• Journal of Korean Society of Environmental Engineers
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• v.31 no.9
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• pp.825-830
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• 2009

Pharmaceutical compounds enter the water environment through the diverse pathways. Because their concentration in the water environment was frequently detected in the level of ppt to ppb, the monitoring system should be optimized as much as possible for finding appropriate management policies and technical solutions. One Factor At a Time (OFAT) approach approximating the response with a single variable has been preferred for the optimization of LC-MS/MS operational conditions. However, it is common that variables in analytical instruments are interdependent. Therefore, the best condition could be found by using the statistical optimization method changing multiple variables at a time. In this research, response surface analysis (RSA) was applied to the LC-MS/MS analysis of emerging antibiotic compound, sulfamethoxazole, for the best sensitivity. In the screening test, fragmentation energy and collision voltage were selected as independent variables. They were changed simultaneously for the statistical optimization and a polynomial equation was fit to the data set. The correlation coefficient, $R^2$ valuerepresented 0.9947 and the error between the predicted and observed value showed only 3.41% at the random condition, fragmentation energy of 60 and collision voltage of 17 eV. Therefore, it was concluded that the model derived by RSA successfully predict the response. The optimal conditions identified by the model were fragmentation energy of 116.6 and collision voltage of 10.9 eV. This RSA can be extensively utilized for optimizing conditions of solid-phase extraction and liquid chromatography.

• Journal of the Korean Society of Groundwater Environment
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• v.4 no.1
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• pp.14-19
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• 1997

Laboratory experiments were conducted to study the effects of pH and salt level on the soil sorption equilibrium of pentachlorophenol (PCP) which is hydrophobic and ionogenic. Experimental results indicated that the sorption equilibrium constant (Kp) of PCP increased with decreasing pH. A quantitative sorption model involving linear isotherms was estabilished to predict the pH effect on the PCP sorption equilibrium over the pH range from 3 to 8. The model prediction was in good agreement with the experimental data. Also, the Kp increased with salt concentration over the entire pH range. At added salt levels less than 0.1M, increase in Kp was larger than when the added levels were higher than 0.1M. Salt might increase the PCP sorption by inducing 'salting out-effect' or by forming deprotonated PCP-cation ion pairs such as PCP$\^$-/K$\^$＋/. Taking the pH range (5-8) and the salt content (up to 50 g/L) in the groundwater of Metropolitan landfill sites into consideration, the results indicated that the retardation factor of PCP in this area might range from 3 to 550 depending upon pH and salt content.

• Journal of Preventive Medicine and Public Health
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• v.13 no.1
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• pp.3-12
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• 1980

Certain heavy metals which may lead peoples to poisonous status are widely used in industry and their uses have been increasing along with rapid industrialization of this country. Such an increasement of metal uses aggravates the status of environmental pollution affecting foodstuffs which are the most important life supporting factor of animal and humanbeing. Concerning the safety measures to minimize food-borne transmission of such hazardous metals, surveillance is the backbone of them and probably more so with a potential problem such as intoxication. Theoretically, this surveillance should include the determination of levels of heavy metal toxicants in foods, the determination of food consumption patterns and typical total diet, and the estimation of total load of the metal contaminant from all sources of exposure including air, water, and occupational sources. In recent year, actually, such estimates on the total daily intake of some heavy metals from foods have been made in several developed countries and a wide variation of date by season, locality, and research method was recognized. Also in this country, this kind of research data is vitally needed to make up for the serious shortage or lack of references to estimate the total amount of heavy metal intake of the people. In this study, a modification model for estimation of the total daily intake of cadmium copper, nickel, zinc, and lead through foods was applied and concentrations of the above metals in crops cultivated in this country were measured with atomic absorption spectro photometer to get the following results. 1. Level of heavy metal concentration in crops Generally, the levels of such metals in essential crops such as rice, cucumber, radish. chinese cabbage, apple, pear, grape, and orange are similar or lower than those in Japan and other developed countries. By the way, a striking result on cadmium concentration was increasement of its concentration in rice from $0{\sim}0.035ppm$ in 1970 to 0.11ppm in this study. However, the value is still far below the. Japanese Permissible Lebel of 1.0ppm. 2. Estimation of total daily intake per capita from foods A new model for estimation was devised utilizing levels of metal concentration in foods, amount of food consumed, and other food factors. Based on the above method, the daily intake of cadmium was estimated to be $70.53{\mu}g/man/day$ in average which was as high as the Limit Value of ILO/WHO(up to $71.4{\mu}g/man/day$). Also, 3.89mg of Zinc, 1.65mg of cuppor, 0.32mg of lead were given as the total daily intake per capita by this research. 3. Efficacy of washing or skinning to decrease the amount of metals in crops After washing the crops sufficiently with commercial linear alkylate sulfonate, the concentration of heavy metals could be reduced to $50{\sim}80%$ showing decreasement rate of $20{\sim}50%$. Also, after skinning the fruits, decreasement rate of the heavy metal concentration shelved $0{\sim}50%$.

