• Journal of Korean Neurosurgical Society
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• v.64 no.5
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• pp.693-704
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• 2021

Objective : Endovascular mechanical thrombectomy (MT) has been regarded as one of the standard treatments for acute ischemic stroke caused by large vessel occlusion. Despite the wide use of stent retrievers for MT, arterial intimal damage caused when deployed stent is pulled has been a certain disadvantage. We hypothesized that statin could protect and stabilize vessel damage after endovascular MT using a stent retriever. In this animal study, we observed the protective effects of the statins towards MT-induced vessel wall injury. Methods : Twenty-eight carotid arteries of fourteen rabbits were used in the experiments with MT using stent retriever. We divided the rabbits into four groups as follows : group 1, negative control; group 2, positive control; group 3, statin before MT; and group 4, statin after MT. After MT procedures, we harvested the carotid arteries and performed histomorphological and immunohistochemical analyses. Results : In histomorphological analysis with hematoxylin and eosin and Masson's trichrome stain, significant intimal thickening (p<0.05) was observed in the positive control (group 2), compared to in the negative control (group 1). Intimal thickening was improved in the statin-administered groups (groups 3 and 4 vs. group 2, p<0.05). We also observed that statin administration after MT (group 4) resulted in a more effective decrease in intimal thickness than statin administration before MT (group 3) (p<0.05). We performed immunohistochemical analysis with the antibodies for tumor necrosis factor-alpha (TNF-α), cluster of differentiation (CD)11b, and CD163. In contrast to the negative control (group 1), the stained percentage areas of all immunological markers were markedly increased in the positive control (group 2) (p<0.05). Based on statin administration, the percentage area of TNF-α staining was significantly reduced (p<0.05) in group 3, compared to the positive control group (group 2). However, significant differences were not observed for CD11b and CD163 staining. In group 4, no significant differences were observed for TNF-α, CD11b, and CD163 staining (p≥0.05). The differences in the percentage areas of the different markers between the statin-administered groups (groups 3 and 4) were also not revealed. Conclusion : We presented that statin administration before and after MT exerted protective effects towards vessel wall injury. The efficacy of statins was greater post-administration than pre-administration. Thus, statin administration in routine prescriptions in the peri-procedural period is strongly advised.

• The Journal of the Korea Contents Association
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• v.21 no.5
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• pp.794-807
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• 2021

The purpose of this study is to examine the effect of family poverty on the school adjustment of multi-cultural adolescents in Korea. For this purpose, the 7th data of Multi-cultural Adolescents Panel Study(MAPS) was used and the OLS multiple regression models ware applied. to the analyses. From the result of the OLS model analyses, we found out that family poverty affect significantly on the school adjustment of multi-cultural adolescents. Especially, family poverty has the significant negative(-) effects on academic achievement and friend relationships. These results of this study show that family poverty is an important factor influencing the school adjustment of multi-cultural adolescents. And they confirm that family poverty during period of the adolescent has an important meaning and influence on the aspect of school adjustment as to the multi-cultural adolescents. Implications of this study may be that policy attentions are necessary to not only multi-cultural characteristics but also family background such as poverty in oder to improve the school adjustment of the multi-cultural adolescents. In addition, results of this study suggest that more special support and interventions are requested to the multi-cultural adolescents from poverty families who are suffering dual difficulties such as multi-cultural problems and poverty problem.

• Journal of the Korean GEO-environmental Society
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• v.23 no.2
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• pp.13-23
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• 2022

The ground-structure interaction of the bridge foundation has been pointed out as a major factor influencing the behavior of the bridge during earthquakes. In this study, the effect of characteristics of ground and bridge foundation on the earthquake vulnerability is investigated. From the pseudo-static analysis, it is confirmed that non-linearity becomes lesser and horizontal load becomes greater when surcharge is considered. It is also found that as the ground worsens and the size of foundation decreases, horizontal load reduces. To derive reasonable structural model for bridge foundation, fragility curve is obtained considering four conditions (fixed condition, equivalent linear condition, non-linear without surchage condition, non-linear with surcharge condition) and compared. Seismic analysis is performed on single pier with Opensees. From the earthquake vulnerability analysis, it is found that shallow foundation can be assumed as fixed condition. In conservative approach, stiffness of spring can be obtained based on Korean highway bridge design code for pile foundation which can consider the ground condition.

