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Evaluation of MR Based Respiratory Motion Correction Technique in Liver PET/MRI Study (Liver PET/MRI 검사 시 MR 기반 호흡 움직임 보정 방법의 유용성 평가)

  • Do, Yong Ho;Lee, Hong Jae;Kim, Jin Eui;Noh, Gyeong Woon
    • The Korean Journal of Nuclear Medicine Technology
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    • v.22 no.1
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    • pp.15-22
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    • 2018
  • Purpose Respiratory motion during PET/MRI acquisition may result in image blurring and error in measurement for volume and quantification of lesion. The aim of this study was to evaluate changes of quantitative accuracy, tumor size and image quality by applying MR based respiratory motion correction technique (MBRMCT) using integrated PET/MR scanner. Materials and Methods Data of 30 patients (aged $62.5{\pm}10.2y$) underwent $^{18}F-FDG$ liver PET/MR (Biograph mMR 3.0T, Siemens) study were collected. PET listmode data for 7 minutes was simultaneously acquired with maximum average gate (MAG), minimum time gate (MTG) and non gate (NG) T1 weighted MR images. Gated PET reconstruction was performed using mu-maps generated from MAG and MTG by setting 35% of efficiency window. Maximum SUV ($SUV_{max}$), peak SUV ($SUV_{peak}$), tumor size and full width at half maximum (FWHM) in the z-axis direction of MAG, MTG and NG PET images were evaluated. Results Compared to NG, mean $SUV_{max}$ and $SUV_{peak}$ were increased in MAG 13.15%(p<0.0001), 8.66%(p<0.0001), MTG 13.27%(p<0.0001), 8.80%(p<0.0001) and mean tumor size and FWHM were decreased in MAG 14.47%(p<0.0001), 15.49%(p=0.0004), MTG 14.89%(p<0.0001), 15.79%(p=0.0003) respectively. Mean $SUV_{max}$ and $SUV_{peak}$ of MTG were increased by 0.07%(p=0.8802), 0.13%(p=0.7766). Mean tumor size and FWHM of MTG were decreased by 0.49%(p=0.2786), 0.36%(p=0.2488) compared to MAG. There was no statistically significant difference between MAG and MTG which increase total scan time for about 7 and 2 minutes. Conclusion SUV, accuracy of tumor size and spatial resolution were improved in both of MAG and MTG by applying MBRMCT without installing additional hardware in liver PET/MR study. More accurate information can be provided with the increase of 2 minutes scan time if applying MTG of MBRMCT to various abdominal PET/MR studies affected by respiratory motion.

In vitro study of Polymerization shrinkage-strain kinetics of dental resin cements (치과용 레진 시멘트의 중합 수축률 특성에 관한 연구)

  • Kim, Tae-Hoon;Yang, Jae-Ho;Lee, Jai-Bong;Han, Jung-Suk;Kim, Sung-Hun
    • The Journal of Korean Academy of Prosthodontics
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    • v.48 no.1
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    • pp.55-60
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    • 2010
  • Purpose: The shrinkage of dental resin cement may cause several clinical problems such as distortion that may jeopardize the accurate fit to the prepared tooth and internal stress within the restorations. It is important to know the polymerization shrinkage-strain of dental resin cement to reduce clinical complications. The purpose of this study was to investigate the polymerization shrinkage-strain kinetics of six commercially available dental resin cements. Material and methods: Three self-cure resin cements (Fujicem, Superbond, M-bond) and three dual-cure resin cements (Maxcem, Panavia-F, Variolink II) were investigated. Time dependent polymerization shrinkage-strain kinetics of the materials were measured by the Bonded-disk method as a function of time at $23^{\circ}C$, with values particularly noted at 1, 5, 10, 30, 60, 120 min after mixing. Five recordings were taken for each materials. The data were analyzed with one-way ANOVA and Scheffe post hoc test at the significance level of 0.05. Results: Polymerization shrinkage-strain values were 3.72%, 4.19%, 4.13%, 2.44%, 7.57%, 2.90% for Fujicem, Maxcem, M bond, Panavia F, Superbond, Variolink II, respectively at 120 minutes after the start of mixing. Panavia F exhibited maximum polymerization shrinkage-strain values, but Superbond showed minimum polymerization shrinkage-strain values among the investigated materials (P < .05). There was no significant differences of shrinkage-strain value between Maxcem and M bond at 120 minutes after the start of mixing (P > .05). Most shrinkage of the resin cement materials investigated occurred in the first 30 minutes after the start of mixing. Conclusion: The onset of polymerization shrinkage of self-cure resin cements was slower than that of dual-cure resin cements after mixing, but the net shrinkage strain values of self-cure resin cements was higher than that of dual-cure resin cements at 120 minutes after mixing. Most shrinkage of the dental resin cements occurred in the first 30 minutes after mixing.

