• 정신신체의학
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• 제29권2호
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• pp.136-143
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• 2021

연구목적 코로나바이러스 사태로 인해 전세계가 보건 위기와 큰 혼란의 국면을 맞은 가운데, 특히 재난 상황에서 시민의 건강을 위해 노력하는 공공 근로자들의 신체적, 정신적 스트레스가 과중해지고 있다. 본 연구는 공공 근로자들의 정신적 스트레스를 분석하고자 했다. 방 법 본 연구에서는 광명시 정신건강복지센터 홈페이지를 통해 모집한 531명의 공공영역 종사자를 대상으로 한국판 지각된 스트레스 척 도(Perceived Stress Scale, PSS), 한국판 우울증 평가도구(Patient Health Questionnaire-9, PHQ-9), 한국판 사건 충격 척도 수정판(Impact Event Scale-Revised, IES-R-K)을 시행하였다. 결 과 분석 결과에 의하면 코로나 19 관련 종사자들은 중등도 이상의 지각된 스트레스 반응(85.2%), 우울증상(22.2%), 외상 후 스트레스 관련 증 상(38.8%)을 보여, 상당한 스트레스와 우울증상을 경험하는 상태로 나타났다. PSS 총점은 PHQ-9, IES-R 총 점 및 IES-R의 하위 척도별 점수와 유의한 상관관계를 보여, 주관적으로 지각된 스트레스 반응 정도가 우울 증상과 연관되어 있음을 시사하였다. PSS, PHQ-9, IES-R 총점은 각각 모두 연령과 음의 상관관계를 보였다. 즉, 연령이 직무 스트레스 반응과 번아웃에 대한 보호요인으로 작용할 가능성이 있다. 결 론 향후에 공공영역 종사자 들의 정신건강에 관한 추가적인 연구가 필요하겠으며 정신건강 관리 및 적절한 개입이 마련되어야 할 것으로 사료된다.

• 대한간호
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• 제29권3호
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• pp.36-48
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• 1990

This study was attempted to provide us with basic information on how to improve understanding with patients for operation, and to offer then better nursing and treatment. This kind of study will help scientific application to nursing practice and operating room. The data was collected by interviewing 29 patients who underwent the elective surgery under the general anesthesia at Y hospital in Seoul. The interview ran from October 15 to December 15, 1989. The research instrument was a anxiety measurement device (SAAI) originally developed by Spielberger, et al and modified by Jung-Tack Kim. 1. Hypothesis Testing Hypothesis one was that there would be a difference in state anxiety level according to a time difference in watiting for operation. This hypothesis was rejected(state.anxiety level one hour before operation P>.05, r-.747, State anxiety level half an hour before operation P>.05, r-.1550, state anxiety level just before operation, P>.05, r=.1099). However, state anxiety, evel appeared to be associated with a longer watiting period, like one day before operation (P<.05, r-.4628). Hypothesis two was that there would be a difference according to state anxiety level of patients for operation. This was rejected. (Change of blood perssure in systolie P>.05 r=.1082, Change of blood pressure in diastolic P>.05, r=.088, Change of pulse rate, P>.05, r-1.909) 2. Examining trait anxiety and state anxiety levels, the average level of trait anxiety was 42.034, and the average level of state anxiety one day before operation was 43,000. The average level of state anxiety was averaged 42.356 in a waiting room for operation. 3. Examining the state anxiety level by time period, the one hour before was 42.379 the level half an hour before 42.276, and the level just before operation 42.414. The low level of state anxiety was due to the fact that premedication was not eliminated. 4. Age and time period like one day before operation was related to state anxiety level (F=5.271, P<.0.01) and blood pressure in waiting room for operation. That is, state anxiety level and blood pressure of patients one day before operation appeared high. Sex was relation to changes of blood pressure ; the blood pressure of male patients appeard higer than of female patients. A marital status was also related anxiety level one hour before operation the married patient for operation showed a higher state anxiety level than that of the unmarried patient for operation. Education was similarily related to trait anxiety level in which highly educated patients show lower levels of trait anxiety than poorly educated ones. Motive for hospitalization was related to state anxiety level for patient one hour before operation (F=6.464, P<.05) likewise, patients who are supposed to undergo operation hastily showed higher levels of anxiety than patients who expect elective surgeries.

• 중환자간호학회지
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• 제13권1호
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• pp.1-14
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• 2020

Purpose : The purpose of this study was to identify the factors influencing the general hospital nurses' confidence about the advance directives (ADs). Methods : This is a descriptive cross-sectional study. A total of 105 nurses were asked questions about characteristics, knowledge, attitude, learning needs, and confidence the about ADs, using structured questionnaires. Data were analyzed by descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient, and multiple regression. Results : The mean scores of knowledge were 7.26±1.47; attitude, 2.80±0.31; learning needs, 4.22±0.62; and confidence, 2.57±0.74. It was observed that knowledge had significant correlations with attitude (r=.43, p<.001), learning needs (r=.29, p=.003), and confidence (r=.40, p<.001), and attitude had significant correlations with learning needs (r=.31, p=.001) and confidence (r=.45, p<.001). Using multiple regression analysis, it was found that confidence was significantly influenced by knowledge (β=.27, p=.007), attitude (β=.21, p=.043), and experience of nursing or counseling a patient who wrote ADs (β=-.19, p=.046). The explanatory power of this model was 37.9% (F=5.16, p<.001, R²=.379). Conclusions : These findings suggest the need to develop a program to enhance nurses' knowledge, positive attitude, and experience of nursing or counseling a patient who wrote ADs.

