• Title/Summary/Keyword: model factor

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Effect of different voxel sizes on the accuracy of CBCT measurements of trabecular bone microstructure: A comparative micro-CT study

  • Tayman, Mahmure Ayse;Kamburoglu, Kivanc;Ocak, Mert;Ozen, Dogukan
    • Imaging Science in Dentistry
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    • v.52 no.2
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    • pp.171-179
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    • 2022
  • Purpose: The aim of this study was to assess the accuracy of cone-beam computed tomographic (CBCT) images obtained using different voxel sizes in measuring trabecular bone microstructure in comparison to micro-CT. Materials and Methods: Twelve human skull bones containing posterior-mandibular alveolar bone regions were analyzed. CBCT images were obtained at voxel sizes of 0.075mm(high: HI) and 0.2mm(standard: Std), while microCT imaging used voxel sizes of 0.06 mm (HI) and 0.12 mm (Std). Analyses were performed using CTAn software with the standardized automatic global threshold method. Intraclass correlation coefficients were used to evaluate the consistency and agreement of paired measurements for bone volume (BV), percent bone volume (BV/TV), bone surface (BS), trabecular thickness (TbTh), trabecular separation (TbSp), trabecular number (TbN), trabecular pattern factor(TbPf), and structure model index (SMI). Results: When compared to micro-CT, CBCT images had higher BV, BV/TV, and TbTh values, while micro-CT images had lower BS, TbSp, TbN, TbPf, and SMI values (P<0.05). The BV, BV/BT, TbTh, and TbSp variables were higher with Std voxels, whereas the BS, TbPf, and SMI variables were higher with HI voxels for both imaging methods. For each imaging modality and voxel size evaluated, BV, BS, and TbTh were significantly different(P<0.05). TbN, TbPf, and SMI showed statistically significant differences between imaging methods(P<0.05). The consistency and absolute agreement between micro-CT and CBCT were excellent for all variables. Conclusion: This study demonstrated the potential of high-resolution CBCT imaging for quantitative bone morphometry assessment.

Antidepressant-like effect of ginsenoside Rb1 on potentiating synaptic plasticity via the miR-134-mediated BDNF signaling pathway in a mouse model of chronic stress-induced depression

  • Wang, Guoli;An, Tianyue;Lei, Cong;Zhu, Xiaofeng;Yang, Li;Zhang, Lianxue;Zhang, Ronghua
    • Journal of Ginseng Research
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    • v.46 no.3
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    • pp.376-386
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    • 2022
  • Background: Brain-derived neurotrophic factor (BDNF)-tropomyosin-related kinase B (TrkB) plays a critical role in the pathogenesis of depression by modulating synaptic structural remodeling and functional transmission. Previously, we have demonstrated that the ginsenoside Rb1 (Rb1) presents a novel antidepressant-like effect via BDNF-TrkB signaling in the hippocampus of chronic unpredictable mild stress (CUMS)-exposed mice. However, the underlying mechanism through which Rb1 counteracts stress-induced aberrant hippocampal synaptic plasticity via BDNF-TrkB signaling remains elusive. Methods: We focused on hippocampal microRNAs (miRNAs) that could directly bind to BDNF and are regulated by Rb1 to explore the possible synaptic plasticity-dependent mechanism of Rb1, which affords protection against CUMS-induced depression-like effects. Results: Herein, we observed that brain-specific miRNA-134 (miR-134) could directly bind to BDNF 30 UTR and was markedly downregulated by Rb1 in the hippocampus of CUMS-exposed mice. Furthermore, the hippocampus-targeted miR-134 overexpression substantially blocked the antidepressant-like effects of Rb1 during behavioral tests, attenuating the effects on neuronal nuclei-immunoreactive neurons, the density of dendritic spines, synaptic ultrastructure, long-term potentiation, and expression of synapse-associated proteins and BDNF-TrkB signaling proteins in the hippocampus of CUMS-exposed mice. Conclusion: These data provide strong evidence that Rb1 rescued CUMS-induced depression-like effects by modulating hippocampal synaptic plasticity via the miR-134-mediated BDNF signaling pathway.

The Relation between Management Efficiency and Financial Performance in Public Institutions

  • Jang, Ji-Kyung
    • Journal of the Korea Society of Computer and Information
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    • v.27 no.4
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    • pp.161-167
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    • 2022
  • This study aims to analyze the relation between management efficiency and financial performance in public institutions. Based on 135 public institutions published in public business information system from 2017 to 2020, Data Envelopment Analysis(DEA) for estimating management efficiency was performed. This study analyzed the relationship between DEA and financial performance included ROA and ROS using multi-regression analysis. The results of this study are as follows; We find that there is significant positive relation between management efficiency and ROA. We also find this significant relation in model with ROS. This finding implies that management efficiency a factor that improve financial performance in public institutions. The results of this study can provide an important empirical evidence for evaluating the strategy of governance to improve financial performance by enhancing management efficiency.

