• Journal of Korean Medical classics
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• v.24 no.4
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• pp.55-67
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• 2011

Through analyzing the frequencies of medicinal herb combinations in the prescriptions of "Bangyakhappyeon(方藥合編)", we could understand the characteristics of prescription composition and author's medical thoughts. So we conducted this study that analyze combination of 324 medicinal herbs in 467 prescriptions, and found meaningful combinations of 5,045. Among these, the most meaningful combination is the one of 10 herbs, Glycyrrhiza uralensis Fischer, Angelica gigas Nakai, Ziziphus jujube Mille, Atractylodes japonica Koidzumi, Poria cocas Wolf, Zingiber officinale, Rehmanniae radix preparata, Cinnamomum loureirii, Panax ginseng C.A.Meyer, Astragalus membranaceus. This combination is Sibjeondaebo-tang(Shiquandabu-tang) without Cnidium officinale and Paeonia japonica which compose Samul-tang(Siwu-tang). It means this combination is kind of modified Sibjeondaebo-tang(Shiquandabu-tang), which is more effective in tonifying qi than tonifying blood. Prescriptions of "Bangyakhappyeon(方藥合編)" involve herbs mostly used to improve weak and frail health and the herbs which are more effective in tonifying qi than tonifying blood. Through this study, we know the author' s one of medical view points on tonifying qi and blood, attaching importance to tonifying qi relatively to tonifying blood.

• Journal of Korean Medicine for Obesity Research
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• v.10 no.2
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• pp.41-49
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• 2010

Objectives This study is to suggest the herbal bathing and the manual therapy with herbs for obesity patients according to the Sasang constitutional medicine. Methods In this study, first, we found the books, web sites and papers about bathing. And also we classified the herbs those are used each therapy according to the Sasang constitutional medicine theory. Results and Conclusions: We make good used of salts, sulfur or herbal agents inserted into a bath, when we are bathing. And we knew that "The Pinda manual therapy" is a therapy with medical herbs in the West. The Pinda manual therapy is a fomentation therapy with wrapped in cloth and steamed medical herbs. According to Sasang constitutional right to bath in each prescription were as follows. Taeeumin: Taeeumin Galgeunhaegi-tang. / Soyangin: Soyangin Hyeongbangpaedok-san. / Soeumin: Gunggwihyangso-san, Soeumin Kwakhyangjeonggi-san. / Taeyangin: Ogapijangchuk-tang. And also, by Sasang constitution, applicable herbs to the Pinda therapy were as follows. Taeeumin: Seokchangpo, Wonji, Gobon, Gamguk, Sokdan, Wiryeongseon.. / Soyangin: Hyeonggae, Bangpung, Bakha, Ganghwal, Dokhwal. / Soeumin: Kwakhyang, Soyeop, Danggwi, Cheongung, Sesin, Jinpi. / Taeyangin: Ogapi, Mokgwa, Nogeun, Gyomaek. It will be need to more study for effective clinical applications.

• THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
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• v.4 no.1
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• pp.211-232
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• 1998

Because there were lots of side effects and tolerances to the existing anticancer therapeutics, the experiment extracting the anticancer effect from medicinal herbs is in progress liviely. Therefore the purpose of this study were to research the tendency and the course of anticancer studies. To research the tendency of anticancer studies, medicinal herbs of fifty three experimental papers were analyzed and to examine the course of studies, anticancer papers in the medical world were used. The obtained results were as follows: Methods of herbal medicinal treatments were elimination the pathogenic factor(祛邪) and supporting healthy energy(扶正) method used. In this study, immediately tumor bearing and immune response were the most important point. The subject of immediately tumor bearing was not in the specific cancer but in the influence on the life span of general cencerous cells. In the experimental study of immune response, the effect on NK cell activity of medicinal herbs most studied. The combined usage of medicinal herbs and anticancer agent mostly intended to know whether it inhibits the tumor cell growth. The serum test and blood cell number test show if medicinal herbs inhibit side effect of anticancer agent. More than 80 percents of used medicinal herbs, there were anticancer activities. However anticancer experimental studies using medicinal herbs two weak points. The one, it was difficult to choose a prescription according to differentiation of symptoms and signs(辨證論) of the Oriental Medicine, because we put to the test not a man but a mouse. The other, as we observed the indirect effect of the whole physiological regulation caused by synergic effects of the complex prescription, we don't understand the detailed mechanism of the herb. Therefore, if the anticancer effect of the herb is proved the experiment, we should research the concrete medical action of medicinal herbs and immunological analysis of herbal medicines to the body.