• Journal of Digital Convergence
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• v.20 no.4
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• pp.469-482
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• 2022

The purpose of this study is to analyze regional variation factors of hypertension treatment rate in COVID-19 based on the analysis results based on ecological methodology. To this end, data suitable for ecological analysis were collected from the Korea Centers for Disease Control and Prevention's regional health statistics, local government COVID-19 confirmed cases, National Health Insurance Corporation, Health Insurance Review and Assessment Service's welfare statistics, and Korea Transport Institute's traffic access index. Descriptive statistics and correlation analysis were conducted using SPSS Statistics 23 for regional variation and related factors in hypertension treatment rate, and geographical weighted regression analysis was conducted using Arc GIS for regional variation factors. As a result of the study, the overall explanatory power of the calculated geo-weighted regression model was 27.6%, distributed from 23.1% to 33.4% by region. As factors affecting the treatment rate of hypertension, the higher the rate of basic living security medical benefits, diabetes treatment rate, and health institutions per 100,000 population, the higher the rate of hypertension treatment, the lower the number of COVID-19 confirmed patients, the lower the rate of physical activity, and the alcohol consumption. Percentage of alcohol consumption decreased due to COVID-19 pandemic. It was analyzed that the lower the ratio, the higher the treatment rate for hypertension. Based on these results, the analysis of regional variables in the treatment rate of hypertension in COVID-19 can be expected to be effective in managing the treatment rate of hypertension, and furthermore, it is expected to be used to establish community-centered health promotion policies.

• Journal of Korean Neurosurgical Society
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• v.65 no.4
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• pp.558-571
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• 2022

Objective : The primary objective of this study was to identify predicting factors for local control (LC) of atypical meningioma, and we validated them with comparing the predicting factors for recurrence-free survival (RFS). We also examined the rate of LC after surgical resection with or without adjuvant treatment and RFS. Methods : Clinical and radiological records of patients with atypical meningiomas diagnosed at two institutes from January 2000 to December 2018 were reviewed retrospectively. Histopathological features were also reviewed using formalin-fixed paraffin embedded samples from pathological archives. Results : Of the 99 atypical meningiomas eligible for analysis, 36 (36.4%) recurred during the follow-up period (mean, 83.3 months; range, 12-232 months). The rate of 3-year LC and 5-year LC was 80.8% and 74.7%, respectively. The mean time-to-recurrence was 49.4 months (range, 12-150). The mean RFS was 149.3 months (95% confidence interval, 128.8-169.8 months) during the mean follow-up duration of 83.3 months (range, 12-232 months). Multivariate analysis using Cox proportional-hazard regression model showed that the extent of resection (hazard ratio [HR], 4.761; p=0.013), Ki67 index (HR, 8.541; p=0.004), mitotic index (HR, 3.275; p=0.044), and tumor size (HR, 3.228; p=0.041) were independently associated with LC. These factors were also statistically associated with RFS. In terms of radiotherapy after surgical resection, the recurrence was not prevented by immediate radiotherapy because of the strong effect of proliferative index on recurrence. Conclusion : The present study suggests that the extent of resection, proliferative index (according to Ki67 expression) and mitotic index, and tumor size are associated with recurrence of atypical meningiomas. However, our results should be further validated through prospective and randomized clinical trials to overcome the inborn bias of retrospective nature of the study design.

• Land and Housing Review
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• v.13 no.1
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• pp.23-38
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• 2022

As city tourism has recently been evaluated as a major indicator of urban competitiveness, strengthening the role of cities as tourist destinations has received more attention. However, industrialization and urbanization of many cities lead to population decline, extinction of traditional industries, and deterioration of living environments, weakening urban functions and competitiveness. Thus, it is essential for declining cities to build a measure to restore urban competitiveness by enhancing urban functions. Accordingly, this study focused on socio-cultural urban regeneration by exploring physical spaces for tourism destinations in declining cities. Different from general tourist destinations, tourism destinations of urban regeneration have a temporal perspective covering the past, present, and future. How does the temporal perspective of urban regeneration tourist destinations affect tourists' satisfaction and behavioral intention? In order to address these questions, this study conducts an empirical analysis based on structural equation modeling (SEM) using the sample of tourists who have visited urban regeneration tourism destinations. With SEM, this paper investigates structural relationships across variables by testing the hypothesis established in the proposed research model. The results show that precious memories of the past are the most important factor for tourists to visit urban regeneration tourist destinations. The empirical findings of this study will contribute to the research areas of urban tourism, urban regeneration tourism, and urban regeneration tourism destinations. In addition, this study can provide practical implications to develop socio-cultural contents of urban regeneration areas as tourism resources to establish plans for urban regeneration projects and achieve sustainable development strategies.

