• 정신신체의학
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• 제29권2호
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• pp.199-206
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• 2021

Objectives : This study aimed to compare the characteristics of suicide attempts among Korean patients with mixed and non-mixed depression. Methods : Patients who visited the emergency room due to a suicide attempt and participated in the Korean Cohort for the Model Predicting a Suicide and Suicide-related Behavior study were included. Using the Montgomery-Asberg Depression Rating Scale (MADRS) and Young Mania Rating Scale (YMRS), 111 patients were classified into the mixed depression (n=46) and non-mixed depression groups (n=65). The Koukopoulos Mixed Depression Rating Scale (KMDRS) score was calculated using the MADRS and YMRS scores. Suicide attempt characteristics were evaluated using the Columbia Suicidal Severity Rating Scale (C-SSRS) and Suicide Intent Scale (SIS). Results : In the mixed depression group, the reason item among the ideation intensity score of the C-SSRS was higher, and the deterrent item score was lower. Scores on the timing and suicide note items of the SIS were higher, and scores for overt communication items were lower in the mixed depression group. The KMDRS score was positively correlated with the C-SSRS ideation intensity and total SIS score. After adjusting for additional variables, the KMDRS scores had a significant effect on the C-SSRS ideation intensity and total SIS scores. Conclusions : The mixed depression group showed a difference in the intensity of suicidal ideation and suicidal intention compared to those in the non-mixed depression group. The overall suicidal ideation intensity and suicidal intention increased according to the degree of mixed depression.

• Clinical Psychopharmacology and Neuroscience
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• 제16권4호
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• pp.376-382
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• 2018

We reviewed clinical studies investigating the pharmacological treatment of major depressive episodes (MDEs) with mixed features diagnosed according to the dimensional criteria (more than two or three [hypo]manic symptoms+principle depressive symptoms). We systematically reviewed published randomized controlled trials on the pharmacological treatment of MDEs with mixed features associated with mood disorders, including major depressive disorder (MDD) and bipolar disorder (BD). We searched the PubMed, Cochrane Library, and ClinicalTrials.gov databases through December 2017 with the following key word combinations linked with the word OR: (a) mixed or mixed state, mixed features, DMX, mixed depression; (b) depressive, major depressive, MDE, MDD, bipolar, bipolar depression; and (c) antidepressant, antipsychotic, mood stabilizer, anticonvulsant, treatment, medication, algorithm, guideline, pharmacological. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We found few randomized trials on pharmacological treatments for MDEs with mixed features. Of the 36 articles assessed for eligibility, 11 investigated MDEs with mixed features in mood disorders: six assessed the efficacy of antipsychotic drugs (lurasidone and ziprasidone) in the acute phase of MDD with mixed features, although four of these were post hoc analyses based on large randomized controlled trials. Four studies compared antipsychotic drugs (olanzapine, lurasidone, and ziprasidone) with placebo, and one study assessed the efficacy of combination therapy (olanzapine+fluoxetine) in the acute phase of BD with mixed features. Pharmacological treatments for MDEs with mixed features have focused on antipsychotics, although evidence of their efficacy is lacking. Additional well-designed clinical trials are needed.

• 한국재료학회지
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• 제23권11호
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• pp.625-630
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• 2013

In this study, intermediate-mixed powders were prepared by loading zirconia powders initially in a ball-mill jar and loading alumina powders afterward; the initial-mixed powders were produced by loading zirconia and alumina powders together in the ball-mill jar. The effect of such differences in mixing method on the mechanical properties was investigated. In intermediate-mixed powders, the volume fraction of large particles slightly increased and, simultaneously, zirconia particles formed agglomerates that, due to early ball-mill loading of the zirconia powders only, were more dispersed than were the initial-mixed powders. For the intermediate-mixed powders, zirconia agglomerates were destroyed more quickly than were initial-mixed powders, so the number of dispersed zirconia particles rose and the inhibitory effect of densification due to the addition of a second phase was more obvious. In the microstructure of intermediate-mixed powders, zirconia grains were homogeneously dispersed and grain growth by coalescence was found to occur with increasing sintering temperature. For the initial-mixed powders, large zirconia grains formed by localized early-densification on the inside contacts of some zirconia agglomerates were observed in the early stages of sintering. The intermediate-mixed powders had slightly lower hardness values as a whole but higher fracture toughness compared to that of the initial-mixed powders.

• 한국주거학회논문집
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• 제21권4호
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• pp.11-22
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• 2010

In the urban area where rapid suburbanization trend continues, the role of mixed use building is controversial. It is argued that the mixed use building is an effective tool to recover residential function of urban core(urban regeneration). It is also argued that the building is a cause of serious urban problems, such as congestion, public service shortages. The fundamental purpose of this study is to examine the role of mixed use building in terms of urban growth management in Seoul. For this purpose, data of mixed use building from 1981 to 2007 are collected and analysed. The results show that most of mixed use buildings are located in either sub-centers or population losing areas, rather than traditional urban core. Therefore, it is hard to accept that the two controversial arguments. The mixed use building noncore areas in most cases. However, it dose help to increase population inflow in non-core areas. it is difficult to accept the public service assertion which states that super-high rise mixed use building causes public service congestion, because the building is built in population losing or demand decreasing area. Based on these findings this study suggests some policy alternatives such as urban service boundary or concurrency program to management urban growth.

