• Sleep Medicine and Psychophysiology
• /
• v.19 no.2
• /
• pp.84-88
• /
• 2012

Introduction: The objective of the present study was to investigate the independent effects of major depressive disorder (MDD) and insomnia on somatization, respectively. Methods: A total of 181 participants (73 males and 108 females ; mean age $41.59{\pm}8.92$) without serious medical problem were recruited from a community and a psychiatric clinic in Republic of Korea. Subjects were divided into 4 groups based on the Structured Clinical Interview for DSM-IV axis I disorder (SCID-IV) and sleep questionnaire : 1) normal controls (n=127), 2) primary insomnia (n=11), 3) MDD without insomnia (n=14), and 4) MDD with insomnia (n=29). All participants were requested to complete the somatization subscores of the Symptom Checklist-90-Revised (SCL-90-R). Results: There were significant between-group differences in somatization score (F=25.30, p<0.001). Subjects with both MDD and insomnia showed higher somatization score compared to normal control (p<0.001), subjects with primary insomnia (p=0.01), or MDD subjects without insomnia (p<0.001). Subjects with primary insomnia had higher somatization score than normal controls (p<0.01), while there was no significant difference between MDD subjects without insomnia and normal controls. In multiple regression, presence of insomnia predicted higher somatization score (beta=0.44, p<0.001), while there was only non-significant association between MDD and somatization (beta=0.14, p=0.08). Conclusion: In the current study, insomnia was associated with somatization independently from major depression. Subjects with primary insomnia showed higher somatization. Within MDD patients, presence of insomnia was related to higher somatization. Our finding suggests that insomnia may partly mediate the relationship between depression and somatization.

• Journal of Korean Society of Environmental Engineers
• /
• v.27 no.7
• /
• pp.777-784
• /
• 2005

The first flush phenomenon is defined as the initial period of road runoff during which the concentration of pollutants was significantly high. Road runoff contains significant loads of micro-particles, heavy metals and organic constituents. There were two major objectives of this study. The first objective was to characterize the road runoff. The second objective was to measure and evaluate particle sire distribution of the road runoff, Stormwater runoff was monitored on two sites of four lane road areas along with traffic volume. A total six storm events were monitored to characterize the road runoff. The quantity of road runoff and quality constituents, including chemical oxygen demand ($COD_{Cr}$), suspended solids(SS), total Kjeldahl nitrogen (TKN), ortho-phosphorus ($PO_4-P$), total phosphorus(TP), heavy metals and particle size distribution were analyzed. The results indicate that the concentration of SS, $COD_{Cr}$, TKN and TP ranges were $45{\sim}2,396\;mg/L$, $40{\sim}931\;mg/L$, $0.1{\sim}19.6\;mg/L$, and $0.2{\sim}25.1\;mg/L$, respectively. The results of the regression analysis between SS and the others constituents shows that $COD_{Cr}$, TP, Cu, Pb were highly correlated. And the results showed that the mean range of particle size and uniformity coefficient for road runoff were $6.7{\sim}23.4{\mu}$ and $6.4{\sim}10.2$, respectively.

• The Journal of Korean Academy of Prosthodontics
• /
• v.58 no.3
• /
• pp.201-206
• /
• 2020

Purpose: The purpose of this study is to evaluate the antimicrobial activity on the dental bur with fluoride for S. mutans. Materials and methods: 0 ppm, 300 ppm, 500 ppm, 1,000 ppm, 1,450 ppm fluoride ion is added to a specimen. S. mutans was incubated for 24 hours, the number of S. mutans were counted. Kruskal-Wallis and MannWhitney analysis were used SPSS 25.0 (IBM SPSS 25.0, Chicago, IL, USA). Results: The mean S. mutans counts of 0 ppm, 300 ppm, 500 ppm, 1,000 ppm, and 1,450 ppm were 374.0 ± 12.6, 251.0 ± 66.7, 111.4 ± 35.6, 41.6 ± 11.7 and 13.2 ± 4.6, respectively. All groups except the control and 300 ppm showed statistically significant. Conclusion: Thus, more than 500 ppm fluoride ion showed the statistically significant antimicrobial activity. 1,450 ppm group showed the highest antimicrobial activity. This study showed the clinical possibility for dental caries protection and antimicrobial activity of dental bur.

