• 대한통합의학회지
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• 제8권2호
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• pp.169-185
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• 2020

Purpose : This study aimed to conduct a comprehensive meta-analysis to evaluate the effect size for pulmonary function and gait capacity of treadmill exercise in stroke patients. In addition, we aimed to examine the current status of treadmill interventions and compare the effect sizes of treadmill training to provide evidence-based practice for future development and application. Methods : The meta-analysis study was conducted using research articles that applied treadmill exercise to stroke patients and were published between January 2005 and February 2020. For a systematic meta-analysis, we conducted a search using the PICOS framework and selected 25 domestic stroke- and treadmill-related studies. The Comprehensive Meta-Analysis program was used to calculate the effect sizes for lung function and gait capacity (6-minute walk test and 10 m walk test). As Cohen's d has a tendency to overestimate the effect size, we used Hedge's g to increase the accuracy in computing the effect size. Results : Based on the results of the meta-analysis, the total effect size of treadmill exercise was 0.535, which was statistically significant, with a medium effect size (p<0.05). The effects of treadmill exercise in stroke patients were divided into dependent variables, namely pulmonary function (0.372) and gait capacity (0.584). In addition, for gait capacity, the effect sizes were evaluated for both the 6-minute walk test (0.756) and the 10 m walk test (0.514). Conclusion : This study provides objective evidence of the effectiveness of treadmill-based gait training programs. We hope that the results of this study will help support the development and implementation of treadmill-based gait training in stroke patients. Treadmill training is expected to improve not only pulmonary function, but also the gait capacity of stroke patients. Long-term investigations on the effects of treadmill training in stroke patients are necessary.

• Journal of Periodontal and Implant Science
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• 제33권1호
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• pp.49-60
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• 2003

Several growth factors and polypeptides are not commonly yet used for regenerators of bone tissue or alveolar bone because of the insufficiency of studies on their side effects, genetic engineering for mass production and stability for clinical application. Recently, many herbal medicines, which have advantage of less side effects and possibility of long-term use, have been studied for their capacity and effects of anti-bacterial, antiinflammatory and regenerative potential of periodontal tissues. Morindae Radix, Cibotium Barometz (L.), Albizziae Cortex, Cistandhis Herba have been traditionally used as medicines for treatment of bone disease in Eastern medicine. The objective of the present study is to examine the ability of alkaline phosphatase (ALP) activity of human fetal osteoblast (hFOB1) when several natural medicines were supplemented. hFOB1 were cultured with Dulbecuo's Modified Eagle's Medium Nutrient Mixture F-12 HAM ( DMEM/F-12 1:1 Mixture, Sigma, USA) and negative control, dexamethasone (positive control), and each natural medicines for 3 days. And then ALP activity was measured by spectrophotometer for enzyme activity and Alizarin red S staining for morphometry. Among the natural medicines of this study, Morindae Radix, Cibotium Barometz (L.) and Cistanchis Herba induced higher activity of ALP synthesis than negative controls in all experimental group. Albizziae Cortex showed mild increases than negative control group. According to measurement of positively stained area, all of the natural medicines of this study increased compared to negative control. Especially, Cibotium Barometz (L.) and Cistanchis Herba showed statistical significance compared to negative control (p<0.05). These results indicate that Morindae Radix, Cibotium Barometz (L.), Albizziae Cortex, Cistandhis Herba have an inducing ability of ALP synthesis on osteoblast.

• 한국건설관리학회:학술대회논문집
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• 한국건설관리학회 2004년도 제5회 정기학술발표대회 논문집
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• pp.246-249
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• 2004

최근 국내 건설경기의 회복세가 뚜렷해지고 건설취업자수도 증가세를 보이고 있으나 인력수급의 양적, 질적 불균형 양상이 나타나고 있고, 경제위기를 겪으면서 건설 생산 방식과 인력 활용 방식이 과도기적 양상을 나타낸다. 또한 기능인력에 대한 수요 증가와 구조적인 공급 부족 현상은 임금 상승을 가속화시켜왔으며, 생산성과 공기 조절을 비롯한 건설 생산활동 전반에 지대한 파급효과를 미치며 건설 인력 수급의 불균형 상태는 부문별로 상이한 취업구조의 변화를 야기한다. 본 연구에서는 기존에 조사된 각 연도의 건설업 임금실태 조사를 비교분석하여 건설인력수급현황을 분석하고 건설 수급 여건에 따른 건설 인력의 취업구조를 파악하여 취업구조 변화의 특성을 살펴보고 시사점을 도출한다.