• Journal of muscle and joint health
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• v.5 no.2
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• pp.174-190
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• 1998

Osteoporosis has been known as a common complication of rheumatoid arthritis and a major preventable health problem. Lots of studios have demonstrated that changes in life style can help delay or prevent osteoporosis. Therefore nursing intervention related osteoporosis prevention have consisted of education programs aimed at changing dietary and exercise habit. However knowledge gained from education haven't always leaded to behavior change. Therefore it is important to consider other psychological variables in effecting behavior change. Numerous research have found self efficacy and health belief to be an important factor in individual decision making behavior. The purpose of the study was to develop health belief and efficacy expectation promoting program based on Health Belief Model & Self Efficacy Model and to investigate its effects in women with rheumatoid arthritis. For this purpose, one group pretest-post design was used. The subject of the study were 16 women with rheumatoid arthritis in Pusan city and data collection was carried out from April, 1997 to May, 1998. The intervention program was consisted of educating on osteoporosis and enhancing and reinforcing self efficacy by verbal persuasion during the period of 4 weeks. The instruments were used to collect data in this study were Osteoporosis Health Belief Scale, Osteoporosis Self Efficacy Scale, and Osteoporosis Preventive Behavior Scale. Data was analyzed by Wilcoxon signed rank test using SPSS $PC^+$ program. The results are as follows : 1) The behavior should be increased after intervention was supported(Z=-3.5162, p=.0004, diet : Z=-3.2942, p=.0010, exercise). 2) The sub-hypothesis that perceived sensitivity should be increased after intervention was supported (Z=-2.3854, p=.0171). 3) The sub-hypothesis that perceived severity should be increased after intervention was rejected(Z=-1.4327, p=.1520). 4) The sub-hypothesis that perceived benefit should be increased after intervention was supported(Z=-2.6410, p=.0083). 5) The sub-hypothesis that perceived barrier should be decreased after intervention was supported (Z=-2.4138, p=.0158). 6) The sub-hypothesis that efficacy expectation should be increased after intervention was supported(Z=-3.5162, p=.0004). As a conclusion, it was found that health belief and self efficacy promoting program was an effective nursing intervention for preventing osteoporosis of rheumatoid arthritis.

• Journal of the Korea Concrete Institute
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• v.23 no.2
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• pp.245-252
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• 2011

Currently, the design guidelines for the prevention of progressive collapse are not available in Korea due to the lack of study efforts in progressive collapse resistance evaluation of RC flat plate system. Therefore, in this study, three types of analysis were conducted to evaluate the progressive collapse resistance of a RC flat plate system. A linear static analysis was carried out by comparing the demand-capacity ratio (DCR) differences of the systems using the alternate load path method, which is the guideline of GSA. A dynamic behavior was investigated by checking the vertical deflection after removal of the column using the linear dynamic analysis. Lastly, a maximum load factor was investigated using the nonlinear static analysis. The finite element (FE) analyses were conducted using various parameters to analyze the results obtained using effective beam width (EB) model and plate element FEM (PF) model. This study results showed that the strength contributions of the slab in the EB models are underestimated compared to those obtained from the PF models. Therefore, a detailed FE analysis considering the slab element is required to thoroughly estimate the progressive collapse resisting capacity of flat plate system. The scenario of the corner column (CC) removal is the most dangerous conditions where as the scenario of the inner column (IC) removal is the least dangerous conditions based on the consideration of various parameters. The analysis results will allow more realistic evaluations of progressive collapse resistance of RC flat plate system.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.25 no.1
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• pp.85-105
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• 2014

The purpose of this study is to identify the factors that influence users' intention to use mobile services in academic libraries, based on the Davis' Technology Acceptance Model. This study employed both perceived usefulness and perceived ease of use, which were core variables in TAM, and added perceived playfulness that was recently applied to many researches on mobile system acceptance intention. As external variables, ubiquitous ability, context awareness, and mobile internet self-efficacy were employed. The data was collected from 325 surveys from two academic libraries and was analyzed with SPSS 18.0 and AMOS 21.0. As a result, perceived usefulness was the most significant factor in predicting users' acceptance intention and perceived ease of use was an indirect determinant of service usage. But perceived playfulness was not significantly correlated. Ubiquitous ability among external variables had a significant effect on perceived usefulness, context awareness did on both perceived playfulness and ease of use, and mobile internet self-efficacy did on perceived ease of use. Based on the findings, this study discussed theoretical and practical implications in academic library mobile service area.

• Journal of Families and Better Life
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• v.19 no.4
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• pp.49-68
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• 2001

