• 제목/요약/키워드: miR-126

검색결과 49건 처리시간 0.081초

조혈모세포이식 환자와 가족의 스트레스와 정서 상태에 대한 연구 (Stress and Emotional Status of Patients Undergone Hematopoietic Stem Cell Transplantation and Their Families)

  • 강혜령;홍윤진;황경아;박미라;전성숙;임난영
    • 재활간호학회지
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    • 제7권2호
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    • pp.115-126
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    • 2004
  • Purpose: This study was carried out to accumulate basic data for nursing intervention development by evaluating the stress and emotional status of patients and their families after receiving hematopoietic stem cell transplantation (HSCT), illucidating and analysing related factors in order to decrease the negative effects of HSCT on their emotion. Methods: Data were collected using a questionnaire to 53 HSCT patients and 50 families, who were older than 18 at tertiary-care institutions in Seoul, from January, 2000 to August, 2003. Results: There was a significant score difference in stress (t=-2.302, P<0.05). Correlation between stress and emotional status was statistically significant (r=0.486, P<0.01; r=0, P<0.05). Economical burden of cost had significant effects on stress of patients (F=4.194, P<0.05). The series of emotional status of patients without jobs were higher (T=-2.583, P<0.05). The emotional status of families were influenced by monthly income (F=4.036, P<0.05) and patients' diagnosis (F=3.088, P<0.05). Conclusion : These results suggest that the cares for families should be considered with great concern as well as the ones for patients. In addition, such factors as economical burden by medical cost, monthly income and job status should not be excluded in transplantation nursing plans.

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다문화 이주여성의 구강건강상태에 영향을 미치는 요인 (Factors influencing oral health status of immigrant women in multi-cultural families)

  • 이종화;최미숙;장영호
    • 한국치위생학회지
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    • 제17권1호
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    • pp.145-153
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    • 2017
  • Objectives: This paper aimed to contribute to better oral disease prevention and practice of health behavior for immigrant women in multi-cultural families, to define missing and filled permanent teeth index of immigrant women, data from the 6th Korea National Health and Nutrition Examination Survey from the Korea Centers for Disease Control and Prevention was used. Methods: For the immigrant women to be subjects, they needed to be born overseas, had acquired Korean citizenship as a married immigrant women, and the estimate of the number of subjects was 133,093 women. For analyzing data, SPSS 21statistical program was used. We used covariance analysis (ANCOVA) andgeneral linear models for finding the relation with the missing and filled permanent teeth index. The significance level was 0.05. Results: DMFT-index of immigrant women was 7.33 points. $R^2$ was 0.416; and increased with age, and $R^2$ was 0.126 points higher (p<0.01). In household income, 'lower' was 5.933 points lower than 'upper' (p<0.05), and in toothbrushing after lunch, 'yes' was 3.598 points lower than 'no' (p<0.01). In preventive treatment, 'yes' was 4.301 points lower than 'no' (p<0.05). Conclusions: The result of this paper is as follows: for maintaining oral health of immigrant women, we think that the government needs to develop an oral health policy and a customized education system suited to immigrant women for preventive management of dental disease in immigrant women. In addition, basic data will be provided for public dental health programs based on the result of the study.

범법 조현병 환자에서 한국형 성격장애척도를 이용한 성격장애 평가 (Use of the Korean Inventory of Interpersonal Problem Personality Disorder Scales to Assess Personality Disorder in a Criminal Schizophrenic Patient Sample)

  • 강지욱;이미지;권지현;지익성
    • 대한불안의학회지
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    • 제14권2호
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    • pp.120-126
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    • 2018
  • Objective : Psychopathy has been suggested as one of the important cause of violence in patients with schizophrenia. The purpose of this study was to evaluate the personality disorder in criminal schizophrenia. Methods : A total of 187 criminal schizophrenia participated in this study. All participants filled out the Korean Inventory of Interpersonal Problem Personality Disorder Scales (K-IIP-PD), Psychopathic Personality Inventory-Revised (PPI-R), Personality Assessment Inventory (PAI). Using the correlations between the scales, we investigated whether K-IIP-PD could be used to evaluate personality disorder in criminal schizophrenia. Moreover, participants were divided into two groups of psychopathic and nonpsychopathic schizophrenics, and scores of K-IIP-PD were compared between the two subgroups. Results : The overall correlation between the scales was very high. In particular, sum of 3 item scores (interprsonal sensitivity+interpersonal ambivalence+aggression) and aggression of K-IIP-PD were highly correlated with PPI-R and PAI. Total score of personality disorder scale and subscales were higher in psychopathic schizophrenic group compared to nonpsychopathic schizophrenic group. Conclusion : The K-IIP-PD could be used to assess the antisocial and aggressive nature of criminal schizophrenia. Further studies in various clinical groups including the general population are required.