• Journal of Periodontal and Implant Science
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• 제24권1호
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• pp.98-108
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• 1994

Gingival hyperplasia is frequently associated with the long-term use of phenytoin for control of convulsive disorder. The purpose of this study was to investigate on the effects of lipopolysaccharides (LPS), ursolic acid and oleanolic acid to phenytoin-induced cell activity in human gingival fibroblast. Human gingival fibroblasts were cultured form the healthy gingiva of orthodontic patients. Gingival fibroblasts were trypsinized and transferred to the weels of microtest plates. Fibroblast were cultured in growth medium added $5{\mu}g/ml$ of phenytoin, $5{\mu}g/ml$ of LPS, $10^{-7}M$ of ursolic acid and oleanolic acid. The passage number of cultured fibroblasts were fifth and eight. Cell morphology was examined by inverted microscope and the cell activity was measured by proliferation assay. Ursolic acid significantly modulated cell morphology into globular shape at the concentrantion of $10^{-7}M$ in the presence of phenytoin and LPS, and the cell activity was significantl decreased by ursolic acid or oleanolic acid regardless of the presence of phenytoin and LPS. These results suggested that the increased phenytoin-induced cell activity might be modulated by ursolic acid regardless of the presence of phenytoin and LPS. These results suggested that the increased phenytoin-induced cell activity might be modulated by ursolic acid or oleanolic acid. Further study is needed to clarify their toxicological effects on cellular modulation and mRNA expression change.

• Journal of Chest Surgery
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• 제3권2호
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• pp.91-106
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• 1970

Two groups of left pulmonary-subclavian artery anastomosis were done in 26 adult mongorel dogs. For the first group. the distal end of the subclnvian artery was nnastomosed to the side of the left pulmonary artery, and for the second group, the subclavian end wns anastomosed to the proximal end of the left lower lobe pulmonary artery. Among them, 6 died of bleeding or anesthetic failure during the day of operation, 10 survived 1 to 106 days and the other 10 were sacrificed at various interval. To investigate the relationship between hemodynamic stress and temporal evolution of the pulmonary vascular lesions. the pulmona try and femoral artery pressures, arteriogram and pathohistological specimens were obtained. The following results were obtained. 1. The postoperative pulmonary artery pressures were within normal limits except 2 dogs in the first group, but in nil 12 dogs of the second group, they were in moderate to maked pulmonary hypertension level. 2 After subclavian pulmonary anastomosis, both groups dogs showed increased femond artery pulse pressure. 3. The pulmonary vascular changes were more severe and appeared earlier in the second group dogs compared with the first group.4. The earliest vascular changes appeared in the media of the small muscular arteries and arterioles. 5. Various vascular chaDges were produced in 2 or 3 months. Thereafter, the changes were stationary. 6. Among the first group, two long-term servivors (No. 705 & 713) which had normal pulmonary artery pressure under the anesthesia, also showed various vascular changes as other pulmonary hypertensive dogs. 7. In the early stage medial hypertrophy. interruptio~l of elastic lamellae were found in the small muscular arteries and arterioles, which were followed by intimal proliferation and thrombosis. These findings may suggest some evidences of trauma to the vessels. 8. Pulmonary arteriograms showed irregularity of the intima of the large and medium sized arteries, abrupt ending of some of the small arteries and narrowing of the anastomosis.

• 산업클러스터
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• 제1권1호
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• pp.29-46
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• 2007

이 논문은 우리나라 산업 클러스터 형성여건을 파악하고 정책적 함의를 도출하는데 목적이 있다. 이를 위하여 지역혁신사업 추진 주체들을 대상으로 지역의 클러스터 형성수준을 조사한 설문조사 결과를 활용하였다. 그 결과 수도권과 비수도권, 대도시와 중소도시 간에는 클러스터 형성여건과 발전단계가 상이하다. 집적 등 기반조성기 요인들은 양호하나 형성기 요인들인 전략산업별 연구자, 벤처기업과 대기업 관계, 경영, 금융 및 마케팅 등 기업지원기관 및 분리신설기업 등은 취약한 것으로 나타났다. 따라서 발전된 지역과 저 발전된 지역을 구분하고 지역의 여건과 발전단계에 맞는 다양한 사업을 개발하여 추진할 필요가 있다. 수도권과 지방간의 균형발전이 중요한 현 시점에서 지역혁신사업의 입지는 형평성 보다는 효율성, 분산 보다는 집적, 백화점식 보다는 지역의 특화를 고려하여 선정 추진하는 것이 필요하다. 발전된 지역은 지역내 균형발전 방향, 저 발전된 지역은 지역내 선택과 집중 방향으로 추진할 필요가 있다.