Sex-Discrimination of Silkworm Pupa, Bombyx mori with Image Analyzer (화상처리장치에 의한 번데기 암수판별의 효과)

  • ;Tohru Nakada
    • Journal of Sericultural and Entomological Science
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    • v.35 no.2
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    • pp.105-113
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    • 1993
  • To produce F1 hybrid of silkworm sex discrimination has to be followed at the pupal stage by sexual organ. However it requires a lot of labour and may bring about a wrong classification. In these regards, this study has been implemented to find out an effective measure for the pupal sex discrimination by use of variation of cocoon weight and image analysis of cocoon. As a result, it was found that in case of the pupal weight the percentage of a wrong classification fell on 0.3% and in case of single cocoon weight 0.4%. The discrimination rate was 99% in the weight variables of cocoon but analysis by single cocoon weight and cocoon shape variables, it was 98.7%. Efficiency of discrimination was increased by 2.7% as compared to variable of single cocoon weight. The minimum cocoon sampling size may be 15 cocoons sexual-wise.

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A PHOTOMETRIC STUDY OF THE CONTACT BINARY XZ LEONIS

  • Lee Jae-Woo;Lee Chung-Uk;Kim Chun-Hwey;Kang Young-Woon
    • Journal of The Korean Astronomical Society
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    • v.39 no.2
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    • pp.41-50
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    • 2006
  • We present the results of new multi-color CCD photometry for the contact binary XZ Leo, together with reasonable explanations for the period and light variations. Six new times of minimum light have been determined. A period study with all available timings confirms Qian's (2001) finding that the O-C residuals have varied secularly according to $dP/dt\;=\;+8.20{\times}10^{-8}\;d\;yr^{-l}$. This trend could be interpreted as a conservative mass transfer from the less massive cool secondary to the more massive hot primary in the system with a mass flow rate of about $5.37{\times}10^{-8}\;M_{\odot}\;yr^{-l}$. By simultaneous analysis of our light curves and the previously published radial-velocity data, a consistent set of light and velocity parameters for XZ Leo is obtained. The small differences between the observed and theoretical light curves are modelled by a blue third light and by a hot spot near the neck of the primary component. Our period study does not support the tertiary light but the hot region which may be formed by gas streams from the cool secondary. The solution indicates that XZ Leo is a deep contact binary with the values of q=0.343, $i=78^{\circ}.8$, ${\Delta}(T_1-T_2)=126\;K$, and f=33.6 %, differing much from those of Niarchos et al. (1994). Absolute parameters of XZ Leo are determined as follows: $M_1=1.84\;M_{\odot},\;M_2=0.63\;M_{\odot},\;R_1=1.75\;R_{\odot},\;R_2=1.10\;R_{\odot},\;L_1=7.19\;L_{\odot},\;and\;L_2=2.66\;L_{\odot}$.

Dye-Perfused Human Placenta for Simulation in a Microsurgery Laboratory for Plastic Surgeons

  • Laura C. Zambrano-Jerez;Karen D. Diaz-Santamaria;Maria A. Rodriguez-Santos;Diego F. Alarcon-Ariza;Genny L. Melendez-Florez;Monica A. Ramirez-Blanco
    • Archives of Plastic Surgery
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    • v.50 no.6
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    • pp.627-634
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    • 2023
  • In recent decades, a number of simulation models for microsurgical training have been published. The human placenta has received extensive validation in microneurosurgery and is a useful instrument to facilitate learning in microvascular repair techniques as an alternative to using live animals. This study uses a straightforward, step-by-step procedure for instructing the creation of simulators with dynamic flow to characterize the placental vascular tree and assess its relevance for plastic surgery departments. Measurements of the placental vasculature and morphological characterization of 18 placentas were made. After the model was used in a basic microsurgery training laboratory session, a survey was given to nine plastic surgery residents, two microsurgeons, and one hand surgeon. In all divisions, venous diameters were larger than arterial diameters, with minimum diameters of 0.8 and 0.6 mm, respectively. The majority of the participants considered that the model faithfully reproduces a real microsurgical scenario; the consistency of the vessels and their dissection are similar in in vivo tissue. Furthermore, all the participants considered that this model could improve their surgical technique and would propose it for microsurgical training. As some of the model's disadvantages, an abundantly thick adventitia, a thin tunica media, and higher adherence to the underlying tissue were identified. The color-perfused placenta is an excellent tool for microsurgical training in plastic surgery. It can faithfully reproduce a microsurgical scenario, offering an abundance of vasculature with varying sizes similar to tissue in vivo, enhancing technical proficiency, and lowering patient error.

