• Title/Summary/Keyword: miR-33

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Fabrication and Characterization of Silver-Coated Titanium Dioxide Nanoparticles for a Conductive Paste (은이 코팅된 이산화티탄 나노입자 및 도전성 페이스트 제조 특성)

  • Sim, Sang-Bo;Lee, Mi Chae;Bae, Dong-Sik
    • Korean Journal of Materials Research
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    • v.25 no.12
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    • pp.683-689
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    • 2015
  • In this study, the properties of Ag-coated $TiO_2$ nanoparticles were observed, while varying the molar ratio of water and $Ag^+$ for the surfactant and $TiO_2$. According to the XRD results, each nanoparticle showed a distinctive diffraction pattern. The intensity of the respective peaks and the sizes of the nanoparticles increased in the order of AT1($R_1=5$)(33.3 nm), AT2($R_1=10$)(38.1 nm), AT3($R_1=20$)(45.7 nm), AT4($R_1=40$)(48.6 nm) as well as AT5($R_2=0.2$, $R_3=0.5$)(41.4 nm), AT6($R_2=0.3$, $R_3=1$)(45.1 nm), AT7($R_2=0.5$, $R_3=1.5$)(49.3 nm), AT8($R_2=0.7$, $R_3=2$)(57.2 nm), which values were consistent with the results of the UV-Vis. spectrum. The surface resistance of the conductive pastes fabricated using the prepared Ag-coated $TiO_2$ nanoparticles exhibited a range 7.0~9.0($274{\sim}328{\mu}{\Omega}/cm^2$) times that of pure silver paste(ATP)($52{\mu}{\Omega}/cm^2$).

COMPARATIVE STUDY OF RORSCHACH RESPONSE CHARACTERISTICS BETWEEN ADHD WITHOUT DEPRESSION AND ADHD WITH DEPRESSION (우울 동반 여부에 따른 ADHD의 Rorschach 반응 특성 비교)

  • Lee, Sun-Mi;Lee, Moon-Suk;Cho, Eun-Cheong
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.14 no.2
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    • pp.174-182
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    • 2003
  • Objective:Present study compared the Rorschach responses characteristics between ADHD without depression and ADHD with depression. Method:60 children diagnosed ADHD(30 ADHD without depression and 30 ADHD with depression) were assessed with The Rorschach. Responses characteristics between two groups were compared by t test and ${\chi}^2$ test. Results:ADHD without depression had more Rorschach response ration and frequency, with statical significance, in m, M-, DV, (3r+(2)/R>.44 and Fr+rF=0, OR(3r+(2)/R>.33)=YES, pure H<2=YES, H+(H)+Hd+(Hd), FQ none, Sc than ADHD with depression. ADHD with depression had more Rorschach response ration and frequency, with statical significance, in p, H+(H)+Hd+(Hd), (Hd), M than ADHD without depression. Conclusion:This results suggest that we had better consider the impulsivity of idation and cognition for ADHD without depression, preferred introversive coping style for ADHD with depression in diagnosing and intervening.

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Interpolation Technique to Improve the Accuracy of RR-interval in Portable ECG Device (휴대형 심전계 장치의 RR 간격의 정확도 개선을 위한 보간법 개발)

  • Lee, Eun-Mi;Hong, Joo-Hyun;Cha, Eun-Jong;Lee, Tae-Soo
    • Journal of Biomedical Engineering Research
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    • v.31 no.4
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    • pp.316-320
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    • 2010
  • HRV(Heart rate variability) analysis parameter is widely used as an index to evaluate the autonomic nervous system and cardiac function. For reliable HRV analysis, we need to acquire the accurate ECG signals. Most of commercially available portable ECG devices have low sampling rate because of low power consumption and small size issues, which make it difficult to measure RR-interval accurately. This study is to improve the accuracy of RR-interval by developing R-wave interpolation technique, based on the morphological characteristics of the QRS complex. When the developed method was applied to ECG obtained at 200 Hz and the results were compared with 1000 Hz reference device, the error range decreased by 1.33 times in sitting and by 2.38 times in cycling exercise. Therefore, the proposed interpolation technique is thought to be useful to improve the accuracy of R-R interval in the portable ECG device with low sampling rate.

