• Title/Summary/Keyword: mobile application development

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Development and validation of an LC-MS/MS method for determination of compound K in human plasma and clinical application

  • Kim, Jung Soo;Kim, Yunjeong;Han, Song-Hee;Jeon, Ji-Young;Hwang, Minho;Im, Yong-Jin;Kim, Jung Hyun;Lee, Sun Young;Chae, Soo-Wan;Kim, Min-Gul
    • Journal of Ginseng Research
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    • v.37 no.1
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    • pp.135-141
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    • 2013
  • A rapid, sensitive and selective analytical method was developed and validated for the determination of compound K, a major intestinal bacterial metabolite of ginsenosides in human plasma. Liquid-liquid extraction was used for sample preparation and analysis, followed by liquid chromatography tandem spectrometric analysis and an electrospray-ionization interface. Compound K was analyzed on a Phenomenex Luna C18 column ($100{\times}2.00$ mm, 3 ${\mu}m$) with the mobile phase run isocratically with 10 mM ammonium acetate-methanol-acetonitrile (5:47.5:47.5, v/v/v) at a flow rate of 0.5 mL/min. The method was validated for accuracy (relative error <12.63%), precision (coefficient of variation <9.14%), linearity, and recovery. The assay was linear over the entire range of calibration standards i.e., a concentration range of 1 ng/mL to 1,000 ng/mL ($r^2$ >0.9968). The recoveries of compound K after liquid-liquid extraction at 1, 2, 400, and 800 ng/mL were $106.00{\pm}0.08%$, $103.50{\pm}0.19%$, $111.45{\pm}5.21%$, and $89.62{\pm}34.46%$ for intra-day and $85.40{\pm}0.08%$, $94.50{\pm}0.09%$, $112.50{\pm}5.21%$, and $95.87{\pm}34.46%$ for inter-day, respectively. The lower limit of quantification of the analytical method of compound K was 1 ng/mL in human plasma. The developed method was successfully applied to a pharmacokinetic study of compound K after oral administration in ten of healthy human subjects.

Design and Implementation of Interactive Game based on Embedded System (내장형 시스템 기반 체험형 게임의 설계 및 구현)

  • Lee, Woosik;Jung, Hoejung;Heo, Hojin;Kim, Namgi
    • Journal of Internet Computing and Services
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    • v.18 no.4
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    • pp.43-50
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    • 2017
  • Embedded System includes touch, GPS, motion, and acceleration sensor, and can communicate with neighbor devices using wireless communication. Because Arduino with embedded system provides good environment for development and application, developers, engineers, designers, as well as artists, students have a great interest. They utilize Arduino in the robot, home appliances, fashion, culture and so on. In this paper, we design and implement a game using Arduino with embedded system which recognizes the human movement by moving away from one-dimensional game of the existing touch method. Implemented embedded system game measures gyro-sensor to recognize human movement and detects the attack success of the opponent by using touch sensor. Moreover, health of the game player is updated in the real time through the android phone-based database. In this paper, implemented embedded system-based game provides GUI screen of android phone. It is possible to select watching mode and competition mode. Also, it has low energy consumption and easy to expand because it send and receive data packet through recent Bluetooth communication.

Development of a Raspberry Pi-based Banknote Recognition System for the Visually Impaired (시각장애인을 위한 라즈베리 파이 기반 지폐 인식기 개발)

  • Lee, Jiwan;Ahn, Jihoo;Lee, Ki Yong
    • The Journal of Society for e-Business Studies
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    • v.23 no.2
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    • pp.21-31
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    • 2018
  • Korean banknotes are similar in size, and their braille tend to worn out as they get old. These characteristics of Korean banknotes make the blind people, who mainly rely on the braille, even harder to distinguish the banknotes. Not only that, this can even lead to economic loss. There are already existing systems for recognizing the banknotes, but they don't support Korean banknotes. Furthermore, because they are developed as a mobile application, it is not easy for the blind people to use the system. Therefore, in this paper, we develop a Raspberry Pi-based banknote recognition system that not only recognizes the Korean banknotes but also are easily accessible by the blind people. Our system starts recognition with a very simple action of the user, and the blind people can hear the recognition results by sound. In order to choose the best feature extraction algorithm that directly affects the performance of the system, we compare the performance of SIFT, SURF, and ORB, which are representative feature extraction algorithms at present, in real environments. Through experiments in various real environments, we adopted SIFT to implement our system, which showed the highest accuracy of 95%.

