• Title/Summary/Keyword: model based

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Improvement Effect of Corni Fructus 30% Ethanol Extract by MIA-Induced Osteoarthritis Animal Model (MIA로 골관절염 유발된 동물모델에서 산수유(山茱萸) 30% Ethanol 추출물의 개선 효과)

  • Kim, Min Ju;Lee, Jin A;Shin, Mi-Rae;Park, Hae-Jin;Roh, Seong-Soo
    • The Korea Journal of Herbology
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    • v.35 no.1
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    • pp.35-44
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    • 2020
  • Objectives : The objective of this study was to investigate the therapeutic effect of Corni Fructus 30% ethanol extract (CFE) on the monosodium iodoacetate (MIA)-induced osteoarthritis rats. Methods : The subjects were divided into 4 groups ; Normal group (N, n=10), MIA-induced osteoarthritis control group (Con, n=10), indomethacin 5 mg/kg treated group (INDO, n=10), CFE 200 mg/kg treated group (CFE, n=10). Blood and articulation tissues were collected after two weeks of drug administration. Oxidative stress was analyzed with reactive oxygen species (ROS), peroxynitrite (ONOO-). And the Nuclear factor erythroid-2 (Nrf2), heme oxygenase-1 (HO-1), superoxide dismutase (SOD), catalase, glutathione peroxidase-1/2 (GPx-1/2), Nuclear Factor Kappa B p65 (NF-κBp65), cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), tumor necrosis factor-alpha (TNFα), interleukin-6 (IL-6), Interleukin 1β (IL-1β), matrix metalloproteinase-1 (MMP-1), and tissue inhibitor of metalloproteinases-1 (TIMP-1) were investigated by western blot. Results : The administration of CFE showed a significant reduction of changes in relative hind paw weight distribution. Reactive oxygen species (ROS) and peroxy nitrite (ONOO-) levels of articulation tissues were significantly decreased in CFE compared to the control group. Western blot measurements of Nrf2, HO-1, SOD, catalase, GPx-1/2 showed that the CFE group was increased compared to the Con group. And western blot measurements of NF-κBp65, COX-2, iNOS, TNFα, IL-6, IL-1β showed that the CFE group was reduced compared to the Con group. Also CFE group decreased MMP-1 and increased TIMP-1. Conclusion : Based on the above results, it can be seen that osteoarthritis is improved when Corni Fructus 30% ethanol extract treated.

A study on changes in water cycle characteristics of university campus catchment: focusing on potential evapotranspiration improvement in Mt. Gwanak catchment (대학 캠퍼스 유역의 물순환 특성 변화에 관한 연구: 관악산 유역 잠재증발산량 개선을 중심으로)

  • Kim, Hyeonju;Kim, Young-Oh
    • Journal of Korea Water Resources Association
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    • v.55 no.12
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    • pp.1077-1089
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    • 2022
  • With the construction of Seoul National University (SNU), the Mt. Gwanak watershed has undergone some urbanization. As with other campus catchments, data related to the water cycle is extremely limited. Therefore, this study began by collecting hydrological and meteorological data using Atmos-41, a complex meteorological observation instrument. The observation results of Atmos-41 were validated by analyzing the statistical characteristics and confidence intervals based on the monthly variability of data from the Korea Meteorological Administration. Results of the previous research were used to validate the simulated surface runoff and infiltration using the Storm Water Management Model (SWMM). The potential evapotranspiration (PET) simulated by the SWMM was rectified by comparing it to the Atmos-41 observation data. Multiple regression analysis was employed to adjust for the fluctuations in precipitation, relative humidity, and wind speed because the calculated SWMM PET tends to be underestimated during periods of low temperatures. R2 increased from 0.54 to 0.80 when compared to the Atmos-41 PET. The rate of change in the water cycle as a consequence of the SNU's construction resulted in a 15.7% increase in surface runoff, a 14.2% decrease in infiltration rate, and a 1.6% decrease in evaporation.