The purpose of this study was 1) to review communal housing in the UK, 2) to consider the policy implications for elderly communal housing in Korea. The research methods used were 1) literature review about communal housing and related policy in the UK 2) field survey in the UK 3) interpretative suggestion for the proper policy implication to develope communal housing for the elderly in Korea. Sheltered housing in the UK had been developed as communal housing for the elderly with special needs since the 1970s. The type of sheltered housing were category 1 and category 2. Very sheltered housing with more facilities and meal services was added in 1980s. Sheltered housing was evaluated as the most humanistic solution for older people in the UK in 1980s. Because of the policy of moving institutional care to community care, sheltered housing became less in demand because of more options for older people including being able to stay in their own home. So new completion of sheltered housing by registered social landlords reduced saliently. Sheltered housing already totalled over half million units in which 5% of all elderly over 65 still lived and a small quantity of private sector for sale schemes emerged in the 1990s. The reason why the residents moved to sheltered housing was for sociable, secure, and manageable living arrangements. In general the residents were satisfied with these characteristics but dissatisfied with the service charge and quality of meals, especially in category 2.5 schemes. The degree of utilisation of communal spaces and facilities depended on the wardens ability and enthusiasm. Evaluation of sheltered housing indicated several problems such as wardens duty as a \"good neighbour\" ; difficult-to-let problems with poor location or individual units of bedsittiing type with shared bathroom ; and the under use of communal spaces and facilities. Some ideas to solve these problems were suggested by researchers through expanding wardens duty as a professional, opening the scheme to the public, improving interior standards, and accepting non-elderly applicants who need support. Some researchers insisted continuing development of sheltered housing, but higher standards must be considered for the minority who want to live in communal living arrangement. Recently, enhanced sheltered housing with greater involvement of relatives and with tied up policy in registration and funding suggested as an alternative for residential care. In conclusion, the rights of choice for older people should be policy support for special needs housing. Elderly communal housing, especially a model similar to sheltered housing category 2 with at least 1 meal a day might be recommended for a Korean Model. For special needs housing development either for rent or for sale, participation of the public sector and long term and low interest financial support for the private sector must be developed in Korea. Providing a system for scheme managers to train and retrain must be encouraged. The professional ability of the scheme manager to plan and to deliver services might be the most important factor for the success of elderly communal housing projects in Korea. In addition the expansion of a public health care service, the development of leisure programs in Senior Citizens Centre, home helper both for the elderly in communal housing and the elderly in mainstream housing of the community as well. Providing of elderly communal housing through the modified general Construction Act rather than the present Elderly Welfare Act might be more helpful to encourage the access of general people in Korea. in Korea.

• Korean Journal of Construction Engineering and Management
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• v.16 no.4
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• pp.118-128
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• 2015

Recently BIM technology has been expanded for using in construction project. Due to the high-cost of BIM infrastructure development, lack of regulations, lack of process and so forth, usage of BIM has been delayed than initial expectations. In design phase, especially, collaboration based on BIM system has been a key factor for successful next generation building project. Through the analysis of current research trends about IT technologies, virtualization and BIM service, data exchange such as drawings, 3D model, object data, properties using cloud computing and virtual server system is defined as a most successful solution. The purpose of this study is to enable the cloud computing BIM server to provide several main functions such as editing models, 3D model viewing and checking, mark-up and snapshot in high-performance quality by proper design of VDI system. Concurrent client connection performance is a main technical index of VDI. Through testing of test-bed server client, developed VDI system's multi-connect control is evaluated. Performance-test result of BIM server VDI effect to development direction of cloud computing BIM service for commercialization.

• BMB Reports
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• v.48 no.3
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• pp.178-183
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• 2015

Dendritic cells play an important role in determining whether na${\ddot{i}}$ve T cells mature into either Th1 or Th2 cells. We determined whether heat-shock protein X (HspX) purified from Mycobacterium tuberculosis regulates the Th1/Th2 immune response in an ovalbumin (OVA)-induced murine model of asthma. HspX increased interferon-gamma, IL-17A, -12 and transforming growth factor (TGF)-${\beta}$ production and T-bet gene expression but reduced IL-13 production and GATA-3 gene expression. HspX also inhibited asthmatic reactions as demonstrated by an increase in the number of eosinophils in bronchoalveolar lavage fluid, inflammatory cell infiltration in lung tissues, airway luminal narrowing, and airway hyper-responsiveness. Furthermore, HspX enhanced OVA-induced decrease of regulatory T cells in the mediastinal lymph nodes. This study provides evidence that HspX plays critical roles in the amelioration of asthmatic inflammation in mice. These findings provide new insights into the immunotherapeutic role of HspX with respect to its effects on a murine model of asthma.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.32 no.6D
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• pp.549-556
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• 2012

Longitudinal tunnels are defined as tunnels with length of over 1km. Because of Korea's topographical conditions and as safety measures for linear design, many tunnels are inevitably being constructed in Korea. The number of longitudinal tunnels constructed on expressways amounted to 104 as of the end of 2010 with a total length of 192km. Given the increasing demand for tunnels and the increasing length of tunnels, a safety evaluation of longitudinal tunnels needs to be conducted. As such, this study selected design elements, transportation environment and delineation system as elements to check and tried to determine factors influencing road crashes. For this, tunnels have been classified based on history of crashes; ones with crashes and ones without crashes and statistically meaningful explanatory variables were selected. By using these variables, a logit model was development in order to better grasp the factors that directly and strongly influence crashes. The result, related to crashes as well as the analysis were utility tunnel interior materials of driving lane and passing lane, which are related to driver's visibility, lateral width widening to consolidate space in a tunnel, and annual average daily traffic (AADT) per lane. These results may be used in the future as analysis indicators when drawing up plans to prevent crashes in longitudinal tunnels.