Effects of Professional Autonomy, Organizational Commitment, and Perceived Patient Safety Culture on Patient Safety Management Activities of Nurses in Medium and Small-Sized Hospitals (중소병원 간호사의 전문직 자율성, 조직몰입 및 환자안전문화인식이 환자안전관리활동에 미치는 영향)

  • Hwang, Hyun Jung;Lee, Yun Mi
    • Journal of Korean Critical Care Nursing
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    • v.10 no.1
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    • pp.63-74
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    • 2017
  • Purpose: The purpose of this study was to examine the effect of professional autonomy, organizational commitment, and perceived patient safety culture on patient safety management activities of nurses in medium and small-sized hospitals. Methods: A cross-sectional design was employed. Self-reported questionnaires were completed by 121 nurses with at least 3 months of working experience in medium and small-sized hospitals located in B city. Data were analyzed using descriptive statistics, a t-test, a one-way ANOVA, Pearson correlation coefficients, and a multiple regression analysis. Results: Professional autonomy (r=.22, p=.016), organizational commitment (r=.34, p<.001), and perceived patient safety culture (r=.55, p<.001) had a statistically significant positive correlation with patient safety management activities. The factors that might affect patient safety management activities were professional autonomy (${\beta}=.23$, p=.003) and perceived patient safety culture (${\beta}=.55$, p<.001). The explanatory power of these factors for patient safety management activities was 33.5% (F=21.19, p<.001). Conclusions: The development of repetitive and continuous education programs is needed to improve a nurse's professional autonomy and perceived patient safety culture.

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The Influence of Academic Self-efficacy, Empathy and Communication Skills on Problem Solving Ability in Nursing Students (간호대학생의 학업적 자기효능감, 공감능력과 의사소통능력이 문제해결능력에 미치는 영향)

  • Kim, Mi Sook
    • Journal of East-West Nursing Research
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    • v.28 no.2
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    • pp.104-111
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    • 2022
  • Purpose: This study aimed to investigate factors affecting the problem solving ability of nursing students. Methods: The data in this study was collected through structured questionnaires from September 1st to October 30th, 2021. Study participants were 172 fourth grade nursing students at four departments of nursing located in B and K city. IBM SPSS WIN v 21.0. program with t-test, ANOVA, Scheffe' test, Pearson's correlation coefficients, and hierarchical regression was used for data analysis. Results: The mean scores of academic self-efficacy was 3.88±051, empathy was 3.76±0.33, communication skills were 3.94±0.48, and problem solving ability was 3.70±0.40. There were significantly positive correlations between problem solving ability and academic self-efficacy (r=.45, p=<.001), empathy (r=.51, p=<.001), communication skills (r=.52, p=<.001), Factors affecting participants' problem solving ability were empathy (β=.31, p=<.001), and communication skills (β=.23, p=.006), which explained about 38.4% of the problem solving ability. Conclusion: In this study, it is necessary to develop curricular and non curricular nursing program that can strengthen empathy and good communication skills together when developing programs that increase problem solving ability.

