• Journal of Communications and Networks
• /
• v.8 no.1
• /
• pp.123-131
• /
• 2006

Several distributed architectures, incorporating mobile agent technology, have been recently proposed to answer the scalability limitations of their centralized counterparts. However, these architectures fail to address scalability problems, when distributed tasks requiring the employment of itinerant agents is considered. This is because they lack mechanisms that guarantee optimization of agents' itineraries so as to minimize the total migration cost in terms of the round-trip latency and the incurred traffic. This is of particular importance when MAs itineraries span multiple subnets. The work presented herein aspires to address these issues. To that end, we have designed and implemented an algorithm that adapts methods usually applied for addressing network design problems in the specific area of mobile agent itinerary planning. The algorithm not only suggests the optimal number of mobile agents that minimize the overall cost but also constructs optimal itineraries for each of them. The algorithm implementation has been integrated into our mobile agent framework research prototype and tested in real network environments, demonstrating significant cost savings.

• Proceedings of the CALSEC Conference
• /
• 2005.03a
• /
• pp.149-154
• /
• 2005

Recently, lots of EDI-VAN (Electronic Data Interchange-Value Added Network) companies challenge to convert their business systems into Web-based e-business frameworks to avoid high cost and closed structure of EDI system. This research proposes e-Transformation strategies for EDI-VAN companies to adopt Web-based e-business standard frameworks such as ebXML (e-business using XML) and RosettaNet. Four migration strategies for EDI companies are presented, and their properties are described in detail. Transformation procedures of two representative strategies are also provided fur the convenience of medium-sized companies. The result of this work can be used as a practical guideline for EDI companies to develop there own transformation strategy suitable to its scale and capability, while minimizing the impacts on the pre-existing business processes.

• Proceedings of the KSEEG Conference
• /
• 2002.04a
• /
• pp.159-162
• /
• 2002

We tried to obtain an initial velocity model for prestack depth migration via waveform inversion. For application of any field data we chose a smooth background layered velocity model (v=v0 + k x z) as an initial velocity model. Newton type waveform inversion needs to invert huge Hessian matrix. In order to compute full Hessian matrix arising from full aperture data and full illumination zone, we meet insurmountable difficulties of paying astronomical computing cost. For the layered media, approximate Hessian emerging from single shot aperture data can be used repeatedly for split spread source configuration. In our work of using this Hessian characteristic of layered media we attempted to obtain the approximate velocity model as close as possible to the true velocity model in first iteration.

• Current Optics and Photonics
• /
• v.1 no.5
• /
• pp.551-555
• /
• 2017

Tissue optics is a well-established and extensively studied area. In the last decades, Monte Carlo simulation (MCS) has been one of the standard tools for simulation of light propagation in turbid media. The utilization of parallel processing exhibits dramatic increase in the speed of MCS's of photon migration. Some calculations based on MCS can be completed within a few seconds. Since the MCS's have the potential to become a real time calculation method, a dynamic accuracy estimation, which is also known as history by history statistical estimators, is required in the simulation code to automatically terminate the MCS as the results' accuracy achieves a high enough level. In this work, spatial and time-domain GPU-based MCS, adopting the dynamic accuracy estimation, are performed to calculate the light dose/reflectance in homogeneous and heterogeneous tissue media. This dynamic accuracy estimation can effectively derive the statistical error of optical dose/reflectance during the parallel Monte Carlo process.

• Biomolecules & Therapeutics
• /
• v.19 no.4
• /
• pp.390-397
• /
• 2011

G protein-coupled receptor kinases (GRKs) and ${\beta}$-arrestins have been known as regulators of G protein-coupled receptors. However, it has been recently reported that GRKs and ${\beta}$-arrestins mediate receptor-mediated cellular responses in a G proteinin-dependent manner. In this scheme, GRKs work as a mediator or a scaffold protein. Among 7 members of the GRK family (GRK1-GRK7), GRK2 is the most extensively studied in vitro and in vivo. GRK2 is involved in cellular migration, insulin signaling, and cardiovascular disease. GRK6 in concert with ${\beta}$-arrestin 2 mediates chemoattractant-stimulated chemotaxis of T and B lymphocytes. GRK5 shuttles between the cytosol and nucleus, and regulates the activities of transcription factors. GRK3 and GRK4 do not seem to have striking effects on cellular responses other than receptor regulation. GRK1 and GRK7 play specific roles in regulation of rhodopsin function. In this review, these newly discovered functions of GRKs are briefly described.