Improvement of Transfer Alignment Performance for Airborne EOTS (항공용 전자광학추적장비의 전달정렬 성능 개선)

  • Kim, Minsoo;Lee, Dogeun;Jeong, Chiun;Jeong, Jihee
    • Journal of Aerospace System Engineering
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    • v.16 no.4
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    • pp.60-67
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    • 2022
  • An Electro-Optical Tracking System (EOTS) is an electric optical system with EO/IR cameras, laser sensors, and an IMU. The EOTS calculates coordinates of targets, using attitude and acceleration measured by the IMU. In particular for an armed aircraft, the performance of the weapon system depends on how quickly and accurately it acquires the target coordinates. The IMU should be operated after alignment is complete, to meet the coordinate accuracy required by the weapon system so the initial stabilization time of the IMU should be reduced, by quickly measuring the attitude and acceleration. Alignment is the process of determining the initial attitude by resolving the attitude error of the IMU, and the IMU of mission equipment such as an airborne EOTS, uses velocity matching based on the velocity from GPS/INS for aircraft navigation. In this paper, a method is presented to improve the transfer alignment performance of the airborne EOTS, by maneuvering aircraft and the mission equipment. First, the performance factor of the alignment was identified, as a heading error through the velocity matching model and simulation results. Then acceleration maneuvers and attitude changes were necessary, to correct the error. As a result of flight tests applied to an EOTS on a OOO aircraft system, the transfer alignment performance was improved as the duration time was decreased, by more than five times when the aircraft accelerated by more than 0.2g and the EOTS was moving until 6.7deg/s.

Application Method of Regular Expressions and Suffixes to improve the Accuracy of Automatic Domain Identification of Public Data (공공데이터의 도메인 자동 판별 정확도 향상을 위한 정규표현식 및 접미사 적용 방법)

  • Kim, Seok-Kyoun;Lee, Kwanwoo
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.22 no.4
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    • pp.81-86
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    • 2022
  • In this work, we propose a method for automatically determining the domain of columns of file data structured by csv format. New data can be generated through convergence between data and data, and the consistency of the joined columns must be maintained in order for these new data to become an important resource. One of the methods for measuring data quality is a domain-based quality diagnosis method. Domain is the broadest indicator that defines the nature of each column, so a method of automatically determining it is necessary. Although previous studies mainly studied domain automatic discrimination of relational databases, this study developed a model that can automate domains using the characteristics of file data. In order to specialize in the domain discrimination of file data, the data were simplified and patterned using a regular expression, and the contents of the data header corresponding to the column name were analyzed, and the suffix used was used as a derived variable. When derivatives of regular expressions and suffixes were added, the result of automatically determining the domain with an accuracy of 95% greater than the existing method of 87% was derived. This study is expected to reduce the quality measurement period and number of people by presenting an automation methodology to the quality diagnosis of public data.

A Study on the Residential Satisfaction of Single Youth Households Tenants (청년 1인가구 임차인의 주거만족도에 관한 연구: 부산·경남지역을 중심으로)

  • Kwon, Jeongpyo;Kang, Jeonggyu
    • Land and Housing Review
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    • v.13 no.2
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    • pp.65-79
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    • 2022
  • To suggest implications of future housing problems, this study investigates which characteristics affect the housing satisfaction of young single households. Using the survey data, we perform the multiple regression and decision tree models based on the SPSS Statistics 25.0. Our empirical results show several key features. First, housing characteristics and intention to continue single households had a positive (+) effect on housing satisfaction, in the order of natural, housing, physical characteristics, and intention to continue single households. Second, housing characteristics and intention to marry in the future had a positive (+) effect on housing satisfaction in the order of natural, housing, and physical characteristics. Third, housing characteristics and intention to increase household members in the future had a positive (+) effect on housing satisfaction, in the order of natural, housing, and physical characteristics satisfaction. Finally, the results of the decision tree model show that the natural characteristics were over 3.4, and housing satisfaction was the highest in the case of Jeonse. The results of this study provide three implications for policymakers. First, improving the residential environment of young single households is important. Second, providing customized housing for young single households could enhance the housing satisfaction of young people. Finally, housing provision needs to be carried out with suitable space for the lifestyle of young single households.