전문대학 신입생의 의사결정역량, 대학생활적응, 대학생활만족도 정도 및 상관성 연구 (Levels and their Correlations of Decision-Making-Competency, Adjustment to College Life, Satisfaction to College Life in Freshmen)

  • 박미정;함영림;오두남
    • 한국콘텐츠학회논문지
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    • 제12권4호
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    • pp.327-337
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    • 2012
  • 본 연구는 전문대학 신입생의 의사결정역량, 대학생활적응, 대학생활만족도의 정도를 확인하고 이들 간의 관계를 규명하여 성공적인 대학생활을 위한 전략 모색 및 방안 마련의 기초자료를 제시하고자 수행되었다. 일개 전문대학에 재학 중인 1학년 남녀 신입생 325명을 편의추출하여 연구 대상으로 하였으며, 2009년 9월에서 10월까지 2개월간 구조화된 설문지를 통해 자료를 수집하여 SPSS 17.0으로 분석하였다. 연구결과 전문대 신입생이 지각한 의사결정역량의 정도는 $61.77{\pm}7.70$점, 대학생활적응은 $60.97{\pm}8.94$점, 대학생활만족도는 $57.97{\pm}10.80$점이었다. 여가활동유무는 대학생활적응(t=9.174, p<.001), 대학생활만족도(t=8.126, p<.001) 에서 통계적으로 유의한 차이를 보였고, 지각된 학업성취는 각 그룹 간 대학생활적응(F=18.673, p<.001), 대학생활만족도(F=26.000, p<.001)에서 모두 통계학적으로 유의한 차이를 나타내었다. 전문대 신입생의 의사결정역량과 대학생활적응(r=.159, p<.001), 의사결정역량과 대학생활만족도(r=.121, p<.05), 대학생활적응과 대학생활만족도(r=.543, p<.001)간의 관계는 통계적으로 유의한 양의 상관관계를 나타냈다. 이러한 결과는 대학 신입생을 위한 대학생활적응 프로그램 개발 및 재학생 중도 탈락을 예방하는 프로그램 개발에 활용될 수 있을 것이다.

Lactobacillus pentosus 발효에 의한 담쟁이덩굴 줄기 추출물의 항산화 및 세포보호 효과 (Antioxidant and Cellular Protective Effects of Parthenocissus tricuspidata Stem Extracts Fermented by Lactobacillus pentosus)

  • 박소현;성준섭;이건수;박영민;현송화;차미연;강희철;박수남
    • 대한화장품학회지
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    • 제43권3호
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    • pp.255-263
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    • 2017
  • 본 연구에서는 담쟁이덩굴 줄기 70% 에탄올 추출물과 발효균주 Lactobacillus pentosus를 이용하여 발효시킨 담쟁이덩굴 줄기 발효추출물에 대하여 항산화 및 세포보호 효과를 측정하였다. 1,1-Diphenyl-2-picrylhydrazyl(DPPH)를 이용한 자유라디칼 소거 활성($FSC_{50}$)은 담쟁이덩굴 줄기 추출물 및 발효추출물이 각각 42.3 및 $34.5{\mu}g/mL$로 발효 후의 라디칼 소거활성이 약 18.4% 더 높게 나타났다. Lumiol-의존성 화학발광법을 이용한 $Fe^{3+}-EDTA/H_2O_2$계에서의 총 항산화능($OSC_{50}$) 평가에서도 담쟁이덩굴 줄기 추출물과 발효추출물은 각각 2.6 및 $2.5{\mu}g/mL$로 발효 후가 약 4.2% 정도 더 높은 총 항산화능을 나타냈다. $^1O_2$로 유도된 적혈구 세포 손상에 있어서 추출물 및 발효추출물의 세포 보호 효과(${\tau}_{50}$)는 $50{\mu}g/mL$에서 각각 126.4 및 173.0 min을 나타내어 발효 후 세포 보호 효과가 약 34.0% 더 높게 나타났다. 발효추출물은 지용성 항산화제로 알려진 $(+)-{\alpha}$-tocopherol (43.4 min)보다도 3.9배 높은 세포 보호 활성을 보여주었다. 사람 섬유아세포인 Hs68을 대상으로 elastase 저해 활성을 조사하였다. Elastase 저해 활성($IC_{50}$)은 담쟁이덩굴 줄기 추출물과 발효추출물에서 각각 873.6 및 $687.8{\mu}g/mL$로 발효 후에 elastase 저해 활성이 약 21.3% 더 높은 것으로 나타났다. 이상의 결과들은 담쟁이덩굴 줄기 발효추출물이 항산화 작용과 더불어 주름개선 효과를 가지는 천연 화장품 소재로써 응용 가능성이 있음을 시사한다.