Development and Application of Real-time Measurement System of Silt Loading for Estimating the Emission Factor of Resuspended Dust from Paved Road (포장도로 재비산먼지 배출계수 산정을 위한 silt loading의 실시간 측정시스템 개발과 적용)

  • Han, Se-Hyun;Won, Kyung-Ho;Jang, Ki-Won;Son, Young-Min;Kim, Jeong-Suk;Hong, Ji-Hyung;Jung, Yong-Won
    • Journal of Korean Society for Atmospheric Environment
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    • v.23 no.5
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    • pp.596-611
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    • 2007
  • Resuspended dust from paved roads in Seoul and Incheon metropolitan areas is regarded as one of the major $PM_{10}$ sources in these areas, according to the recent emission estimates using the emission factors compiled in AP-42. It is well known that the AP-42 model for estimating $PM_{10}$ emissions from paved roads requires information on silt loadings of particular paved roads. The conventional AP-42 method (vacuum swept method) for road silt sampling, however, is expensive, time consuming, and dangerous. These drawbacks led us to develop a Mobile Dust Monitoring System (MDMS) capable of doing real time measurements of silt loading of paved roads, thereby we could get higher resolution silt loading data both in terms of time and space without too much human efforts and danger. In this study, for the real-time measurement of silt loading of paved roads, the principle used in the TRAKER method of U.S. Desert Research Institute was employed and the entire sampling systems including data acquisition system were designed for theses purpose and mounted on a SUV. The correlation between the silt loading measured by vacuum swept method and the speed corrected ${\Delta}Dust$ was derived for the vehicle-based silt loading measurements, and then the variations of silt loading on paved roads were surveyed using the MDMS in test routes of Seoul and Incheon. From the results of real-time measurements, temporal and spatial variations of silt loading data together with the existence of hot spots were observed for paved roads in Seoul and Incheon. The result of this study will be employed to estimate fugitive dust emissions from paved roads.

Establishment of content criteria of marker compounds through the monitoring of Achyranthis Radix collected from Korea and China (한국 및 중국 지역에서 수집된 우슬의 모니터링을 통한 지표성분의 함량기준 설정)

  • Kim, Dae-Hyun;Kim, Sang-Hyuk;Jang, Yu-Seon;Shin, Min-Chul;Chu, Van Men;Lee, Young-Keun;Woo, Mi-Hee;Kang, Jong-Seong
    • Analytical Science and Technology
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    • v.25 no.4
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    • pp.250-256
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    • 2012
  • Two marker compounds of Achyranthis Radix, ecdysterone and inokosterone, were analyzed by HPLC on an ODS column ($250{\times}4.6$ mm, 5 ${\mu}m$) with a mobile phase of 15% acetonitrile containing 0.08% formic acid at a flow rate of 1.0 mL/min and a detection wavelength of UV 254 nm. The method was validated by ICH guideline and applied to the monitoring of marker compounds in 93 samples of Achyranthis Radix collected at various areas in Korea and China. The new content criteria of ecdysterone and inokosterone, established using linear regression method were 0.033% and 0.020%, respectively. When the new content criteria were applied to the quality control test of commercial Achyranthis Radix, 95.4% of total samples including 100% of Korean and 92.6% of Chinese samples were passed the test. Application of new content criteria could protect the Korean products and decrease the distribution of Chinese products with lower quality.

A Measurement System for Color Environment-based Human Body Reaction (색채 환경 기반의 인체 반응 정보 측정 시스템)

  • Kim, Ji-Eon;Jeong, Chang-Won;Joo, Su-Chong
    • Journal of Internet Computing and Services
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    • v.17 no.2
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    • pp.59-65
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    • 2016
  • The result of analyzing the cognitive reaction due to the color environment has been applied to various filed especially in medical field. Moreover, the study about the identification of patient's condition and examination the brain activity by collecting the bio-signal based on the color environment is being actively conducted. Even though, there were a variety of experiments by convention the color environment using a light or LED color, it still has a problem that affects the psychological information. Therefore, our proposed system using a HMD (Head Mounting display) to provide a completed color environment condition. This system uses the BMS(Biomedical System) to collect the biometric information which responds to the specific color condition and the human body response information can be measured by the development the Memory and Attention test on Mobile phone. The collection of Biometric information includes electro cardiogram(ECG), respiration, oxygen saturation (Sp02), Bio-impedance, blood pressure will store in the database. In addition, we can verify the result of the human body reaction in the color environment by Memory and Attention application. By utilizing the reaction of the human body information that is collected thought the proposed system, we can analyze the correlation between the physiological information and the color environment. And we also expect that this system can apply to the medical diagnosis and treatment. For future work, we will expand the system for prediction and treatment of Alzheimer disease by analyzing the visualization data through the proposed system. We will also do evaluation on the effectiveness of the system for using in the rehabilitation program.

