• Title/Summary/Keyword: miR-23a

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Factors Affecting the Stroke related Health-Promoting Lifestyle in Middle-Aged Adult (중년기 성인의 뇌졸중 관련 건강증진 생활양식의 영향요인)

  • Kim, Bo-Mi
    • Journal of Digital Convergence
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    • v.20 no.1
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    • pp.349-359
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    • 2022
  • This research is a descriptive study that aimed to identify the health knowledge related stroke, optimistic bias, and social support of middle-aged adults and the effect these had on their health-promoting lifestyle This study was conducted by collecting 220 adults aged between 40 to 60 years from C City D city and K city. Data were analyzed using descriptive analysis, ANOVA, t-test, Pearson's correlation coefficients and multiple regression with the SPSS 23.0 program. The average health-promoting lifestyle was 44.27 points. The health-promoting lifestyle of the study participants showed a positive correlation between the optimistic bias(r=.18, p=.001) and social support(r= .61, p<.000). According to the results of multiple regression analysis, perception of Necessity for Stroke Education(β=.12, p=.010), optimistic bias(β=.18, p=.040), and social support(β=.48, p<.000) were shown to be significant factors that affected the health-promoting lifestyle of the participants. These variables explained 38.5%. Therefore, an health education program to improve the health-promoting lifestyle related to stroke in adults should be considered as a way to enhance social support and reduce optimistic bias.

The Mediating Effect of Resilience on the Relationship between Clinic Practice Stress and Psychosocial Well-being of Nursing University Students (간호대학생의 임상실습 스트레스와 사회심리적 건강의 관계에서 회복탄력성의 매개효과)

  • Mi-Jung Kim;Eun-Ha Na
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.6
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    • pp.595-604
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    • 2023
  • This study attempted to provide basic data for developing strategies to improve the psychosocial well-being on nursing university students by identifying the mediating effect of resilience on the relationship between clinic practice stress and psychosocial well-being of nursing university students. The subjects of the study were 175 nursing students in their 3rd and 4th year who had clinic practice experience at two universities in J province and G city. The SPSS/23.0 program was used to analyze the data with descriptive statistics; an independent t-test, analysis of variance ANOVA, Pearson's correlation coefficient, and mediating effect analysis were performed using Process Macro 4.0. The psychosocial well-being of nursing university students showed a positive correlation with clinical practice stress (r=.472, p<.001), and a negative correlation with resilience (r=-.860, p<.001). Resilience showed a mediating effect on the relationship between clinical practice stress and psychosocial well-being. Based on the results of this study, it is necessary to development and apply systematic programs to reduce clinical practice stress and increase resilience for improving the psychosocial well-being of nursing university students.

Age and Growth of the Skipjack Tuna Katsuwonus pelamis in the Western and Central Pacific Ocean (중서부태평양 가다랑어(Katsuwonus pelamis)의 연령과 성장)

  • Ku, Jeong Eun;Lee, Sung Il;Kim, Jin-Koo;Park, Hee Won;Lee, Mi Kyung;Kim, Zang Geun;Lee, Dong Woo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.48 no.3
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    • pp.377-385
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    • 2015
  • The age and growth of the skipjack tuna Katsuwonus pelamis were determined using otoliths sampled from a Korean tuna purse seine fishery in the Western and Central Pacific Ocean from January 2005 to September 2006. A total of 312 otoliths were used to estimate the ages of skipjack tuna, which ranged from 1 to 7 years. The relationships between otolith ring radius (R) and fork length (FL) for female, male, and sex combined were FL = 19.74R + 1.50 ($r^2=0.54$), FL = 17.66R + 6.35 ($r^2=0.47$), and FL = 18.83R + 3.36 ($r^2=0.53$), respectively. The back-calculated fork lengths of each age ($FL_{year}$) were $FL_1=36.2cm$, $FL_2=43.3cm$, $FL_3=48.3cm$, $FL_4=52.6cm$, $FL_5=56.5cm$, $FL_6=60.8cm$, and $FL_7=63.2cm$. The relationships between fork length (FL) and total weight (TW) for female, male, and sex combined were $TW=0.00001FL^{3.19}(r^2=0.95)$, $TW=0.00001FL^{3.17}(r^2=0.95)$, and $TW=0.000009FL^{3.23}(r^2=0.95)$, respectively. The von Bertalanffy growth parameters of skipjack tuna estimated in this study were $L_{\infty}=77.4cm$, K = 0.176/year, and $t_0=-2.569years$.

