-2, and receptor activator of nuclear factor-ĸB ligand (RANKL) were measured. Results : The 3D-micro-computed tomography images showed that the trabecular structure in the OVX/LP with BMP group was maintained compared with OVX and OVX/LP groups. No significant differences were detected in trabecular thickness (Tb.Th) between control and OVX/LP with BMP groups (p>0.05). Furthermore, a tendency toward increased BMD, trabecular bone volume, Tb.Th, and trabecular number and decreased trabecular separation was found in rats in the OVX/LP with BMP groups when compared with the OVX and OVX/LP groups (p>0.05). The H&E and Masson's trichrome stained sections showed a thicker trabecular bone in the OVX/LP with BMP group compared with the OVX and OVX/LP groups. There was no difference in serum levels of OC, CTX and RANKL control and OVX/LP with BMP groups (p>0.05). In contrast, significant differences were found in OC and CTX-1 levels between the OVX and OVX/LP with BMP groups (p<0.05). Conclusion : Our results showed that the expression of genetically modified BMP-2 showed inhibition effect for bone loss in a rat model of osteoporosis.

• Journal of the Korean Society for Library and Information Science
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• v.56 no.1
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• pp.5-25
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• 2022

In most countries, public libraries are knowledge information centers, complex cultural spaces, lifelong learning facilities, and third places for local residents. The social homage spoken on the premise of this identity and socio-cultural role is the knowledge and information agora, cultural infrastructure, living room in the city, and the university of the people. However, if there is a significant gap between public libraries regardless of country or region, it will inevitably lead to information gaps, regional gaps, and cultural inequality and cultural welfare gaps among local residents. This study is regarded as the essence of regional cultural facilities and premised that the regional gap in public libraries is a factor of regional cultural gaps. Based on this premise, the gap between the location quotient, input indicators, and output indicators of public libraries of regional governments in Korea and basic local governments in the Gyeongbuk region was analyzed. And this study derived core elements through correlation and regression analysis of input and output indicators of all public libraries nationwide, developed a management model for each indicator, and suggested a plan to resolve the relative gap for public libraries by city and county in Gyeongbuk.

• Journal of Korea Entertainment Industry Association
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• v.15 no.6
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• pp.153-163
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• 2021

This study has a main purpose that closely examines the structural relationship among A Study on the Structural Relationship of Achievement Goal Propensity, Sports Confidence, and Perceived Performance Using the Mentoring System of High School Leaders. In order to achieve it, the sample from high school student participants were accumulated by using convenience sampling that chose taekwondo championship in national. The samples were 500 people. and we excluded unsuitable sheet like that were decided as untruthful one and an omission and unclear. So the final samples were 465 people. On the basis of that, The statistical techniques, spss 24.0 and amos 24.0 program have been used for the analysis as per research purpose. The statistical analysis used in the research for a data analysis includes frequency analysis, confirmatory factor analysis, reliability analysis, correlation analysis, and structure equation model analysis. The research has drawn the following conclusions, based on the above mentioned research method and its procedures: First, The mentoring influences the achievement goal orientation. Second, The mentoring influences the sport confidence. Third, The achievement goal orientation influences the perceived performance. Fourth, The sport confidence influences the perceived performance.

• Korean Association of Arts Management
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• no.60
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• pp.155-191
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• 2021

The purpose of this study is to analyze the effect of art and culture experience according to art and culture perception on art and culture consumption. Accordingly, the perception expressed through the experiences of consumers was defined as the delivery of art and culture marketing strategies, and the behavior of consumers enjoying art and culture was measured. The research data were analyzed through an online survey. As a result of the analysis, sense, relation had a significant effect on the hedonistic factor, and the act, sense, emotion and relation had significant effects on the other's consciousness, and the behavioral and emotional factors had a significant effect on the intentional factors. The implication from the experience of relationships with others was found to have a negative(-) effect on all factors, which means to be the result of consumers' anxiety in enjoying art due to the pandemic. It is necessary to develop an online business model for consumers who naturally avoid it, and to narrow the gap between online and offline art and culture. Second, it is thought that sponsorship from companies is necessary so that artists who provide art and culture can produce high-quality contents. In the future, if it was studied the relationship between not only consumers who enjoy art and culture, but also suppliers and artists who provide art and culture, it will be able to understand the culture in-depth.

