• Journal of Information Processing Systems
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• 제17권3호
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• pp.615-629
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• 2021

With the development of mobile edge computing, how to utilize the computing power of edge computing to effectively and efficiently offload data and to compute offloading is of great research value. This paper studies the computation offloading problem of multi-user and multi-server in mobile edge computing. Firstly, in order to minimize system energy consumption, the problem is modeled by considering the joint optimization of the offloading strategy and the wireless and computing resource allocation in a multi-user and multi-server scenario. Additionally, this paper explores the computation offloading scheme to optimize the overall cost. As the centralized optimization method is an NP problem, the game method is used to achieve effective computation offloading in a distributed manner. The decision problem of distributed computation offloading between the mobile equipment is modeled as a multi-user computation offloading game. There is a Nash equilibrium in this game, and it can be achieved by a limited number of iterations. Then, we propose a distributed computation offloading algorithm, which first calculates offloading weights, and then distributedly iterates by the time slot to update the computation offloading decision. Finally, the algorithm is verified by simulation experiments. Simulation results show that our proposed algorithm can achieve the balance by a limited number of iterations. At the same time, the algorithm outperforms several other advanced computation offloading algorithms in terms of the number of users and overall overheads for beneficial decision-making.

• Asian Pacific Journal of Cancer Prevention
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• 제13권8호
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• pp.4187-4190
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• 2012

Aims and Background: To evaluate the efficacy of a combination of aprepitant and conventional antiemetic therapy in patients with advanced or recurrent lung cancer receiving moderately emetogenic chemotherapy (MEC). Methods: Patients with advanced or recurrent lung cancer who were treated with MEC regimens at the Department of Respiratory Medicine, Fukuoka University Hospital, were included and classified into the following groups: control group (treatment: 5-HT3 receptor antagonists + dexamethasone) and aprepitant group (treatment: 5-HT3 receptor antagonists + dexamethasone + aprepitant). The presence or absence of chemotherapy-induced nausea and vomiting (CINV) was evaluated according to the Common Terminology Criteria for Adverse Events (CTCAE) v4.0; patients with grade 1 or above were considered positive for CINV. Food intake per day, completion of planned chemotherapy, and progression-free survival (PFS) achieved by chemotherapy were investigated. Results: The complete suppression rate of nausea in the aprepitant group was significantly higher than that in the control group (p = 0.0043). Throughout the study, the food intake in the aprepitant group was greater than that in the control group, with the rate being significantly higher, in particular, on day 5 (p = 0.003). The completion rate of planned chemotherapy was also higher in the aprepitant group (p = 0.042). PFS did not differ significantly, but tended to be improved in the aprepitant group. Conclusions: The aprepitant group showed significantly higher complete suppression of nausea, food intake on day 5, and completion of planned chemotherapy than the control group.

• 인터넷정보학회논문지
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• 제20권5호
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• pp.113-119
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• 2019

최근 상용화된 5G 이동통신의 주요한 특징은 High Data Rate와 Connection Density 그리고 Low Latency로 대표할 수 있는데, 이중 기존 4G와 가장 차별되는 특징은 Low Latency로 다양한 새로운 서비스 제공의 기반이 될 것이다. 이러한 특징을 활용한 서비스로는 AR, 자율주행 등이 검토되고 있으며 관련표준에서도 5G Network Latency 논의를 진행하고 있다. 그러나 서비스 관점의 E2E Latency 논의는 많이 부족한 것이 사실이다. 5G에서 Low Latency를 달성을 위한 최종목표는 RTD 기준 Air Interface 1ms 달성으로 이는 '20년 초 Rel-16을 통한 URLLC(Ultra-reliable Low Latency Communications)를 통해 가능하며, 추가적으로 MEC(Moble Edge Computing)를 통한 Network latency 감소도 연구 중이다. 전체 5G E2E Latency는 5G Network 관련 외에도 다양한 요인이 존재하는데, 주요 요인으로는 5G Network과 서비스 제공을 위한 IDC Server 사이의 경로에 놓인 선로/장비 Latency, 단말 App과 Server 내 서비스 처리를 위한 Processing Latency 등이 존재한다. 한편, 서비스 초기 Setup을 위한 Latency와 서비스가 지속 중인 경우의 Latency를 구분하여 세부 서비스 요구사항에 대하여 연구하는것도 필요한데, 이를 위해 본 논문에서는 서비스 초기 Setup과 관련하여 다음과 같은 세가지 요인에 대하여 검토를 진행하였다. 첫째로 (1) Data호 Setup시에 발생 가능한 Latency, 둘째 전력 효율화를 위한 (2) CRDX On/Off에 따른 영향, 마지막으로 (3) H/O가 발생되는 경우에 Latency에 대하여 Latency에 미치는 영향을 실험과 분석을 제시했다. 이를 통해 우리는 Low Latency가 필요한 서비스의 초기 Setup시에 Latency와 관련된 서비스 요구사항 및 기획에 기여할 수 있을 것으로 기대한다.