RELATION BETWEEN BLACK HOLE MASS AND BULGE LUMINOSITY IN HARD X-RAY SELECTED TYPE 1 AGNS

  • Son, Suyeon;Kim, Minjin;Barth, Aaron J.;Ho, Luis C.
    • Journal of The Korean Astronomical Society
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    • v.55 no.2
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    • pp.37-57
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    • 2022
  • Using I-band images of 35 nearby (z < 0.1) type 1 active galactic nuclei (AGNs) obtained with Hubble Space Telescope, selected from the 70-month Swift-BAT X-ray source catalog, we investigate the photometric properties of the host galaxies. With a careful treatment of the point-spread function (PSF) model and imaging decomposition, we robustly measure the I-band brightness and the effective radius of bulges in our sample. Along with black hole (BH) mass estimates from single-epoch spectroscopic data, we present the relation between BH mass and I-band bulge luminosity (MBH-MI,bul relation) of our sample AGNs. We find that our sample lies offset from the MBH-MI,bul relation of inactive galaxies by 0.4 dex, i.e., at a given bulge luminosity, the BH mass of our sample is systematically smaller than that of inactive galaxies. We also demonstrate that the zero point offset in the MBH-MI,bul relation with respect to inactive galaxies is correlated with the Eddington ratio. Based on the Kormendy relation, we find that the mean surface brightness of ellipticals and classical bulges in our sample is comparable to that of normal galaxies, revealing that bulge brightness is not enhanced in our sample. As a result, we conclude that the deviation in the MBH-MI,bul relation from inactive galaxies is possibly because the scaling factor in the virial BH mass estimator depends on the Eddington ratio.

The Effect of Selective Exposure of Political Orientation on Online Political Participation: Focusing on the Mediating Effect of Attitude Polarization (유튜브 정치성향에 따른 선택적 노출이 온라인 정치참여에 미치는 영향: 태도극화의 매개효과를 중심으로)

  • Lee, Min Kyu;Kim, Jung Hoon
    • The Journal of the Korea Contents Association
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    • v.22 no.4
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    • pp.261-272
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    • 2022
  • This study investigated the relationship between selective exposure, attitude polarization, and online political participation among 420 YouTube political video users. Additionally, the mediating effect of attitude polarization on the relationship between selective exposure and online political participation was examined. The main results were derived by conducting exploratory factor analysis, correlation analysis, and structural model analysis using the SPSS 21.0 program and AMOS 21.0 program. The results were presented as follows. First, selective exposure had a positive effect on attitude polarization. Second, selective exposure had a positive effect on online political participation. Third, attitude polarization had a positive effect on online political participation. Fourth, attitude polarization was found to mediate the relationship between selective exposure and online political participation. In summary, it was confirmed that selective exposure to YouTube political videos increased attitude polarization and online political participation, and the more the attitude polarization was strengthened by selective exposure, the more it led to online political participation.

Jacobian-free Newton Krylov two-node coarse mesh finite difference based on nodal expansion method

  • Zhou, Xiafeng
    • Nuclear Engineering and Technology
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    • v.54 no.8
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    • pp.3059-3072
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    • 2022
  • A Jacobian-Free Newton Krylov Two-Nodal Coarse Mesh Finite Difference algorithm based on Nodal Expansion Method (NEM_TNCMFD_JFNK) is successfully developed and proposed to solve the three-dimensional (3D) and multi-group reactor physics models. In the NEM_TNCMFD_JFNK method, the efficient JFNK method with the Modified Incomplete LU (MILU) preconditioner is integrated and applied into the discrete systems of the NEM-based two-node CMFD method by constructing the residual functions of only the nodal average fluxes and the eigenvalue. All the nonlinear corrective nodal coupling coefficients are updated on the basis of two-nodal NEM formulation including the discontinuity factor in every few newton steps. All the expansion coefficients and interface currents of the two-node NEM need not be chosen as the solution variables to evaluate the residual functions of the NEM_TNCMFD_JFNK method, therefore, the NEM_TNCMFD_JFNK method can greatly reduce the number of solution variables and the computational cost compared with the JFNK based on the conventional NEM. Finally the NEM_TNCMFD_JFNK code is developed and then analyzed by simulating the representative PWR MOX/UO2 core benchmark, the popular NEACRP 3D core benchmark and the complicated full-core pin-by-pin homogenous core model. Numerical solutions show that the proposed NEM_TNCMFD_JFNK method with the MILU preconditioner has the good numerical accuracy and can obtain higher computational efficiency than the NEM-based two-node CMFD algorithm with the power method in the outer iteration and the Krylov method using the MILU preconditioner in the inner iteration, which indicates the NEM_TNCMFD_JFNK method can serve as a potential and efficient numerical tool for reactor neutron diffusion analysis module in the JFNK-based multiphysics coupling application.

