• Molecules and Cells
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• 제28권4호
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• pp.383-388
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• 2009

The dehydration responsive element binding protein 2C (DREB2C) is a dehydration responsive element/C-repeat (DRE/CRT)-motif binding transcription factor that induced by mild heat stress. Previous experiments established that overexpression of DREB2C cDNA driven by the cauliflower mosaic virus 35S promoter (35S:DREB2C) resulted in increased heat tolerance in Arabidopsis. We first analyzed the proteomic profiles in wild-type and 35S:DREB2C plants at a normal temperature ($22^{\circ}C$), but could not detect any differences between the proteomes of wild-type and 35S: DREB2C plants. The transcript level of DREB2C in 35S: DREB2C plants after treatment with mild heat stress was increased more than two times compared with expression in 35S:DREB2C plants under unstressed condition. A proteomic approach was used to decipher the molecular mechanisms underlying thermotolerance in 35S:DREB2C Arabidopsis plants. Eleven protein spots were identified as being differentially regulated in 35S:DREB2C plants. Moreover, in silico motif analysis showed that peptidyl-prolyl isomerase ROC4, glutathione transferase 8, pyridoxal biosynthesis protein PDX1, and elongation factor Tu contained one or more DRE/CRT motifs. To our knowledge, this study is the first to identify possible targets of DREB2C transcription factors at the protein level. The proteomic results were in agreement with transcriptional data.

• Restorative Dentistry and Endodontics
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• 제20권1호
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• pp.235-249
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• 1995

This study was designed to identify the lymphocytes present and to examine the relation between lymphocytes population and clinical symptoms of the pulps clinically diagnosed as normal and irreversible pulpitis. We recorded the history and severity of the pain and performed several clinical tests, before extirpation of vital, irreversibly inflamed pulps in routine endodontic treatment. Then the teeth were divided into two groups. Five teeth, categorized in acute symptom group, had severe spontaneous pain, particularly at night and were extremely sensitive to cold and heat. The other 15 teeth with history of mild to moderate pain and with or without cold or heat responses were categorized as chronic symptom group. Inflamed pulps were also classified into 8 minor groups by presence or absence of signs or symptoms related to the involved teeth, including the presence of pain on percussion, pain on heat and cold stimuli and the periodontal pocket depth. All extirpated pulps were immediately immersed in ultra low-temperature freezer($-74^{\circ}C$), and they were sectioned $6{\mu}m$ in thickness. Specimens were stained using three-stage indirect immunoperoxidase techniques(DAKO, LSAB kit) and monoclonal antibodies for detecting the presence of T lymphocytes(T), B lymphocytes(B) and helper(T4) and suppressor(T8) lymphocytes. Following results were obtained; 1. All the examined normal and inflamed pull) tissues had positive staining for T lymphocytes and T helper and T suppressor cells. But B cells were observed only in inflamed pulp. 2. Statistically more T and B cells were observed in acute symptom group as compared with chronic symptom group(p<0.05). 3. Cell ratio of BIT in acute symptom group were significantly higher than that of chronic symptom group(p<0.05). 4. Only B cells were significantly increased in the percussion positive group than the number of B cells in percussion negative group(p<0.05). 5. No differences were observed in the number of different cell types among other minor groups.

• 한국식품과학회지
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• 제16권1호
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• pp.120-126
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• 1984

본 연구에서는 대두단백질의 가열에 의한 변성이 L. acidophilus의 생육에 미치는 영향과 SPI-Yogurt에 첨가되는 여러 가지 영양분이 L. acidophilus의 생육에 미치는 영향을 관찰하였고 제조된 요구르트의 flavor를 조사하였다. SOY milk를 SPI(단백질 4.2%)와 여러 가지 당(糖) 및 발육촉진물질로 제조하였고, 준비된 SOY milk 100ml를 적절히 가열살균후 24시간 배양된 유산균 2.5ml를 접종하고 $37^{\circ}C$의 항온기에서 24시간 배양하였다. 유산균 생육의 정도는 생균수, 산도, pH로 판단하였다. SPI로부터 요구르트제조시 가열의 정도가 극심하지 않으면 유산균의 생육에는 큰 지장이 없었으며, 적정(適正) 살균 조건은 $95^{\circ}C$, 20분정도였다. 본 실험에서 사용된 당(糖) 가운데 포도당과 유당이 유산균의 생육과 산(酸) 생성에 현저한 효과를 보였으며, 그 적정(適正) 농도는 각각 3% 정도였다. 첨가된 발육촉진물질 가운데 Yeast extract가 유산균에 의한 산의 생성을 촉진시켰으며 그 적정(適正) 농도는 0.5% 정도였다. 대두단백질의 농도는 유산균의 생육에는 큰 영향이 없었으나 생산된 요구르트의 점도에 현저한 영향을 미쳤다.