스켈링 실습실에 내원한 여고생의 구강건강 실태 조사 (A Study of the Actual Conditions of the Dental Health of High School Girls Visiting Scaling Practice Rooms)

  • 장계원;조평규;서은주;이미옥
    • 한국치위생학회지
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    • 제3권1호
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    • pp.13-24
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    • 2003
  • The researcher worked with a total of 158 high school girls visiting the scaling practice room at the department of dental hygiene in Jinju Health college from November 11, 2002 to December 4, 2002, having their teeth scaled, observing their teeth and interviewing them with the aid of questionnaires. The findings can be summarized as follows. 1. The survey on the understanding of dental health and the attitudes of the subjects shows the following results : "I have never learned how to brush teeth" (65.8%: 104 girls); "I brush my teeth twice a day" (57.0%: 90 girls) : "I brush my teeth for 2 minutes"(44.3%: 70 girls): "I brush my teeth vertically and horizontally" (53.2%: 84 girls): "( brush my teeth, gum and tongue" (462%: 73 girls): "I use one brush for two months" (40.5%: 64 girls); "I don't have any floss" (582%: 92 girls): "I have never had my teeth scaled" (84.2%: 133girls) : "Smoking is bad for the teeth" (77.8%: 123 girls): "Drinking is bad for the teeth" (48.7%: 77 girls): "I have ever visited dental clinics" (92.4%: 146 girls). 2. The study on part of the teeth most exposed to caries shows the following results : Mandibular right first molar(79.8%: 126 girls): Mandibular left first molar(77.5%: 124 girls), Mandibular left second molar(70.2%: 111 girls). Mandibular right second molar(65.7%: 104 girls). Maxillary left first molar(59.5%: 94 girls): Maxillary left second molar(59.5%: 94 girls): Maxillary right first molar(58.2%: 92 girls). Maxillary right second molar(50.7%: 80 girls) 3. The statistics on the subjects' caries show the following results: DMF rate: 943%: DMFT rate: 25.61%: DMFT index: 7.17 teeth : DT rate: 4651%: FT rate: 52.25%: MT rate: 124% 4. The survey on dental caries statistics, dental health, dental health behavior, and the subjects' attitudes shows the following results: The worse the subjects' dental health was(r=-327, p<.001), the more they visited dental clinics(r=.195, p<.05), the higher DMT rate, DMFT index were; The more the subjects visited dental clinics(r =.359, p<.001), the higher DT rate was; The worse the subjects teeth went(r=-.197, p<.05), the higher MT rate was. It is necessary that systematic and substantial dental health education for high school students should be carried out in regard to plaque control, fluoride application, diet control, pit & fissure sealant as a part of developing national health policies designed for the dental health of the teenagers.

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교정환자의 자아존중감과 구강건강영향지수(OHIP)에 영향을 미치는 요인 (Maincause of influencing oral health impact profile(OHIP) and self-esteem of orthodontic patients)