• Atmosphere
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• v.31 no.5
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• pp.625-635
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• 2021

South Korea established the 2050 Carbon Neutral Plan in response to the climate crisis, and to achieve this policy, it is very important to monitor domestic carbon emissions and atmospheric carbon concentration. Both CO₂ and CO are emitted from fossil fuel combustion processes, but the relative ratios depend on the combustion efficiency and the strength of local emission regulations. In this study, the relationship between CO₂ and CO was analyzed using ground observation data for the period of 2018~2020 at Anmyeon-do site and the CO/CO₂ ratio according to regional origin during high CO₂ cases was investigated based on the footprint simulated from Stochastic Time-Inverted Lagrangian Transport (STILT) model. CO₂ and CO showed a positive correlation with correlation coefficient of 0.66 (p < 0.01), and averaged footprints during high CO₂ cases confirmed that air particles mainly originated from eastern and north-eastern China, and inland of Korean Peninsula. In addition, it was revealed that among the cases of high CO₂ concentration, when the CO/CO₂ ratio is high, the industrial area of eastern China is greatly affected, and when the ratio is low, the contribution of the domestic region is relatively high. The ratio of CO₂ and CO in this study is significant in that it can be used as a useful factor in determining the possibility of domestic and foreign origins of climate pollutants.

• The Journal of the Convergence on Culture Technology
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• v.7 no.4
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• pp.785-789
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• 2021

Paprika productivity is different even in the same quality greenhouse and in the same region. These differences are known to due to differences in various environmental factors. This study was conducted to investigate the difference in the level of various environmental factors between high-productivity (HPF) and low-productivity (LPF) greenhouses. The largest difference between the two greenhouses in the daily or weekly average values of major environmental factors was the CO₂ concentration, but the LPF was higher than the HPF, so it was not determined as a factor for the difference in productivity. Correlation analysis among 14 environmental factors showed a high correlation among irradiation or related factors in moisture. The regression coefficients of the linear regression model between vapor pressure deficit and relative humidity were -0.0202kpa in HPF and -0.0262kpa in LPF. In particular, in February and March, the vapor pressure deficit in LPF was 1.5kpa or more, and the cumulative vapor pressure deficit compared to the cumulative irradiation at the early period of cultivation increased rapidly. The reason for the low productivity in LPF is thought to be that the plant was affected by moisture stress due to high vapor pressure deficit and transpiration under low irradiation conditions in the early period of cultivation and in winter.

• Journal of Industrial Convergence
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• v.20 no.5
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• pp.111-123
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• 2022

The purpose of this study is to investigate the influences of leisure satisfaction and burnout on job satisfaction of clinical nurses. The Data were collected the questionnaires consisted of general characteristics, leisure-related characteristics, leisure satisfaction, and burnout, and job satisfaction. For leisure satisfaction, the relaxation factor(16.57±2.68) was the highest among the sub-domains, and physical exhaustion(23.50±3.42) was the most severe for burnout. Leisure satisfaction and job satisfaction showed a positive correlation(r=.16, p=.013), and leisure satisfaction and burnout showed a negative correlation (r=-.19, p=.003). As factors related to job satisfaction, burnout(β=-0.68, p<.001) and ER(β=-0.12, p=.014) were found, and the total explanatory power was 47.0%, of which 44.0% was burnout. The model was found to be statistically significant(F=52.26, p<.001). The results of the study were as follows, a plan to improve leisure activities and leisure satisfaction is needed to reduce burnout. Through this, we aim to help improve the quality of life of clinical nurses.