• 대한한약학회:학술대회논문집
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• 2007.11a
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• pp.129-144
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• 2007

In order for stable demand-supply and regularity of distribution, "The regulations for management of demand-supply and distribution of medicinal herbs" were established on 1995. Therefore, the medicinal herbs of good quality have been controled to be distributed in the market. However, to be wide of the purpose, the standardized sound distribution system was caused due to the governmental control on demand-supply to protect domestic farmers who produce the material for medicinal herbs, which results in the over distribution of non-standardized or illegally imported medicinal herbs. In addition, because of the distribution of faulty or poor medicinal herbs, there are chances of affecting bad effects on public health. The standardized medicinal herbs cover 514 different kinds in total, of which 69 products are specified to be standardized in the oriental medicine product companies. Also, in order to protect farmers who produce the materials for medicinal herbs, the amount of imported materials are regulated in normal times. The 14 different materials for medicinal herbs, which are allowed to be imported to a certain amount only when the shortage of goods or sudden rise of prices is to happen, are frequently introduced into domestic market as food not as medical usage, and the origin of those illegally changes to home cropped one for the distribution in the market. In addition, the system of distribution are to be disordered and the condition for the distribution of medicinal herbs of good quality can not be made since they illegally changes the usage of the materials for medicinal herbs from their original one and can not be regulated by the domestic laws.

• 대한상한금궤의학회지
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• v.4 no.1
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• pp.13-28
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• 2012

Objective : The purpose of this study is to suggest medical approach to musculoskeletal system disorders using the decoction of Sanghan-Geumgwe. We studied cases of Ling-Gui-Gan-Zao-Tang prescribed patients to evaluate the clinical efficacy in musculoskeletal system disorders Method : We devised medical approach of Sanghan-Geumgwe in musculoskeletal disorders as follows. First, we chose ryeon-je(攣劑) and soo-je(水劑) herb medicine, commonly used in musculoskeletal disorders. In the selected herb group, we designated ryeon-je(攣劑) to be first key herbs, Soo-Je(水劑) as the second key herb, and other herb groups as third key herb. In this sequential selection and exclusion process, herbs were chosen based upon yak-neung-hyo-seon (藥能效選). Combination of those selected herbs drew pre-prescription group, finally prescription were made by the prescription criteria. Results : Based on the medical approach of decoctions of Sanghan-Geumgwe, we chose Ling-Gui-Gan-Zao-Tang to treat many kinds of musculoskeletal system disorders. And we achieved higher results on treatment for musculoskeletal system disorders. Conclusions : The medical approch using the decoctions of Sanghan-Geumgwe is very useful in choosing accurate prescriptions for patients with musculoskeletal system disorders in clinic.

• The Journal of Internal Korean Medicine
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• v.22 no.1
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• pp.73-78
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• 2001

After examining and analysing the medicinal herbs of fifty-three experimental papers, we studied their effects on immediate tumors in specific cancers. We did not study the influence on the life span of general cancerous cells. We looked to see if the combined usage of medicinal herbs and anticancer agents inhibited the tumor cell's growth. The serum test and blood cell count test showed if the medicinal herbs inhibited the side effects of the anticancer agent. The test showed that more than 80 percent of used medicinal herbs, brought anticancer activities. However, anticancer experimental studies using medicinal herbs have draw-backs. First, it is difficult to choose a prescription using the standards of Oriental Medicine because we are testing a mouse not a man. Second, because we only observed the indirect effect on the whole physiological regulation caused by the synergic effects of the complex prescription, we are not able to understand the detailed mechanism of the herbs. Therefore; if the anticancer effect of the herbs is proved by the experiment, we need to research the concrete medical action of medicinal herbs and the immunological analysis of herbal medicines on the body.