• 한국산림과학회지
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• 제104권1호
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• pp.84-89
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• 2015

'대보' 박피밤의 갈변 및 품질에 화학물질(ascorbic acid, citric acid, calcium chloride: 1% 용액)과 물리적(진공포장, $50^{\circ}C$ 증류수) 처리가 미치는 영향을 조사하였다. 박피밤 색도의 L값은 모든 처리구에서 저장기간이 경과함에 따라 감소하는 경향을 나타낸 반면, ${\Delta}E$값은 점차 증가하는 경향을 보였다. 일반포장 처리구가 급격히 색 변화가 일어나는데 비해 화학 및 물리적 처리구는 완만한 변화를 보였다. 특히 calcium chloride 처리구는 색 변화가 거의 일어나지 않았다. 관능적 품질평가 결과, 상품성은 일반포장 처리구가 10일간 유지되었던 반면 화학 및 물리적 처리구들은 35일간 상품성이 유지되었다. 따라서 '대보' 박피밤의 화학 및 물리적 처리는 갈변을 억제시킴으로써 박피밤의 관능적 품질유지에 효과적이였고, 특히 1% calcium chloride 침지 후 진공포장하는 것이 박피밤의 품질유지와 갈변 억제에 가장 효과적인 것으로 판단되었다.

• 대한기계학회논문집
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• 제12권3호
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• pp.489-496
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• 1988

본 연구에서는 오스템퍼링 처리된 구상흑연주철의 오스템퍼링 처리온도와 유 지시간을 변화시킨 후 대기중의 건조미끄름마찰실험을 하여 내마멸특성을 검토하는 것 을 목적으로 하였다.

• Journal of Welding and Joining
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• 제2권1호
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• pp.41-48
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• 1984

Recrystallization technique was applied to analyze plastic strain at the notch tip of coarse grain HAZ in mild steel (SB 41) and high strength steel (SA 588). The notch tip of specimen was deformed by three point bending. Accumulated displacement (Crack Opening Displacement ${delta}t$) by the monotonic and cyclic loading under room temperature and hot strain embrittlement temperature ($250^{\circ}C$) was 0~1.0mm. Recrystallization heat treatment conditions were $650^{circ}C{ imes}3hr$ for SB 41 and $700^{circ}C{ imes}3hr$ for SA 588. The experimental results obtained were as follows ; 1) Distribution of the effective plastic strain at plastic zone was appeared by the function of crack opening displacement, and plastic zone or the effective plastic strain increased with crack opening displacement. 2) Plastic strain at notch tip of HAZ due to accumulated hot strain calculated as follows. .epsilon. over bar $_{p}$ = .epsilon. over bar $_{cr}$ (x/ $R_{x}$ ) $^{m}$ (m=0.25) 3) Work hardending ratio of notch tip for hot strain was linearly increased with .epsilon. over bar $_{max}$ and dependent upon the material types.s.

• 대한한방소아과학회지
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• 제37권3호
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• pp.17-34
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• 2023

Objectives Few studies to date reviewed herbal medicines prescribed to pediatric patients with coronavirus disease 2019 (COVID-19). We aimed to summarize and analyze these herbal medicines. Methods Nine databases were searched for studies published up until November 24, 2020. Nine case reports and one case series involving 17 pediatric patients were included in the study. The clinical symptoms, interventions, outcomes, pattern identification, composition, and frequency of herbal medicine administration were analyzed. Results The symptoms of pediatric patients with COVID-19 treated with herbal medicines were mild or moderate. Herbal medicines have been used to alleviate symptoms, such as fever and cough. No adverse events were reported. All of the patients who received herbal medicines were discharged from the hospital after symptomatic relief. Pattern identification revealed that the lungs were the most affected organs. Epidemic toxins, wind, dampness, and heat were the primary etiological factors. More pediatric patients with COVID-19 were prescribed a combination of herbal and Western medicines than herbal medicines alone. The frequently used herbs include Glycyrrhizae Radix et Rhizoma, Lonicerae Flos, Scutellariae Radix, Armeniacae Semen, Citri Reticulatae Pericarpium, and Astragali Radix. Conclusions Our review can serve as a reference for the treatment of COVID-19 in children.