Horizontal Wave Pressures on the Crown Wall of Rubble Mound Breakwater Under a Non-Breaking Condition: Effect of the Armour Crest Width (비쇄파조건에서 경사식방파제의 상치콘크리트에 작용하는 수평파압: 피복재 어깨폭 영향)

  • Lee, Jong-In;Lim, Ho Seok;Cho, Ji Hoon
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.42 no.4
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    • pp.469-480
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    • 2022
  • To design the crown wall of rubble-mound breakwaters, the horizontal wave load should be available, but determining this load remains difficult. Lee et al. proposed modification factors for Goda's formula for the horizontal wave pressures on acrown wall. The empirical formula by Lee et al. was based on a two-dimensional model test with a relatively narrow armour crest width in front of the crown wall. In this study, a series of experiments at the same facility were conducted on the horizontal wave pressures on the crown wall of a rubble-mound breakwater with a wide armour crest width. As a result, the pressures of the unprotected part of the crown wall were nearly identical to the narrow crest width. However, the pressures of the protected part tended to decrease with a change in the armour crest width. From the experimental results, the horizontal pressure modification factors of Goda's formula including the armour crest width effect are suggested here and are likely applicable to practical designs of the crown walls of rubble-mound breakwaters covered with tetrapods.

The Relationship between Supervision and Job Burnout of Workers in Leisure Welfare Centers for the Elderly: Mediation Effect of Self-efficacy (노인여가복지시설 종사자의 슈퍼비전과 직무소진의 관계에서 자아효능감의 매개효과)

  • Lee, Byoung-Rock
    • Journal of Digital Convergence
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    • v.20 no.4
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    • pp.661-666
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    • 2022
  • This study verified the influence of supervision on job burnout and mediating effect of self-efficacy of workers in leisure welfare centers for the elderly. A survey of 275 employees of 15 facilities of Daejeon and Chungnam area was conducted. Main analysis methods are confirmatory factor analysis and structural equation model analysis. The analysis result is that supervision influences job burnout and mediating effect of self-efficacy is proved. Considering the analysis result, some countermeasures can be proposed to alleviate the job burnout. For improving the supervision of workers, the strengthening of educational and evaluational supervision, the provision of education and training for supervisors and individualized supervision, and the inclusion of supervision in facility evaluation are necessary. To improve employees' self-efficacy, it is necessary to provide capacity-building programs and emotional support services, education and administrative support for improving ethical awareness, and self-leadership.

Sensitivity and uncertainty quantification of neutronic integral data in the TRIGA Mark II research reactor

  • Makhloul, M.;Boukhal, H.;Chakir, E.;El Bardouni, T.;Lahdour, M.;Kaddour, M.;Ahmed, Abdulaziz;Arectout, A.;El Yaakoubi, H.
    • Nuclear Engineering and Technology
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    • v.54 no.2
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    • pp.523-531
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    • 2022
  • In order to study the sensitivity and the uncertainty of the Moroccan research reactor TRIGA Mark II, a model of this reactor has been developed in our ERSN laboratory for use with the N-Particle MCNP Monte Carlo transport codes (version 6). In this article, the sensitivities of the effective multiplication factor of this reactor are evaluated using the ENDF/B-VII.0, ENDF/B-VII.1 and JENDL-4.0 libraries and in 44 energy groups, for the cross sections of the fuel (U-235 and U-238) and the moderator (H-1 and O-16). However, the quantification of the uncertainty of the nuclear data is performed using the nuclear code NJOY99 for the generation and processing of covariance matrices. On the one hand, the highest uncertainty deviations, calculated using the ENDFB-VII.1 and JENDL4.0 evaluations, are 2275, 386 and 330 pcm respectively for the reactions U235(n, f), $ U_{235}(n\bar{\nu})$ and H1(n, γ). On the other hand, these differences are very small for the neutron reactions of O-16 and U-238. Regarding the neutron spectra, in CT-mid plane, they are very close for the three evaluations (ENDF/B-VII.0, ENDF/B-VII.1 and JENDL-4.0). These spectra present two peaks (thermal and fission) around the energies 0.05 eV and 1 MeV.

Factors Associated With the Illness of Nursing Professionals Caused by COVID-19 in Three University Hospitals in Brazil

  • de Oliveira, Larissa Bertacchini;de Souza, Luana Mendes;de Lima, Fabia Maria;Fhon, Jack Roberto Silva;Puschel, Vilanice Alves de Araujo;Carbogim, Fabio da Costa
    • Safety and Health at Work
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    • v.13 no.2
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    • pp.255-260
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    • 2022
  • Background: The coronavirus disease 2019 (COVID-19) pandemic has demonstrated the importance of implementing strategic management that prioritizes the safety of frontline nurse professionals. In this sense, this research was aimed at identifying factors associated with the illness of nursing professionals caused by COVID-19 according to socio-demographic, clinical, and labor variables. Methods: A cross-sectional study was conducted in three Brazilian university hospitals with 859 nursing professionals, which include nurses, technicians, and nursing assistants, between November 2020 and February 2021. We present data using absolute and relative frequency. We used Chi-square test for hypothesis testing and multiple logistic regression for predictive analysis and chances of occurrence. Results: The rate of nursing professionals affected by COVID-19 was 41.8%, and the factors associated with contamination were the number of people in the same household with COVID-19 and obesity. Being a nurse was a protective factor when the entire nursing team was considered. The model is significant, and its variables represent 56.61% of the occurrence of COVID-19 in nursing professionals. Conclusion: Obesity and living in the same household as other people affected by COVID-19 increases the risk of contamination by this new coronavirus.