A Study on Stochastic Estimation of Monthly Runoff by Multiple Regression Analysis (다중회귀분석에 의한 하천 월 유출량의 추계학적 추정에 관한 연구)

  • 김태철;정하우
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.22 no.3
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    • pp.75-87
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    • 1980
  • Most hydro]ogic phenomena are the complex and organic products of multiple causations like climatic and hydro-geological factors. A certain significant correlation on the run-off in river basin would be expected and foreseen in advance, and the effect of each these causual and associated factors (independant variables; present-month rainfall, previous-month run-off, evapotranspiration and relative humidity etc.) upon present-month run-off(dependent variable) may be determined by multiple regression analysis. Functions between independant and dependant variables should be treated repeatedly until satisfactory and optimal combination of independant variables can be obtained. Reliability of the estimated function should be tested according to the result of statistical criterion such as analysis of variance, coefficient of determination and significance-test of regression coefficients before first estimated multiple regression model in historical sequence is determined. But some error between observed and estimated run-off is still there. The error arises because the model used is an inadequate description of the system and because the data constituting the record represent only a sample from a population of monthly discharge observation, so that estimates of model parameter will be subject to sampling errors. Since this error which is a deviation from multiple regression plane cannot be explained by first estimated multiple regression equation, it can be considered as a random error governed by law of chance in nature. This unexplained variance by multiple regression equation can be solved by stochastic approach, that is, random error can be stochastically simulated by multiplying random normal variate to standard error of estimate. Finally hybrid model on estimation of monthly run-off in nonhistorical sequence can be determined by combining the determistic component of multiple regression equation and the stochastic component of random errors. Monthly run-off in Naju station in Yong-San river basin is estimated by multiple regression model and hybrid model. And some comparisons between observed and estimated run-off and between multiple regression model and already-existing estimation methods such as Gajiyama formula, tank model and Thomas-Fiering model are done. The results are as follows. (1) The optimal function to estimate monthly run-off in historical sequence is multiple linear regression equation in overall-month unit, that is; Qn=0.788Pn+0.130Qn-1-0.273En-0.1 About 85% of total variance of monthly runoff can be explained by multiple linear regression equation and its coefficient of determination (R2) is 0.843. This means we can estimate monthly runoff in historical sequence highly significantly with short data of observation by above mentioned equation. (2) The optimal function to estimate monthly runoff in nonhistorical sequence is hybrid model combined with multiple linear regression equation in overall-month unit and stochastic component, that is; Qn=0. 788Pn+0. l30Qn-1-0. 273En-0. 10+Sy.t The rest 15% of unexplained variance of monthly runoff can be explained by addition of stochastic process and a bit more reliable results of statistical characteristics of monthly runoff in non-historical sequence are derived. This estimated monthly runoff in non-historical sequence shows up the extraordinary value (maximum, minimum value) which is not appeared in the observed runoff as a random component. (3) "Frequency best fit coefficient" (R2f) of multiple linear regression equation is 0.847 which is the same value as Gaijyama's one. This implies that multiple linear regression equation and Gajiyama formula are theoretically rather reasonable functions.