• 한국항만경제학회:학술대회논문집
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• 한국항만경제학회 2007년도 정책세미나 및 국제학술대회
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• pp.255-270
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• 2007

In North-East Asia, Port traffic in Asia-North America sea route has been rapidly increasing due to economic growth in China and ASEAN. Furthermore, the major shipping companies directly call at northern chinese ports like Qingdao, Dalian and Tianjin without passing through Korean ports on Asia-North America sea route. To acquire a port traffic and develop a hub port, governments in North-East Asia have intensively invested in the development of port. Therefore, Busan new port and Gwangyang port have been developed in Korea. According to the medium-long term development planning, the port should give a enormous budget investment for the port facilities construction. So the inaccurate estimation may lead to the unreasonable port development policy. Firstly, based on the estimation of Chiang Bong-Gyu & Yang Hang Jin(2005), this study gave a comparison with the estimation of Ministry of Maritime Affairs and Fisheries(2001) and OSC/Glori(2005). Secondly, taking into account the influence factors for port traffic, this study made an estimation of port traffic for Busan new port. On the basis of this estimation, this study is compared with the estimation of Ministry of Maritime Affairs and Fisheries(2001) and OSC/Glori(2005). In conclusion, in case of the development of Busan new port, based on the estimation of Ministry of Maritime Affairs and Fisheries(2001), this study should the high possibility that the Busan new port will be serious lack of the port facilities in the year of 2011. And according to the OSC/Glori(2005)'s estimation result, there is a lack of the port facilities, though we have modified the port investment plan.

• 융합보안논문지
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• 제20권1호
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• pp.15-24
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• 2020

사이버터러나 사이버전(cyber warfare)은 더 이상 가상적 상황이 아닌 현실적이며, 실체적인 안보상황으로 상대국의 군사지휘체계는 물론 통신, 에너지, 금융, 수송체계 등 국가 주요기능 무력화의 전쟁 개념의 확대로 재인식과 국가적 차원에서의 사이버보안 미래전략 수립이 필요하다. 각 국의 사이버전(戰) 동향 분석 및 국내 사이버전(戰) 현황 분석을 통해 사이버보안 기술개발과 산업육성, 그리고 인력양성 전략 마련과 기존의 정보보호 정책과 법·제도을 바탕으로 신규 정책수요에 대한 체계적 발굴과 이를 통해 지속적 발생 가능한 국가적 위기를 효율적으로 관리하고, 효과적이며 능동적으로 사이버전(戰)에 대응할 수 있는 중·장기적 사이버보안 미래전략 수립에 대하여 제안한다.

• 한국보육지원학회지
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• 제13권5호
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• pp.21-41
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• 2017

Objective: This study purposed to provide implications in regards to the Moon Jae-in Administration that launched in May 2017. Three sectors of childcare polices on administration of childcare centers were reviewed in terms of supporting the healthy development of young children. Methods: Medium and long-term childcare plans and the main policies of previous administrations since 2004 when the Childcare Act was completely reformed, as well as the 'Five-year policy for the Moon Jae-in administration of state affairs' that was announced on July, 2017, were reviewed in terms of publicness of childcare, regulations on operation of childcare services, and customized childcare programs for diverse needs. Results: It was proposed that the concept of publicness of childcare should be conservative when focusing on public childcare centers. The regulations on operating childcare services should focus on improving structural dimensions of childcare quality to keep the well-being of children a top priority. Furthermore, diverse programs should be designed and implemented to satisfy changes in childcare surroundings and the various needs of children and their families. Conclusion/Implications: The Moon Jae-in administration is expected to outline childcare policies and carry out tasks under the new paradigm. The healthy development of young children should be embodied as the final goal that forms the vision of childcare policies based on publicness, rationality, and diversity.

• 한국건설관리학회논문집
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• 제10권4호
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• pp.14-25
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• 2009

공동주택 개발사업은 대규모의 자원과 인력이 투입되는 중장기 복합공정 사업으로 사업 내 외적 영향요인이 복합적으로 관계되는 바, 사업추진 시 현장여건을 비롯한 정치 경제 사회 분야의 내 외부 불확실성 요소로 인한 많은 사업 리스크가 발생하게 된다. 이러한 리스크는 사업의 성패를 결정짓는 중요한 인자로서 작용하게 되며, 종국에 기업의 수익 및 재무구조를 변화시키는 중점 관리요인으로 그 중요성이 크게 대두되고 있어 이에 따른 리스크 저감을 위한 방안 및 효율적인 대책이 필요하다. 이와 같은 관점에서 본 연구에서는 건설프로젝트 중 공동주택 개발사업을 대상으로, VE기반 리스크 관리모델 및 절차를 수립하고 이에 따른 사업 추진 시 기획 및 설계, 시공, 유지관리에 이르는 전 단계에서의 발생 가능한 리스크 요인을 총 3단계 10분류 81개 항목으로 도출, 분석하고, 각각의 리스크 항목별 중요도를 가치공학(VE)을 기반으로 하여 평가 제시함으로써 궁극적으로 개발사업의 성공적인 추진과 이에 따른 공공 및 민간 건설 산업의 경쟁력을 확보할 수 있는 기초자료를 제시하였다.