• 기본간호학회지
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• 제17권3호
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• pp.391-399
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• 2010

Purpose: This study was done to examine factors influencing loneliness in the elderly living in nursing homes. Method: The participants for this study were 150 adults, age 60 or over who had lived for one year or longer in two nursing homes in Gwangju. The questionnaires consisted of measurements of activities of daily living (ADL), social support and loneliness. Frequencies, percentages and means were used with Pearson correlation coefficients, t-test, ANOVA, and Scheffe test to analyze the data. The analysis was done with SPSS 12.0 Stepwise multiple regression was used to identify significant factors influencing loneliness in the elderly living in nursing homes. Results: Significant correlations were found between level of ADL and loneliness (r=-0.379, p<.001), support from friends and loneliness (r=-0.472, p<.001), and support from significant others and loneliness (r=-0.449, p<.001). Loneliness was significantly influenced by support from friends, ADL, and support from significant others. This regression model explained 29% of the variances in loneliness. Conclusion: The findings in this study suggest that improvement in support from friends and ADL can lead to a reduction in loneliness in the elderly living in nursing homes.

• 한국보건간호학회지
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• 제29권2호
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• pp.165-176
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• 2015

Purpose: This study was conducted to examine the relationships of depression symptom, self-esteem, and stress with health-related quality of life(HRQOL) in patients with hypertension registered to a community health center. Methods: This study was a correlational survey using a convenience sampling. A total of 110 patients diagnosed with hypertension were recruited from a health center in Gyeonggi-do. The questionnaires used were the Cardiovascular Disease Specific-HRQOL questionnaire, Center for Epidemiologic Studies Depression, Rosenberg Self-Esteem Scale, and Perceived Stress Scale. The acquired data were analyzed using IBM SPSS version 22.0. Multiple linear regression analysis was performed. Results: Moderate depression symptom(${\beta}=-.368$, p<.001), severe depression symptom (${\beta}=-.450$, p<.001), stress(${\beta}=-.339$, p=.001), and gender(${\beta}=-.148$, p=.049) were significant predictors for the HRQOL. Multiple linear regression showed that 51.8% ($R^2=.518$) of the variance in the HRQOL was explained. Conclusion: Based on these results, development of an intervention or education program, to decrease depression symptoms and stress is recommended. This may improve the HRQOL in patients with hypertension registered to a community health center.

• Journal of Microbiology and Biotechnology
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• 제22권12호
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• pp.1629-1635
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• 2012

Previously, we demonstrated that the erythropoietin receptor (EpoR) is present on fibroblasts, where it regulates focal contact. Here, we assessed whether this action of EpoR is involved in the reduced cell adhesion observed in colonocytes exposed to Clostridium difficile toxin A. EpoR was present and functionally active in cells of the human colonic epithelial cell line HT29 and epithelial cells of human colon tissues. Toxin A significantly decreased activating phosphorylations of EpoR and its downstream signaling molecules JAK-2 (Janus kinase 2) and STAT5 (signal transducer and activator of transcription 5). In vitro kinase assays confirmed that toxin A inhibited JAK 2 kinase activity. Pharmacological inhibition of JAK2 (with AG490) abrogated activating phosphorylations of EpoR and also decreased focal contacts in association with inactivation of paxillin, an essential focal adhesion molecule. In addition, AG490 treatment significantly decreased expression of occludin (a tight junction molecule) and tight junction levels. Taken together, these data suggest that inhibition of JAK2 by toxin A in colonocytes causes inactivation of EpoR, thereby enhancing the inhibition of focal contact formation and loss of tight junctions known to be associated with the enzymatic activity of toxin A.

• 컴퓨터교육학회논문지
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• 제17권2호
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• pp.21-29
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• 2014

우리나라 연구개발 수준에 비해 성과를 보호하려는 노력은 이를 따라가지 못하고 있다. 본 연구에서는 정부출연연구기관 연구자의 연구보안의식 수준과 보안교육실태를 파악하고 교육을 활성화하기 위한 제도화 방안에 대해 알아보았다. 37개의 미래창조과학부 산하 출연(연) 연구보안 책임자 및 실무자를 대상으로 설문조사와 심층인터뷰를 실시하였다. 조사결과, 출연(연) 연구원의 보안의식은 보통이하 수준이며, 보안의식을 높이기 위해 교육이 필요하며, 보안교육을 효율적으로 실행하기 위해서는 제도화가 필요하다고 응답하였다. 심층 인터뷰 결과 연구성과 보호를 위해 연구자 대상 보안교육의 제도화, 체계적인 보안교육 프로그램 개발, 기관장의 보안의지 강화, 연구보안 전담인력 및 예산 확보가 필요하다.