• Corrosion Science and Technology
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• 제22권5호
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• pp.341-350
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• 2023

In the present study, effects of a thin Zn-flash coating on hydrogen evolution, infusion, and embrittlement of advanced high strength steel during electro-galvanizing were examined. The electrochemical permeation technique in conjunction with impedance spectroscopy was employed under applied cathodic polarization. Moreover, a slow-strain rate test was conducted to evaluate loss of elongation (i.e., indicative of hydrogen embrittlement (HE)) and examine fracture surfaces. Results showed that the presence of a thin Zn-flash coating, even when it was not distributed uniformly, reduced hydrogen evolution rate and substantially impeded infusion of hydrogen into the steel substrate. This was primarily due to a hydrogen overvoltage on Zn coating and trapping of hydrogen at the interface of Zn coating/flash coating/steel substrate. Consequently, the sample with flash coating had a smaller HE index than the sample without flash coating. These results suggest that a thin Zn-flash coating could be an effective technical strategy for mitigating HE in advanced high-strength steels.

• 대한수의학회지
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• 제48권1호
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• pp.75-81
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• 2008

The rapid evolution of antibiotic resistance in Staphylococcus (S.) aureus is of considerable concern. Methicillin-resistant S. aureus (MRSA) strains are especially one of the greatest public concerns since the treatment of infections is more difficult when encountering resistance. In this study, we conducted a nationwide survey on the antimicrobial resistance of S. aureus isolated from raw meat samples collected from 16 countries, including Korea, and investigated the prevalence of MRSA as a possible source of human infection. Of 1,984 meat samples, S. aureus was isolated from 218 (11.0%) samples consisting of 23 (12.1%) from domestic meat and 195 (10.9%) from imported meat. The isolation rates of poultry meat, pork and beef were 12.8%, 7.0% and 10.0%, respectively. With regard to imported meat, the incidence varied from 4.8% to 16.6% from 13 countries, with the exception of Austria and Poland. In a resistance test to 20 antimicrobial agents, one hundred and eighty-four isolates (84.4%) were resistant to one or more antimicrobial agents tested. Especially, 17 (7.8%), 124 (56.9%) and 28 (12.8%) isolates showed a resistance to 3, 2 and 1 drugs, respectively. One isolate originating from domestic beef was resistant to 7 drugs. Another isolate originating from imported poultry meat showed resistance to oxacillin and methicillin by the disk diffusion test and minimal inhibition concentration methods, but showed negative for detection of the mecA gene.

• 대한물리치료과학회지
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• 제3권1호
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• pp.843-853
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• 1996

The purpose of this study was to determine whether extension exercise is effective in reducing low back pain. Nine patients with low back pain were randomly assigened to one of two groups-one was an experimental group in which the patient were treated with extension exercise(McKenzie method) and conservative therapy. The other was a control group in which the patients were treated with conservative therapy only. Treatment was performed for a period of ten days during Which we examed each patient three times: the first exam was done at the begining of treatment, the second after fives days, and the third after ten days. We used 'The Oswestry low back pain disability questionnaire'(r=.99) as the examination tool. The results were as follows: 1. Both experimental and control groups showed nonsignificant differences before and after treatment, and the between group difference was also non-significant(P>.05). 2. There was no effective reduction of low back pain by MecKenzie's extension exercise(p>.05). We admit that our study protocol had several shortcomings. If they had been accounted for, the result might have been different. Further study should be done with a better experimental design, a larger sample, and a longer experimental duration.

