• Journal of Korea Technology Innovation Society
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• v.6 no.4
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• pp.429-446
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• 2003

The status of microfactory or microfactory-related research in some advanced countries are investigated. Under the financial support of government, Japan has accomplished the Microfactory Project, the United States has pursued the Micro/Meso mMf project, and European countries have been studying micro assembly systems. In Korea, several universities and some large manufacturers have participated in the development of micro-components or micrcrdevices based on MEMS technology since the late 1990's. Microfactory is a process which achieves an integrated micro-manufacturing system in a production system, which is followed by the steps of micro-technology of machine parts based on micro-system technology. In addition, this process is a new concept of manufacturing system that renovates the existing manufacturing system It is sure that the research of micro- manufacturing technology must lead to nano-technology in the near future, with intensive financial supports of government for this technology.

• 제어로봇시스템학회:학술대회논문집
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• 2004.08a
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• pp.1945-1948
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• 2004

This paper describes the design and construction of a micro robotic system addressing such important aspects as versatility and low cost for rapid development and test of new control algorithm. The design and structure of micro robots are presented in detail. The supervision oriented concept is designed for controlling a group of micro robots. In this concept, the vision system recognizes the environment and the host computer decides the micro robot action based on the information from the vision system. In addition, the micro robots can be implemented cheaply and small in size because the structure of supervision oriented system is simplest. The experimental results and the performance of the proposed micro robotic system are discussed.

• 제어로봇시스템학회:학술대회논문집
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• 2003.10a
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• pp.1344-1348
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• 2003

A precision micro-positioning system with a high displacement resolution and wide motion range has been required for industrialized applications in variety fields. This paper discusses the design of a precision micro-rotation stage with flexure hinges. Proposed system is applied to grinding machine for micro parts. Rotational motion is generated with this system. For this systems having a full rotation motion with high precision, a dual servo system with a coarse stage and a fine stage is proposed.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2003.05a
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• pp.452-457
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• 2003

As a fundamental study on developing elements with micro shape, micro mold parts machining and experiment of injection molding using it were performed. The ultra precision micro machining system with high functionality was fabricated, and utilized in the machining of micro parts. By using this machining system and micro end-mill tool, a micro circle column structure of high aspect ratio, diameter 60 $\mu\textrm{m}$, height 500 $\mu\textrm{m}$, was fabricated. And a micro lens molds were fabricated by using ball end-mill tool of 300 $\mu\textrm{m}$ diameter and diamond fly-cut tool of 150 $\mu\textrm{m}$ radius. A micro injection molding machine, which is clamping force 1.75 ton, injection capacity 2.8cc, was fabricated for injection molding experiment using micro molds. The injection molding experiment was performed by using the injection molding machine, micro cylinder structures and lens molds. This paper introduces these micro machining system and injection molding machine and demonstrates examples of injection molding using fabricated molds.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2003.04a
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• pp.167-172
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• 2003

The machining method by using end-milling tool has been applying in machining structures of various shapes because of the availability. Recently, all kinds of industries based on the parts of micro shape are developing, and the demands of mechanical micro machining technology are Increasing suddenly to produce these parts. According to such changes, the technology of the micro end-milling machining is applying as one of the most important machining means. This research is to aim at developing machining technology for various micro structures using micro end-mill. This paper introduces micro mechanical machining system with ultra precision, and demonstrates methods manufacturing all sorts of parts and moldings for industry and examples of applicable machining by using micro end-milling tool of micro sizes from hundreds to tens in diameter.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2004.04a
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• pp.459-465
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• 2004

Micro-factory is a small system to produce a small parts and this manufacturing system has advantages such as energy saving, resources saving, and manufacturing space saving. Micro-factory are classified according to production type and has many applications in various industry. In this paper, the basic concept and applications of micro-factory are introduced.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.16 no.3
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• pp.44-49
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• 2007

Recent manufacturing system requires development on new production technology to enable prompt manufacturing of diverse products. Most of the researchers have been working on micro-factory. Especially, focus on manufacturing of micro parts. Present manufacturing system consumes excessive resources in the form of energy and space to manufacture the micro parts. In this study, the micro lens module assembly system was modeled, analyzed with MST(Micro System Technology) Application Module and simulated through UML Language (Unified Modeling Language) with object-oriented logical model analysis method. Digital model of micro-factory was modeled, to execute the new paradigm of digitalization on products, resources and processes of micro-factory.