Relationship between career decision/ behavior and the pre-/post satisfaction of dental hygiene students in field practice (치위생(학)과 학생들의 현장실습 전·후에 대한 만족 정도와 실습 후 진로의사 및 행동과의 관계)

  • Seong, Mi-Gyung;Hwang, Se-Hyun;Jang, Kyeung-Ae
    • Journal of Korean society of Dental Hygiene
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    • v.17 no.2
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    • pp.271-281
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    • 2017
  • Objectives: This study was conducted to promote the value of field practice courses by installing an efficient field practice program through understanding the relationship between career decision/ behavior and the pre-/post satisfaction of dental hygiene students in field practice. Methods: The subjects of the study were students in Gyeongnam and Busan majoring in dental hygiene, from which 218 questionnaires were obtained from 23 November 2015 to 30 July 2016. Results: In terms of career decision/ behavior, the post-satisfaction scores in ideas about their major, about whether it was helpful to selecting their speciality and positive impression of dental hygienists, interest and understanding in training course were significantly lower than the pre-satisfaction scores (p<0.05). Relationship between satisfaction in field training and career decision/ behavior following the field training, pre-/post-satisfaction on site-training content (r=0.371, p<0.01), pre-/post satisfaction in training instructions (r=0.267, p<0.01), and pre-/post-satisfaction in the training sites (r=0.436, p<0.01) were all proportionally correlated to the after-training career decision and behavior. Conclusions: It is necessary for training instructors to maintain close relationships with the students in field practice program courses. In advance, it is expected to promote students' satisfaction in field practice and serve as a starting point where students can build self-esteem as a future dental hygienist by positively influencing their career decisions and behaviors.

Factors Affecting Turnover Intention of Nurses Working in Neonatal Intensive Care Units (신생아 집중치료실 간호사의 이직의도에 미치는 영향요인)

  • Jun, Sun Hwa;Lee, Mi Hyang;Shim, Moon Sook;Lim, Hyo Nam
    • Journal of Korean Clinical Nursing Research
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    • v.27 no.1
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    • pp.45-53
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    • 2021
  • Purpose: This study was conducted to assess the factors affecting turnover intention of the nurses working in neonatal intensive care units, including the extent of fatigue, work stresses, and work overload related to infection control. Methods: This was a descriptive correlational study to test factors affecting the turnover intention of the nurses working in neonatal intensive care units. Data was analyzed utilizing descriptive statistics, t-test, One-way ANOVA, Pearsons' Correlation Coefficient, and multiple regressions by using the IBM SPSS Statistics 23.0 Program(IBM Corp., Armonk, NY). Results: The turnover intention of nurses had a positive correlation with the extent of fatigue (r=.54, p<.001), work stress (r=.40, p<.001), and with the work overload (r=.43, p<.001) related to infection control. In addition, factors affecting the turnover intention of nurses included the extent of fatigue (β=.52, p<.001) related to infection control and the number of pediatric patients assigned to each nurse (β=.26, p=.001) and the variances explained by the regression model was 37.0%. Conclusion: It is necessary to establish and implement strategies to lower the extent of fatigue related to infection control by reducing the nurses' workload. Securing additional nurses to ensure an appropriate number of pediatric patients assigned to each nurse, and providing efficient management and available resources to reduce the turnover intention of nurses working in neonatal intensive care units are suggested.

Investigation of the body distribution of load pressure and virtual wear design according to the corset type harness (코르셋 타입 하네스의 신체 하중압력 분포 측정 및 가상착의 적용)

