• 센서학회지
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• 제18권2호
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• pp.122-127
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• 2009

We have developed and reported several micro-spikes for minimally invasive biopsy. In this paper, a micro-tissue collecting tool for tissue diagnosis extracted by micro-spike is presented. Using proposed polydimethy-siloxane (PDMS) micro-tissue collecting tool, which has a negative micro-spike structure in a porous chamber, the extracted tissue in a micro-spike is effectively detached. The gastro-intestinal tissue of a pig is extracted in an in vivo environment, and then it is detached from a micro-spike using the PDMS micro-tissue collecting tool. A fine clinical picture of the detached tissue is acquired.

• 대한의용생체공학회:의공학회지
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• 제31권3호
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• pp.234-239
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• 2010

We have developed and reported several micro-spikes for minimally invasive biopsy. This paper presents a diagnosis protocol for micro-spike biopsy using paraffin-based tissue collecting tool. Using the proposed tissue collecting tool, which has a negative micro-spike structure in a porous chamber, the biopsied tissue in a micro-spike is effectively detached. The proposed diagnosis protocol prevents the loss of tissues in a paraffin embedding and sectioning process. Hence, it is compatible with conventional histopathology without additional reagents and processes. The gastro-intestinal tissue of a pig is biopsied in an in vivo environment, and then it is detached from a micro-spike using the paraffin-based tissue collecting tool. A histopathological photomicrograph of the detached tissue is acquired with the proposed diagnosis protocol. The acquired image offers clinical quality. This result shows that the paraffin-based tissue collecting tool is applicable to the medical practice.

• Design & Manufacturing
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• 제17권2호
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• pp.55-61
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• 2023

With femtosecond (fs) laser pulse irradiation on metals, various types of nano- and micro-scale structures can be naturally induced at the surface through laser-matter interaction. Two notable structures are laser-induced periodic surface structures (LIPSSs) and cone/spike structures, which are known to significantly modify the optical and physical properties of metal surfaces. In this work, we irradiate fs laser pulses onto various types of metals, cold-rolled steel, pickled & oiled steel, Fe-18Cr-8Ni alloy, Zn-Mg-Al alloy coated steel, and pure Cu which can be useful for precise molding and imprinting processes, and adjust the morphological profiles of LIPSSs and cone/spike structures for clear structural coloration and a larger range of surface wettability control, respectively, by changing the fluence of laser and the speed of raster scan. The periods of LIPSSs on metals used in our experiments are nearly independent of laser fluence. Accordingly, the structural coloration of the surface with LIPSSs can be optimized with the morphological profile of LIPSSs, controlled only by the speed of the raster scan once the laser fluence is determined for each metal sample. However, different from LIPSSs, we demonstrate that the morphological profiles of the cone/spike structures, including their size, shape, and density, can be manipulated with both the laser fluence and the raster scan speed to increase a change in the contact angle. By injection molding and imprinting processes, it is expected that fs laser-induced surface structures on metals can be replicated to the plastic surfaces and potentially beneficial to control the optical and wetting properties of the surface of injection molded and imprinted products.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2000년도 춘계학술대회논문집A
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• pp.760-765
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• 2000

The study deals with the development of a computational procedure for evaluating the temperature rise in dry and lubricated multi-layered contacts of head/disk interface. A transient computational model with a transformed rectangular computational domain is utilized. A model and a computational method for micro-contact with sub-lubricated zone, including friction heat generation, have been presented. The model was applied, taking full account of the changes in contact area and contact load due to frictional heating. The computational distribution of temperature is obtained with the analytical findings for various composition and contact conditions. Especially, a rapid rise ($220^{\circ}C$ or above) in read head temperature lese to a saturation in the influence of a thermal spike on signal performance. This general class of problems can be treated provided that heat generation distribution and layer properties are known.

• 한국가시화정보학회:학술대회논문집
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• 한국가시화정보학회 2004년도 Proceedings of 2004 Korea-Japan Joint Seminar on Particle Image Velocimetry
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• pp.75-80
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• 2004

Aerospike nozzles have been expected to be used for an engine of a reusable space shuttle to respond to growing demand for rocket-launching and its cost reduction. In this study, the flow field structures in any cross sections around clustered linear aerospike nozzles are visualized and analyzed, using laser induced fluorescence (LIF) of nitrogen monoxide seeded in the carrier gas of nitrogen. Since flow field structures are affected mainly by pressure ratio, the clustered linear aerospike nozzle is set inside a vacuum chamber to carry out the experiments in the wide range of pressure ratios from 75 to 200. Flow fields are visualized in several cross-sections, demonstrating the complicated three-dimensional flow field structures. Pressure sensitive paint (PSP) of PtTFPP bound by poly- IBM -co-TFEM is also applied to measurement of the complicated pressure distribution on the spike surface, and to verification of contribution of a truncation plane to the thrust. Finally, to examine the effect of the sidewalls attached to the aerospike nozzle, the flow fields around the nozzle with the sidewalls are compared with those without sidewalls.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1993년도 하계학술대회 논문집 B
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• pp.781-783
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• 1993

The GTO model is based on the Ebers-Moll equation extened to include the three-junction devices and a detailed description of the implementation of the model equation as well as defferent tests are discussed. Problems to be considered for the snubber design, such as voltage spike reduction, maximum GTO anode current, and switching power, were discussed using the calculation model. The macro model is very useful for simulation of GTO circuit and high power circuit switch in high frequency and complex structure.