• Journal of Information Technology Applications and Management
• /
• v.25 no.4
• /
• pp.67-77
• /
• 2018

With the types and targets of cyber attacks expanding and with personal information leaks increasing, the quantitative demand for information security specialists has increased. The base for training the workforce has expanded accordingly, but joblessness and job-seeking still coexist. To resolve the gap between labor demand and supply, education and training systems that can supply demand quickly are needed. It takes a considerable amount of time for information security education and new manpower supply through universities and graduate schools to be reflected in the market. However, if information security retraining is carried out in terms of career development of information security and related workforce, the problem of lack of experts could be solved in a relatively short period. This paper investigates and analyzes the information security work of the information security workforce, the degree of skill level, the need for retraining, and the workplace migration experience; it also discusses the direction of career development retraining.

• Journal of the Korean Society for Heat Treatment
• /
• v.32 no.1
• /
• pp.1-11
• /
• 2019

In this study, microstructure evolution and crystallographic orientation are investigated under various deformation conditions in M1 magnesium alloy. M1 magnesium ingot was rolled at 673 K with the rolling reduction of 30%. The compression test specimens were machined out from rolled plate, and then the specimens were annealed at 823 K for 1h. Uniaxial compression tests were conducted at 723 K and under the strain rate ranging from $5.0{\times}10^{-4}s^{-1}$ to $5.0{\times}10^{-2}s^{-1}$ up to a true strain of -1.0. For observation of crystal orientation distribution, EBSD measurement was performed. Occurrence of the dynamic recrystallization and grain boundary migration were confirmed in all case of the specimens. The distribution of the grains is not uniformed in the experimental conditions.

• Economic and Environmental Geology
• /
• v.55 no.6
• /
• pp.597-616
• /
• 2022

The Chungnam basin is a crucial area for studying the Mesozoic crustal evolutionary history of the Korean Peninsula. This study reports the revised geology and new isotopic ages from the northeastern Chungnam Basin based on detailed geological mapping and LA-ICP-MS zircon U-Pb analysis. Our renewed geologic map defines intra-basin, basin-bounding, and basement fault systems closely related to hydrothermal gold-bearing quartz vein injections. Here, we propose the directions of (micro)structural and geochronological future work to address issues on the relationship between the tectonic process, basin evolution, and hydrothermal fluid migration in the southwestern Korean Peninsula.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.7
• /
• pp.3043-3050
• /
• 2015

The tumor microenvironment (TME) includes numerous non-neoplastic cells such as leukocytes and fibroblasts that surround the neoplasm and influence its growth. Tumor-associated macrophages (TAMs) and cancerassociated fibroblasts (CAFs) are documented as key players in facilitating cancer appearance and progression. Alteration of the macrophage (CD68, CD163) and fibroblast (${\alpha}-SMA$, FSP-1) cells in Opisthorchis viverrini (Ov) -induced cholangiocarcinoma (CCA) was here assessed using liver tissues from an established hamster model and from 43 human cases using immunohistochemistry. We further investigated whether M2-activated TAMs influence CCA cell migration ability by wound healing assay and Western blot analysis. Macrophages and fibroblasts change their phenotypes to M2-TAMs (CD68+, CD163+) and CAFs (${\alpha}-SMA+$, FSP-1+), respectively in the early stages of carcinogenesis. Interestingly, a high density of the M2-TAMs CCA in patients is significantly associated with the presence of extrahepatic metastases (p=0.021). Similarly, CD163+ CCA cells are correlated with metastases (p=0.002), and they may be representative of an epithelial-to-mesenchymal transition (EMT) with increased metastatic activity. We further showed that M2-TAM conditioned medium can induce CCA cell migration as well as increase N-cadherin expression (mesenchymal marker). The present work revealed that significant TME changes occur at an early stage of Ov-induced carcinogenesis and that M2-TAMs are key factors contributing to CCA metastasis, possibly via EMT processes.

• The Journal of the Institute of Internet, Broadcasting and Communication
• /
• v.10 no.5
• /
• pp.45-55
• /
• 2010

While Long Term Evolution-Frequency Division Duplexing (LTE-FDD) is regarded as one of the strong candidates for "4G" wireless broadband access in FDD field, LTE-Time Division Duplexing (TDD) is emerging as one possible migration path for WiMAX-TDD in some cases as well as the migration path for Time Division-Synchronous Code Division Multiple Access (TD-SCDMA). In this paper, we analyze the feasibility of dual mode with LTE-TDD in two combinations: dual mode LTE-FDD/TDD and dual mode Worldwide Interoperability for Microwave Access (WiMAX)-TDD/LTE-TDD. Thanks to the commonality in numerology, terminology, and frame structure between LTE-FDD and LTE-TDD, dual mode LTE-FDD/TDD looks feasible in a cost-effective manner. Thanks to the commonality in scheduling algorithm, control mechanism, and supported spectrum bands, it is shown that dual mode WiMAX-TDD/LTE-TDD looks feasible as well. It should be also noted that the commonality in numerology and frame structure is critical for building a chip while the commonality in algorithms and control mechanisms is critical to make it work.