• Journal of Acupuncture Research
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• v.21 no.6
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• pp.111-120
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• 2004

Objective : Assuming that the characteristic of meridian system has been similar to this of electric potentials in human body and that measurements of electric potential at well(井穴) and sea (合穴) points in branches of the twelve meridians(WSBTM) will be representative of measurements of the twelve meridians, to measure the electric potentials of 13 patients with Facial Hemiparalysis (구안와사<口眼蝸斜>, FH), to find out the characteristic of meridian system in patients with AK. Methods : Electric potentials of well and sea points in the meridians in twenty one patients with the pain in the lion diagnosed as FH were repeatedly measured by physiograph(PowerLab). Measurements of those electrical potentials were analyzed by factor analysis. Results : The electric potentials of WSBTM at the left side were divided into five factors. On the other hand those at the right side Were divided into four factors. Conclusions : In conclusion, their electrical potentials at the left and right side were each other five and four factors. Thus electrical potentials of well and sea points might be the representative meridian to show their characteristics.

• Korean Journal of Acupuncture
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• v.32 no.3
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• pp.124-129
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• 2015

Objectives : The purpose of this study is to understand truncus area conception to be explained in the pyobon and geungyul (Root-Stem and Origin-End relationships; PG) of meridian theory as to do the macro organic spatial conception in bio-mechanic system for human body. Methods : The extremity areas and truncus area to be explained in PG theories were classified spatially, and the reason was discussed that human body was classified as the extremities and truncus areas for the people of old times. It was considered the structural characteristics, exercise species and movement characteristics of truncus area in human body also. Results : The truncus area were made of cranium, vertebrae, sternum, ribs, clavicle, scapula, sacrum and the hipbone. It was the hollow structure and classified as cranial cavity, pleural cavity(thoracic cavity) and pelvic cavity. These cavities had mutually organic relationships, and because of cavity structures in the truncus and full structures in extremities would act in different direction about gravity with each other for movements. So it would be estimated that the old peoples had to need to separate the truncus and the extremities. Conclusions : In this study, the truncus area and the extremity areas in the PG of meridian theory could be recognized as the spatial conception of bio-mechanic system in human body. Although this study was the theoretical study not to be proven, it will be used to understand for the meridian theory as basic reference for spatial conception and bio-mechanic system.

• Biomolecules & Therapeutics
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• v.24 no.3
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• pp.328-337
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• 2016

We examined whether wogonin (WO) improved hippocampal neuronal activity, behavioral alterations and cognitive impairment, in rats induced by administration of trimethyltin (TMT), an organotin compound that is neurotoxic to these animals. The ability of WO to improve cognitive efficacy in the TMT-induced neurodegenerative rats was investigated using a passive avoidance test, and the Morris water maze test, and using immunohistochemistry to detect components of the acetylcholinergic system, brain-derived neurotrophic factor (BDNF), and cAMP-response element-binding protein (CREB) expression. Rats injected with TMT showed impairments in learning and memory and daily administration of WO improved memory function, and reduced aggressive behavior. Administration of WO significantly alleviated the TMT-induced loss of cholinergic immunoreactivity and restored the hippocampal expression levels of BDNF and CREB proteins and their encoding mRNAs to normal levels. These findings suggest that WO might be useful as a new therapy for treatment of various neurodegenerative diseases.

• Korean Journal of Acupuncture
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• v.32 no.4
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• pp.190-198
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• 2015

Objectives : Through comparison between Mawangdui Silk Manuscripts and Huangdi's Internal Classic, this study aimed to put an emphasis on clinical significance of Yin-yang theory in Meridians. Methods : We investigated the documents recorded in Yin Yang Shi Yi Mai Jiu Jing, Zu Bi Shi Yi Mai Jiu Jing and Miraculous Pivot to compare of the character of meridian names. Results : In the naming of meridians, three yin and three yang were accepted earlier than Viscera and Bowels. Three yin and three yang play important role in relation with division of a human body. Conclusions : It is necessary to focus on the importance of Yin-yang theory in meridian system.

• Korean Journal of Acupuncture
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• v.37 no.4
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• pp.245-252
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• 2020

Objectives : The objective of this study was to examine the acupoint location of Kyoshin (KI8) from classic literatures. Methods : A review of KI8 location along the meridian route from 18 classics of acupuncture and moxibustion - 『Huangdineijing·Lingshu』, 『Huangdimingtangjingjixiao』, 『Zhenjiujiayijing』, 『Huangdineijingtaisu』, 『Huangdimingtangjiujing』, 『Beijiqianjinyaofang』, 『Waitaimiyaofang』, 『Ishimpo』, 『Taipingshenghuifang』, 『Tongrenshuxuezhenjiutujing』, 『Shengjizonglu』, 『Zhenjiuzishengjing』, 『Shisijingfahui』, 『Shenyingjing』, 『Zhenjiujuying』, 『Yixuerumen』, 『Zhenjiudacheng』, and 『Yizongjinjian』 - was performed. Then, KI7 location on classics and current standard KI8 location were compared. Results : Based on modern standard acupoint location system, the acupoint of KI8 is located on the medial aspect of the leg, in the depression posterior to the medial border of the tibia and it is on the route of spleen meridian. But no classics of acupuncture and moxibustion said KI8 was located on the route of spleen meridian. In addition, KI8 location on classics was largely described as being located in front of KI7, but only in 『Yizongjinjian』 was it written that KI8 was located posterior to KI7. Conclusions : Through a classic literature review, it is possible to explain that KI8 is located posterior to spleen meridian. The acupoint of KI8 seems to be located between medial border of flexor pollicis longus and flexor digitorum longus based on anatomical location.

