• 디지털융복합연구
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• 제14권7호
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• pp.269-277
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• 2016

본 연구에서는 한국인의 대표성이 있는 자료인 국민건강영양조사 자료를 이용하여 대사증후군 및 그 구성요소들과 골 관절염의 상관관계에 관하여 조사하였다. 여성의 경우, 골 관절염군에서 대사증후군의 유병률이 증가하였으며, 여성에서 대사증후군의 구성요소들, 예를 들어 허리둘레, 중성지질, 수축기 혈압, HDL-콜레스테롤과 골 관절염의 유병률은 통계적으로 유의한 상관관계가 있음이 증명되었다. 또한 생활습관변수 및 사회경제적 변수로 보정하였을 때 대사증후군의 위험요소의 수가 증가할수록 골 관절염의 위험도는 더욱 커지는 경향을 보였다 (p<0.0001). 따라서 이번 연구에서 제시되어진 바와 같이 대사증후군은 골 관절염의 새로운 위험인자로서 인식되어야 하며 골 관절염의 예방과 치료 시 대사증후군 역시 고려되어야 할 요소의 하나로 사료된다.

• Nutrition Research and Practice
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• 제15권3호
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• pp.329-345
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• 2021

BACKGROUD/OBJECTIVES: Evidence has suggested an association between serum vitamin D and metabolic syndrome (MetS), but prospective studies are very limited. The objective was to assess the dose-response association between serum vitamin D concentration and MetS risk using a systematic review and meta-analysis of updated observational studies. MATERIALS/METHODS: Using MEDLINE, PubMed, and Embase, a systematic literature search was conducted through February 2020 and the references of relevant articles were reviewed. A random-effects model was used to estimate the summary odds ratio/relative risk and 95% confidence interval (CI). Heterogeneity among studies was evaluated with I² statistic. In total, 23 observational studies (19 cross-sectional studies, and four cohort studies) were included in the meta-analysis. RESULTS: The pooled estimates (95% CI) for MetS per 25-nmol/L increment in serum vitamin D concentration were 0.80 (95% CI, 0.76-0.84; I² = 53.5) in cross-sectional studies, and 0.85 (95% CI, 0.72-0.98; I² = 85.8) in cohort studies. Similar results were observed, irrespectively of age of study population, study location, MetS criteria, and adjustment factors. There was no publication bias for the dose-response meta-analysis of serum vitamin D concentrations and MetS. CONCLUSIONS: Dose-response meta-analysis demonstrated that a 25-nmol/L increment in the serum vitamin D concentration was associated with 20% and 15% lower risks of MetS in cross-sectional studies and cohort studies, respectively.

• Nutrition Research and Practice
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• 제15권1호
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• pp.80-94
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• 2021

BACKGROUND/OBJECTIVES: Recent studies have reported chocolate consumption has beneficial effects on blood pressure, obesity, and dyslipidemia, which are components of metabolic syndrome (MetS). However, evidence regarding these relationships in Asia is limited. The aim of this study was to investigate relations between chocolate consumption and MetS in Korea. SUBJECTS/METHODS: Study subjects were 6,982 adults aged 19-64 years free of major chronic diseases that participated in the 2014-2016 Korea National Health and Nutrition Examination Survey. Information on chocolate consumption was obtained using food frequency questionnaires. For primary analysis, subjects were divided into two groups: non-consumer (n = 3,741, 53.6%); consumer (n = 3,241, 46.4%). In order to investigate dose-response effects on MetS, chocolate consumers were divided into quartiles based on amounts consumed: Q1 (n = 789, 24.3%); Q2 (n = 837, 25.8%); Q3 (n = 863, 26.6%); Q4 (n = 752, 23.2%) in second analysis. RESULTS: Chocolate consumers; 1) were more physically active(P < 0.0001); 2) less likely to smoke(P < 0.0001); 3) paid more attention to food nutrition labels (P < 0.0001), and 4) had healthier dietary patterns, that is, they consumed vegetables, fruits, and dairy products more frequently(P < 0.0001) than non-consumers. Furthermore, chocolate consumers had a 30% lower risk of MetS (odds ratio, 0.70; 95% confidence interval, 0.58-0.86; P = 0.0005). However, dose-response effects between chocolate intake and MetS was not found by secondary analysis after excluding non-consumers. CONCLUSIONS: In conclusion, chocolate consumers had healthier lifestyles and dietary patterns and a lower prevalence of MetS than non-consumers, as determined by our primary analysis. Although dose-response effects were not found to be significant among chocolate consumers during secondary analysis, the patterns were partially similar. This cross-sectional finding shows chocolate consumption does not increase the risk of MetS. The prospective studies and intervention trials in Korea are needed to confirm this cross-sectional finding.