  • Kwon, MiYeon;Choi, Sola;Kim, Juhea
    • Journal of the Korea Fashion and Costume Design Association
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    • v.23 no.3
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    • pp.1-10
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    • 2021
  • Harnesses are used in a variety of industries, such as rescue operations, medicine, and entertainment. However, conventional harnesses have problems as they are uncomfortable to wear and causes continuous pain. Therefore, in this study, the load and pressure applied to the body in the flying state when using a conventional harness were measured in real time and the distribution change was observed. Load and pressure were measured using a modified corset harness, a pressure sensor, and a human mannequin to measure the maximum and average pressure on the waist. As a result, it was confirmed that the load concentrated on the waist in the flying state was 104 N, and the pressure was applied to the left and right sides was 800 kPa or greater. The pressure distribution showed a pressure of 3-45 kPa in 73% in all measurable pressures. The results of the load and pressure distribution are presented as basic data for improving the wearability and reducing the discomfort of harnesses in the future, aid in the development of a harnesses that can minimize discomfort for various activities, and increase the concentration on experiential activities. In addition, using the CLO 3D program, which is a 3D virtual wearing system, a harness was put on a virtual model, and the compression level was checked and compared with the actual pressure distribution. As a result of comparing the measured pressure values in the flying state with the clothing pressure wearing the harness in the CLO 3D program, the total pressure value was found to be about 68% of the actual measured value. This helps develop a harness that can minimize discomfort during activities by predicting the load and pressure on the body by first applying new designs to a virtual wearing system during development. These new harness patterns can solve the problems of conventional harnesses.

Characteristic of Oviposition and Effect of Density Suppression by Yellow-colored Sticky Trap on Ricania shantungensis (Hemiptera: Ricaniidae) in Blueberry (블루베리에서 갈색날개매미충의 산란특성 및 황색끈끈이트랩의 산란 억제효과)

  • Kim, Dong Hwan;Kim, Hyeong Hwan;Yang, Chang Yeol;Kang, Taek Jun;Yoon, Jung Beom;Seo, Mi Hye
    • The Korean Journal of Pesticide Science
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    • v.20 no.4
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    • pp.281-285
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    • 2016
  • This study was conducted to investigate the characteristics of oviposition and the effect of density suppression by yellow-colored sticky trap on Ricania shantungensis in blueberry. The occurrence of an egg mass of R. shantungensis in the upper, middle and lower region were 56.6~60.2%, 23.8~28.1% and 11.7~19.7%, respectively. The number of egg masses in the branch was investigated. Percentage of the branch with one egg mass was greatest (50.9%) than with two (20.5%), three (14.6%) and over four (14.0%). The effect of yellow-colored sticky trap to reduce the number of R. shantungensis egg masses in blueberry was also investigated. In a month after yellow sticky trap installation, 17.1 adults of R. shantungensis were attracted per trap. Moreover, the number of egg masses on a tree in yellow-colored sticky trap plot was much lower (0.4) than control (1.3). Consequently, this result shows that use of yellow-colored sticky trap may contribute to decrease ovipisotion rate of R. shantungensis in blueberry.

Effects of Self-Leadership, Empathic Ability, and Depression on the Interpersonal Skills of Nursing Students (간호대학생의 셀프리더십, 공감능력과 우울이 대인관계능력에 미치는 영향)

  • Mi-Young Kim;Yooun-Sook Choi
    • Journal of The Korean Society of Integrative Medicine
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    • v.11 no.3
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    • pp.115-126
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    • 2023
  • Purpose : This study sought to determine the influence of nursing students' self-leadership, empathic ability, and depression on their interpersonal skills. Methods : This study applied a descriptive survey research design involving a self-report questionnaire. The participants were 315 nursing students in B city. Data were collected from April 27 to May 6, 2022. The data were analyzed using the percentage, mean, standard deviation, t-test, ANOVA, Scheffé test, Pearson's correlation coefficients, and multiple regression with IBM SPSS/WIN 23.0 program. Results : The participants' self-leadership score was 3.63±.65, their empathic ability score was 3.35±.40, their depression score was .84±.50, and their interpersonal skills score was 3.64±.80. Among the sub-categories, others' temperament scored the highest at 3.70±.86, followed by communication at 3.67±.86 and promoting relationships at 3.53±.86. Interpersonal skills were positively correlated with both self-leadership (r=.48, p<.001) and empathic ability (r=.33, p<.001). Self-leadership was positively correlated with empathic ability (r=.17, p<.05), but, negatively correlated with depression (r=.27, p<.001). The multiple regression analysis revealed, that the factors with the most significant effect on promoting relationships were, in descending order, self-leadership (β=.49, p<.001), empathic ability (β=.19, p<.001), and gender (β=.10, p=.033); the factors affecting others' temperament were, in descending order, self-leadership (β=.37, p<.001), empathic ability (β=.30, p<.001), severe depression (β=.14, p=.008), gender (β=.13, p=.010), and grade (β=-.13, p=.037); while the factors affecting communication were, in descending order, self-leadership (β=.41, p<.001), empathic ability (β=.23, p<.001), and gender (β=.11, p=.035). Moreover, the explanatory power of promoting relationships scored the highest at 31 %, followed by others' temperament at 27 % and communication at 26 %. Conclusion : The results of this study reveal the factors that influence the interpersonal skills of nursing students. To increase the interpersonal skills of nursing students, it is necessary to develop and apply regular curricula and programs designed to strengthen their self-leadership and empathic ability and to reduce their depression through reflecting differences between genders and grades.