• The Journal of the Korea Contents Association
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• v.22 no.6
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• pp.580-595
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• 2022

This study looked at the relationship between lifestyle choices and various substance addictions in young adults by applying the Relapse Prevention model of addiction. The data was obtained from a cross-sectional questionnaire (Depression and Anxiety Assessment Test) of 926 young adults aged 18~24 from 24 countries. Of these, 17.6% reported that they had a serious substance addiction, with alcohol addiction being the highest (11.2%), followed by nicotine (10.3%) and illicit drug (8.7%) usage. Results of chi-square test and logistic regression analysis revealed a significant association between various lifestyle factors (exercise patterns, intake of dietary nutrients like tryptophan, folic acid, omega-3 fatty acids and micronutrients, spiritual habits such as Bible reading and prayer) and addiction to various substances (illicit drugs, alcohol and nicotine). Depression was also found to be a significant factor influencing substance addiction. Interestingly, the risk of alcohol abuse was the highest at 9.870 (95% CI: 4.525-21.525) times among those who didn't have the habit of daily Bible reading. The highest risk of nicotine and illicit drug addiction was among those who consumed 'less than 1 serving' of dietary micronutrients per day compared to those who consumed '5 or more servings', with odds ratios of 9.606(95% CI: 2.726-30.111) and 8.642(95% CI: 2.022-37.378), respectively. These findings suggest that holistic lifestyle interventions may help prevent and reduce substance addiction in young adults.

• Journal of Korea Entertainment Industry Association
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• v.15 no.2
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• pp.159-167
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• 2021

The main purpose of this study is to closely investigate the constructive relationship between leisure satisfaction, leisure ability, exercise satisfaction, and consistent motor behavior patterns of the elderly's participation in leisure life sports. In order to achieve this, we surveyed and utilized the sampling of conveniences that selected Yongin and Seongnam city in Gyeonggi-do sports clubs, and accumulated samples of the elderly in living sports. The sample size was 239 elderly people. Based on this, according to the purpose of the study, statistical techniques, spss 23.0, and amos programs were used for analysis. The satisfaction analysis used in the research for a data analysis includes frequency analysis, exploatory factor analysis, confirmatory facor analysis, reliability analysis, correnlation analysis and structure equation model analysis. The research has drawn the following conclusions, based on the above mentioned research method and its procedures: First, it affects the satisfaction of the leisure satisfaction movement. Second, leisure ability affects exercise satisfaction. Third, exercise satisfaction affects the consistent exercise persistence and immersion satisfaction of exercise. As a result, it can be seen that the leisure immersion according to the experience of leisure competence has an effect on the satisfaction of the exercise. As a result, and the continuation of the exercise.

• Applied Chemistry for Engineering
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• v.33 no.6
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• pp.636-645
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• 2022

In this study, we investigated the adsorption characteristics of methyl orange (MO), an anionic dye, on ginkgo shell-based activated carbon (AC). For this purpose, ACs (GS-1, GS-2, and GS-4) with different textural properties were prepared using ginkgo shells and potassium hydroxide (KOH), a representative chemical activating agent. The correlation between the textural characteristics of AC prepared and the mixing ratio of KOH was investigated using nitrogen adsorption/desorption isotherms. The MO adsorption equilibrium experiment on the prepared ACs was conducted under different pH (pH 3~11) and temperature (298~318 K) conditions, and the results were investigated by Langmuir, Freundlich, Sips and temperature-dependent Sips equations. The feasibility of the MO adsorption treatment process of the prepared AC was also investigated using the dimensionless Langmuir separation factor. The heterogeneous adsorption properties of MO for the prepared AC examined using the adsorption energy distribution function (AED) were closely related to the system temperature and textural characteristics of AC. The kinetic results of the batch adsorption performed at different temperatures can be satisfactorily explained by the homogeneous surface diffusion model (HSDM), which takes into account the external mass transfer, intraparticle diffusion, and active site adsorption. The relationship between the activation energy value obtained by the Arrhenius plot and the adsorption energy distribution function value was also investigated. In addition, the adsorption process mechanism of MO on the prepared AC was evaluated using Biot number.

• 한국노년학
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• v.40 no.1
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• pp.163-178
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• 2020

The purpose of this study is to analyze leisure factors affect happiness of the elderly by sex in Korea and then to discuss implications for the findings. Data of National Leisure Activity Survey conducted by Korea Culture & Tourism Institute in 2016 were used for this study. From this dataset, 891 male elderly and 970 female elderly aged above 65 were selected for this study. Ordered logistic regression model was used by considering the nature of the dependent variable. The results of this study can be summarized as follows. First, choice proportions of leisure activities classified by four type are different by sex of the elderly. Second, among control variables, household income, residential area, joining a club have different significant effect on happiness of the elderly by sex but volunteering have same significant effect on happiness of the elderly by sex. Third, any type of leisure activity have no significant effect on happiness of both the male elderly and the female elderly. Fourth, cost of leisure has significant positive effect on happiness of both the male elderly and the female elderly but has different significance by sex. Fifth, focus on leisure rather than work has very significant positive effect on happiness of both the male elderly and the female elderly. Sixth, leisure life satisfaction has very significant positive effect on happiness of both the male elderly and the female elderly.