Upstream Risks in Domestic Battery Raw Material Supply Chain and Countermeasures in the Mineral Resource Exploration Sector in Korea (국내 배터리원료광종 공급망 업스트림 리스크와 광물자원탐사부문에서의 대응방안)

  • Oh, Il-Hwan;Heo, Chul-Ho;Kim, Seong-Yong
    • Economic and Environmental Geology
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    • v.55 no.4
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    • pp.399-406
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    • 2022
  • In line with the megatrend of 2050 carbon neutrality, the amount of critical minerals used in clean-energy technology is expected to increase fourfold and sixfold, respectively, according to the Paris Agreement-based scenario as well as the 2050 carbon-neutrality scenario. And, in the case of Korea, in terms of the battery supply chain used for secondary batteries, the midstream that manufactures battery materials and battery cell packs shows strength, but the upstream that provides and processes raw materials is experiencing difficulties. The Korea Institute of Geoscience and Mineral Resources has established a strategy to secure lithium, nickel, and cobalt and is conducting surveys to respond to the upstream risk of these types of battery raw materials. In the case of lithium, exploration has been carried out in Uljin, Gyeongsangbuk-do since 2020, and by the end of 2021, the survey area was selected for precision exploration by synthesizing all exploration data and building a 3D model. Potential resources will be assessed in 2022. In the case of nickel, the prospective site will be selected by the end of 2022 through a preliminary survey targeting 10 nickel sulfide deposits that have been prospected in the past. In the case of cobalt, Boguk cobalt is known only in South Korea, but there is only a record that cobalt was produced as a minor constituent of hydrothermal deposit. According to the literature, a cobalt ore body was found in the contact area between serpentinite and granite, and a protocol for cobalt exploration in Korea will be established.

A Latent Profile Analysis of Stress Coping Strategies among Korean Adults at the Early Stage of the Coronavirus Pandemic(COVID-19) and Verification of Influencing Factors (코로나 팬데믹 초기 한국인의 스트레스 대처 양상에 따른 잠재계층 분류와 영향요인 검증)

  • Nam, Seulki;Lee, Dong Hun
    • Korean Journal of Culture and Social Issue
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    • v.28 no.3
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    • pp.483-512
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    • 2022
  • This study examined the patterns of coping strategies among Koreans during the early stage of the COVID-19 pandemic, explored the influence of demographic information (gender, age, economic level, household type), along with the unusual experiences due to COVID-19 (fear, stress of COVID, constraints of routine, income risk) on the classification of subclasses, and analyzed the latent profile differences in psychological wellbeing (life satisfaction, depression, and anxiety). An online survey was conducted among Korean Adults(n=600) between April 13, 2020 and 21, when WHO declared COVID-19 a global pandemic and Daegu as well as Gyeongsangbuk-do was nominated as a special disaster zone. First, Latent Profile Analysis (LPA) was used to identify subclasses of coping strategies and results suggested that the 4-class model had the best fit. Second, Class memberships were predicted by gender, age, economic level, as well as fear, stress, constraints of routine, and income risk, among the unusual experiences due to COVID-19. Finally, there are differences in psychological wellbeing among latent profiles. 'High level of adaptive coping group 3' showed the highest level of life satisfaction, 'Adaptive-maladaptive coping group 4' showed the highest level of depression, anxiety. Implications and suggestions are discussed based on the study results.