Oral Bioavailability of Levosulpiride in Korean Healthy Male Volunteers (건강한 한국인 성인 남성에서 레보설피리드 제제의 생체이용률)

  • Lee, Jung-Min;Choi, Sung-Up;Kim, Hee-Kyu;Yoon, Mi-Kyeong;Kim, Se-Hee;Youm, Jeong-Rok;Choi, Young-Wook
    • Journal of Pharmaceutical Investigation
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    • v.33 no.3
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    • pp.201-208
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    • 2003
  • Pharmacokinetics and oral bioavailability of levosulpiride was determined in Korean healthy male volunteers. Thirty subjects received a single oral dose (25 mg) of a tablet in a randomized $2{\times}2$ cross-over design. The plasma concentrations of levosulpiride were measured by HPLC and compared with those reported in the literature. Pharmacokinetic parameters for $Isomeric^{\circledR}$ tablet (levosulpiride 25 mg) were revealed as follows: $AUC_{inf}\;737.1{\pm}176.9\;ng{\cdot}hr/ml,\;C_{max}\;56.4{\pm}20.1\;ng/ml,\;T_{max}\;4.2{\pm}1.6\;hr,\;K_a\;1.00{\pm}1.09\;hr^{-1},\;K_{el}\;0.08{\pm}0.02\;hr^{-1},\;and\;t_{1/2}\;8.8{\pm}1.9\;hr$. The rate constant of the absorption phase was obtained based on the first-order kinetics. In the aspect of bioavailability, $Isomeric^{\circledR}$ tablet was bioequivalent to the other product $(Levopride^{\circledR}\;tablet)$ available in the Korea market. Intersubject variations and race differences were show in comparison with the published data in the literature, even though there was a linear relationship between dose ad extent of bioavailability.

A study on Biodegradability of Vegetable Oil based EP Grease (식물유계 EP그리스의 생분해도 평가에 관한 연구)

  • Nam Kyung-Im;Kim Young-wun;Chung Keunwo;Cho Wonoh;Jeon In-sik;Chung Yong-Mi
    • Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
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    • 2003.11a
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    • pp.139-148
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    • 2003
  • In this study, biodegradable base Li-greases were prepared by using Li-soap thickener and vegetable oils such as soybean oil, rapeseed oil, castor oil and synthetic ester. Also, EP-greases were formulated by blending base Li-greases, anti-wear additives, EP additives, anti-oxidants and corrosion inhibitor etc. And EP-greases were characterized by analysing physical properties such as worked penetration, dropping point, 4-ball wear, extreme pressure, thermal properties etc. Biodegradability of base Li-greases and EP-greases were evaluated by CEC-L-33-A-93 method using several inoculums of domestic sewage treatment plant. As the results, biodegradability of vegetable oils were shown at the range of 97.1 to $98.4\%$. And biodegradability of base Li-greases and EP-greases were $86.2\%\;\~\;89.3\%\;and\;83.4\%\;\~\;90.0\%$ which were lower value than those o( vegetable oils due to effect of Li-soap thickener, respectively. Therefore, the EP-greases prepared in this study were easily biodegraded by microorgnism.

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A Study of Role Awareness, Role Conflict and Job Satisfaction for Hospital-based Home Care Nurses (병원중심 가정전문간호사의 역할인식, 역할갈등 및 직무만족)

  • Chung, Mi-Young
    • Journal of Korean Academic Society of Home Health Care Nursing
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    • v.11 no.1
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    • pp.33-43
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    • 2004
  • Purpose: This study is a descriptive research conducted for looking into the role awareness level. role conflicts, and job satisfaction among professional home care nurses in the field of hospital based home care nursing service. Method: 154 specialized home care nurses in 63 hospitals and clinics that are implementing home care programs were subject to the study. Result: 1. The level of role awareness among professional home care nurses was $4.47\pm0.41$ on average out of 5. 2. The average score for role conflicts was $3.87\pm0.61$ out of 5. 3. In terms of job satisfaction level. $3.33\pm0.71$ was scored out of 5. 4. It has been discovered that there are statistically significant positive correlations among role awareness level, role conflicts(r= .224, P= .005), and job satisfaction level(r= .166, P=.040), while a negative correlation was detected between role conflicts and job satisfaction level(r=-.210, P= .009). Conclusion: The level of role awareness among professional home care nurses in the field of hospital based home care nursing service was very high and job satisfaction level was high when the level of home care nursing antecedents was high and the organization structure of working place was independent. But the level of role conflicts coming out of the weakness of job-supporting system was high. So the realistic alternative such as the improvement of working environment by administrative, institutional support, is required to make up for this problem in the future.

