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Control of swine respiratory disease using egg yolk antibodies III. Immunopropbylactic effect of IgY in mouse model (난황항체를 이용한 돼지 호흡기 질병 방제에 관한 연구 III. 마우스에서의 방어 효과)

  • Shin, Na-Ri;Kim, Jong-man;Yoo, Han-Sang
    • Korean Journal of Veterinary Research
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    • v.41 no.3
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    • pp.351-356
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    • 2001
  • As an attempt to control respiratory disease in swine, specific immunologloblin Ys(IgYs) against bacterial pathogens of the diseases were produced and specificity of the IgYs was analysed with Western blot in the previous studies. In this studies, the immunoprotective effects of produced IgY were evaluated in the mice. Mice were challenged with minimal lethal doses of P multocida 3A and 4D, B bronchiseptica and A pleuropneumoniae serotype 2 after intraperitoneal administration of IgY and the protectivity by IgY was dose-dependent at the concentration of 100, 200 and 400 mg/ml. These results suggested that IgY could be a potential immunoprophylactic candidates against those pathogens in swine and apply and effective source of passive immunity for other disease in animals.

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Study on the Assessment Method of Urban Traffic Noise Using the 3D Noise mapping in Cheongju city (소음지도를 이용한 도시 교통 소음 평가방법에 관한 연구)

  • Ko, J.H.;Park, S.J.;Chang, S.I.;Lim, J.S.;Lee, B.C.
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2006.11a
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    • pp.48-53
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    • 2006
  • Noise mapping is performed in the city of Cheongju which has 626,614 inhabitants on a $153.41km^2$ area. This city has 71,387 buildings and 969,274m roads. Many database sets like information of roads, topography and buildings are required for making the noise map of large area. These database sets are provided by the various departments of the regional administration in Cheongju city. Using the given database sets, 3-dimensional model of topography and buildings are made to consider the multi-reflections and diffractions. A predicted noise level is compared with measured noise level of the road traffic noise. As the tool of management and decision of urban noise policy, noise map is combined into the map of land use to make the conflict noise map. This conflict noise map is useful to assess the present urban noise and to make the better life in complicated urban life.

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Prediction of Backscattering Strength and Volume (동물플랑크톤에 의한 후방산란강도 및 체적복반사음의 예측)

  • 나정열
    • Proceedings of the Acoustical Society of Korea Conference
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    • 1992.06a
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    • pp.127-130
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    • 1992
  • 한국 근해에서 능동소나 (active sonar) 사용시 사용되는 environmental parameters 가운데 하나인 volume reverberation(REv)을 산출하기 위하여 플랑크톤에 의한 후방산란 강도(backscattering strength)에 대한 연구를 하였다. 이를 위하여 수산진흥원 자료(80-89년)중 부유생물조사표에서 후방산란 강도가 다른 종에 비하여 큰 copepoda의 개체수를 평균한 후, 수심별 개체수를 계산하여 수심별, 주파수별(10, 50kHz), 계절별(2월, 8월) 후방산란 강도와 multipath eigenray model을 이용하여 REv를 산출하였다. 예로 사용한 동남해역(zone:S3), 서해중부해역(zone:W3)에서 주파수별 REv는 일반적인 형태인 포기에는 고주파가 높고, 1.5초 이후에는 저주파가 높게 나타났다. 그러나 여름이 겨울보다 플랑크톤 개체수가 많아 후방산란 강도가 크지만(2-5dB), REv는 겨울이 더 크게 나타났다. 이러한 이유는 SVP profile에 의한 pressure 계산결과, 여름에는 ray가 down-ward이고 겨울에는 duct를 형성하여 ray가 거의 direct로 진행하므로 transmission loss가 여름이 크기 때문이다. 또한 ray tracing결과 여름철에는 ray crossing이 많아 겨울에 비하여 fluctuation이 심하게 나타나는 현상을 보이고 있다. 두 지역 이외에도 한국근해의 정확한 REv을 예측하기 위해서는 플랑크톤의 정확한 측정과, 이론적인 수치와 비교할 수 있는 실측치를 얻는 것이 필요하다고 볼 수 있다.