• 산업경영시스템학회지
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• 제43권2호
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• pp.1-13
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• 2020

There are several methods of peak-shaving, which reduces grid power demand, electricity bought from electricity utility, through lowering "demand spike" during On-Peak period. An optimization method using linear programming is proposed, which can be used to perform peak-shaving of grid power demand for grid-connected PV+ system. Proposed peak shaving method is based on the forecast data for electricity load and photovoltaic power generation. Results from proposed method are compared with those from On-Off and Real Time methods which do not need forecast data. The results also compared to those from ideal case, an optimization method which use measured data for forecast data, that is, error-free forecast data. To see the effects of forecast error 36 error scenarios are developed, which consider error types of forecast, nMAE (normalizes Mean Absolute Error) for photovoltaic power forecast and MAPE (Mean Absolute Percentage Error) for load demand forecast. And the effects of forecast error are investigated including critical error scenarios which provide worse results compared to those of other scenarios. It is shown that proposed peak shaving method are much better than On-Off and Real Time methods under almost all the scenario of forecast error. And it is also shown that the results from our method are not so bad compared to the ideal case using error-free forecast.

• 한국작물학회지
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• 제47권5호
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• pp.379-383
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• 2002

Allelic diversity of 44 microsatellite marker loci originated from the coding regions of specific genes or the non-coding regions of barley genome was analyzed for 19 barley genotypes. Multi-allelic variation was observed at the most of marker loci except for HVM13, HVM15, HVM22, and HVM64. The number of different alleles ranged from 2 to 12 with a mean of 4.0 alleles per micro-satellite. Twenty-one alleles derived from 10 marker loci are specific for certain genotypes. The level of polymorphism (Polymorphic Information Content, PIC) based on the band pattern frequencies among genotypes was relatively high at the several loci such as HVM3, HVM5, HVM14, HVM36, HVM62 and HVM67. In the cluster analysis using genetic similarity matrix calculated from microsatellite-derived DNA profiles, two major groups were classified and the spike-row type was a major factor for clustering. Correlation between genetic similarity matrices based on microsatellite markers and pedigree data was highly significant ($r=0.57^{**}$), but these two parameters were moderately associated each other. On the other hand, RAPD-based genetic similarity matrix was more highly associated with microsatellite-based genetic similarity ($r=0.63^{**}$) than coefficient of parentage.

• 전력전자학회논문지
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• 제18권5호
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• pp.477-484
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• 2013

This paper proposes a novel switching method of active clamp snubber for efficiency improvement of PV module integrated converter(MIC) system. Recently, MIC solar system is researched about the efficiency and safety. PV MIC system is used active clamp method of snubber circuit for the price and reliability of the system. But active clamp snubber circuit has the disadvantage that system efficiency is decreased for switch operating time because of heat loss of resonant between snubber capacitor and leakage inductance. To solve this problem, this paper proposes a novel switching method of the active clamp. The proposed method is a technique to reduce power consumption by reducing the resonance of the snubber switch operation time and through simulations and experiments proved the validity.

• 한국방사선학회논문지
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• 제12권6호
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• pp.777-783
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• 2018

고무화합물 형태로 구성된 조영제의 병에 Syringe Connector의 Spike를 연결 시 고무의 찢김 정도를 알아 보고 찢김 및 분쇄로 인한 합성고무의 혼입 유무와 분쇄된 합성고무가 검출 시 분쇄물의 크기를 실험을 통해 알아보고자 하였다. 그 결과 찢김 정도의 경우 Syringe Connector의 끝과 최초 접촉하는 앞면이 약 $3.14{\pm}0.04mm$로 뒷면 보다 많이 찢겼으며, 실험 대상인 10 병의 조영제에서 평균 7 개에서 15 개로 모두 분쇄물이 검출되었다. 검출된 분쇄물을 이용하여 크기를 측정한 결과 평균크기는 약 $7.89{\pm}0.31{\mu}m$이었다. 향 후 다양한 실험 및 분석방법을 통한 추가실험과 더불어 흡인된 분쇄물 차단을 위한 미세 필터타입 자동주입장치의 개발이 필요하며, 분쇄물 유입 시 치명적 사고를 대비하여 관련기관의 관심 또한 필요할 것으로 사료된다.