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The Relationship Between Eating Disorders, Body Image, Depression and Self-Esteem among College Women

  • Sung, Mi-Hae
    • Korean Journal of Health Education and Promotion
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    • v.19 no.4
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    • pp.33-44
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    • 2002
  • This study was conducted to investigate the relationship between an eating disorder, body image, depression and self-esteem amongst a subject group of 282 college women between Jan.,1st and 30th,2002, to provide base data for eating disorder levels of college women and to provide base data for health control. The evaluative instrument was a constructive questionnaire that consisted of 8 items of general characteristics and weight control questions, 24 questions relating to eating disorders, 17 questions pertaining to body image, 10 questions pertaining to depression and 10 questions pertaining to self-esteem. To identify the levels of an eating disorder, body image, depression and self-esteem perceived by subjects, the researcher used means and SDs. To test the significance of a subject's eating disorder, body image, depression and self-esteem according to the BMI, the researcher used the t-test. To test the correlation between the BMI, an eating disorder, body image, depression and self-esteem, the researcher used Pearson correlation coefficient. The results of this study are as follows. The mean score for anorexia nervosa was 31.52 and the mean score for bulimia nervosa was 24.12. Differences between the underweight group and the normal weight group in the level of eating disorders were significant (t=-6.94, p=.000). There were high positive correlations between the BMI and an eating disorder (r=.383, p<.01), between an eating disorder and depression (r=.161, p<.01), between body image and self-esteem (r=.653, p<.01). In addition, there were high negative correlations between an eating disorder and body image (r=-.214, p<01), between an eating disorder and self-esteem (r=-.196, p<.01), between depression and body image (r=-.541, p<.01), and between depression and self-esteem (r=-.537, p<.01). These results indicate that Korean college women need more education and counseling on dietary habits. Also, the systemic efforts reestablish the social standard of the beauty should be taken. Further empirical and experimental studies would be required for investigating for the factors influencing the eating attitude of the college women and discriminating the variables affecting the various specific dimensions of the eating attitude.

A Study on the Factors Influencing Burnout of Psychiatric Ward Nurses -Violence Experience, Violence Coping, Social Support- (정신과병동 간호사의 소진 영향 요인에 관한 연구 -폭력경험, 폭력대처, 사회적지지)

  • Seo, Jeong-Won;Kang, Mi-Ran;Je, Nam-Joo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.7
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    • pp.393-405
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    • 2019
  • This study is descriptive survey research to find out factors which violence experience, violence coping and social support affect. This study aims at reducing burnout of psychiatry nurses and founding problem-oriented violence handling standardized intervention. The subjects were 204 nurses who have worked for more than a year in a hospital. The data collection period was conducted with structured survey from July 1, 2018 to August 31, 2018. Collected data was analysed with average, standard deviation, t-test, ANOVA, Pearson's Correlation confident, Multiple Regression and this data will go to by SPSS. The results of the study were as follows. 92.2% of psychiatry nurses are experiencing verbal violence, 92.2% are experiencing physical threat and 75.5% are experiencing physical violence. Relations between violence experience and violence coping(r=0.15. p<.027), violence experience and burnout(r=0.16, p<.017) were positive correlation. Relation between violence coping and social support(r=0.30, p<.001) was positive correlation, and social support and burnout(r=-0.28, p<.001) was negative correlated. Also we found out that nursing job satisfaction, social support and physical violence experience affect burnout. Which shows model's explanatory power was 33.3%. Therefore preventive discipline which can reduce violence experience of psychiatry nurses, founding systems to reinforce social support and creating circumstance where nursing job satisfaction can increase will help reduce burnout and serve better nursing.