• 인터넷정보학회논문지
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• 제22권6호
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• pp.1-8
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• 2021

With the rapid growth of intelligent devices and communication technologies, 5G network environment has become more heterogeneous and complex in terms of service management and orchestration. 5G architecture requires supportive technologies to handle the existing challenges for improving the Quality of Service (QoS) and the Quality of Experience (QoE) performances. Among many challenges, traffic steering is one of the key elements which requires critically developing an optimal solution for smart guidance, control, and reliable system. Mobile edge computing (MEC), software-defined networking (SDN), network functions virtualization (NFV), and deep learning (DL) play essential roles to complementary develop a flexible computation and extensible flow rules management in this potential aspect. In this proposed system, an accurate flow recommendation, a centralized control, and a reliable distributed connectivity based on the inspection of packet condition are provided. With the system deployment, the packet is classified separately and recommended to request from the optimal destination with matched preferences and conditions. To evaluate the proposed scheme outperformance, a network simulator software was used to conduct and capture the end-to-end QoS performance metrics. SDN flow rules installation was experimented to illustrate the post control function corresponding to DL-based output. The intelligent steering for network communication traffic is cooperatively configured in SDN controller and NFV-orchestrator to lead a variety of beneficial factors for improving massive real-time Internet of Things (IoT) performance.

• 대한간호학회지
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• 제37권6호
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• pp.976-985
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• 2007

Purpose: The aim of this study was to identify the present situation of hospital infection and route of infection by clarifying the transmission aspect of methicillin-resistant Staphylococcus aureus(MRSA) in a Neurosurgical Intensive Care Unit by analysing genotype. Methods: MRSA was cultured from twenty five patients with a tracheostomy, twenty five health care workers, and environments in the Neurosurgical Intensive Care Unit of one hospital in D city. Data was collected from December 21, 2004 to November 5, 2005. MRSA isolates representing each genotype were analyzed by spaA typing and a multiplex PCR method capable of identifying the structural type of the staphylococcal cassette chromosome mec(SCCmec) carried by the bacteria. Results: As the same genotype and gene sequence were found among health care workers, patients, and environments, it was assumed that there was cross transmission among them. Conclusion: This study suggests that first, as the hospital infection by MRSA between health care workers and patients in the Neurosurgical Intensive Care Unit was due to result of cross transmission and the relevance of transmission between them was verified, it is necessary to take preventive measures and conduct education. Secondly, development of nursing interventions and study of infection are needed. Thirdly, consistent investment in prevention against hospital infections and environmental renovation is needed.

• Asian-Australasian Journal of Animal Sciences
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• 제18권6호
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• pp.884-891
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• 2005

This paper describes the purification and properties of a multicatalytic proteinase complex, proteasome, from bovine skeletal muscle, in comparision with proteasome prepared from other species or organs. The purified bovine skeletal muscle proteasome exhibited a single band on polyacrylamide gel electrophoresis under nondenaturing conditions. Bovine skeletal muscle proteasome degraded synthetic peptides maximally at pH 8.0. Relative to pH 8.0, activities were gradually decreased with the lowering pH, but the extent of decrease was substrate-dependent, and the activity at pH 5.5 still retained 78-10% of the activity at pH 8.0, indicating the possibility that the proteasome is active in muscle during aging. When the proteasome was heated at 60$^{\circ}C$ for 15 or 30 min and treated in the presence of 0.0125% SDS, the activity increased over 1.8 and 3.1 times (LLVY (Suc-Leu-Leu-Val-Tyr-NH-Mec) as a substrate), respectively. These results (activation with heat or SDS) indicate that the hydrolytic activity of proteasome was stimulated under mild denaturing conditions. The characteristics of the bovine skeletal muscle proteasome obtained in our experiment were almost the same as those of the proteasome prepared from other species or organs.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제16권8호
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• pp.2490-2506
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• 2022

In Mobile Edge Computing (MEC), attackers can speculate and mine sensitive user information by eavesdropping wireless channel status and offloading usage pattern, leading to user privacy leakage. To solve this problem, this paper proposes a Privacy-preserving and Energy-efficient Offloading Algorithm (PEOA) based on Lyapunov optimization. In this method, a continuous Markov process offloading model with a buffer queue strategy is built first. Then the amount of privacy of offloading usage pattern in wireless channel is defined. Finally, by introducing the Lyapunov optimization, the problem of minimum average energy consumption in continuous state transition process with privacy constraints in the infinite time domain is transformed into the minimum value problem of each timeslot, which reduces the complexity of algorithms and helps obtain the optimal solution while maintaining low energy consumption. The experimental results show that, compared with other methods, PEOA can maintain the amount of privacy accumulation in the system near zero, while sustaining low average energy consumption costs. This makes it difficult for attackers to infer sensitive user information through offloading usage patterns, thus effectively protecting user privacy and safety.