• Journal of Korea Water Resources Association
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• v.37 no.12
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• pp.1065-1074
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• 2004

This study aims at the introduction of new catchment shape descriptor, developed by Moussa(2003), based on equivalent ellipse and the assessment of its hydrologic applicability. Two descriptors a+b and a+b+${\varepsilon}OM$were correlated to the lag time and those were applied to the estimation of representative values of Nash model parameters. They are applied in order to examine the practicality to 3 catchments in Korea, catchments in Korea, respectively, i.e. Pyeongchanggang catchment in Han river, Bocheongcheon catchment in Geum river and Wicheon catchment in Nakdong river. As a result both of two descriptors show higher correlations to the lag lime than classical geomorphologic factors and hereby Moussa's suggestion(2003) is confirmed. For the sake of simplicity the former is recommended. Also representative IUHs derived from this study show consistent basin response characteristics. It is desirable to conduct further more case studies on many other basins.

• Journal of the Society of Naval Architects of Korea
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• v.33 no.2
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• pp.13-29
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• 1996

This paper presents calculated results of the free-surface flow around a Series 60($C_B=0.6$) model. Three-dimensional Navier-Sotkes equations are solved and Baldwin-Lomax algebraic turbulence model is adopted to simulate the high Reynolds-number flow. To reduce computational efforts, velocity components near the wall are extrapolated with a the solved by using the Implicit Approximate Factorization method[2]. The successive-over-relaxation method is used for solving pressure-Poisson equation when obtaining the pressure field projecting the divergence-free velocity field. To simulate the free-surface flows more precisely, the numerical scheme solving the equation for the kinematic boundary condition is very important. In this paper, there numerical schemes are employed and the results are compared with the available experimental data.

• Fire Science and Engineering
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• v.23 no.5
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• pp.143-152
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• 2009

The numerical analyses for each single simplified shaft with three type openings were carried out by using computational fluid dynamics model for the calculation of the pressure difference and the location of the neutral plane and the visualization of stack effect. As the height of shaft heighten, the pressure difference of stack effect is much deviated against the theoretical value. For the Type A models shorter than 30 m height of shaft and the Type B models longer than 30m, the simulation results for the location of the neutral plane are well agreed to the theoretical values with 5% less deviations just after the beginning of simulation (t = 10s). For the Type B models longer than 30m with multiple openings, therefore, it is possible to calculate the location of the neutral plane by using a CFD model. The phenomenon of the air flow of stack effect can be easily understood with the visualization of stack effect.

• Korean Journal of Agricultural and Forest Meteorology
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• v.6 no.3
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• pp.149-163
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• 2004

Evapotranspiration (ET) is a critical component of the hydrologic cycle which influences economic activities as well as the natural ecosystem. While there have been numerous studies on ET estimation for homogeneous areas using point measurements of meteorological variables, monitoring of spatial ET has not been possible at landscape - or watershed - scales. We propose a site-specific application of the land surface model, which is enabled by spatially interpolated input data at the desired resolution. Gyunggi Province of South Korea was divided into a regular grid of 10 million cells with 30m spacing and hourly temperature, humidity, wind, precipitation and solar irradiance were estimated for each grid cell by spatial interpolation of synoptic weather data. Topoclimatology models were used to accommodate effects of topography in a spatial interpolation procedure, including cold air drainage on nocturnal temperature and solar irradiance on daytime temperature. Satellite remote sensing data were used to classify the vegetation type of each grid cell, and corresponding spatial attributes including soil texture, canopy structure, and phenological features were identified. All data were fed into a standalone version of SiB2(Simple Biosphere Model 2) to simulate latent heat flux at each grid cell. A computer program was written for data management in the cell - based SiB2 operation such as extracting input data for SiB2 from grid matrices and recombining the output data back to the grid format. ET estimates at selected grid cells were validated against the actual measurement of latent heat fluxes by eddy covariance measurement. We applied this system to obtain the spatial ET of the study area on a continuous basis for the 2001-2003 period. The results showed a strong feasibility of using spatial - data driven land surface models for operational monitoring of regional ET.

• Journal of the Korean Association of Geographic Information Studies
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• v.6 no.3
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• pp.129-138
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• 2003

A new methodology for selecting spatially variable model control parameter values through consideration of inference models within a Hydroinformatic system has been developed to overcome problems associated with determination of spatially variable control parameter values for both ungauged and gauged catchment. The adopted Hydroinformatic tools for determination of control parameter values were a GIS(Arc/Info) to handle spatial and non-spatial attribute information, the SWMM(stormwater management model) to simulate catchment response to hydrologic events, and lastly, L_BFGS_B(a limited memory quasi-Newton algorithm) to assist in the calibration process. As a result, high accuracy of control parameter estimation was obtained by considering the spatial variations of the control parameters based on landuse characteristics. Also, considerable time and effort necessary for estimating a large number of control parameters were reduced from the new calibration approach.