  • 박영남;이미라
    • 한국치위생학회지
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    • 제10권3호
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    • pp.513-522
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    • 2010
  • Objectives : This study aimed to determine self-esteem and oral health impact profile (OHIP) of orthodontic patients to get data necessary for the process of consultation, education, and treatment for those patients who hoped to get orthodontic therapy in order to see effects of orthodontic therapy on personal life in consideration of general characteristics of those patients under orthodontic therapy. methods : A self-administered questionnaire was used among 232 outpatients under orthodontic therapy from October to November 2009, obtaining the following results. Results : 1. As for general characteristics of respondents, those under 19 years of age constituted 46.6%; the unmarried comprised 85.8%; and students constituted 53.4%. 2. Most respondents were getting orthodontic therapy for beauty (41.8%) and dental health (40.5%). Family (54.3%) contributed to their decision to get orthodontic therapy; parents or siblings (62.5%) were bearing the treatment expenses. 3. Females were getting orthodontic therapy for an aesthetic purpose (50.3%), and male for the purpose of dental health (44.6%) (P<0.01). 4. OHIP was slightly higher among males ($4.10{\pm}0.61$) than among female ($4.00{\pm}0.78$), and was highest among those 19 years old and under ($4.17{\pm}0.67$); the older they were, the lower it was significantly (P<0.05). Most of them were earning 3 to 4 million won ($4.22{\pm}0.72$); the married ($4.05{\pm}0.74$) constituted higher percentage. As for occupation, students ($4.13{\pm}0.66$) comprised the highest percentage. 5. Self-esteem was higher among males ($3.83{\pm}0.47$) than among females ($3.80{\pm}0.50$), and was highest among those 25 to 29 years old ($3.92{\pm}0.46$). Most of them were earning more than 5 million won ($3.91{\pm}0.42$), which was statistically significant (P<0.01). The married ($3.91{\pm}0.54$) constituted higher percentage than the unmarried ($3.80{\pm}0.48$); office managers ($3.95{\pm}0.55$) comprised the highest percentage. 6. As for correlation between variables effecting OHIP of orthodontic patients, there was negative correlation in age (r=-0.225) and positive correlation in occupation (r=0.122). As for correlation between variables effecting self-esteem of orthodontic patients, there was negative correlation in occupation (r=-0.130) and positive correlation n income (0.126), while there was positive correlation (r=0.202) between OHIP and self-esteem of orthodontic patients. Conclusions : Younger orthodontic patients who were students showed higher OHIP, and professionals earning more showed higher self-esteem. Orthodontic patients with higher OHIP showed higher self-esteem. Therefore, it is necessary to develop a program based on OHIP and self-esteem in consulting and treating orthodontic patients; since it is considered that orthodontic therapy will improve appearance, enhance self-confidence, and have positive effects on interpersonal relationships and quality of living, researches are necessary on constant changes in psychological properties.

간호대학생의 셀프리더십, 공감능력과 우울이 대인관계능력에 미치는 영향 (Effects of Self-Leadership, Empathic Ability, and Depression on the Interpersonal Skills of Nursing Students)

  • 김미영;최윤숙
    • 대한통합의학회지
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    • 제11권3호
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    • pp.115-126
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    • 2023
  • Purpose : This study sought to determine the influence of nursing students' self-leadership, empathic ability, and depression on their interpersonal skills. Methods : This study applied a descriptive survey research design involving a self-report questionnaire. The participants were 315 nursing students in B city. Data were collected from April 27 to May 6, 2022. The data were analyzed using the percentage, mean, standard deviation, t-test, ANOVA, Scheffé test, Pearson's correlation coefficients, and multiple regression with IBM SPSS/WIN 23.0 program. Results : The participants' self-leadership score was 3.63±.65, their empathic ability score was 3.35±.40, their depression score was .84±.50, and their interpersonal skills score was 3.64±.80. Among the sub-categories, others' temperament scored the highest at 3.70±.86, followed by communication at 3.67±.86 and promoting relationships at 3.53±.86. Interpersonal skills were positively correlated with both self-leadership (r=.48, p<.001) and empathic ability (r=.33, p<.001). Self-leadership was positively correlated with empathic ability (r=.17, p<.05), but, negatively correlated with depression (r=.27, p<.001). The multiple regression analysis revealed, that the factors with the most significant effect on promoting relationships were, in descending order, self-leadership (β=.49, p<.001), empathic ability (β=.19, p<.001), and gender (β=.10, p=.033); the factors affecting others' temperament were, in descending order, self-leadership (β=.37, p<.001), empathic ability (β=.30, p<.001), severe depression (β=.14, p=.008), gender (β=.13, p=.010), and grade (β=-.13, p=.037); while the factors affecting communication were, in descending order, self-leadership (β=.41, p<.001), empathic ability (β=.23, p<.001), and gender (β=.11, p=.035). Moreover, the explanatory power of promoting relationships scored the highest at 31 %, followed by others' temperament at 27 % and communication at 26 %. Conclusion : The results of this study reveal the factors that influence the interpersonal skills of nursing students. To increase the interpersonal skills of nursing students, it is necessary to develop and apply regular curricula and programs designed to strengthen their self-leadership and empathic ability and to reduce their depression through reflecting differences between genders and grades.