• 대한상한금궤의학회지
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• v.5 no.1
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• pp.75-84
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• 2013

Objective : This case report evaluated the effect of Saengkangsasim-tang(生薑瀉心湯) on allergic rhinitis. Methods : Two different patients of allergic rhinitis were treated with Saengkangsasim-tang (生薑瀉心湯) in accordance with diagnostic system based on Shanghanlun(傷寒論) six meridian patterns and provisions. Results : After a series of Saengkangsasim-tang treatments, the symptoms of allergic rhinitis patients improved in 2 cases. Conclusions : According to diagnostic system based on Shanghanlun(傷寒論) six meridian patterns and provisions, this case study shows that Saengkangsasim-tang is effective on allergic rhinitis. However further clinical studies in depth are needed.

• 대한상한금궤의학회지
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• v.6 no.1
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• pp.89-96
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• 2014

Objective : This case report evaluated the effect of Soseungki-tang(小承氣湯) on mood disorder. Methods : A patient of mood disorder was treated with Soseungki-tang(小承氣湯) in accordance with Shanghanlun(傷寒論) six meridian patterns diagnostic system. Results : After a series of Soseungki-tang treatment, the symptoms of mood disorder patient improved. Conclusions : According to Shanghanlun(傷寒論) six meridian patterns diagnostic system, this case study shows that Soseungki-tang is effective on mood disorder. However further clinical studies in depth are needed.

• 대한상한금궤의학회지
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• v.6 no.1
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• pp.55-62
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• 2014

Objective : This case report show the effect of Yonggyechulgam-tang on Panic disorder. Methods : The patient was diagnosed Panic disorder based on DSM-5. According to Shanghanlun six meridian patterns diagnostic system, the patient treated with Yonggyechulgam-tang for 4 months. The level of panic disorder was evaluated by VAS and BAI. Results : After the treatment, VAS and BAI decreased $10{\rightarrow}2$, $42{\rightarrow}4$ each. Conclusions : Yonggyechulgam-tang improved the symptoms of Panic disorder on this study. Although Yonggyechulgam-tang is not an usual treatment for Panic disorder, we could prescribe the medicine due to Shanghanlun six meridian patterns diagnostic system.

• Korean Journal of Acupuncture
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• v.27 no.4
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• pp.49-57
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• 2010

Objectives : The aim of this study is evaluation for significance of skin meridian-acupoints energy measurement system, and is verification of principle to measure the bio-ion charge on acupoints. Methods : To check a correlation between the MEP(Meridian Energy Potential) and bio-electric charge condition, ten acupoints(left/right BL meridian : BL13, BL15, BL18, BL20, BL23) were chosen. Based on basic theory concerning the upward trend of the bio-electric charge by cupping therapy, we measured MEP change before and after 600mmHg(80kPa) Negative pressure stimulation using cupping. Results : We could identify the correlation between MEP and the condition of bio-electric charge in acupoints. Also, we checked the balance or imbalance of left/right the MEP and unusual cases. Conclusions : We confirmed significance of proposed principle and meridian energy measurement system.

• Journal of Acupuncture Research
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• v.20 no.4
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• pp.114-133
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• 2003

Objective : The meridian theory in oriental medicine explains that Sp9(Yinlingquan) has been considered very important for gynecological disorders, spleen and stomach disorders, and water metabolic disorders. Functional MRI is the best method of showing the evidences of the effect of the Electro-acupuncture treatment through scientific methods. On this supposition, Electro-acupuncture stimulation on Sp9(Yinlingquan) was carried out on six healthy volunteers, using the gradient echo sequence with the 3.0T whole-body MRI system(ISOL). Methods : Electro-acupuncture stimulation on Sp9(Yinlingquan), the experiment was carried out on six healthy volunteers, using the gradient echo sequence with the 3.0T whole-body MRI system(ISOL). After the needle insertion on right Sp9(Yinlingquan), 2Hz of electric stimulation was given for 30 seconds, repeated five times, with 30 seconds' intervals. The Image analysis including motion correction, talairach transformation, and smoothing was done using SPM99. Results : The electro-acupuncture stimulation on Sp9(Yinlingquan) activates Brodmann Area 13, 19, 22, 39, 40, 47 which may be the central pathways of the electro-acupuncture stimulation on Sp9(Yinlingquan). We also hypothesize that those brain areas may be directly or indirectly related with the mechanism of the effect of electro-acupuncture stimulation on Sp9(Yinlingquan).