• The Korean journal of internal medicine
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• 제39권2호
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• pp.272-282
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• 2024

Background/Aims: Metabolic syndrome (MetS) raises the risk of cardiovascular disease and type 2 diabetes. An awareness of MetS is vital for early detection and proactive management, which can mitigate the risks associated with MetS. Therefore, our study aimed to investigate the level of awareness of MetS among the Korean population. Methods: We conducted a nationwide survey between January and February 2023 among a representative sample of the Korean population using an online survey. Information regarding the awareness of MetS and its risk, the importance of lifestyle modification, and health behavior were collected. The question about the awareness of MetS was "How much do you think you know about MetS?" and there were five answers: 1) I know very well, 2) I know well, 3) I know a little, 4) I do not know, and 5) I have no idea. The high-awareness group was defined as those who answered that they knew very well or well. Results: Among 1,000 participants (mean age, 45.7 ± 13.2 yr), 29% were unaware of MetS, and only 20.8% had high awareness. The high-awareness group was significantly more knowledgeable about lifestyle modifications and demonstrated better health behaviors. After adjustment for possible confounding factors, younger age, low household income, and absence of comorbidity were independently associated with a lack of awareness regarding MetS. Conclusions: The high-awareness group showed greater knowledge of the importance of lifestyle modifications and better health behaviors regarding MetS. The findings highlight the need for improved public education and awareness programs regarding MetS.

• 중환자간호학회지
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• 제16권2호
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• pp.67-80
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• 2023

Purpose : The 2020 Dietary Guidelines Advisory Committee specifically noted that meal frequency is associated with risks for cardiovascular disease, type 2 diabetes, and all-cause mortality, although the current evidence on meal frequency is conflicting. As meal frequency itself is affected by various factors, the aim of the study was not only to examine its relationships with cardiometabolic risk but also to identify the mediating effects of dietary quality. Methods : This study used a descriptive correlational design. In all 8,141 healthy adults participated in the study. Measurements included meal frequency, cardiometabolic risk, and diet quality. Data were analyzed using descriptive statistics, Pearson's correlation coefficient analysis, and process macro bootstrapping model 4. Results : The meal frequency was 3.52±0.61 times per day, the risk of cardiovascular metabolic diseases was 0.01±0.61 points, and the diet quality was 62.08±13.87 points. In mediation analysis, the effect of meal frequency on cardiometabolic risk score was completely mediated by diet quality. Conclusion : Improved diet quality in healthy adults should be considered when designing meal frequency interventions aimed at reducing their cardiometabolic risk, as the effect of meal frequency support on cardiometabolic risk was found to be mediated by diet quality.

• 한국융합학회논문지
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• 제7권3호
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• pp.99-109
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• 2016

본 연구는 대사증후군의 위험요인과의 관계를 분석함을 통해 대사증후군 및 심혈관 질환의 효과적인 예방 관리 체계 수립을 위한 근거자료를 제시하고, 대사증후군 환자 교육과 직장인의 만성질환에 관한 중요한 기초자료를 제공하고자 우리나라 직장인의 건강검진 결과를 통하여 건강관련 행위, 흡연 음주 등과 운동이 대사증후군에 미치는 영향력을 알아보고자 하였다. 연구의 조사대상은 서울에 기반한 전문 건강검진센터에서 직장의료보험으로 검진을 받은 직장인 291명으로 하였다. 본 연구의 자료는 직장인 건강검진 내용을 바탕으로 하였다.연구방법으로는 SPSS/Win Program ver 20.0을 이용하여 분석하였으며, 독립변수와 종속변수와의 관계를 분석하기 위하여 F-test 검증 및 ANOVA test를 실시하였으며, 연관성의 검증을 위해서는 $x^2$(Chi-square) 검증을 실시하였다. 연구결과는 직장인 291명 중 대사증후군 유병률이 19.2%로 나타났고, 흡연행태로 인한 대사증후군 유병률의 비흡연 그룹은 12.7%, 과거 흡연 그룹 중에서 가볍게 흡연했던 그룹은 25.0% 중흡연 그룹은 25.9%, 현재 흡연 그룹 중에서 경흡연 그룹은 29.7% 중흡연 그룹 26.7%로 분석되었다. 결과적으로, 본 연구는 직장인의 흡연과 음주 생활형태가 직장인의 대사증후군 유병률과 밀접한 융합적 관련성이 있음을 시사하고 있다.