포천시 초등학생의 주관적 구강건강인식 및 구강보건 행태와 우식경험영구치지수와의 관련성 (An analysis of the associated factors which influence DMFT index of the primary school children's in Pocheon city)

  • 김영남;송윤신;최은정;김영수;최은미
    • 한국치위생학회지
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    • 제11권1호
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    • pp.113-126
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    • 2011
  • Objectives : We supposed that identifying the influencing factors on DMFT index in the primary school children in Pocheon be indispensible for the primary school children's oral health program establishment in Pocheon. So, to prepare the basic materials for the primary school children's oral health program establishment in Pocheon, we analyzed the associated factors which could have an influence on the primary school children's DMFT index in Pocheon. Methods : We selected 3,676 primary school children in Pocheon, whose age were from 6 to 11, and surveyed those children by a questionnaire and the oral examination based on WHO's oral health survey method. Data were analyzed with a $x^2$-test and multiple regression analysis using SPSS $15.0^{(R)}$. Results : The results of oral survey in the primary school children in Pocheon revealed as follows: DMFT index, National Health Oral health survey of 2006 people nationwide in the results when compared to younger grade children and older grade in the low and the higher. Subjective oral health awareness, high of viscosity junk food snacks, fruit, gender, dental visits and humidity, oral health education classes, including the variable of attitude was 6(p<0.05). Their higher awareness of dental health, oral health education classes ever the more positive attitude to DMFT index was statistically significant(p<0.05). Solid in the habit of eating junk food snacks to the students of a liquid relative to student intake was higher DMFT index indices(p<0.05). Conclusions : We could reason that one's oral health recognition and behavior should have a relationship with his(her) DMFT index.

Effect of Ionic Copper Toxicity on the Growth of Green Alga, Selenastrum capricornutum

  • Kim, Mi-Kyung;Ralph E. H. Smith
    • Journal of Microbiology and Biotechnology
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    • 제11권2호
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    • pp.211-216
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    • 2001
  • The growth of Selenastrum capricornutum in culture was investigated as a function of ionic copper concentrations to verify the toxicity and physiological variation. In a $Cu^{++}$ excess culture (E: $Cu^{++}$ of $130{\mu}g/l$), the growth rate (K)(0.32) was lower than that of the control culture (C: $Cu^{++}$ of $0.065{\mu}g/l$) (0.61) after 8 days and the exponential growth rate ($R_E$) was also found to be lower in culture E (1.1) than culture C (2.9). On the contrary, the K of S. capricornutum in trace $Cu^{++}$ culture ($T_1$ and $T_2$, 0.72) after 6 days tended to be more increased than culture C (0.68). From 8 to 14 days of culture, the amounts of chlorophyllls a and b were increased in culture C (chlorophyll a, $106->126{\mu}g/g$ dry wt; chlorophyll b, $158->208{\mu}g/g$ dry wt; chlorophyll b were decreased in culture E (chlorophyll a, $309->235{\mu}g/g$ dry wt; chlorophyll b, $405->352{\mu}g/g$ dry wt). The amounts of chlorophylls in ionic copper trace culture ($T_1$ and $T_2$) [(chl a/b) of $T_1$: $384/620\;{\mu}g/g$ dry wt; (chl a/b) of $T^2$:$320/467{\mu}g/g$ dry wt] were increased more than the culture C($260/387{\mu}g/g$ dry wt). Howeveer, when photosynthetic rates were normalized to the dry weight of algae, the control culture continued to showed higher values than the treated culture ($T_1$). An appropriate amount of ionic copper ($T_1:\;26\;{\mu}g/l$) stimulated the grwoth of S. capricornutum than the ionic copper content of $13\;{\mu}g/l$ ($T_2$), while the excess amount of ionic copper ($130\;{\mu}g/l$) resulted in the highest toxicity to the growth of S. capricornutum.

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