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An Analysis and Evaluation of the Effectiveness of Decision Making During the Review of Scientifically Constructed Project Proposals

  • Abdykerova, G.Zh;Bukayeva, A.D.
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.3 no.2
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    • pp.31-44
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    • 2008
  • A selection technique for innovative projects on the beginning stage has been presented in this article. It can be applied in projects assessment in HEI, enterprises, development institutes, etc. It is rather difficult to assess the project quality on the beginning stage of R&D due to the uncertainty in the technical and economic indices but the new development analysis on this stage is of a great interest. By innovative project quality as a management object we will mean those characteristics relating to the results capacity of the projects and its realization process to satisfy the requirements to the innovative products competitiveness and their innovative attractiveness for investors. The most important question in the innovative projects management is the determination of its quality level under modern conditions. The aim of the research is to analyze and evaluate the decision making during the project management process. The objectives and hypotheses are assessment of an innovative project with the application of McKinsey's model is better to realizes by 3 stages: a) selection of optimal criteria; b) determination of weighing coefficients; c) projects positioning in a matrix.

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Performance Assessment of a Lithium-Polymer Battery for HEV Utilizing Pack-Level Battery Hardware-in-the-Loop-Simulation System

  • Han, Sekyung;Lim, Jawhwan
    • Journal of Electrical Engineering and Technology
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    • v.8 no.6
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    • pp.1431-1438
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    • 2013
  • A pack-level battery hardware-in-the-loop simulation (B-HILS) platform is implemented. It consists of dynamic vehicle models using PSAT and multiple control interfaces including real-time 3D driving and GPS mode. In real-time 3D driving mode, user can drive a virtual vehicle using actual drive equipment such as steering wheel and accelerator to generate the cycle profile of the battery. In GPS mode, actual road traffic and terrain effects can be simulated using GPS data while the trajectory is displayed on Google map. In the latter part of the paper, several performance tests of an actual lithium-polymer battery pack are carried out utilizing the developed system. All experiments are conducted as parts of actual development process of a commercial battery pack adopting 2nd generation Prius as a target vehicle model. Through the experiments, the low temperature performance and fuel efficiency of the battery are quantitatively investigated in comparison with the original nickel-metal hydride (NiMH) pack of the Prius.

Inhibition of Experimental Lung Inflammation and Bronchitis by Phytoformula Containing Broussonetia papyrifera and Lonicera japonica

  • Ko, Hyun-Jeong;Jin, Jeong-Ho;Kwon, Oh-Song;Kim, Jong-Taek;Son, Kun-Ho;Kim, Hyun-Pyo
    • Biomolecules & Therapeutics
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    • v.19 no.3
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    • pp.324-330
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    • 2011
  • Broussonetia papyrifera and Lonicera japonica have long been used in the treatment of inflammatory disorders, especially respiratory inflammation, in Chinese medicine. Previously, phytoformula (BL) containing B. papyrifera and L. japonica was found to exert strong anti-inflammatory activity in vitro and in vivo. In this study, the effects of BL on lung inflammation including bronchitis were examined in vitro and in vivo. BL (10-100 ${\mu}g$/ml) inhibited nitric oxide (NO) production of lipopolysaccharide (LPS)-treated alveolar macrophages, MH-S cells, primarily by down-regulating inducible NO synthase. BL also inhibited production of the proinflammatory cytokines, TNF-${\alpha}$ and IL-6. Against an animal model of pleural cavity inflammation, BL (200-400 mg/kg) significantly inhibited 5 h and 24 h carrageenan-induced pleurisy in rats when administered orally. Additionally, BL inhibited experimental bronchitis induced by intratracheal instillation of LPS to rats. Taken together, these results indicate that BL may be effective for the treatment of human lung inflammation as well as bronchitis.

Simulation of Capacitively Graded Bushing for Very Fast Transients Generated in a GIS during Switching Operations

  • Rao, M.Mohana;Rao, T. Prasad;Ram, S.S. Tulasi;Singh, B.P.
    • Journal of Electrical Engineering and Technology
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    • v.3 no.1
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    • pp.36-42
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    • 2008
  • In a gas insulated substation (GIS), Very Fast Transient Over-voltages (VFTOs) are generated due to switching operations and ground faults. These fast transients are associated with high frequency components of the order of a few hundreds of MHz. These transients may cause internal faults i.e., layer-to-layer faults or minor faults in a capacitively graded bushing, which is one of the important pieces of terminal equipment for GIS. In the present study, the PSPICE model has been developed to calculate the voltage distribution across the layers of 420kV graded bushing for high frequency pulses of rise time 1 to 50ns, which simulate the VFTO. For this simulation, an equivalent electrical network of bushing with different equivalent layers has been considered. The effect of different equivalent layers modeling circuits on the non-uniform voltage factor has been analysed. The influence of copper strip inductance on voltage distribution across layers has also been analysed for various rise times of high frequency transients. Finally, the leakage current of the bushing is calculated for evaluating the bushing condition under these transients.