• Journal of Bio-Environment Control
• /
• v.33 no.2
• /
• pp.79-87
• /
• 2024

This study confirmed the effects of seed shape, temperature, and light treatment on the germination of eight species of medicinal crops to produce high-value crops in vertical farms. Eight species of medicinal seeds were selected, and the seed shape, seed length, seed width, seed length/width ratio, and one hundred seed weight were measured. The seed moisture content was confirmed. Eight species of medicinal seeds were sown, and the germination rate, germination energy, mean daily germination, and mean germination time were investigated according to temperature (15, 20, 25, 25/15℃) and light treatment. Each of the eight medicinal seeds showed different seed shapes. The moisture content of the seeds showed a moisture content rate of over 20% in the five medicinal seeds. Medicinal seeds that showed a germination rate of over 50% were Angelica gigas Nakai, Codonopsis lanceolata (Siebold & Zucc.) Benth. & Hook.f. ex Trautv., and Achyranthes bidentata Blume var. japonica Miq. seeds. A. gigas seed showed a germination rate of 67.34 ± 4.38% under 25/15℃ light conditions, and C. lanceolata seed showed a germination rate of over 50% under both temperature and light treatment conditions, especially the highest germination rate of 82.67 ± 1.46% under 15℃ dark conditions. Peucedanum japonicum Thunb. seed showed a germination rate of 52.34 ± 1.77% under dark conditions at 20℃, and the highest germination rate was 51.67 ± 3.79% under dark conditions at 15℃. The maximum germination energy was 74.00 ± 4.94% in C. lanceolata seed. The maximum mean daily germination was 14.94 ± 0.15 days in P. japonicum seed. Astragalus penduliflorus Lam. var. dahuricus (DC.) X.Y.Zhu seed showed the highest mean germination time of 34.19 ± 4.71. Through this study, it was determined that A. gigas, C. lanceolata, and A. penduliflours seeds would be suitable for production in vertical farms based on the characteristics of each medicinal seed through analysis of seed germination characteristics.

• Nuclear Medicine and Molecular Imaging
• /
• v.40 no.6
• /
• pp.293-301
• /
• 2006

Purpose: The aim of the study was to evaluate the hemodynamic changes after successful bypass surgery in patients with atherosclerotic stenosis in ICA using $^{99m}Tc-ECD$ SPECT. Materials and Methods: Fourteen patients (M:F=8:6, mean age; $60{\pm}9$ years) who underwent STA-MCA anastomosis for unilateral atherosclerotic cerebrovascular disease were enrolled. $^{99m}Tc-ECD$ basal/acetazolamide perfusion SPECT studies were performed before, 10 days and 6 months after bypass surgery. Perfusion reserve was defined as the % changes after acetazolamide over rest image. Regional cerebral blood flow and perfusion reserve were compared preoperative, early-postoperative and late-postoperative scans. Results: The mean resting perfusion and decrease in perfusion reserve in affected ICA territory on preoperative scan was $52.4{\pm}3.5\;and\;-7.9{\pm}4.7%$, respectively. The resting perfusion was significantly improved after surgery on early-postoperative scan (mean $53.7{\pm}2.7$) and late-postoperative scan (mean $53.3{\pm}2.5$) compared with preoperative images (p<0.05, respectively). Resting perfusion did not showed further improvement on late-postoperative scan compared with early-postoperative scan. The perfusion reserve was $-3.7{\pm}2.6%$ on early-postoperative scan, and $-1.6{\pm}2.3%$ on late-postoperative scan, which was significantly improved after surgery. Additionally, further improvement of perfusion reserved as observed on late-postoperative scan (p<0.05). While, in the unaffected ICA territory, no significant changes in the resting perfusion and perfusion reserve was observed. Conclusion: The improvement of resting perfusion and perfusion reserve in early-postoperative scan reflects the immediate restoration of the cerebral blood flow by bypass surgery. In contrasts, further improvement of perfusion reserve showing on late-postoperative scan may indicate a good collateral development after surgery, which may indicate good surgical outcome after surgery.