• Journal of Acupuncture Research
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• 제22권3호
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• pp.77-92
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• 2005

가시오가피약침(五加皮藥鍼)이 대사증후군(代謝症候群)에 미치는 영향을 알아보기 위하여 ICR mouse에 고지방식이로 비만과 대사증후군(代謝症候群)을 유도하면서 신유(腎兪)(BL23)에 상응하는 부위에 일정한 방법으로 가시오가피약침(五加皮藥鍼)후 체중, 식이효율, 혈중 glucose, insulin level, insulin resistance, 경구내당능, 혈압, 혈중지질의 변화, 지방조직의 중량과 면적, 조직학적 변화와 GLUT-4 mRNA 및 UCP-1 mRNA의 발현을 관찰하여 유의한 결과를 얻었다. 1. 가시오가피약침(五加皮藥鍼)은 체중의 증가와 식이효율의 상승을 억제하였다. 2. 가시오가피약침(五加皮藥鍼)은 혈중 glucose, insulin level 및 insulin resistance의 상승을 억제하고, 경 구내당능을 개선시켰다. 3. 가시오가피약침(五加皮藥鍼)은 혈압의 상승을 억제하였다. 4. 가시오가피약침(五加皮藥鍼)은 혈중지질의 이상을 개선시켰다. 5. 가시오가피약침(五加皮藥鍼)은 WAT, BAT 및 liver 중량의 증가를 억제하였고, WAT와 BAT의 면적과 직경의 증가를 억제하였다. 6. 가시오가피약침(五加皮藥鍼)은 GLUT-4 mRNA 및 UCP-1 mRNA 발현의 증가를 억제하였다.

• 한국산업간호협회지
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• 제17권4호
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• pp.43-43
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• 2010

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 2004년도 제56차 추계 학술대회 연제집
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• pp.44.1-44.1
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• 2004

• 사상체질의학회지
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• 제25권3호
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• pp.180-194
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• 2013

Objectives Impaired lung function(ILF) and sasang constitution(SC) is associated with metabolic syndrome(MS). However, the relationship between ILF and SC is unclear. So, we assessed the relationship between ILF and MS according to SC, and examined whether SC is an independent risk factor for ILF. Methods This study included 1,148 subjects 40years and older who were performed the health examination at Kyung Hee University Hospital in Korea between December 2011 and February 2013. We defined ILF if FVC or $FEV_1$ value were less than lower limit of normal(LLN), and classified ventilatory patterns as obstructive pattern and restrictive pattern. MS was assessed according to AHA/NHLBI criteria. We used multivariate logistic regression to analyze the association of ILF with MS respective to SC types, and to identify the risk of SC types for ILF. Odds ratio(OR) was calculated by adjusting for age, sex, smoking status, drinking, physical activity, and BMI. Results In whole subjects, ILF was associated with MS [OR (95% CI), 1.69 (1.24-2.31) for FVC, 1.67 (1.20-2.33) for $FEV_1$]. And in Taeeum type(TE type) and Soeum type(SE type), ILF was associated with MS [1.63 (1.10-2.42) for FVC, 1.48 (1.01-2.24) for $FEV_1$ in TE type; 6.93 (1.14-42.00) for FVC in SE type], while in Soyang type(SY type), it wasn't. The restrictive pattern was associated with MS in TE type and SE type, while in SY type, it wasn't. Furthermore, TE type and SY type had more risk for ILF than SE type [1.71 (1.12-2.59) for SY type, 1.95 (1.23-3.08) for TE type in FVC; 2.06 (1.26-3.36) for TE type in $FEV_1$; 1.85 (1.21-2.85) for SY type, 2.17 (1.35-3.49) for TE type in Restrictive pattern]. Conclusions These results show that SC is an independent risk factor for ILF, especially TE type and SY type than SE type, and the prevalence of MS is an independent risk factor for ILF in TE type.