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Effect of Cassava Hay and Rice Bran Oil Supplementation on Rumen Fermentation, Milk Yield and Milk Composition in Lactating Dairy Cows

  • Lunsin, R.;Wanapat, Metha;Rowlinson, P.
    • Asian-Australasian Journal of Animal Sciences
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    • v.25 no.10
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    • pp.1364-1373
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    • 2012
  • Four crossbred (75% Holstein Friesian) lactating dairy cows, with an average live weight of $418{\pm}5$ kg and $36{\pm}10$ d in milk were randomly assigned according to a $2{\times}2$ factorial arrangement in a $4{\times}4$ Latin square design to evaluate the effects of cassava hay (CH) and rice bran oil (RBO) on feed intake, nutrient digestibility, ruminal fermentation, milk yield, and milk composition. Factor A was non-supplementation or supplementation with CH in the concentrate. Factor B was supplementation with RBO at 0% or 4% in the concentrate mixture. The four dietary treatments were (T1) control (Concentrate with non-CH plus 0% RBO; C), (T2) Concentrate with CH plus 0% RBO (CH), (T3) Concentrate with non-CH plus 4% RBO (RBO), and (T4) Concentrate with CH plus 4% RBO (CHRBO). The cows were offered concentrate, at a ratio of concentrate to milk production of 1:2, and urea-lime treated rice straw was fed ad libitum. Urea-lime treated rice straw involved 2.5 g urea and 2.5 g $Ca(OH)_2$ (purchased as hydrated lime) in 100 ml water, the relevant volume of solution was sprayed onto a 100 g air-dry (91% DM) straw, and then covering the stack with a plastic sheet for a minimum of 10 d before feeding directly to animals. The CH based concentrate resulted in significantly higher roughage intake and total DM intake expressed as a percentage of BW (p<0.05). Ruminal pH, $NH_3$-N, BUN and total VFA did not differ among treatments, while RBO supplementation increased propionate, but decreased acetate concentration (p<0.05). Furthermore, the population of total ruminal bacteria was significantly lower on the RBO diet (p<0.05). In contrast, the total ruminal bacteria and cellulolytic bacteria on the CH diet were higher than on the other treatments. Supplementation with CH increased (p<0.05) F. succinogens and R. flavefaciens populations, whereas the populations of B. fibrisolvens and M. elsdenii were increased on the RBO diet. In addition, supplementation with CH and RBO had no effect on milk production and composition in dairy cows, while fatty acid composition of milk was influenced by RBO supplementation, and resulted in significantly lower (p<0.05) concentrations of both short-chain and medium-chain FA, and increased (p<0.05) the proportion of long-chain FA in milk fat, as well as significantly increased cis-9, trans-11 CLA and total CLA. In conclusion, RBO or CH exhibited specific effects on DMI, rumen fermentation, microbial population, milk yield and composition in lactating dairy cows, which were not interactions between CH and RBO in the diets. Feeding lactating dairy cows with RBO could improve fatty acid in milk fat by increasing cis-9, trans-11 CLA.

DEVELOPMENT OF SAFETY-BASED LEVEL-OF-SERVICE PARAMETERS FOR TWO-WAY STOP-CONTROLLED INTERSECTIONS (무신호 교차로의 안전 -서비스 수준 측정에 관한 연구-)

  • 이수범
    • Proceedings of the KOR-KST Conference
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    • 1996.02a
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    • pp.59-86
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    • 1996
  • Current methods for evaluating unsignalized intersections, and estimating level-of-service (LOS) is determined from efficiency-based criteria such as little or no delay to very long delays. At present, similar procedures to evaluate intersections using safety-based criteria do not exist. The improvement of sight distances at intersections is the most effective way of improving intersection safety. However, a set of procedures is necessary to account for the limitations in current methodology. Such an approach would build upon such methods, but also account for: deficiencies in the current deterministic solution for the determination of intersection sight distances; opportunity for an accident and severity of an accident; and cost-effectiveness of attaining various levels of sight distances. In this research, a model that estimates the degree of safety at two-way stop-controlled intersections is described. Only crossing maneuvers are considered in this study because accidents caused by the crossing maneuvers are the dominate type among intersection accidents. Monte Carlo methods are used to estimate the hazard at an intersection as a function of roadway features and traffic conditions. Driver`s minimum gap acceptance in the crossing vehicles and headway distribution on the major road are used in the crossing vehicles and headway distribution on the major road are used in the model to simulate the real intersectional maneuvers. Other random variables addressed in the model are: traffic speeds; preception-reaction times of both drivers in the crossing vehicles and drivers in oncoming vehicles on the major road; and vehicles on the major roads. The developed model produces the total number of conflicts per year per vehicle and total potential kinetic energy per year per vehicle dissipated during conflicts as measurements of safety at intersections. Based on the results from the developed simulation model, desirable sight distances for various speeds were determined as 350 feet, 450 feet and 550 feet for 40 mph, 50 mph and 60 mph prevailing speed on the major road, respectively. These values are seven to eight percent less than those values recommended by AASHTO. A safety based level-of-service (LOS) is also developed using the results of the simulation model. When the total number of conflicts per vehicle is less than 0.05 at an intersection, the LOS of the intersection is `A' and when the total number of conflicts per vehicle is larger than 0.25 at an intersection, the LOS is `F'. Similarly, when the total hazard per vehicle is less than 350, 000 1b-ft2/sec2, the LOS is `F'. Once evaluation of the current safety at the intersection is complete, a sensitivity analysis can be done by changing one or more input parameters. This will estimate the benefit in terms of time and budget of hazard reduction based upon improving geometric and traffic characteristics at the intersection. This method will also enable traffic engineers in local governments to generate a priority list of intersection improvement projects.