• Sleep Medicine and Psychophysiology
• /
• v.5 no.1
• /
• pp.103-110
• /
• 1998

Objectives : High co-morbidity of periodic limb movements during sleep(PLMS) and obstructive sleep apnea syndrome(OSAS) is well known and their incidences tend to increase in the elderly. Previous studies have inconsistently rep0l1ed increase or no change of periodic limb movement index(PLMI) by nasal continuous positive airway pressure(CPAP) in OSAS without analyzing possible variables affecting PLMI. We attempted to examine PLMI change evoked during CPAP titration and also factors affecting it in OSAS. Methods : Twenty-nine OSAS patients(M:F=26:3, mean age: $51.6{\pm}10.6\;yrs$) without other sleep disorders except for PLMS were selected, based on the nocturnal (baseline) polysomnograhy. Another night of noctumal polysomnography was performed for CPAP pressure titration. We compared between those two nights PLMI, mean and lowest $SaO_2$, and sleep variables. We also calculated PLMI differences between baseline and CPAP nights, named as delta PLMI (value of CPAP night PLMI minus value of baseline night PLMI). Correlations were calculated between delta PLMI and factors such as age, body mass index, applied CPAP pressure, baseline night values of respiratory disturbance index, mean and lowest $SaO_2$, and sleep parameter differences between baseline and CPAP nights. Results : Decrease of RDI(p<.01) and increase in mean and lowest $SaO_2$ (p<.05, p<.01) were observed during CPAP night. No sleep parameters showed significant change except for the decrease of total stage 1 sleep%(p<.01) during CPAP night. Ten out of 29 patients showed PLMI increase, while the other 19 patients showed either no change(n=14) or even PLMI decrease(n=5) during CPAP night. The 10 patients showing PLMI increase during CPAP night showed a significant positive correlation between delta PLMI and baseline night RDI(p<.05), which meant that PLMI increase was found to be more prominent in higher RDI patients than in lower RDI ones. There were no significant correlations between delta PLMI and other factors in the other 19 patients. Conclusions : We suggest that during the baseline night PLMS would have been underscored and/or masked due to the overlapping of PLMS and apneas/hypopneas or the arousals induced by apneas/hypopneas. Despite its still unknown mechanism, the CPAP application may unmask PLMS and increase PLMI in a subgroup of OSAS patients. It needs to be evaluated further whether the chronic CPAP use sustains the above finding.

• Korean Journal of Poultry Science
• /
• v.44 no.3
• /
• pp.189-198
• /
• 2017

This study was conducted to develop a new synthetic breed of Korean native chicken. The combining ability and reciprocal effects for production traits were estimated on 1,157 hens from a $5{\times}5$ diallel cross-mating design using grand parent stock (GPS) lines of Korean native chicken. Body weight, viability, age at first egg laying, egg weight, and hen-day egg production were measured and analyzed. The results showed that the general combining ability (GCA) of the survival rate during laying periods was -9.6 to 11.1, with the highest value obtained in the W strain. Additionally, the GCA of the body weight at 12 weeks was -209.7 to 162.2, with the highest value obtained in the F strain. The GCA for age at fist egg laying was estimated to be -2.8 to 3.7, while the GCA of egg weight was -0.91 to 0.96, and the GCA of hen-day egg production was -4.9 to 6.0. In the estimation of specific combining ability, the YW combination showed the highest survival rate, FW showed the highest body weight at 12 weeks, and GW showed the highest hen-day egg production. The reciprocal effects were significantly different among crosses for almost all productivity traits. In identical breeding combinations, differences in ability were observed when the maternal or paternal breeds were switched. The mean value based on combining ability was higher in WY, WF, and GW combinations for survival rate; GF, HG, and HF combinations for body weight at 12 weeks; and GW, YW, and FW combinations for hen-day egg production. It is concluded that the GF and HF combinations, which have excellent growth performance and moderate survival rate, are the most desirable paternal parent stock (PS) strains, and the GW and FW combinations, which have great laying performance and moderate body weight, are the most desirable maternal PS strains.

• Journal of Korean Society of Occupational and Environmental Hygiene
• /
• v.34 no.1
• /
• pp.67-76
• /
• 2024