• 사상체질의학회지
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• 제23권3호
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• pp.275-284
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• 2011

1. Objective: This literary review investigates Lee Jema's clinical experiences with Soyang-type patients and their influence on his conceptualization of the Soyang physiology and pathology. 2. Methods: 1) The case reports in "Soyang constitutional type: Spleen Cold-based Exterior-Cold disease" were compared before and after the Sinchuk revision to explore the temporal change in the Sasang medical concepts. 2) The texts in Donguisusebowon (Gabo edition) and Donguisusebowon (Sasangchobongwon) were analyzed to investigate the pathological concepts appearing before the completion of the Donguisusebowon (Gabo edition). 3) The texts in Donguisusebowon (Sinchuk edition) was analyzed to investigate the pathological concepts formed between the Gabo and Sinchuk editions of Donguisusebowon. 3. Results and Conclusions: 1) Gabo edition : The Gabo edition divided the External-origin Exterior disease into Cold-dominant (Heat-moderate) and Heat-dominant (Cold-moderate) patterns and differentiated the severity of Exterior-based Exterior disease and Interior-based Interior disease into mild, moderate, severe, and critical conditions. Cold-damage Delirium disease pattern was categorized as an Interior-based Interior disease, and the treatment protocol using Baekho-tang (Baihu-tang) was established. The stool condition and bowel movement reflecting the patient's defecation habits, the prime indicator of health in the Soyang constitutional type, were emphasized on their importance. 2) Sinchuk edition: The Delirium disease pattern was moved into the Exterior-cold disease, and the treatment protocol applying Jihwangbaekho-tang (Dihuangbaihu-tang) and Hyeongbangsabaek-san (Jingfangxiebai-san), with variational usage of Gypsum, was newly established. The Seong-Jeong and basal disease patterns were suggested as important factors in treating the patients. Also, it was proposed that the symptoms and signs reflecting the condition of the life-preserving energy be assessed to understand the patient's current condition. The importance of post-acute rehabilitation and aftercare as well as the most appropriate acute-stage treatment were emphasized.

• 동의생리병리학회지
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• 제21권1호
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• pp.333-337
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• 2007

Cellulitis is a infectious disease characterized by acute purulent inflammation clinically manifested by erythema, pain or heating sensation caused by palpation, chilling sign and mild to moderate fever. in western medicine most part of the treatment is focused on injecting routine antibiotics hoping for the pathogen(in the case bacteria) to be treated but instead causing the bacteria to be resistant to antibiotics and consequently leads to longer admission. In oriental medicine Cellulitis belongs to the cathegory of Ong(癰), Bal(發) or Dandok(丹毒) on symptoms. The chief cause of acute Cellulitis is the evil of wet and heat blended and the postraumatic infection evil. We experienced a case of acute cellulitis defined as Bicheonbal(비천발) and Chokbaebal(足背發). We attempted to use both methods using acupuncture, herbal medicine(Gamidangkwuijeomtong-tang(加味當歸拈痛湯)) as well as routine antibiotic treatment and as a result we have achieved remarkable results in laboratory tests though there was no difference in shortening the curing process compared to the average time that it take to cure when admitted to western medical center.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제39권4호
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• pp.193-196
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• 2013

Artecoll (Artes Medical Inc., San Diego, CA, USA) has recently been developed as a permanent synthetic cosmetic filler. We experienced an inflammatory granuloma resulting from a previous injection of Artecoll at the upper lip, which was regarded as a rare side effect of this filler. A 50-year-old female patient complained of swelling, dull pain, and heat in the right upper nasolabial fold area, which had started one week before her visit to Kyungpook National University Hospital. The patient received topical steroid therapy at a local clinic, which was not effective. At the injection site, a hard nodule was palpated and erythema was observed with mild tenderness. Antibiotic treatment and subsequent incision and drainage did not result in complete cure of the facial swelling, and the facial swelling and pain persisted. Computed tomography showed a lesion approximately 1-cm in size without clear boundaries and relatively increased nodular thickening. Finally, a subdermal lesion was removed via an intraoral vestibular approach. The lesion was diagnosed as inflammatory granuloma by a permanent biopsy. The patient had healed at two months after the filler injection. Although the soft tissue filler is widely used for cosmetic purposes, there is potential for complication, such as the inflammatory granuloma should be considered before treatment.