Interactive Statistics Laboratory using R and Sage (R을 활용한 '대화형 통계학 입문 실습실' 개발과 활용)

  • Lee, Sang-Gu;Lee, Geung-Hee;Choi, Yong-Seok;Lee, Jae Hwa;Lee, Jenny Jyoung
    • Communications of Mathematical Education
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    • v.29 no.4
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    • pp.573-588
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    • 2015
  • In this paper, we introduce development process and application of a simple and effective model of a statistics laboratory using open source software R, one of leading language and environment for statistical computing and graphics. This model consists of HTML files, including Sage cells, video lectures and enough internet resources. Users do not have to install statistical softwares to run their code. Clicking 'evaluate' button in the web page displays the result that is calculated through cloud-computing environment. Hence, with any type of mobile equipment and internet, learners can freely practice statistical concepts and theorems via various examples with sample R (or Sage) codes which were given, while instructors can easily design and modify it for his/her lectures, only gathering many existing resources and editing HTML file. This will be a resonable model of laboratory for studying statistics. This model with bunch of provided materials will reduce the time and effort needed for R-beginners to be acquainted with and understand R language and also stimulate beginners' interest in statistics. We introduce this interactive statistical laboratory as an useful model for beginners to learn basic statistical concepts and R.

Development of RFID terminal for the Blind to Voice Guide Pharmaceutical E-pedigree (시각장애인을 위한 RFID 의약품 음성안내 단말기 개발)

  • Kang, Joon-Hee;Ahn, Sung-Soo;Kim, Jin-Young
    • 전자공학회논문지 IE
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    • v.47 no.3
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    • pp.19-25
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    • 2010
  • We developed a RFID terminal to voice guide the blind who have difficulties in reaching out to the pharmaceutical information. In this work, we used RFID technology to instruct the pharmaceutical information to the blind. The voice guidance reader was made to read the RFID tag attached to the drugs and announced the pharmaceutical information matching to the tag specific ID. We had the reader to obtain the pharmaceutical information from the ezDrug site operated by Korea Food & Drug Association. The voice guidance reader was fabricated as necklace type for the easy carry, and we added mp3 player as dual uses. ARM series Cortex M3 chip was used for the reader's core chip and low power MFRC523 chipset of NXP was used to construct RFID circuit. MFRC523 chip uses low power to meet the mobile application. We used VS1003B MP3 Decoder IC to make the voice generation circuit and CC2500 chipset for the wireless communication to the pharmaceutical information server. We also developed the system that can support ISO 14443A type and ISO 14443B type so that the system can be used to extend to various RFID protocols. Utilization of this system can conveniently convey the pharmaceutical information to the blind and reduce the drug abuse.

Development and Application of a Turtle Ship Model Based on Physical Computing Platform for Students of Industrial Specialized High School (공업계 특성화고 학생을 위한 피지컬 컴퓨팅 플랫폼 기반의 모형 거북선 개발 및 적용)

  • Kim, Won-Woong;Choi, Jun-Seop
    • 대한공업교육학회지
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    • v.41 no.2
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    • pp.89-118
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    • 2016
  • In this study, the model of Turtle Ship, which is evaluated as one of the world's first ironclad ship in battle as well as the traditional scientific and technological heritage in Korea, was combined with the Physical Computing Platform(Arduino and App Inventor) that enables students to learn the basic concepts of IT in an easy and fun way. Thus, this study contrived the Physical Computing Platform-based Turtle Ship model which will make the students of Industrial Specialized High School develop the technological literacy and humanities-based knowledge through flexible education out of stereotype and single subject as well as enhance the potential of creative convergence education. The following is a summary of the main results obtained through this study: First, Arduino-based Main-controller design and making is helpful to learn of the hardware and software knowledge about EEC(Electron Electronics Control) and to confirm the basic characteristics and performance of interaction of Arduino and actuators. Second, The fundamental Instructional environments of abilities such as implementing EEC systems, thinking logically, and problem-solving skills were provided by designing of pattern diagram, designing an actuator circuit and making, the creation of sketches as technical programming and developing of mobile app. Thirdly, This is physical computing platform based Turtle ship model that will enable students to bring up their technological literacy and interest in the cultural heritage.

Development of Human Resource Management Program for Protected Horticulture (시설재배 인력관리 프로그램 개발)

  • Myung, Dong-Ju;Shin, Gyung-Ho;Lee, Jeong-Hyun;Kim, Eun Ji;Lee, Beom-Seon
    • Journal of Bio-Environment Control
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    • v.30 no.4
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    • pp.359-366
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    • 2021
  • This study aimed to develop and verify the smart human resource management (HRM) program in a large scale greenhouse. HRM program delivers detailed work orders to workers and gathers work results by mobile phone application. Greenhouse managers can monitor the workload, work speed, quality of employee by HRM program and can analyse performance easily. Greenhouse Managers can set the work speed including 'twisting', 'trimming' and 'harvesting' in a greenhouse. It makes planning work schedule and assigns resources to each specific job easier. Therefore, the manager can arrange the number of employees to promote work performance and also easy to estimate the labor shortage. Greenhouse managers can evaluate the adequacy of the number of employees through job performance analysis by period and adjusts the supply/demand ratio of regular and non-regular employees. The HRM program can improve work efficiency by announcing the real-time work performance of all employees on a monitor screen to induce competition among workers and re-educate unripe employees who accomplish behind average to improving work skills.