Objectives: Direct reading instruments (DRIs) are widely used by industrial hygienists and other experts for preliminary survey and identifying source locations in many industrial fields. Photoionization detectors (PIDs), which are a form of hand-held portable DRIs, have been used for a variety of airborne vaporized chemicals, especially evaporated hydrocarbon solvents. The benefits of PIDs are high sensitivity between each chemical, competitive price, and portability. With the goal of increasing the accuracy of logged PID concentrations, previous studies have performed tests for the assessment of single chemical compounds, not mixtures. The purpose of this preliminary study was to measure mixtures with a PID and charcoal tube at the same time and compare the accuracy between them. Methods: A chamber test was implemented with different mixtures of hydrocarbon chemicals (acetone, isopropyl alcohol, toluene, m-xylene) and levels in the range of 14 to 864 ppm. Three PIDs and charcoal tubes were connected to the chamber and measured the chemical mixtures simultaneously. A comparison of accuracy and the PID group of concentrations with manufacture correction factor (M_CF) and field correction factor (F_CF) applied was performed. Results: The accuracy of the PID concentrations data-logged from the PID did not meet the accuracy criteria except for the mixture level B and C logged from PID No. 2, which was 18% of all tests for meeting accuracy criteria. The mean and standard deviation (SD) of concentration (ppm) of the charcoal tube followed by each mixtures' level were 10.37±0.26, 155.33±5.28, 300.80±11.65, and 774.93±22.65, respectively. When applying F_CF into the PID concentrations, the accuracy increased by nearly 82%. However, in the case of M_CF, none met the accuracy criterion. Between the PID there were differences of logged concentrations. Conclusions: In this preliminary study, the concentration of a logged PID with F_CF applied was a better way to increase accuracy compared to applying M_CF. We suggest that additional research is necessary to consider environmental factors such as temperature and humidity.

• Clinical and Experimental Pediatrics
• /
• v.52 no.3
• /
• pp.339-345
• /
• 2009

Purpose : This study aimed to determine the variation in parameters according to cardiac cycle length (CL; time interval between the QRS peaks on ECG) in children by using the conventional pulsed Doppler and tissue Doppler imaging echocardiography. Methods : Eighteen children with an anatomically normal heart were enrolled for the study. All children were examined by conventional and pulsed Doppler echocardiography at Gangneung Asan hospital between July 2006 and June 2007. We measured the CLs, mitral inflow velocities (E,A) and tissue Doppler imaging (TDI) parameters (s', e', a') from apical 4-chamber view. The TDI parameters were measured at the lateral (Lat) and septal (Sep) part of the mitral valve. All parameters were measured at 6 to 18 consecutive beats from each child. We then evaluated the linear correlation between CL and each parameter. Results : The mean age was $3.6{\pm}0.5$ years (M:F=8:10). There were significantly negative linear correlations between CL and A, Lat s', Lat a', Sep s', Sep e', Sep a' (P<0.01). There were significantly positive linear correlations between CL and E/A, Lat e'/a', Sep e'/a' (P<0.01). However, the E and Lat e' were not correlated with CL (P=0.229 and 0.221, respectively). Conclusion : This study showed that the values of the left ventricular functional parameters were changed according to CL. From our results, it is imperative to carefully examine beat-to-beat variations in children.

• Journal of Environmental Impact Assessment
• /
• v.27 no.6
• /
• pp.674-684
• /
• 2018

The purpose of this study is to construct ecological pond using LID technique in order to create naturally comfortable community space in urban idle space. The specification of the ecological pond is $110m^2$ of surface area, $0.45{\pm}0.02m$ of average depth, and bed material is composed of gravel (diameter ${\leq}60mm$), sand (diameter ${\leq}2mm$) and bentonite. Rainfall and water depth monitoring were conducted to determine the annual characteristics of inflow of the water for the ecological pond, result of total rainfall was 1,287 mm and showed a seasonal imbalance that accounted for 71.3% (918 mm) during July to August, but the annual mean water depth was kept constant at $0.45{\pm}0.02m$ due to the secondary water source. Annual trends of basic water quality showed a significant changes according to the season, such as water temperature ($5.2{\sim}28.8^{\circ}C$), DO (5.0 ~ 13.8 mg/L), EC ($113{\sim}265{\mu}S/cm$). BOD, COD, TN, and TP in physicochemical water quality tended to increase after October, but the ion parameters such as $NH_3$ and $PO_4{^{3-}}$ were generally low. Phytoplankton indicators Chl-a and BGA (blue green algae) showed a sharp increase from July to August, and green algae (Selenastrum bibraianum, Pediastrum boryanum etc.) and filamentous blue green algae (Phormidium sp.) emerged as a dominant species. The ion parameters ($F^-$, $Na^+$, $K^+$, $Mg^{2+}$, $Ca^{2+}$) were strongly correlated with the $Cl^-$ as a conservative substance (R=0.70~0.97, p<0.05). Water quality was influenced by the ambient environment such as seasonal changes or rainfall, and it was closely related to fluctuation of the inflow of the water. In the future, it is necessary to consider ecological connections by referring to the characteristics surveyed in this study in order to effectively manage the water quality and biodiversity of the ecological pond in idle space.