• Journal of Veterinary Science
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• v.24 no.3
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• pp.23.1-23.16
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• 2023

Background: Irritable bowel syndrome (IBS) is a functional bowel disorder (FBD). Objectives: To assess the therapeutic effects of paeoniflorin (PF) on IBS in rats. Method: Sixty male Sprague-Dawley rats were randomly divided into normal, model, positive drug, low-dose PF, medium-dose PF and high-dose PF groups (n = 10). After gavage for 2 consecutive weeks, the effect of PF on abdominal pain symptoms was assessed based on the abdominal withdrawal reflex (AWR) score, fecal water content and pathological changes in colon tissues. D-lactate, interleukin-1β (IL-1β), transforming growth factor-β (TGF-β) and tumor necrosis factor-α (TNF-α) were detected by enzyme-linked immunosorbent assay, and phosphorylated nuclear factor kappa B (p-NF-κB) p65 was detected by Western blotting. The abundance and diversity changes of intestinal flora were explored using 16S ribosomal RNA sequencing. Result: In PF groups, the mucosal morphology of colon tissues was intact, and the glands were arranged neatly and structured clearly, without obvious inflammatory cell infiltration. Compared with the model group, PF groups had significantly elevated pain threshold, and mRNA and protein levels of zonula occludens-1 (ZO-1) and occludin, decreased AWR score at 20 mmHg pressure, fecal water content, mRNA levels of IL-1β, TGF-β, and TNF-α, protein level of p-NF-κB p65 and level of serum D-lactate, and reduced levels of serum IL-1β, TGF-β, and TNF-α (p < 0.05, p < 0.01). PF groups had higher abundance of Lactobacillus, Akkermansia, Alistipes, and Bacteroides, but lower abundance of Desulfovibrio, Parasutterella, and Enterococcus than those of the model group. Conclusions: PF exerts therapeutic effects on IBS in rats probably by regulating the intestinal flora, and then up-regulating the expressions of ZO-1 and occludin in colon tissue while down-regulating the levels of IL-1β, TGF-β, TNF-α, D-lactate and p-NF-κB p65.

• Asian-Australasian Journal of Animal Sciences
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• v.25 no.4
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• pp.531-540
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• 2012

Pigs from four sire lines were allocated to a series of low energy (LE, 3.15 to 3.21 Mcal ME/kg) corn-soybean meal-based diets with 16% wheat midds or high energy diets (HE, 3.41 to 3.45 Mcal ME/kg) with 4.5 to 4.95% choice white grease. All diets contained 6% DDGS. The HE and LE diets of each of the four phases were formulated to have equal lysine:Mcal ME ratios. Barrows (N = 2,178) and gilts (N = 2,274) were fed either high energy (HE) or low energy (LE) diets from 27 kg BW to target BWs of 118, 127, 131.5 and 140.6 kg. Carcass primal and subprimal cut weights were collected. The cut weights and carcass measurements were fitted to allometric functions (Y = A $CW^B$) of carcass weight. The significance of diet, sex or sire line with A and B was evaluated by linearizing the equations by log to log transformation. The effect of diet on A and B did not interact with sex or sire line. Thus, the final model was cut weight = (1+$b_D$(Diet)) A($CW^B$) where Diet = -0.5 for the LE and 0.5 for HE diets and A and B are sire line-sex specific parameters. Diet had no affect on loin, Boston butt, picnic, baby back rib, or sparerib weights (p>0.10, $b_D$ = -0.003, -0.0029, 0.0002, 0.0047, -0.0025, respectively). Diet affected ham weight (bD = -0.0046, p = 0.01), belly weight (bD = 0.0188, p = 0.001) three-muscle ham weight ($b_D$ = -0.014, p = 0.001), boneless loin weight (bD = -0.010, p = 0.001), tenderloin weight ($b_D$ = -0.023, p = 0.001), sirloin weight ($b_D$ = -0.009, p = 0.034), and fat-free lean mass ($b_D$ = -0.0145, p = 0.001). Overall, feeding the LE diets had little impact on primal cut weight except to decrease belly weight. Feeding LE diets increased the weight of lean trimmed cuts by 1 to 2 percent at the same carcass weight.

• Biomedical Science Letters
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• v.18 no.3
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• pp.210-217
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• 2012

Oncolytic viral vectors have shown good candidates for cancer treatment but have many limitations. To improve the therapeutic potential of oncolytic vaccinia virus, we developed a recombinant vaccinia virus expressing the 4-1BBL co-stimulatory molecule or CCL21. 4-1BBL and CCL21 expression was identified by FACS analysis and immunoblotting. rV-4-1BBL vaccination shows significant tumor regression compared to rV-LacZ, but rV-CCL21 shows rapid tumor growth compared to rV-LacZ in the poorly immunogenic B16 murine melanoma model. 4-1BBL expression resulted in the increase of the number of CD8+ T cells and especially the increase of effector (CD62L-CD44+) CD8+ T cells. These data suggest 4-1BBL may be the potential target for enhancement of tumor immunotherapy.

• The Transactions of the Korean Institute of Electrical Engineers B
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• v.48 no.3
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• pp.104-109
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• 1999

In order to design and predict the performance of the harmonic side drive motor, it is necessary to analyze the torque generated by the structure. In this paper, an analytical model is proposed for design. Conformal mapping is used to model the capacitance and torque of the motor as a function of the rotor angular position with two-dimensional approximation. Then the result of conformal mapping analysis is verified with F.E.M result.

• Journal of the Korean Institute of Telematics and Electronics B
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• v.33B no.3
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• pp.96-108
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• 1996

In this paper, we propose an object-oriented coding method in low bit-rate channels using block-based motion vectors and residual image compensation. First, we use a 2-stage algorithm for estimating motion parameters. In the first stage, coarse motion parameters are estimated by fitting block-based motion vectors and in the second stage, the estimated motion parametes are refined by the gradient method using an image reconstructed by motion vectors detected in the first stage. Local error of a 6-parameter model is compensted by blockwise motion parameter correction using residual image. Finally, model failure (MF) region is reconstructed by a fractal mapping method. Computer simulation resutls show that the proposed method gives better performance than the conventional ones in terms of th epeak signal to noise ratio (PSNR) and compression ratio (CR).