• 한국콘텐츠학회논문지
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• 제15권5호
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• pp.254-264
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• 2015

이 연구에서는 갱년기여성의 생활스트레스가 생활만족도와 우울에 미치는 영향을 분석해보았다. 연구대상자들은 대전광역시와 충청남도에 거주하는 425명의 갱년기 여성들이고, 자료는 SPSS 19.0을 통해 기술통계, t-test, ANOVA, Scheffe's test, 상관분석, 그리고 다중회귀분석을 통해 분석되었다. 자료의 분석결과 갱년기 여성의 생활스트레스는 결혼상태, 월수입, 월경상태 등의 수준에 따라 다르게 나타났다. 아울러 갱년기 여성의 생활스트레스와 생활만족도 간에는 유의미한 정적 관계가 나타났다. 반면에 갱년기 여성은 생활스트레스가 우울에는 부적 영향을 미치는 유의한 상관관계가 있는 것으로 나타났다. 이러한 연구결과를 통해 갱년기 여성의 생활만족도를 향상시키고 우울을 낮추기 위한 실천적 방안으로 사회적 지지와 상담 및 통합프로그램 제공과 함께 노년기 준비를 위한 역량강화 프로그램의 제공을 제언하고자 한다.

• 한국생활과학회지
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• 제23권6호
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• pp.1105-1126
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• 2014

The purpose of this study was to explore the factors related to depression of married baby-boomer female by employment status. Data for this study was based on a convenience sample of 499 married female baby-boomer who have residence in Busan and Gyeongnam province. The prevalence rate of depression symptoms was 21.4%. The employment status made differences on the factors related to depression of married female baby boomers. Depressive symptoms were significantly associated with attitudes toward menopause, menopausal symptoms and marital satisfaction for both baby-boomer female with and without a job. While monthly household income, participation in voluntary associations and satisfaction with children were significantly related to depression symptoms of baby-boomer female without employment, perimenopausal stage, perceived size of social network was important factors for the depression of married female baby boomers with a job.

• 기본간호학회지
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• 제22권3호
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• pp.258-267
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• 2015

Purpose: The purpose of study was to compare depression, marital intimacy, sexual function and quality of life between a group of sexually active women and a group of women who were sexually inactive. All of the women were post-menopausal married women. Methods: Post-menopausal married women (n=395) of 40 to 59 years old participated in the study. Data were collected through self-report questionnaires which included items on general characteristics, and tools on depression (CES-D), marital intimacy (MIQ), sexual function (FSFI), and quality of life. Data were analyzed using descriptive statistics, t-test, $X^2-test$, ANCOVA, and Pearson correlation coefficients. Results: About 42% of the participants were identified as sexually inactive. Marital intimacy, sexual function, and quality of life in the sexually active group were significantly higher than the inactive group (F=17.12, p<.001; F=36.86, p<.001; F=16.78, p<.001). Depression scores in the sexually active group were significantly lower than in the inactive group (F=14.64, p<.001). Also, there was a significant relationship of depression, marital intimacy, and sexual function to quality of life in both groups. Conclusion: The results of this study indicate that health professionals need to counsel and provide a psychosexual approach especially when caring for post-menopausal married women who are sexual inactive.

• 융합정보논문지
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• 제10권3호
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• pp.31-37
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• 2020

본 연구는 중년여성의 갱년기증상과 자아존중감이 우울에 영향을 미치는 영향요인을 파악하기 위해 시도되었다. 본 연구는 2개 지역 D 와 S 지역에 거주하는 중년여성 대상으로 연구의 취지, 목적, 과정에 설명을 하고 동의한 125명을 대상으로 하였다. 자료는 SPSS 21.0 을 이용하였고, 빈도분석, 분산분석, t검증, 상관분석, 희귀분석으로 실시하였다. 자료수집은 2019년 1월부터 2019년 2월까지 하였다. 본 연구결과는 아래와 같으며, 중년여성들의 일반적 특성에 따른 우울의 차이는 주관적 경제상태와 주관적 건강상태에서 유의미한 차이를 보였다. 우울에 영향을 미치는 변수는 갱년기증상(β=.409, p<.001), 자아존중감(β=-.368, p<.001), 건강상태(β=-.094 p=.174), 경제상태(β=.067 p=.353)순으로 확인되었다. 우울은 개인마다 차이가 있으므로 중년여성의 갱년기증상과 우울정도를 확인하여 갱년기를 자연스러운 인생의 전환기로 받아들이고 갱년기 여성의 사회정책, 간호정책개발에 활용되어야 할 것이다.

• 생약학회지
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• 제51권4호
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• pp.310-316
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• 2020

Kyung-Ok-Go (KOK) is a traditional prescription used for debilitating natural aging and post-illness debilitation. KOK has been used in a variety of ways because it strengthens immunity, prevents illness, and helps recovery in case of illness. In particular, recent research has revealed that KOK helps improve memory and cognition. Therefore, in this study, we investigated whether KOK was effective in improving memory decline and depression-state observed during menopause. In the present study, we employed ovariectomized mouse as an animal model for measuring menopausal syndrome. The administration of KOK for 8 weeks, the object recognition memory and working memory were improved in novel object recognition test and Y-maze test. And in the forced swimming test, the immobility time were decreased. Additionally, the expression level of mature brain derived neurotropic factor (mBDNF) was increased by KOK administration in ovariectomized mouse hippocampus. These results suggested that KOK could improve cognitive decline and depression during menopausal period, and it might be come from enhancing expression level of mBDNF in hippocampus.