• Microbiology and Biotechnology Letters
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• v.21 no.2
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• pp.187-191
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• 1993

In order to find out an anticariogenic substance, antibacterial activities of some medical herbs and spices against Streptococcus mutans were investigated. The essential oils of oregano, thyme, sage, fennel, nutmeg, rosemary, calamus and cassia cortex were shown antibacterial effect against S. mutans. The essential oil of oregano among other tested medical herbs and spices showed the most active antimicrobial activity. The essential oil of oregano inhibited the activity of glucosyltransferase from S. mutans. The minimal inhibition concentration of oregano essential oil was determined as 0.05nl/ml. The activity of glucosyltransferase from S. mutans was inhibited in the presence of oregano essential oil.

• Journal of Korean Medical classics
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• v.30 no.4
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• pp.69-82
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• 2017

Objective : This study was conducted to infer the effect of superficies-resolveing herbs by analyzing effect terms which have extracted and refined, based on four temperatures and five tastes. Method : Firstly, temperatures, tastes and effect terms were extracted from the 27 kinds of superficies-resolving herbs written in Herbology. Then, each effect terms was divided into single meaning term and refined as typical term, using the inclusive effect terms I established. After that, herbs were grouped by tastes and found the effect terms which are mentioned most frequently. And it could be supposed to be classified into each herb's new effects based on the relationship between properties and those effect terms. It is also inferred into new tastes from some herbs by analysing the representative effects group of each taste and finding which other tastes can be related to each herb's effect. Result & Conclusion : All the superficies-resolving herbs can have wind-dispelling effect and superficies-resolving effect, except Bulpleuri Radix. This herb is able to has just the wind-dispelling effect. And it's more appropriate to categorize Bulpleuri Radix to heat-clearing herb group than superficies-resolving herb group, considering its several, distinctly cold characteristics. Some effects are concentrated to wind-cold-dispersing herb group and others to wind-heat-dispersing herb group. Each tastes has its own representative effect group. And, according to its tastes' representative effect, some of herbs are reasonable to get new effect term. With not so feasible reason, 4 kinds of herbs are supposed to contain all of hot, bitter, and sweet tastes. Also It's needed to study much deeper whether Perillae Herba, Zingiberis Rhizoma Crudus and Elsholtziae Herba are belong to superficies-resolving herb group or to interior-warming or damp-dissolving aromatic herb group.

• Journal of Korean Medical classics
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• v.21 no.1
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• pp.143-151
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• 2008

Objective : Classification of herbal formulas through the analysis of compositional herb's is a suitable method in the aspects of the effective applications of herbal formulas. However, these classification methods have some problems in dealing with lots of herbal formulas because the estimations of herbal formula's effects are dependent upon one's memory. In this study, we aimed to establish the effective methodology to elicit the classified herbal formula's chart by introducing the DB systems without interfering with non-standard terms. Results : We have known that this plan is realized by follow methods. We entered the herbs informations of the composition of herbal formulas into database, made an alias tables of corresponding herbs, and achieved standardization of herb's informations. Using these databases, we made the classified herbal formula's chart according to the presence and the treatment informations of herbs.

• Journal of Acupuncture Research
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• v.21 no.3
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• pp.265-282
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• 2004

Objective : The aim of this study was to review systemically clinical trials on the effectiveness and safety of herbal medicines in the treatment of osteoarthritis. Methods : Computerized literature searches were carried out on seven electronic databases, and hand-searching on some chinese medical journals in library of Kyung Hee Medical Center. Trial data were extracted in a standardized, predefined manner and assessed independently. Results : 1. Thirty reports of clinical trials and two reports of meta-analyses concerning herbal medicine were collected and reviewed. Among these reports three medical herbs were applied as topical medicine and others as internal medicine. 2. The western studies established NSAIDs or placebo as their control group. Five chinese reports established formulated herb pill(Ruanshnagshenjin pill) as their control group and Six did not establish a control group at all. 3. ACR was the most highly used diagnostic criteria in the western studies while the Chinese used their official criteria established by their government or the criteria of their text books. 4. 20 reports chose the Lequesne functional index, SHAQ, WOMAC OA index, AIMS, and their own unique scoring system as the criteria of analysing the effect. Others chose clinical symptoms, articular functions, and lab finding as their criteria. 5. 7 single herbs and 19 formulated herbs were studied. Among the formulated herbs, Achyranthes japonica was studied in 10 of the studies and Angelica gigantis Radix in 8, making them the most often studied herbs among the studies.