Design of Digital Circuit Structure Based on Evolutionary Algorithm Method

  • Chong, K.H.;Aris, I.B.;Bashi, S.M.;Koh, S.P.
    • Journal of Electrical Engineering and Technology
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    • v.3 no.1
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    • pp.43-51
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    • 2008
  • Evolutionary Algorithms (EAs) cover all the applications involving the use of Evolutionary Computation in electronic system design. It is largely applied to complex optimization problems. EAs introduce a new idea for automatic design of electronic systems; instead of imagine model, ions, and conventional techniques, it uses search algorithm to design a circuit. In this paper, a method for automatic optimization of the digital circuit design method has been introduced. This method is based on randomized search techniques mimicking natural genetic evolution. The proposed method is an iterative procedure that consists of a constant-size population of individuals, each one encoding a possible solution in a given problem space. The structure of the circuit is encoded into a one-dimensional genotype as represented by a finite string of bits. A number of bit strings is used to represent the wires connection between the level and 7 types of possible logic gates; XOR, XNOR, NAND, NOR, AND, OR, NOT 1, and NOT 2. The structure of gates are arranged in an $m{\times}n$ matrix form in which m is the number of input variables.

MATHEMATICAL MODELLING AND ITS SIMULATION OF A QUASI-STATIC THERMOELASTIC PROBLEM IN A SEMI-INFINITE HOLLOW CIRCULAR DISK DUE TO INTERNAL HEAT GENERATION

  • Gaikwad, Kishor R.
    • Journal of the Korean Society for Industrial and Applied Mathematics
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    • v.19 no.1
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    • pp.69-81
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    • 2015
  • The present paper deals with the determination of temperature, displacement and thermal stresses in a semi-infinite hollow circular disk due to internal heat generation within it. Initially the disk is kept at arbitrary temperature F(r, z). For times t > 0 heat is generated within the circular disk at a rate of g(r, z, t) $Btu/hr.ft^3$. The heat flux is applied on the inner circular boundary (r = a) and the outer circular boundary (r = b). Also, the lower surface (z = 0) is kept at temperature $Q_3(r,t)$ and the upper surface ($Z={\infty}$) is kept at zero temperature. Hollow circular disk extends in the z-direction from z = 0 to infinity. The governing heat conduction equation has been solved by using finite Hankel transform and the generalized finite Fourier transform. As a special case mathematical model is constructed for different metallic disk have been considered. The results are obtained in series form in terms of Bessel's functions. These have been computed numerically and illustrated graphically.

Sloshing characteristics of an annular cylindrical tuned liquid damper for spar-type floating offshore wind turbine

  • Jeon, S.H.;Seo, M.W.;Cho, Y.U.;Park, W.G.;Jeong, W.B.
    • Structural Engineering and Mechanics
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    • v.47 no.3
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    • pp.331-343
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    • 2013
  • The natural sloshing frequencies of annular cylindrical TLD are parametrically investigated by experiment, aiming at the exploration of its successful use for suppressing the structural vibration of spar-type floating wind turbine subject to multidirectional wind, wave and current excitations. Five prototypes of annular cylindrical TLD are defined according to the inner and outer radii of acryl container, and eight different liquid fill heights are experimented for each TLD prototype. The apparent masses near the first and second natural sloshing frequencies are parametrically investigated by measuring the apparent mass of interior liquid sloshing to the acceleration excitation. It is observed from the parametric experiments that the first natural sloshing frequency shows the remarkable change with respect to the liquid fill height for each TLD model with different container dimensions. On the other hand, the second natural sloshing frequency is not sensitive to the liquid fill height but to the gap size, for all the TLD models, convincing that the annular cylindrical sloshing damper can effectively suppress the wave- and wind-induced tilting motion of the spar-type floating wind turbine.