• 한국산학기술학회논문지
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• 제18권7호
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• pp.257-268
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• 2017

본 연구의 목적은 1형 당뇨병 자녀를 둔 부모의 불안, 당뇨관련 스트레스 및 외상 후 성장의 정도에 대해 알아보고, 일반적 특성 및 질병관련 특성에 따른 차이와 각 변수의 관련성을 알아보고자 하였다. 서술적 조사 연구로 자료수집은 2016년 1월 4일부터 29일까지 1형 당뇨 인터넷 카페에서 온라인 설문으로 이루어졌고 77명이 최종 분석에 포함되었다. 측정변수는 불안, 당뇨관련 스트레스, 외상 후 성장이었다. 통계분석은 t-test, Mann-Whitney U test, Kruskal-Wallis test와 Pearson correlation coefficient로 분석하였다. 연구결과 부모가 종교가 있는 경우 외상 후 성장이 유의하게 높았고(p<.05), 자녀의 연령이 6세 미만인 경우(p<.05), 저혈당 경험이 있는 경우(p<.05)와 당화혈색소가 높은 경우(p<.05) 부모의 불안과 스트레스가 높았다. 그 외의 변수에 따라서는 유의한 차이가 없었다. 상관관계에서는 불안과 스트레스가 정적 상관관계(r=.684, p<.001), 불안과 스트레스와 외상 후 성장은 부적 상관관계(r=-.401, p<.001; r=-.327, p<.05)를 보였다. 본 연구의 결과를 통해 외상후 성장은 부정적인 정서를 감소시키는 역할을 할 수 있을 것으로 생각되며, 외상 후 성장을 도모할 수 있는 중재와 불안과 스트레스를 낮출 수 있는 중재가 필요한 것으로 판단된다.

• Toxicological Research
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• 제29권3호
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• pp.195-201
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• 2013

The anti-inflammatory effects of glycosaminoglycan (GAG) derived from Isaria sinclairii (IS) and of IS extracts were investigated in a complete Freund's adjuvant (CFA)-treated chronic arthritis rat model. Groups of rats were treated orally with 30 mg/kg one of the following: [1] saline control, extracts of [2] water-IS, [3] methanol-IS, [4] butanol-IS, [5] ethyl acetate-IS, or [6] Indomethacin(R) as the positive control for a period of two weeks. The anti-paw edema effects of the individual extracts were in the following order: water-IS ex. > methanol ex. > butanol ex. > ethyl acetate ex. The water/methanol extract from I. sinclairii remarkably inhibited UV-mediated upregulation of NF-${\kappa}B$ activity in transfected HaCaT cells. GAG as a water-soluble alcohol precipitated fraction also produced a noticeable anti-edema effect. This GAG also inhibited the pro-inflammatory cytokine levels of prostaglandin $E_2$-stimulated lipopolysaccharide in LAW 264.7 cells, cytokine TNF-${\alpha}$ production in splenocytes, and atherogenesis cytokine levels of vascular endothelial growth factor (VEGF) production in HUVEC cells in a dose-dependent manner. In the histological analysis, the LV dorsal root ganglion, including the articular cartilage, and linked to the paw-treated IS GAG, was repaired against CFA-induced cartilage destruction. Combined treatment with Indomethacin(R) (5 mg/kg) and IS GAG (10 mg/kg) also more effectively inhibited CFA-induced paw edema at 3 hr, 24 hr, and 48 hr to levels comparable to the anti-inflammatory drug, indomethacin. Thus, the IS GAG described here holds great promise as an anti-inflammatory drug in the future.

• Child Health Nursing Research
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• 제26권2호
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• pp.181-189
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• 2020

Purpose: This study explored the relationships of maturity fears and appearance interest(interest in appearance, interest in weight) with self-concept among girls with precocious puberty. Methods: The participants for this study were 120 elementary school students (8 to 10 years old) and their parents from two hospitals located in Chungcheong Province. Data were collected from January to February 2019 using self-reported questionnaires. The collected data were analyzed using descriptive statistics, the independent t-test, the Mann-Whitney U test, one-way analysis of variance, Pearson correlation coefficients, and multiple regression analysis in SPSS for Windows version 23.0. Results: Statistically significant negative correlations were found between self-concept and maturity fears (r=-.34, p<.001) and interest in weight (r=-.29, p=.001). Maturity fears were identified as a factor affecting the self-concept of girls with precocious puberty (β=-.34, p<.001). This variable explained 11.5% of the variance in the self-concept of girls who experienced precocious puberty. Conclusion: This study confirmed that maturity fears had a major influence on self-concept in girls with precocious puberty. The results of this study can be used as basic data for the development of a psychosocial nursing intervention program for girls who experience precocious puberty.