• 생물정신의학
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• 제16권4호
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• pp.229-237
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• 2009

Recent Korean statistics show that a Korean woman can now expect to live until her mid-80s, which implies living at least one-third of her life after menopause. The menopausal transition is typically marked by intense hormonal fluctuations, accompanied by sleep disturbance, vasomotor symptoms(e.g., hot flashes, night sweats), increased risk for osteoporosis, cardiovascular disease, and developing depression as well as mood disturbances. These symptoms can affect a woman's quality of life negatively. Therefore, a comprehensive understanding of the accurate detection and appropriate treatment of various menopause-related symptoms including depression in the menopausal transitions and postmenopause is mandatory. This review primarily focused on the current knowledge about the treatment of menopause-related depression.

• 동의신경정신과학회지
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• 제20권4호
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• pp.149-159
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• 2009

Objectives : This study was performed to report the effect of Korean traditional treatments for Hwa-Byung with menopausal symptoms. Methods : In this case, a 48 years old female patient has been suffered by Hwa-Byung with menopausal symptoms for 3 years old. We treated the patient with Korean traditional treatments (acupuncture, herb-medication and aroma theraphy), mindfulness and Korean traditional psychotherapy. The effects of treatment were measured by Beck Depression Inventory(BDI), Zung Depression Rating Scale(SDS), Kupperman Index(KI), Menopause Rating Scale(MRS). Results : After treatment, the chief complaints and accompanying symptoms were subsided and improved. And BDI, SDS, KI and MRS score were decreased. Conclusions : According to this study, the Korean traditional treatment such as acupuncture, herb-medication is effective for the cure of Hwa-Byung with menopausal symptoms.

• 생물정신의학
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• 제12권2호
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• pp.173-180
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• 2005

Purpose:We investigated the effect of menopausal duration on cognitive function using adjunctive hormone replacement therapy(HRT) in postmenopausal women with depression. Method:Twelve postmenopausal women with depressive disorder were enrolled. Six patients having menopausal duration of less than 3 years was assigned to the short duration group and six patients of more than 3 years to the long duration group. Each patient was treated with conjugated equine estrogen(1.25mg) plus medroxyprogesterone(5mg) for 8 weeks. Cognitive performance was measured by the Verbal Memory Test, Visual Memory Test, Trail Making Test, Digit Symbol Test, and Attention Shift Test. The Beck Depression Inventory was used for evaluation of depressed mood. The reproductive hormone levels were also measured. Results:The long duration group showed the lower performance only in Trail Making Test B compared with the short duration group at baseline. After 8 weeks, the long duration group performed significantly better in the Trail Making Test B compared with the short duration group. The differences in change of depressive mood and gonadal hormone level between two groups were not significant. Conclusion:Menopausal duration before HRT may influence the effect of estrogen on cognition in some cognitive domains. This might be related with estrogen receptor hypersensitivity which induced by the longer estrogen deficiency.

• Journal of Menopausal Medicine
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• 제24권3호
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• pp.183-187
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• 2018

Objectives: The present mini review aimed to summarize the existing knowledge regarding the beneficial and adverse effects of raloxifene in menopausal women. Methods: This study is a review of relevant publications about the effects of raloxifene on sleep disorder, depression, venous thromboembolism, the plasma concentration of lipoprotein, breast cancer, and cognitive function among menopausal women. Results: Raloxifene showed no significant effect on depression and sleep disorder. Verbal memory improved with administration of 60 mg/day of raloxifene while a mild cognitive impairment risk reduction by 33% was observed with administration of 120 mg/day of raloxifene. Raloxifene was associated with a 50% decrease in the need for prolapse surgery. The result of a meta-analysis showed a significant decline in the plasma concentration of lipoprotein in the raloxifene group compared to placebo (standardized mean difference, -0.43; 10 trials). A network meta-analysis showed that raloxifene significantly decreased the risk of breast cancer (relative risk, 0.572; 95% confidence interval, 0.327-0.881; P = 0.01). In terms of adverse effects of raloxifene, the odds ratio (OR) was observed to be 1.54 (P = 0.006), indicating 54% increase in the risk of deep vein thrombosis (DVT) while the OR for pulmonary embolism (PE) was 1.05, suggesting a 91% increase in the risk of PE alone (P = 0.03). Conclusions: Raloxifene had no significant effect on depression and sleep disorder but decreased the concentration of lipoprotein. Raloxifene administration was associated with an increased risk of DVT and PE and a decreased risk of breast cancer and pelvic organ prolapse in postmenopausal women.

• 대한한방부인과학회지
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• 제31권1호
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• pp.138-146
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• 2018

Objectives: The purpose of this study is to evaluate the effects of Gamiguibi-hwan on Climacteric Syndrome. Method: We treated 50 cases menopausal disorder patients with Gamiguibi-hwan for 12 weeks. We estimated the effects by Menopause Rating Scale (MRS), Pittsburgh Sleep Quality Index (PSQI) and Beck's Depression Inventory II (BDI-II). Results: After treatment, the mean of MRS, PSQI and BDI-II score were decreased. Conclusions: This case shows that Gamiguibi-hwan is effective in treating menopausal disorder patients.