• 교육시설
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• 제16권1호
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• pp.69-77
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• 2009

This study, as one of the specific suggestions to satisfy the social needs of life long education and to overcome the limitations of the supply of regional facilities, presents plans for the possibility of the mixed-use of educational facilities and regional facilities as the ultimate objective. By focusing on the space composition of the mixed-use facility to execute the roles of the educational establishment actively and efficiently, the purpose is to present the mixed-use methodology in architectural plan on which functions to combine and by how much, when the mixed-use plan of educational facilities. The investigation objects was the 27 elementary schools in Seoul which have undergone mixed-use of educational facilities work as at August, 2007. And each educational facility was classified mixed-use functions and analyzed for the composition form of functions and the characteristics by functions. And for mixed-use facility, form types were derived from the relationship with the school buildings through the analysis on characteristics, strengths and weaknesses of each types were presented by factor-by-factor plan directions of mixed-use facility.

• 교육시설 논문지
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• 제21권4호
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• pp.3-10
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• 2014

The opportunity, provided for a direction planning mixed-use facilities for secondary schoo, is the purpose of this paper. Mixed-use facilities are an important issue in school building as it seeks to revive the facilities for local residents in school zone. The latest works of mixed-use facilities in secondary school, however, which are evaluated as well reflected the patterns of education and local community, are still deficient in that communicational elements in secondary school are inadequate. The cases of this paper, which are grown up as an educational building with mixed-use facilities opened to the local residents, are suitable to offer the design method for the future secondary school with mixed-use facilities. This paper reviews an assessment of its success in mixed-use facilities for secondary school as a public building for both of local residents and students and concludes with the establishment of design method for the future school; extraction of the factors contributing to development of mixed-use facilities in school area and proposal of design method; implementation of renewal of mixed-use facilities including educational program and spaces for the creation of identity.

• 한국멀티미디어학회논문지
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• 제24권1호
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• pp.155-165
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• 2021

With the continuous development and progress of science and technology, the field of mixed reality applications has involved scientific research, medicine, entertainment, education, information dissemination, and people's daily lives; This paper will focus on the application of mixed reality in the field of education and teaching, relying on the characteristics of mixed reality technology. This article will use the combination of mixed reality and smart glasses to fully consider the characteristics of photography darkroom teaching, design and produce a mixed reality photography darkroom teaching software, and explore the feasibility of the application of mixed reality in teaching. This paper will use literature research methods, practical research methods, and survey methods as the main methods of research topics to determine the importance, feasibility, and necessity of the relevant theories studied in this paper. The application of mixed reality technology in photography darkroom teaching can not only solve many problems in the existing darkroom teaching methods, but also develop and expand students' Independent learning ability. It is concluded from this that mixed reality teaching software has the feasibility of sustainable development, which brings particular application value to the development and research of other education and art discipline software.

• 대한수학회지
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• 제55권3호
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• pp.605-622
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• 2018

The original mixed multiplicity theory considered the class of mixed multiplicities concerning the terms of highest total degree in the Hilbert polynomial. This paper defines a broader class of mixed multiplicities that concern the maximal terms in this polynomial, and gives many results, which are not only general but also more natural than many results in the original mixed multiplicity theory.

• 한국통계학회:학술대회논문집
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• 한국통계학회 2005년도 춘계 학술발표회 논문집
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• pp.1-6
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• 2005

SAS의 PROC MIXED는 ANOVA 추정량보다 더 다양한 잔차최대우도추정법 또는 최대우도추정법으로 모수들을 추론할 수 있다. 혼합모형에 속하는 불균형중첩오차구조를 갖는 선형회귀모형에서 랜덤효과에 해당되는 그룹간의 분산과 고정효과에 해당되는 회귀계수들에 대한 신뢰구간을 구하기 위하여 대표본인 경우와 소표본인 경우에 대하여 PROC MIXED를 사용한다. 시뮬레이션을 실행한 결과, 대표본인 경우에는 모수들의 신뢰구간을 구하기 위하여 PROC MIXED를 활용할 수 있지만, 소표본인 경우에는 PROC MIXED를 사용할 경우, 그룹간 분산과 회귀계수 가운데 하나인 절편항에 대한 신뢰구간은 시뮬레이터된 신뢰계수가 명시한 신뢰계수를 지키지 못하는 것을 보인다.

• 대한용접접합학회:학술대회논문집
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• 대한용접접합학회 2007년 추계학술발표대회 개요집
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• pp.8-10
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• 2007

In recent years, hydrogen-oxygen mixed gas generated by electrically dissociating water has been proposed as alternative cutting fuel. The mixed gas consists of a hydrogen-oxygen mixed gas in the mixture ratio of 2:1. And gas has some merits as cutting quality and speed compared with existing gas cutting process. Because main source of mixed gas is water, mixed gas is environmental-friendly clean fuel. The purpose of the present paper is to investigate cutting characteristics and optimum cutting parameters of mixed gas, The effect of cutting parameter on the cutting characteristics of mixed gas is also investigated as compared to existing gas cutting process.