A Comparative Analysis of Introducing Addition and Subtraction in the Korean, Singaporean, American, and Japanese Elementary Textbooks (한국, 싱가포르, 미국, 일본의 초등학교 교과서에 제시된 덧셈과 뺄셈 도입에 대한 비교분석)

  • Pang, JeongSuk;Kim, Leena;Kim, SoHyeon
    • Communications of Mathematical Education
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    • v.36 no.2
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    • pp.229-252
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    • 2022
  • This study analyzed the introduction of addition and subtraction, including the composition and decomposition of numbers in the Korean, Singaporean, American, and Japanese elementary mathematics textbooks. The analytic foci of this study included visual models and their connections with the given problem contexts, the introduction of addition/subtraction or addition/subtraction sentences and their connections with the visual models, and additional activities for students to develop a relational understanding of the equal sign. The results of the analysis demonstrated diverse connections, mainly because the problem contexts, visual models, and the introduction of addition/subtraction or addition/subtraction sentences were implemented differently for each textbook. There were differences among the textbooks in what order of problem contexts were presented. Regarding the use of visual models, two textbooks tended to use one model consistently, whereas the other textbooks used various models depending on the problem contexts. There were subtle but significant differences in introducing addition/subtraction or addition/subtraction sentences. For a relational understanding of the equal sign, all textbooks included activities emphasizing that both sides of the equal sign are equal. Based on the results of this study, this paper closes with several implications related to the problem contexts to introduce addition/subtraction and addition/subtraction sentences as well as the use of visual models, which can serve as a basis for a new unit for the subsequent textbook.

Solar and Interplanetary Observations and Models in Korea (국내 우주환경 자료 보유 현황: 태양·행성간 공간)

  • Oh, Suyeon;Lee, Jin-Yi;Division of Solar and Space Environment of KSSS,
    • Journal of Space Technology and Applications
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    • v.1 no.2
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    • pp.160-177
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    • 2021
  • The Solar and Space Environment Division of the Korean Space Science Society investigated the use and possession of ground and satellite observations and models of solar and planetary data operated by domestic research institutes and universities. Based on the findings, we would like to introduce observational instruments, data, and models in solar and interplanetary fields in this paper to improve understanding and use of each data and explore opportunities for interdisciplinary research. The ground and satellite observations, which require a lot of investment, were mainly held by research institutes (National Meteorological Satellite Center, Polar Research Institute, Korean Space Weather, Korea Astronomy and Space Science Institute and KAIST Satellite Research Institute), and model development was overwhelmingly carried out at Kyung Hee University. In solar and interplanetary fields, we introduce Fast Imaging Solar Spectrograph (FISS), neutron monitors, and the analysis models [for the Solar Dynamics Observatory/Atmospheric Imaging Assembly (SDO/AIA) and Hinode/X-Ray Telescope (XRT) observations] in nonequilibrium ionization state as representatives. Survey on solar and interplanetary fields can be downloaded from the website of the Korean Space Science Society (http://ksss.or.kr/). The paper makes know the importance of long-term and continuous management of space science-related materials, and hopes to contribute to enhancing the status of domestic space science data by utilizing locally produced data by various personnel participating in space science research.

A basic study for explosion pressure prediction of hydrogen fuel vehicle hydrogen tanks in underground parking lot (지하주차장 수소연료차 수소탱크 폭발 압력 예측을 위한 기초 연구)

  • Lee, Ho-Hyung;Kim, Hyo-Gyu;Yoo, Ji-Oh;Lee, Hu-Yeong;Kwon, Oh-Seung
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.23 no.6
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    • pp.605-612
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    • 2021
  • Amid growing global damage due to abnormal weather caused by global warming, the introduction of eco-friendly cars is accelerating to reduce greenhouse gas emissions from internal combustion engines. Accordingly, many studies are being conducted in each country to prepare for the explosion of hydrogen fuel in semi-closed spaces such as tunnels and underground parking lots to ensure the safety of hydrogen-electric vehicles. As a result of predicting the explosion pressure of the hydrogen tank using the equivalent TNT model, it was found to be about 1.12 times and 2.30 times higher at a height of 1.5 meters, respectively, based on the case of 52 liters of hydrogen capacity. A review of the impact on the human body and buildings by converting the predicted maximum explosive pressure into the amount of impact predicted that all predicted values would result in lung damage or severe partial destruction. The predicted degree of damage was applied only by converting the amount of impact caused by the explosion, and considering the additional damage caused by the explosion, it is believed that the actual damage will increase further and safety and disaster prevention measures should be taken.