Upregulation of miR-23b Enhances the Autologous Therapeutic Potential for Degenerative Arthritis by Targeting PRKACB in Synovial Fluid-Derived Mesenchymal Stem Cells from Patients

  • Ham, Onju;Lee, Chang Youn;Song, Byeong-Wook;Lee, Se-Yeon;Kim, Ran;Park, Jun-Hee;Lee, Jiyun;Seo, Hyang-Hee;Lee, Chae Yoon;Chung, Yong-An;Maeng, Lee-So;Lee, Min Young;Kim, Jongmin;Hwang, Jihwan;Woo, Dong Kyun;Chang, Woochul
    • Molecules and Cells
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    • v.37 no.6
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    • pp.449-456
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    • 2014
  • The use of synovial fluid-derived mesenchymal stem cells (SFMSCs) obtained from patients with degenerative arthropathy may serve as an alternative therapeutic strategy in osteoarthritis (OA) and rheumatoid arthritis (RA). For treatment of OA and RA patients, autologous transplantation of differentiated MSCs has several beneficial effects for cartilage regeneration including immunomodulatory activity. In this study, we induced chondrogenic differentiation of SFMSCs by inhibiting protein kinase A (PKA) with a small molecule and microRNA (miRNA). Chondrogenic differentiation was confirmed by PCR and immunocytochemistry using probes specific for aggrecan, the major cartilaginous proteoglycan gene. Absorbance of alcian blue stain to detect chondrogenic differentiation was increased in H-89 and/or miRNA-23b-transfected cells. Furthermore, expression of matrix metalloproteinase (MMP)-9 and MMP-2 was decreased in treated1 cells. Therefore, differentiation of SFMSCs into chondrocytes through inhibition of PKA signaling may be a therapeutic option for OA or RA patients.

Effects of a Prepared Childbirth Education on the Knowledge and Delivery Participation Levels of the Spouses of Primiparas (출산준비 교육이 초산모 배우자의 지식 및 분만참여에 미치는 효과)

  • Sung, Mi-Hae;Ju, Mi-Sook;Ju, Kyung-Sook
    • Women's Health Nursing
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    • v.9 no.3
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    • pp.213-223
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    • 2003
  • Purpose: This study was conducted to identify the effects of a prepared childbirth education on the knowledge and delivery participation levels of the spouses of primiparas. Method: The study's subjects were a convenience sample of 126 spouses, consisting of an experimental group of 74 educated for prepared childbirth for 10 hours. This study was measured by using a 41-item measurement instrument for knowledge of childbirth that was devised from Kang's(1981) instrument and a 23-item measurement instrument for measuring delivery levels which was developed through clinical experiences. The data gathered as analyzed by using SPSS WIN10.0. Result: There were no significant differences between the experimental group and the control group in homogeneity concerning the general characteristics of the spouses of primiparas. The first hypothesis, which stated that the level of knowledge of childbirth in the experimental group who received prepared childbirth education would be higher than in control group, was statistically supported by the Compared Independent Sample t-test(t=17.92, p=.000). The second hypothesis, which stated that the level of participation of delivery in the experimental group who received prepared childbirth education would be higher than in the control group, was also statistically supported (t=28.87, p=.000). The third hypothesis, which stated that there would be a correlation between the level of knowledge and the level of participation in the experimental group who received prepared childbirth education, showed a high positive correlation(r=.810, p=.000). Conclusion: The above results indicate that the increase of knowledge through prepared childbirth education in the spouses of primiparas has a high correlation with delivery partici- pation levels which engenders physical and moral support for primiparas at delivery. Additionally, a varied prepared childbirth education acts as an effective means to increase under- standing and support for primiparas couples who experience tension, anxiety and fear due to an unprepared delivery in Korea.

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