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Stability Analysis of Nonhomogeneous Slopes by Log -spiral Failure Surface (이질토층사면의 대수누선파양에 대한 안정해석)

  • Kim, Yeong-Su;Seo, In-Seok;Baek, Yeong-Sik
    • Geotechnical Engineering
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    • v.9 no.2
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    • pp.41-54
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    • 1993
  • This paper presents the two and three -dimensional stability analysis of nonhom- ogeneous, c-o soil slopes. Potential failure surface is assumed as a logspiral curve refracted in boundaries of layers. In 3-D analysis, rotational soil mass is assumed with a cylindroid central part terminated with plane ends. Seismic force is considered by sesmic intensity. The program developed in this study is compared with the program PCSTABLS. The ratio of three-dimensional minimum factor of safety to two-dimensional case is examined and factor of safety changes are showed for the ratio of cylindroid length to slope height and numbers of slice. On such bases the following conclusions may by made : (1) The program developed in this program is less conservative than the program PCSTABLS. (2) The value of F2 of this study shows the larger differences than that of PCSTABLS with increasing friction angle (3) Factors of safety computed for 3-D geometry differ considerablely from ordinary 2-D factors of safety. Since Fb/F2 exceeds unity, three -dimensional effects tend to increase the factor of safety. (4) As the ratio of three - dimensional failure width of slope height, b/H increase, the value of Fb/Ff decreases and approaches 1.0 when bye is 14. (5) In calculating the factor of safety using the developed program the number of slices is suitable with the ranges of 30-40

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BIOLOGICAL STUDIES ON THE FRESH-WATER SHRIMPS IN KOREA 2. The Ecology of Palaemon modestua (한국산 민물 새우류에 관한 생물학적 연구 2. Palaemon modestua의 생태)

  • CHUNG Kyung-Suk
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.3 no.2
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    • pp.110-116
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    • 1970
  • The fresh_water shrimp, Palaemon modestua is one of the most important types of bait f[r fishing and can be found abundantly in the Nak-Dong River. The larval development of Palaemon modestua in the laboratory was reported by Liu (1949), Kown and Uno (1968), but they didn't give any ecological features in the natural environments. Shrimps were collected from the Nak-Dong River near Pusan, once a month from July to December 1953 and from February to June 1969 respectively. The following is a summary of the results: 1. They breed from April to September, mainly in July. 2. A generation of this type of shrimps appears to be approximately one year and after breeding they die off up untill the end of October. 3. The sex ratio (female=100) is $44.2\~95.5$ (mean 78.5) and goes down during spawning seasons. 4. The minimum size of the ovigerous female is approximately 0.5 gram in body weight, 29mm in body length and 7mm in carapace length. 5. Most shrimps of $31\~41mm$ In body length lay eggs. 6. The relationship between the boby length (X) and the number of eggs (Y) is: $$Y=0.0000203937X^{3.5668}$$ 7. The relationship between the body length (X) and the body weight (Y) is: $$Y=0.099801X^{2.85407}$$ in female. $$Y=0.004198X^{3.40614}$$ in Male. 8. The relationship between the carapace length (X) and the body weight (Y) is: $$Y=5.56008X^{2.25503}$$ in female. $$Y=5.09541X^{2.28875}$$ in male. 9. The relationship between the carapace length (X) and the body length (Y) is: Y= 5.07540+3.36057X in female. Y=4.90514+3.47791X in male.

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