• Journal of the Korean Society for Precision Engineering
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• v.23 no.12 s.189
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• pp.117-121
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• 2006

Generally, micro-stereolithography technology uses laser and complex optical system as light source and light delivery system, respectively. In this research, a novel micro-stereolithography technology that uses UV lamp that is more economical than UV laser as light source and optical fiber that is simpler than previous light delivery system has been developed. Furthermore, precise control system that is composed of 3-axis linear stage and shutter has been used to fabricate truly three dimensional micro-structure. For confirming the feasibility of developed micro-stereolithography apparatus, the solidification experiments were conducted. The solidification widths and depths datum of photopolymer as varying scanning speed of the UV light have been obtained. Using developed apparatus, some micro structures were fabricated successfully.

• Journal of Microbiology and Biotechnology
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• v.32 no.4
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• pp.531-540
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• 2022

Due to the high incidence of malignant melanoma, the establishment of in vitro models that recapitulate the tumor microenvironment is of great biological and clinical importance for tumor treatment and drug research. In this study, 3D printing technology was used to prepare GelMA/PEGDA composite scaffolds that mimic the microenvironment of human malignant melanoma cell (A375) growth and construct in vitro melanoma micro-models. The GelMA/PEGDA hybrid scaffold was tested by the mechanical property, cell live/dead assay, cell proliferation assay, cytoskeleton staining and drug loading assay. The growth of tumor cells in two- and three-dimensional culture systems and the anti-cancer effect of luteolin were evaluated using the live/dead staining method and the Cell Counting Kit-8 (CCK-8) method. The results showed a high aggregation of tumor cells on the 3D scaffold, which was suitable for long-term culture. Cytoskeleton staining and immunofluorescent protein staining were used to evaluate the degree of differentiation of tumor cells under 2D and 3D culture systems. The results indicated that 3D bioprinted scaffolds were more suitable for tumor cell expansion and differentiation, and the tumor cells were more aggressive. In addition, luteolin was time- and dose-dependent on tumor cells, and tumor cells in the 3D culture system were more resistant to the drug.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2007.05a
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• pp.379-382
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• 2007

The MEMS (Micro Electro Mechanical Systems) process is used in a micro/nano pattern manufacturing method. This method is based on the lithography technology. But the MEMS process has some problems such as complicated process, long processing time and high production costs. Many researchers are doing research in substitute manufacturing method to work out a solution to these problems. In this paper, we apply a dieless incremental forming technology to a substitute method of MEMS process. This dieless forming technology is using in the commercial scale sheet forming such as a prototype of automobile sheet parts. 5-axes CNC (Computerized Numeric Control) method are applied in this system to get a micro-scale dieless forming results. These 5-axes system are composed of precision AC servo motor stages (4-axes) and PZT actuator (1-axis). A PZT actuator is used in a precision actuating axis because it can be operated in the nano scale stroke resolution. This micro dieless incremental forming system has the advantage of minimization in manipulating distance and working space. As equipment and tools become smaller in size, minute inertia force and high natural frequency can be obtained. Therefore, high precision forming performance can be obtained. This allows the factory to quickly provide the customer with goods because the manufacturing system and process are reduced. To construct this micro manufacturing system, many technologies are necessary such as high stiffness frame, high precision actuating part, structural analysis, high precision tools and system control. To achieve the optimal forming quality, the micro dieless forming system is designed and made with high stiffness characteristic.