Systemic review: Herbal Medicines in the Treatment of Osteoarthritis in Pubmed and Chinese Medical Journals

퇴행성관절염(退行性關節炎) 한방치료(韓方治療)에 대(對)한 최근(最新) 연구(硏究) 동향(動向) - 임상연구(臨床硏究) 방법론(方法論)을 중심(中心)으로 -

  • Seo, Byung-kwan (Department of Acupuncture & Moxibustion, Oriental Medical Hospital, Kyung-Hee University) ;
  • Ryu, Seong-ryong (Department of Acupuncture & Moxibustion, Oriental Medical Hospital, Kyung-Hee University) ;
  • Lee, Song-shil (Oriental Medicine Research Center for Bone & Joint Disease) ;
  • Huh, Jeong-eun (Oriental Medicine Research Center for Bone & Joint Disease) ;
  • Baek, Yong-hyeon (Department of Acupuncture & Moxibustion, Oriental Medical Hospital, Kyung-Hee University) ;
  • Lee, Jae-dong (Department of Acupuncture & Moxibustion, Oriental Medical Hospital, Kyung-Hee University) ;
  • Choi, Do-young (Department of Acupuncture & Moxibustion, Oriental Medical Hospital, Kyung-Hee University) ;
  • Cho, Yoon-je (Department of Orthopaedic Surgery, College of Medicine, Kyung-Hee University, East-West Arthritis Center, Kyung-Hee Medical Center, Kyung-Hee University) ;
  • Kim, Nam-jae (East-West Medical Research institute, Kyung-Hee University) ;
  • Park, Dong-suk (Department of Acupuncture & Moxibustion, Oriental Medical Hospital, Kyung-Hee University)
  • 서병관 (경희대학교 부속한방병원 침구학교실) ;
  • 류성룡 (경희대학교 부속한방병원 침구학교실) ;
  • 이송실 (골관절질환 한방연구센터) ;
  • 허정은 (골관절질환 한방연구센터) ;
  • 백용현 (경희대학교 부속한방병원 침구학교실) ;
  • 이재동 (경희대학교 부속한방병원 침구학교실) ;
  • 최도영 (경희대학교 부속한방병원 침구학교실) ;
  • 조윤제 (경희대학교 의과대학 정형외과학교실, 경희의료원 동서관절센터) ;
  • 김남재 (경희대학교 동서의학연구소) ;
  • 박동석 (경희대학교 부속한방병원 침구학교실)
  • Received : 2004.05.14
  • Accepted : 2004.05.15
  • Published : 2004.06.20

Abstract

Objective : The aim of this study was to review systemically clinical trials on the effectiveness and safety of herbal medicines in the treatment of osteoarthritis. Methods : Computerized literature searches were carried out on seven electronic databases, and hand-searching on some chinese medical journals in library of Kyung Hee Medical Center. Trial data were extracted in a standardized, predefined manner and assessed independently. Results : 1. Thirty reports of clinical trials and two reports of meta-analyses concerning herbal medicine were collected and reviewed. Among these reports three medical herbs were applied as topical medicine and others as internal medicine. 2. The western studies established NSAIDs or placebo as their control group. Five chinese reports established formulated herb pill(Ruanshnagshenjin pill) as their control group and Six did not establish a control group at all. 3. ACR was the most highly used diagnostic criteria in the western studies while the Chinese used their official criteria established by their government or the criteria of their text books. 4. 20 reports chose the Lequesne functional index, SHAQ, WOMAC OA index, AIMS, and their own unique scoring system as the criteria of analysing the effect. Others chose clinical symptoms, articular functions, and lab finding as their criteria. 5. 7 single herbs and 19 formulated herbs were studied. Among the formulated herbs, Achyranthes japonica was studied in 10 of the studies and Angelica gigantis Radix in 8, making them the most often studied herbs among the studies.

Keywords

Acknowledgement

Supported by : 보건복지부